Eflornithine Suppliers USA
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Product | Description | |
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Eflornithine Quick inquiry Where to buy Suppliers range | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grades: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
Eflornithine Quick inquiry Where to buy Suppliers range | Eflornithine. CAS No. 70052-12-9. | |
Eflornithine hydrochloride Quick inquiry Where to buy Suppliers range | Eflornithine hydrochloride. Group: Biochemicals. Alternative Names: DFMO; DL-2-(Difluoromethyl)-ornithine hydrochloride. Grades: Highly Purified. CAS No. 68278-23-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C6H12F2N2O2·HCl. US Biological Life Sciences. | Worldwide |
Eflornithine hydrochloride Quick inquiry Where to buy Suppliers range | Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; MDL 71782 hydrochloride; RMI 71782 hydrochloride; MDL-71782 hydrochloride; RMI-71782 hydrochloride; α-difluoromethylornithine hydrochloride; Vaniqa hydrochloride. Grades: >98%. CAS No. 68278-23-9. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63. | |
Eflornithine hydrochloride, hydrate Quick inquiry Where to buy Suppliers range | Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate. Grades: 98%. CAS No. 96020-91-6. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
Eflornithine Hydrochloride Monoydrate Quick inquiry Where to buy Suppliers range | Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism. Group: Biochemicals. Alternative Names: 2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2- (Difluoromethyl) ornithine; DFMO; DL-2- (Difluoromethyl) ornithine; DL-α - (Difluoromethyl) ornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α , δ -Diamino-α - (difluoromethyl) valeric Acid; α-(Difluoromethyl)-DL-ornithine; α - (Difluoromethyl) ornithine. Grades: Highly Purified. CAS No. 96020-91-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??ClF?N?O?, Molecular Weight: 236.64. US Biological Life Sciences. | Worldwide |