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EC 114 is a high affinity, potent and selective Hsp90 inhibitor. IC50 1.1 nM. It exhibits selectivity for Hsp90 over Grp94 and TRAP1 (Ki values are 61 and 255 nM respectively) and has no effect (IC50 > 10μM) against a panel of 285 kinases. Degrades Her-2 in MCF-7 breast cancer cells (EC50 = 14 nM). Blocks tumor growth and induces partial tumor regression in an N87 gastric tumor mouse model. Also inhibits LPS-induced TNFα release in an LPS shock mouse model and suppresses disease development in a rat model of collagen-induced arthritis. Exhibits < 20-fold efficacy over BIIB 021 in mice. Orally available and brain penetrant. Synonyms: EC144; EC-144; EC 144; Alkyne 40; Alkyne-40; Alkyne40. Grades:>98%. CAS No. 911397-80-3. Molecular formula: C21H24ClN5O2. Mole weight: 413.90.
EC 144
EC 144. Group: Biochemicals. Grades: Purified. CAS No. 911397-80-3. Pack Sizes: 10mg. US Biological Life Sciences.
This reaction is part of the pathway for synthesis of benzophenanthridine alkaloids in plants. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.119. CAS No. 144388-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1718; 10-hydroxydihydrosanguinarine 10-O-methyltransferase; EC 2.1.1.119; 144388-39-6. Cat No: EXWM-1718.
1,1,2,2-Tetrafluoroethoxyethene
1,1,2,2-Tetrafluoroethoxyethene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 211-654-3, CID69625, (1,1,2,2-Tetrafluoroethoxy)ethylene, 681-49-2. Product Category: Heterocyclic Organic Compound. CAS No. 681-49-2. Molecular formula: C4H4F4O. Mole weight: 144.068 g/mol. Purity: 0.96. IUPACName: 1-ethenoxy-1,1,2,2-tetrafluoroethane. Canonical SMILES: C=COC(C(F)F)(F)F. Density: 1.218g/cm³. ECNumber: 211-654-3. Product ID: ACM681492. Alfa Chemistry ISO 9001:2015 Certified.
1-Naphthalenesulfonicacid,8-(phenylamino)-,sodium salt(1:1). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Anilino-1-naphthalenesulfonic Acid Sodium Salt; sodium,8-anilinonaphthalene-1-sulfonate; ANS-Na. Product Category: Heterocyclic Organic Compound. CAS No. 1445-19-8. Molecular formula: C16H13NO3S.Na. Mole weight: 321.33. Purity: >97.0%(N). IUPACName: 8-(anilino)naphthalene-1-sulfonic acid. Canonical SMILES: C1=CC=C(C=C1)NC2=CC=CC3=C2C(=CC=C3)S(=O)(=O)[O-].[Na+]. Density: 1.409g/cm³. ECNumber: 215-890-8. Product ID: ACM1445198. Alfa Chemistry ISO 9001:2015 Certified.
1-Phenyl-1-pentyne
1-Phenyl-1-pentyne. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Phenyl-1-pentyne, 1-Pentynylbenzene, Benzene, 1-pentynyl-, 360104_ALDRICH, EINECS 224-211-4, SBB008966, 4250-81-1, InChI=1/C11H12/c1-2-3-5-8-11-9-6-4-7-10-11/h4,6-7,9-10H,2-3H2,1H. Product Category: Heterocyclic Organic Compound. Appearance: clear colorless to yellow liquid. CAS No. 4250-81-1. Molecular formula: C6H5CCCH2CH2CH3. Mole weight: 144.21. Purity: 0.96. IUPACName: pent-1-ynylbenzene. Canonical SMILES: CCCC#CC1=CC=CC=C1. Density: 0.903. ECNumber: 224-211-4. Product ID: ACM4250811. Alfa Chemistry ISO 9001:2015 Certified.
2,2,4-Trimethyl-1,3-pentanediol
2,2,4-Trimethyl-1,3-pentanediol. Uses: This product is suitable for scientific research. Additional or Alternative Names: Trimethyl-1,3-pentanediol;1,3-Pentanediol, 2,2,4-trimethyl-. Product Category: Polymer/MacromoleculeAlcohol-Difunctional. Appearance: White Crystalline Powder. CAS No. 144-19-4. Molecular formula: C8H18O2. Mole weight: 146.23 g/mol. Purity: 0.97. IUPACName: 2,2,4-trimethylpentane-1,3-diol. Canonical SMILES: CC(C)C(C(C)(C)CO)O. Density: 0.9±0.1 g/cm3. ECNumber: 205-619-1. Product ID: ACM-MO-144194. Alfa Chemistry ISO 9001:2015 Certified.
