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Encaleret Encaleret (CLTX-305) is an orally active CaSR antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CLTX-305. CAS No. 787583-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14401. MedChemExpress MCE
Encaleret Encaleret is a calcium-sensing receptor (CaSR) antagonist. But in Oct 2011, Phase-II for Osteoporosis in USA was discontinued. Uses: Osteoporosis. Synonyms: 1214922-52-7 (sulfate salt);JIT-305; JIT 305; JIT305; 2'-((R)-1-((R)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl-[1,1'-biphenyl]-4-carboxylic acid. Grades: 98%. CAS No. 787583-71-5. Molecular formula: C29H33ClFNO4. Mole weight: 514.03. BOC Sciences 10
ENCALERET SULFATE This active molecular is an CaSR (calcium-sensing receptor antagonist) under the developmet of Tobacco and Merck & Co. Calcium-sensing receptor is a member of the G protein-coupled receptor and it is very important to modulate Ca2+ homeostasis via its role in the parathyroid glands and kidneys. Encaleret was used for the treatment of osteoporosis., but was discontinued in Phase-II in Japan, India and USA in 2011. Uses: The treatment of osteoporosis. Synonyms: 4-[2-[(1R)-1-[(2R)-3-[[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]ethyl]phenyl]-2-methylbenzoic acid;sulfuric acid;hydrate; JIT305; JIT 305; JIT-305. Grades: 98%. CAS No. 1214922-52-7. Molecular formula: C58H70Cl2F2N2O13S. Mole weight: 1144.16. BOC Sciences 10

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