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Edelfosine, an orally administered antileishmanial drug, has anti-metastasis effect in experimental tumors. Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. Uses: Phosphodiesterase inhibitors. Synonyms: ALP; 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide; 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine; ET-18-OMe; ET 18-OCH3; rac-1-Octadecyl-2-methoxyglycero-3-phosphocholine; NSC-324368; (±)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide inner salt 4-oxide. Grade: ≥95%. CAS No. 70641-51-9. Molecular formula: C27H58NO6P. Mole weight: 523.73.
Edelfosine
Edelfosine (ET-18-OCH3) is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ET-18-OCH3. CAS No. 70641-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108610A.
Edelfosine
Edelfosine. Group: Biochemicals. Grades: Purified. CAS No. 77286-66-9. Pack Sizes: 10mg. US Biological Life Sciences.
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(R)-Edelfosine
(R)-Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. It induces apoptosis in human promyelocytic HL-60 leukemic cells and promonocytic U937 leukemic cells. Synonyms: 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-; 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-; 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine; ET 18-OCH3; TLC ELL 12; (R)-2-methoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate; (7R)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4-oxide. Grade: >99%. CAS No. 77286-66-9. Molecular formula: C27H58NO6P. Mole weight: 523.73.
1-O-Octadecyl-2-O-methyl-rac-glycerol
1-O-Octadecyl-2-O-methyl-rac-glycerol is used to prepare Edelfosine, a rapid inducer of apoptosis in human leukemic cells. Edelfosine has been considered as a promising drug in cancer treatment. It is also used to prepare phospholipids containing nitrogen homologs with antitumor activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 84337-43-9. Pack Sizes: 50mg, 250mg. Molecular Formula: C22H46O3, Molecular Weight: 358.6. US Biological Life Sciences.