3,4-Bis(hydroxymethyl)furan
3,4-Bis(hydroxymethyl)furan. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Furandimethanol, Furan-3,4-diyldimethanol, EINECS 238-505-5, CID84477, InChI=1/C6H8O3/c7-1-5-3-9-4-6(5)2-8/h3-4,7-8H,1-2H, 14496-24-3. Product Category: Heterocyclic Organic Compound. CAS No. 14496-24-3. Molecular formula: C6H8O3. Mole weight: 128.13. Purity: 0.96. IUPACName: [4-(hydroxymethyl)furan-3-yl]methanol. Canonical SMILES: C1=C(C(=CO1)CO)CO. Density: 1.283g/cm³. ECNumber: 238-505-5. Product ID: ACM14496243. Alfa Chemistry ISO 9001:2015 Certified.
3-Methyl-3-Octanol
3-Methyl-3-Octanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Amylethylmethylcarbinol, 3-Octanol, 3-methyl-, 2-Ethyl-2-heptanol, 3-Methyloctan-3-ol, 3-METHYL-3-OCTANOL, Aprol 161, NSC903, NSC 903, 533890_ALDRICH, EINECS 226-276-4, MolPort-003-913-302, CID21432, BRN 1733747, AI3-24904, LS-98021, ST5410366, 4-01-00-01807 (Beilstein Handbook Reference), 5340-36-3, 138051-58-8. Product Category: Alcohols. CAS No. 5340-36-3. Molecular formula: C9H20O. Mole weight: 144.25. Purity: 0.96. IUPACName: 3-methyloctan-3-ol. Canonical SMILES: CCCCCC(C)(CC)O. Density: 0.825g/cm³. ECNumber: 226-276-4. Product ID: ACM5340363. Alfa Chemistry ISO 9001:2015 Certified.
3-Methylpentyl acetate
3-Methylpentyl acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-METHYL-1-PENTANOL ACETATE;3-METHYLPENTYL ACETATE;ACETIC ACID 3-METHYLPENTYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 35897-13-3. Molecular formula: C8H16O2. Mole weight: 144.21. Purity: 0.96. IUPACName: 3-methylpentyl acetate. Canonical SMILES: CCC(C)CCOC(=O)C. Density: 0.88. ECNumber: 252-785-6. Product ID: ACM35897133. Alfa Chemistry ISO 9001:2015 Certified.
4-hydroxyquinoline 3-monooxygenase
Quinolin-4-ol exists largely as the quinolin-4(1H)-one tautomer. Group: Enzymes. Synonyms: quinolin-4(1H)-one 3-monooxygenase. Enzyme Commission Number: EC 1.14.13.62. CAS No. 144378-37-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0869; 4-hydroxyquinoline 3-monooxygenase; EC 1.14.13.62; 144378-37-0; quinolin-4(1H)-one 3-monooxygenase. Cat No: EXWM-0869.
4-Methyl-2-propyl-1,3-dioxane
4-Methyl-2-propyl-1,3-dioxane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Methyl-2-propyl-1,3-dioxane, m-Dioxane, 4-methyl-2-propyl-, 2-Propyl-4-methyl-1,3-dioxane, 1,3-Dioxane, 4-methyl-2-propyl-, SBB060972, 1745-87-5, Butyraldehyde-1,3-butylene glycol acetal, Butyraldehyde, 1,3-butylene glycol acetal, 1, 4-methyl-2-propyl-, AC1L3U8L, AC1Q6ZI0, SureCN1108326, NSC6986, NSC 6986, NSC-6986, EINECS 217-120-6, AR-1G3422, AKOS006295331, AI3-22817, ST51047058. Product Category: Heterocyclic Organic Compound. CAS No. 1745-87-5. Molecular formula: C8H16O2. Mole weight: 144.211 g/mol. Purity: 0.96. IUPACName: 4-methyl-2-propyl-1,3-dioxane. Canonical SMILES: CCCC1OCCC(O1)C. Density: 0.886g/cm³. ECNumber: 217-120-6. Product ID: ACM1745875. Alfa Chemistry ISO 9001:2015 Certified.
5β-Cholanic acid-3α,7α,12α-triol methyl ester
5β-Cholanic acid-3α,7α,12α-triol methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHOLIC ACID METHYL ESTER; Methyl Cholate; Cholic acid methyl ester. Product Category: Steroidal Compounds. Appearance: Off-White Solid. CAS No. 1448-36-8. Molecular formula: C25H42O5. Mole weight: 422.61. Purity: 0.98. IUPACName: methyl(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Canonical SMILES: CC(CCC(=O)OC)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C. Density: 1.141g/cm³. ECNumber: 215-903-7. Product ID: ACM1448368. Alfa Chemistry ISO 9001:2015 Certified.
