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| Product | Description | |
|---|---|---|
| Ecopipam | Ecopipam, a synthetic benzazepine derivative drug, acts as a selective dopamine D1/D5 receptor antagonist with little affinity for either dopamine D2-like or 5-HT2 receptors. It was developed by Schering plough. It is currently in clinical trials conducted by the biotechnology company Psyadon Pharmaceuticals for the treatment of Tourette syndrome in children. It has received FDA treatment of Lesch-Nyhan disease orphan drug certification. Uses: Ecopipam was used for the treatment of tourette syndrome in children. Synonyms: Sch 39166;(6aS)-11-Chloro-6,6aβ,7,8,9,13bα-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol;(6aβ,13bα)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol;5H-Benzo(D)naphth(2,1-B)azepin-12-ol, 11-chloro-6,6A,7,8,9,13B-hexahydro-7-methyl-, trans-(-)-;6, 7, 7A, 8, 9, 13B-Hexahydro-3-chloro-2-hydroxy-N-methyl-5H-benzo(D)naphtho(2, 1B)azepine;(6aS, 13bR)-11-chloro-7-methyl-5, 6, 6a, 8, 9, 13b-hexahydronaphtho[1, 2-a][3]benzazepin-12-ol;5H-Benzo(d)naphth(2, 1-b)azepin-12-ol, 11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-, (6aS,13bR)-. Grades: >98%. CAS No. 112108-01-7. Molecular formula: C19H20ClNO. Mole weight: 313.83. |  |
| Ecopipam hydrobromide | Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrobromide. CAS No. 2587360-22-1. Pack Sizes: 1 mg. Product ID: HY-110033. |  |
| Ecopipam hydrochloride | Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrochloride. CAS No. 190133-94-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14689. | |
| SCH 39166 hydrobromide | SCH 39166 hydrobromide is a high affinity dopamine D1/D5 receptor antagonist (Ki = 1.2, 2, 980, 5520, 80 and 731 nM for binding to D1, D5, D2, D4, 5-HT and α2a receptors, respectively). SCH 39166 is used in the treatment of schizophrenia, cocaine addiction and obesity. Uses: The treatment of schizophrenia, cocaine addiction and obesity. Synonyms: SCH 39166 hydrobromide; SCH39166 hydrobromide; SCH-39166 hydrobromide; (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide; Ecopipam hydrobromide. Grades: ≥99% by HPLC. CAS No. 1227675-51-5. Molecular formula: C19H20ClNO.HBr. Mole weight: 394.73. | |
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