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| Product | Description | |
|---|---|---|
| Elafibranor | Elafibranor (GFT505) is a PPARα/δ agonist with EC 50 s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16737. |  |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Synonyms: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E) -1-[4- (Methylthio) phenyl]-3-[3, 5-dimethyl-4-[ (carboxydimethylmethyl) oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49. |  |
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