5-Chloro-3-fluorotoluene
5-Chloro-3-fluorotoluene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Chloro-5-fluorotoluene, EINECS 299-224-1, MolPort-001-776-347, PC5312, CID3022684, 93857-90-0. Product Category: Heterocyclic Organic Compound. CAS No. 93857-90-0. Molecular formula: C7H6ClF. Mole weight: 144.573943 [g/mol]. Purity: 0.96. IUPACName: 1-chloro-3-fluoro-5-methylbenzene. Canonical SMILES: CC1=CC(=CC(=C1)Cl)F. Density: 1.186g/cm³. ECNumber: 299-224-1. Product ID: ACM93857900. Alfa Chemistry ISO 9001:2015 Certified.
7-Octene-1,2-diol
7-Octene-1,2-diol. Uses: This product is suitable for scientific research. Additional or Alternative Names: oct-7-ene-1,2-diol. Product Category: Polymer/MacromoleculeAlcohol-Difunctional. CAS No. 85866-02-0. Molecular formula: C8H16O2. Mole weight: 144.21 g/mol. Purity: 0.97. IUPACName: oct-7-ene-1,2-diol. Canonical SMILES: OCC(O)CCCCC=C. Density: 0.941 g/mL at 25 °C (lit.). ECNumber: 288-704-6. Product ID: ACM-MO-85866020. Alfa Chemistry ISO 9001:2015 Certified.
8-Aminoquinoline, 98%
8-Aminoquinoline, 98%. Uses: 8-aminoquinoline has been used in: preparation of base-stabilized terminal borylene complex of osmium spectrophotometric determination of bivalent palladium. Additional or Alternative Names: DTXSID4060369; AN-21475; AC1Q51CD; A3000/0126362; 8-amino quinoline; PS-5383; PubChem7574; quinolin-8-yl-amine; RTC-062235; AB00375631-02. Product Category: Quinolines. CAS No. 578-66-5. Molecular formula: C9H8N2. Mole weight: 144.177g/mol. IUPACName: quinolin-8-amine. Canonical SMILES: C1=CC2=C(C(=C1)N)N=CC=C2. ECNumber: 209-427-9. Product ID: ACM578665. Alfa Chemistry ISO 9001:2015 Certified.
ALS-8176 (active form)
ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneALS-8176 (active form); ALS-8112; ALS8112; ALS 8112. UNII-7795987MKM7795987MKMCHEMBL3417243SCH EMBL15070479CS-5472; HY-12983; CS 5472; HY 12983; CS5472; HY129834'-Chloromethyl-2'-deoxy-2'-fluorocytidineCytidine. Grades: 99.67%. CAS No. 1445379-92-9. Molecular formula: C10H13ClFN3O4. Mole weight: 293.68.
AM-2394
AM-2394 is a selective Glucokinase agonist (GKA), It activates GK with an EC50 value of 60 nM. AM-2394 increases the affinity of GK for glucose by approximately 10-fold. It shows moderate clearance and good oral bioavailability in animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. Uses: Diabetes. Synonyms: AM-2394; AM 2394; AM2394; 1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea. Grades: 98%. CAS No. 1442684-77-6. Molecular formula: C22H25N5O4. Mole weight: 423.47.
arylmalonate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: AMDASE; 2-aryl-2-methylmalonate carboxy-lyase; 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming). Enzyme Commission Number: EC 4.1.1.76. CAS No. 144713-36-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4824; arylmalonate decarboxylase; EC 4.1.1.76; 144713-36-0; AMDASE; 2-aryl-2-methylmalonate carboxy-lyase; 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming). Cat No: EXWM-4824.
berbamunine synthase
A heme-thiolate enzyme (P-450). Forms the bisbenzylisoquinoline alkaloid berbamunine by phenol oxidation of N-methylcoclaurine without the incorporation of oxygen into the product. Reaction of two molecules of (R)-N-methylcoclaurine gives the dimer guattagaumerine. Group: Enzymes. Synonyms: (S)-N-methylcoclaurine oxidase (C-O phenol-coupling). Enzyme Commission Number: EC 1.14.21.3. CAS No. 144941-42-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1025; berbamunine synthase; EC 1.14.21.3; 144941-42-4; (S)-N-methylcoclaurine oxidase (C-O phenol-coupling). Cat No: EXWM-1025.
Bis[bis-(2-ethylhexyl)dithiocarbamato-s,s']nickel
Bis[bis-(2-ethylhexyl)dithiocarbamato-s,s']nickel. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID85732, EINECS 238-400-4, Nickel di-2-ethylhexyldithiocarbamate, Di-2-ethylhexyldithiocarbamic acid, nickel salt, Bis(bis(2-ethylhexyl)dithiocarbamato-S,S)nickel, Nickel, bis(bis(2-ethylhexyl)carbamodithioato-kappaS,kappaS)-, Nickel, bis(N,N-bis(2-ethylhexyl)carbamodithioato-kappaS,kappaS)-, 14428-08-1, 6014-72-8. Product Category: Heterocyclic Organic Compound. CAS No. 14428-08-1. Molecular formula: C34H68N2NiS4. Mole weight: 691.870520 [g/mol]. Purity: 0.96. IUPACName: N,N-bis(2-ethylhexyl)carbamodithioate; nickel(2+). Canonical SMILES: CCCCC(CC)CN(CC(CC)CCCC)C(=S)[S-].CCCCC(CC)CN(CC(CC)CCCC)C(=S)[S-].[Ni+2]. ECNumber: 238-400-4. Product ID: ACM14428081. Alfa Chemistry ISO 9001:2015 Certified.
