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Ensitrelvir fumarate Ensitrelvir, also known as S-217622, is an antiviral drug developed by Shionogi in partnership with Hokkaido University, which acts as an orally active 3C-like protease inhibitor for the treatment of COVID-19 infection. It is taken by mouth, and has been successfully tested against the recently emerged Omicron variant. It is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM). It became the first Japanese domestic pill to treat COVID-19, third to be regulatorally approved in Japan; in February 2022. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ensitrelvir fumarate; S-217622; S 217622; S217622; Xocova. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2757470-18-9. Molecular formula: C26H21ClF3N9O6. Mole weight: 647.96. Purity: >98%. IUPACName: (E)-6-((6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-((1-methyl-1H-1,2,4-triazol-3-yl)methyl)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazinane-2,4-dione fumaric acid. Canonical SMILES: O=C(N(CC1=NN(C)C=N1)C(N/2)=O)N(CC3=CC(F)=C(F)C=C3F)C2=N\C4=CC5=CN(C)N=C5C=C4Cl.O=C(O)/C=C/C(O)=O. Product ID: ACM2757470189. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Ensitrelvir fumarate Ensitrelvir (S-217622) fumarate is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor ( IC 50 =13 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-217622 fumarate. CAS No. 2757470-18-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143216A. MedChemExpress MCE

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