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Egt1442 Egt1442. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EGT1442;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol;Bexagliflozin. Product Category: Heterocyclic Organic Compound. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 0. Density: 1.41. Product ID: ACM1118567057. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
EGT1442 EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival of SHRSP rats. It attenuates blood glucose and HbA(1c) levels and prolongs the survival of stroke-prone rats in db/db mice. It showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients. It was developed by Theracos and in clinic phase 1 trials. Uses: Egt1442 showed favorable properties and could be beneficial to the management of type 2 diabetic patients. Synonyms: THR1442; THR-1442; THR 1442; EGT1442; EGT-1442; EGT 1442; Bexagliflozin; (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[[4-[2- (cyclopropyloxy) ethoxy]phenyl]methyl]phenyl]-D-glucitol; Bexagliflozin; THR1442; EGT0001442; EGT-1442; THR-1442; EGT-0001442; (2S, 4R, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol; (3R, 4R, 5S, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol. Grades: >98%. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 464.94. BOC Sciences 10

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