Butanoic acid,2-methyl-,pentyl ester
Butanoic acid,2-methyl-,pentyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Amyl 2-methylbutyrate, Pentyl 2-methylbutyrate, n-Amyl 2-methylbutyrate, Butanoic acid, 2-methyl-, pentyl ester, EINECS 268-244-2, CID107059, 144810-16-2, 68039-26-9. Product Category: Heterocyclic Organic Compound. Appearance: Colorless Liquid. CAS No. 68039-26-9. Molecular formula: C10H20O2. Mole weight: 172.2646. Purity: 0.96. IUPACName: pentyl 2-methylbutanoate. Canonical SMILES: CCCCCOC(=O)C(C)CC. Density: 0.872 g/cm³. ECNumber: 268-244-2. Product ID: ACM68039269. Alfa Chemistry ISO 9001:2015 Certified.
Chlorohydroquinone
Chlorohydroquinone. Uses: This product is suitable for scientific research. Additional or Alternative Names: 2-Chloro-1,4-dihydroxybenzene. Product Category: Polymer/Macromolecule. CAS No. 615-67-8. Molecular formula: ClC6H3-1,4-(OH)2. Mole weight: 144.56. Purity: 0.95. Canonical SMILES: Oc1ccc(O)c(Cl)c1. ECNumber: 210-442-8. Product ID: ACM615678-1. Alfa Chemistry ISO 9001:2015 Certified.
cis-1,5-Cyclooctanediol,98%
cis-1,5-Cyclooctanediol,98%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,5-Cyclooctanediol, cis-1,5-Cyclooctanediol, cis-Cyclooctane-1,5-diol, 1,5-Cyclooctanediol, cis-, 179035_ALDRICH, MolPort-003-927-267, MolPort-005-980-973, ZINC04528580, CID90092, EINECS 245-649-2, AN-584/42206208, 23418-82-8. Product Category: Heterocyclic Organic Compound. CAS No. 23418-82-8. Molecular formula: C8H16O2. Mole weight: 144.21. Purity: 0.96. IUPACName: cyclooctane-1,5-diol. Canonical SMILES: C1CC(CCCC(C1)O)O. Density: 1.061g/cm³. ECNumber: 245-649-2. Product ID: ACM23418828. Alfa Chemistry ISO 9001:2015 Certified.
CPI203
CPI203, also known as TEN010, JQ-2; RO6870810 and RG6146, is a potent and orally active BET bromodomain inhibitor. CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors. CPI203 ownregulates Myc expression, causes G1 cell cycle arrest and attenuates cell proliferation in human pancreatic neuroendocrine tumors. CPI203 arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.9. Purity: >98%. IUPACName: (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide. Canonical SMILES: O=C(N)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1. Product ID: ACM1446144042. Alfa Chemistry ISO 9001:2015 Certified.
CPI-203
CPI-203 is a BET bromodomain inhibitor. It inhibits BRD4 in vitro and in cells, and causes G1 cell cycle arrest. It also arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Synonyms: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. Grades: >98%. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.90.
CYM 5520
CYM 5520 is a selective allosteric agonist of S1P2 (EC50 = 0.48 μM). It is selective for S1P2 receptors over a panel of 29 other receptors and transporters. Synonyms: 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile. Grades: ≥95%. CAS No. 1449747-00-5. Molecular formula: C21H19N3O2. Mole weight: 345.4.
Diaminedinitritopalladium(II)
Diaminedinitritopalladium(II). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 14286-03-4; DIAMMINEDINITROPLATINUM(II); 2NO2.Pd.2NH3; I14-42023; Diamminebis(nitrito-O)palladium; Diamminepalladium (II) nitrite; dinitrite; trans-Diamminedinitropalladium(II); 14409-60-0; 14852-83-6. Product Category: Palladium series catalysts. CAS No. 14708-52-2. Molecular formula: H6N4O4Pd. Mole weight: 232.492g/mol. IUPACName: azane;palladium(2+);dinitrite. Canonical SMILES: N.N.N(=O)[O-].N(=O)[O-].[Pd+2]. ECNumber: 238-388-0. Product ID: ACM14708522. Alfa Chemistry ISO 9001:2015 Certified.
