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| Product | Description | |
|---|---|---|
| E3330 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| E3330 | E3330 (APX-3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. E3330 is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer. E3330 shows anticancer activities. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 136164-66-4. Molecular formula: C21H30O6. Mole weight: 378.46. Purity: 0.9934. Canonical SMILES: CCCCCCCCC/C(C(O)=O)=C\C1=C(C)C(C(OC)=C(OC)C1=O)=O. Product ID: ACM136164664. Alfa Chemistry ISO 9001:2015 Certified. Categories: E330. |  |
| E3330 | E3330 is a potent and selective APE1 (Ref-1) inhibitor, which inhibits NF-κB DNA-binding activity. It blocks TNF-α-induced activation of IL-8 production in liver cancer cell lines and has anticancer properties such as inhibiting the growth and migration of cancer cells. Synonyms: APX-3330; E-3330; E 3330; (2E)-2-[(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene]-undecanoic acid; (E)-2-((4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylene)undecanoic acid; Undecanoic acid, 2-((4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene)-, (E)-. Grades: 98%. CAS No. 136164-66-4. Molecular formula: C21H30O6. Mole weight: 378.46. |  |
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