Dihydro-5-(hydroxymethyl)-4,4-dimethylfuran-2(3H)-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 279-029-8, MolPort-003-891-642, CID3018797, Dihydro-5-(hydroxymethyl)-4,4-dimethylfuran-2(3H)-one, 78984-88-0. Product Category: Heterocyclic Organic Compound. CAS No. 78984-88-0. Molecular formula: C7H12O3. Mole weight: 144.16838. Purity: 0.96. IUPACName: 5-(hydroxymethyl)-4,4-dimethyloxolan-2-one. Canonical SMILES: CC1(CC(=O)OC1CO)C. Density: 1.082g/cm³. ECNumber: 279-029-8. Product ID: ACM78984880. Alfa Chemistry ISO 9001:2015 Certified.
dihydrosanguinarine 10-monooxygenase
A heme-thiolate protein (P-450) involved in benzophenanthridine alkaloid synthesis in higher plants. Group: Enzymes. Synonyms: dihydrosanguinarine 10-hydroxylase. Enzyme Commission Number: EC 1.14.13.56. CAS No. 144388-41-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0863; dihydrosanguinarine 10-monooxygenase; EC 1.14.13.56; 144388-41-0; dihydrosanguinarine 10-hydroxylase. Cat No: EXWM-0863.
FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6?1)-Peptide; 1H-Dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine Cyclic Peptide Deriv. Grades: ≥90%. CAS No. 144371-88-0. Molecular formula: C51H82N8O21S. Mole weight: 1175.30.
Furan,2,5-dihydro-2,5-dimethoxy-2-methyl-
Furan,2,5-dihydro-2,5-dimethoxy-2-methyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 392472_ALDRICH, EINECS 244-972-6, 2,5-Dihydro-2,5-dimethoxy-2-methylfuran, SB 01757, Furan, 2,5-dihydro-2,5-dimethoxy-2-methyl-, 22414-24-0. Product Category: Heterocyclic Organic Compound. CAS No. 22414-24-0. Molecular formula: C7H12O3. Mole weight: 144.17. Purity: 0.96. IUPACName: 2,5-dimethoxy-5-methyl-2H-furan. Canonical SMILES: CC1(C=CC(O1)OC)OC. Density: 1.019 g/mL at 25ºC(lit.). ECNumber: 244-972-6. Product ID: ACM22414240. Alfa Chemistry ISO 9001:2015 Certified.
A blood-brain barrier-permeable, non-toxic phenyl-pyrazolylurea compound that acts as a direct, potent, fast, and reversible activator of GIRK1 (G-protein activated inward-rectifying K+ channel containing subunit 1) containing channels (EC50 = 162, 914, and 887nM in Thallium influx assay for GIRK1/2, GIRK1/3, and GIRK1/4 expressed in HEK-293 cell lines). Its action does not require the presence of an activated Gi GPCR. Shown to be inactive towards GIRK2, GIRK2/3, Kir2.1, KV7.4 and GABAA, and weakly active against a panel of 61 other receptors, ion channels, enzymes, transporters, and proteins even at higher concentration (~10uM). Exhibits desirable pharmacokinetic properties with good solubility (17.5uM), predicted hepatic clearance (88 ml/min/kg), and Tmax of 640nM and 130nM in plasma and brain, respectively. Shown to reduce locomotor function and seizure frequency in electroshock- and chemically-induced murine epilepsy models (60mg/kg, i.p). Group: Biochemicals. Grades: Highly Purified. CAS No. 1443246-62-5. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O. US Biological Life Sciences.
Worldwide
GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808)
A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
HIV-1 retropepsin
Present in human immunodeficiency virus type 1. Contributes to the maturation of the viral particle, and is a target of antiviral drugs. Active enzyme is a dimer of identical 11-kDa subunits. Similar enzymes occur in other retroviruses. Type example of peptidase family A2. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4253; HIV-1 retropepsin; EC 3.4.23.16; 144114-21-6; human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Cat No: EXWM-4253.
HIV-2 retropepsin
In peptidase family A2. Responsible for the post-translational processing of the human immunodeficiency virus polyprotein. Group: Enzymes. Enzyme Commission Number: EC 3.4.23.47. CAS No. 144114-21-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4284; HIV-2 retropepsin; EC 3.4.23.47; 144114-21-6. Cat No: EXWM-4284.
HIV Protease Mutant, Recombinant
HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Mole weight: mol wt ~10.8 kDa. Storage: -70°C. Form: Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol. Source: E. coli. human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Pack: 100 unit vial containing > 100ug protein. Cat No: NATE-0344.
Ipsdienol
Ipsdienol. Uses: Ipsdienol is a racemic mixture of the pine bark beetle pheromone. Additional or Alternative Names: 2-Methyl-6-Methyleneocta-2,7-Dien-4-Ol. Product Category: Insect Pheromone. CAS No. 14434-41-4. Molecular formula: C10H16O. Mole weight: 152.24. Purity: 0.9. IUPACName: 2-methyl-6-methylideneocta-2,7-dien-4-ol. Canonical SMILES: CC(=CC(CC(=C)C=C)O)C. Density: 0.87g/cm³. ECNumber: 238-408-8. Product ID: ACM14434414. Alfa Chemistry ISO 9001:2015 Certified.
Isononanol
Isononanol. Uses: Designed for use in research and industrial production. Appearance: Clear liquid. CAS No. 27458-94-2. Molecular formula: C9H20O. Mole weight: 144.25. Purity: 0.99. IUPACName: 7-methyloctan-1-ol. Canonical SMILES: CC(C)CCCCCCO. Density: 0.824g/cm³. ECNumber: 248-471-3. Product ID: ACM27458942. Alfa Chemistry ISO 9001:2015 Certified.
lipoate-protein ligase
Requires Mg2+. This enzyme participates in lipoate salvage, and is responsible for lipoylation in the presence of exogenous lipoic acid. The enzyme attaches lipoic acid to the lipoyl domains of certain key enzymes involved in oxidative metabolism, including pyruvate dehydrogenase (E2 domain), 2-oxoglutarate dehydrogenase (E2 domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein). Lipoylation is essential for the function of these enzymes. The enzyme can also use octanoate instead of lipoate. Group: Enzymes. Synonyms: lplA (gene name); lplJ (gene name); lipoate protein ligase; lipoate-protein ligase A; LPL; LPL-B. Enzyme Commission Number: EC 6.3.1.20. CAS No. 144114-18-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5723; lipoate-protein ligase; EC 6.3.1.20; 144114-18-1; lplA (gene name); lplJ (gene name); lipoate protein ligase; lipoate-protein ligase A; LPL; LPL-B. Cat No: EXWM-5723.
L-tert-Leucine methylamide
L-tert-Leucine methylamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE, 89226-12-0, (S)-2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE, AC1MRP6C, 2-azanyl-N,3,3-trimethyl-butanamide, A843096. Product Category: Heterocyclic Organic Compound. CAS No. 89226-12-0. Molecular formula: C7H16N2O. Mole weight: 144.21. Purity: 0.96. IUPACName: 2-amino-N,3,3-trimethylbutanamide. Canonical SMILES: CC(C)(C)C(C(=O)NC)N. Density: 0.935g/cm³. ECNumber: 618-258-3. Product ID: ACM89226120. Alfa Chemistry ISO 9001:2015 Certified.
Magnesium citrate
Magnesium citrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MAGNESIUM CITRATE DIBASIC;magnesiumhydrogencitrate;MAGNESIUM CITRATE ANHYDROUS;CitricAcid,MagnesiumSalt,Dibasic;Magnesium citrate tetradecahydrate;1,2,3-Propanetricarboxylic acid, 2-hydroxy-, magnesium salt (1:1);Magnesium citrate dibasic, anhydrous;magn. Product Category: Alcohols. Appearance: White powder. CAS No. 144-23-0. Molecular formula: C12H10Mg3O14. Mole weight: 214.41. Purity: 0.96. IUPACName: magnesium 3-carboxy-3-hydroxypentanedioate. Canonical SMILES: C(C(=O)O)C(CC(=O)[O-])(C(=O)[O-])O.[Mg+2]. Density: g/cm³. ECNumber: 604-400-1. Product ID: ACM144230. Alfa Chemistry ISO 9001:2015 Certified.
mannitol dehydrogenase
The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation. The enzyme is specific for NAD+ and does not use NADP+. Group: Enzymes. Synonyms: MTD; NAD-dependent mannitol dehydrogenase. Enzyme Commission Number: EC 1.1.1.255. CAS No. 144941-29-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0160; mannitol dehydrogenase; EC 1.1.1.255; 144941-29-7; MTD; NAD-dependent mannitol dehydrogenase. Cat No: EXWM-0160.
Mannitol Dehydrogenase (Crude Enzyme)
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Diagnostics; biotechnology. Group: Enzymes. Synonyms: MTD; NAD-dependent mannitol dehydrogenase. Enzyme Commission Number: EC 1.1.1.255. CAS No. 144941-29-7. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. MTD; NAD-dependent mannitol dehydrogenase. Pack: 100ml. Cat No: NATE-1796.
Methyl 2,2-dimethylacetoacetate
Methyl 2,2-dimethylacetoacetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl 2,2-dimethylacetoacetate, CID96925, NSC93904, EINECS 254-189-1, Methyl 2,2-dimethyl-3-oxobutanoate, ZINC01609563, 2,2-Dimethyl-3-oxobutyric acid, methyl ester, Butanoic acid, 2,2-dimethyl-3-oxo-, methyl ester, 38923-57-8. Product Category: Heterocyclic Organic Compound. Appearance: Liquid. CAS No. 38923-57-8. Molecular formula: C7H12O3. Mole weight: 144.17. Purity: 0.96. IUPACName: methyl 2,2-dimethyl-3-oxobutanoate. Canonical SMILES: CC(=O)C(C)(C)C(=O)OC. Density: 0.999. ECNumber: 254-189-1. Product ID: ACM38923578. Alfa Chemistry ISO 9001:2015 Certified.
ML 297
ML 297 (VU 0456810) is a potent and selective GIRK 1/2 activator, with an EC 50 of 0.16 μM. ML 297 is potential for the treatment of epilepsy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VU 0456810; CID 56642816. CAS No. 1443246-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110192.
ML-314
Medicinal chemistry optimization of MLS-0233108 led to ML314, the most potent molecule in this second series that exhibited full agonist behavior (100 %) on NTR1 (EC50 = 1.9 μM). ML314 showed good selectivity against NTR2 and GPR35, but did not stimulate Ca2+ mobilization. ML314 is potentially a biased agonist operating via the β-arrestin pathway rather than the traditional Gq coupled pathway. Signaling mediated by β-arrestin has distinct biochemical and functional consequences that may lead to physiological advantages as described below. This probe report describes the discovery and properties of ML301 and summarizes the HTS and follow-up campaign, which identified ML314. Synonyms: ML 314; ML-314; ML314. Grades: 0.98. CAS No. 1448895-09-7. Molecular formula: C24H28N4O3. Mole weight: 420.513.
MRS 2693 trisodium salt
MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor), with no activity at other P2Y subtypes. Synonyms: Uridine 5'-(trihydrogen diphosphate), 5-iodo-, sodium salt (1:3); MRS 2693; 5-Iodo-UDP Trisodium Salt; 5-Iodouridine 5'-(trihydrogen diphosphate) sodium salt; 5-Iodouridine-5'-O-diphosphate trisodium salt; MRS2693; MRS-2693. Grades: ≥95% by HPLC. CAS No. 1448858-83-0. Molecular formula: C9H10IN2Na3O12P2. Mole weight: 596.00.
N,N-Diisopentylaniline
N,N-Diisopentylaniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N-Diisopentylaniline, EINECS 238-394-3, CID84428, 14426-16-5. Product Category: Heterocyclic Organic Compound. CAS No. 14426-16-5. Molecular formula: C16H27N. Mole weight: 233.392280 [g/mol]. Purity: 0.96. IUPACName: N,N-bis(3-methylbutyl)aniline. Canonical SMILES: CC(C)CCN(CCC(C)C)C1=CC=CC=C1. Density: 0.896g/cm³. ECNumber: 238-394-3. Product ID: ACM14426165. Alfa Chemistry ISO 9001:2015 Certified.
N,N,N',N'-Tetramethyl-1,3-butanediamine
N,N,N',N'-Tetramethyl-1,3-butanediamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tetramethylbutanediamine, NIAX catalyst TMBDA, 1,3-Bis(dimethylamino)butane, Tetramethyl butanediamine, Tetramethylbutane-1,3-diamine, CCRIS 4869, 14740_ALDRICH, N,N,N,N-Tetramethyl-1,3-diaminobutane, N,N,N,N-TETRAMETHYL-1,3-BUTANEDIAMINE, NSC35411, 14740_FLUKA, EINECS 202-610-4, 1,3-Butanediamine, N,N,N,N-tetramethyl-, CID7350, MolPort-003-926-533, NSC 35411, BRN 1698054, N,N,N1,N1-Tetramethyl-1,3-diaminobutane, 1,3-Diaminobutane, N,N,N,N-tetramethyl-, AI3-26039. Product Category: Heterocyclic Organic Compound. Appearance: Colorless to Light Yellow Liquid. CAS No. 97-84-7. Molecular formula: C8H20N2. Mole weight: 144.26. Purity: 0.98. IUPACName: 1-N,1-N,3-N,3-N-tetramethylbutane-1,3-diamine. Canonical SMILES: CC(CCN(C)C)N(C)C. Density: 0.787 g/mL at 25ºC(lit.). ECNumber: 202-610-4. Product ID: ACM97847. Alfa Chemistry ISO 9001:2015 Certified.
NVR 3-778
NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40?μM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos(t)ide inhibitors of HBV replication. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NVR 3 778; NVR3 778; NVR-3-778; K-89; K 89; K89; NVR3778; NVR 3778; NVR-3778. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1445790-55-5. Molecular formula: C18H16F4N2O4S. Mole weight: 432.39. Purity: >98%. IUPACName: 4-Fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide. Canonical SMILES: O=C(NC1=CC(F)=C(F)C(F)=C1)C2=CC=C(F)C(S(=O)(N3CCC(O)CC3)=O)=C2. Product ID: ACM1445790555. Alfa Chemistry ISO 9001:2015 Certified.
Involved in the first step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes. In mammalian cells, the enzyme is composed of at least five subunits (PIG-A, PIG-H, PIG-C, GPI1 and PIG-P). PIG-A subunit is the catalytic subunit. In some species, the long-chain acyl groups of the phosphatidyl group are partly replaced by long-chain alkyl or alk-1-enyl groups. Group: Enzymes. Synonyms: UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase; uridine diphosphoacetylglucosamine α1,6-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.198. CAS No. 144388-35-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2425; phosphatidylinositol N-acetylglucosaminyltransferase; EC 2.4.1.198; 144388-35-2; UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase; uridine diphosphoacetylglucosamine α1,6-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2425.
PM-1
PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1449483-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156404.
Potassium pentachlororuthenate(iII)hydrate
Potassium pentachlororuthenate(iII)hydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DIPOTASSIUM AQUAPENTACHLORORUTHENATE(II);DIPOTASSIUM AQUAPENTACHLORORUTHENATE(III);POTASSIUM PENTACHLOROAQUARUTHENIUM(III);POTASSIUM PENTACHLOROAQUORUTHENIUM(III);POTASSIUM PENTACHLORORUTHENATE (III);POTASSIUM PENTACHLORORUTHENATE(III) HYDRATE;POTASSIUM A. Product Category: Metal & Ceramic Materials. Appearance: brown needles. CAS No. 14404-33-2. Molecular formula: Cl5H2K2ORu. Mole weight: 374.55. Purity: 0.96. IUPACName: dipotassium;pentachlororuthenium(2-);hydrate. Canonical SMILES: O.Cl[Ru-2](Cl)(Cl)(Cl)Cl.[K+].[K+]. ECNumber: 238-374-4. Product ID: ACM14404332. Alfa Chemistry ISO 9001:2015 Certified.
Pyridazine,3-chloro-6-methoxy-
Pyridazine,3-chloro-6-methoxy-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-CHLORO-6-METHOXYPYRIDAZINE, Pyridazine, 3-chloro-6-methoxy-, 108596_ALDRICH, NSC69819, ALBB-010083, CID74403, 6-chloropyridazin-3-yl methyl ether, EINECS 217-019-7, NSC522667, SBB004124, ZINC00152973, TL8007194, AC-907/25014054, 1722-10-7, InChI=1/C5H5ClN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H. Product Category: Heterocyclic Organic Compound. Appearance: White to Beige Conforms to Requirement Powder or Crystals. CAS No. 1722-10-7. Molecular formula: C5H5ClN2O. Mole weight: 144.559. Purity: 0.96. IUPACName: 3-chloro-6-methoxypyridazine. Canonical SMILES: COC1=NN=C(C=C1)Cl. Density: 1.292 g/cm³. ECNumber: 217-019-7. Product ID: ACM1722107. Alfa Chemistry ISO 9001:2015 Certified.
Sodium allylsulfonate
Sodium allylsulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Propene-1-sulfonic acid, sodium salt. Product Category: Anionic Surfactants. Appearance: Liquid. CAS No. 2495-39-8. Molecular formula: C3H5NaO3S. Mole weight: 144.13. Purity: 35%+. IUPACName: Sodium;prop-2-ene-1-sulfonate. Canonical SMILES: C=CCS(=O)(=O)[O-].[Na+]. Density: 1.332 g/cm³. ECNumber: 219-676-5. Product ID: ACM2495398-2. Alfa Chemistry ISO 9001:2015 Certified.
Sodium bicarbonate
Sodium bicarbonate. Synonyms: Sodium hydrogen carbonate. CAS No. 144-55-8. Product ID: CDC10-0020. Molecular formula: NaHCO3. Category: Cosmetic Chemical Abrasives. Product Keywords: Cosmetic Ingredients; Cosmetic Chemical Abrasives; Sodium bicarbonate; CDC10-0020; 144-55-8; NaHCO3; Sodium hydrogen carbonate; 205-633-8; MFCD00003528; 144-55-8. Grade: ACS reagent. Purity: ≥99.7%. EC Number: 205-633-8. Physical State: Powder. Solubility: H2O: 1 M at 20 °C, clear, colorless. Quality Level: 300. Boiling Point: 851°C. Melting Point: >300 °C(lit.). Density: 2.16 g/mL at 25 °C (lit.).
Spirgetine
Spirgetine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: spirgetine;1-[2-(6-Azaspiro[2.5]oct-6-yl)ethyl]guanidine;2-[2-(6-azaspiro[2.5]octan-6-yl)ethyl]guanidine. Product Category: Heterocyclic Organic Compound. CAS No. 144-45-6. Molecular formula: C10H20N4. Mole weight: 196.292600 [g/mol]. Purity: 0.96. IUPACName: 2-[2-(6-azaspiro[2.5]octan-6-yl)ethyl]guanidine. Canonical SMILES: C1CC12CCN(CC2)CCN=C(N)N. Density: 1.3g/cm³. ECNumber: 205-629-6. Product ID: ACM144456. Alfa Chemistry ISO 9001:2015 Certified.
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5?10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63.
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