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An enantiomeric impurity of Ezetimibe. Group: Biochemicals. Alternative Names: (3S,4R)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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ent-Ezetimibe
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L3) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: R,S,R-Ezetimibe; (3S,4R)-1-(4-Fluorophenyl)-3-[(R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3S,4R)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Ezetimibe (3S,4R,3'R)-Isomer; Ezetimibe (RSR)-Isomer; ent-SCH 58235; (3S,4R,3'R)-Ezetimibe. Grade: >95%. CAS No. 1376614-99-1. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
ent-Ezetimibe
The lipid-lowering drug, the first and only cholesterol absorption inhibitor, effectively reduces intestinal cholesterol absorption and lowers plasma cholesterol levels as well as hepatic cholesterol stores through selective inhibition of small intestinal cholesterol transporter proteins. Alternative Names: (3S,4R)-1-(4-Fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. FST3D70Q0D. (3S,4R)-1-(4-FLUOROPHENYL)-3-[(3R)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)AZETIDIN-2-ONE. CAS No. 1376614-99-1. Product ID: API1376614991. Molecular formula: C24H21F2NO3. Mole weight: 409.4. SMILES: C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O. Standard: USP/BP/EP. Category: Lipid-Lowering APIs.
(3'S)-ent-Ezetimibe
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: S,S,R-Ezetimibe; (3S,4R)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3S,4R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZTRC-10 (SSR Isomer); Ezetimibe (3S,4R,3'S)-Isomer; (3S,4R,3'S)-Ezetimibe; Ezetimibe (SSR)-Isomer. Grade: >95%. CAS No. 1593543-00-0. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
(3S)-ent-Ezetimibe
An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinem ic and cholesterol absorption inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone is used in the preparation of ent-Ezetimibe (E975005) intermediates. Group: Biochemicals. Alternative Names: 1-(4-Fluorophenyl)-5-[(4R)-2-oxo-4-phenyl-3-oxazolidinyl]-1,5-pentanedione; (R)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one; (4R)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-1,3-oxazolidin-2-one. Grades: Highly Purified. CAS No. 404874-93-7. Pack Sizes: 500mg. US Biological Life Sciences.
(4R)-4-Phenyl-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one is used in the preparation of ent-Ezetimibe (E975005) intermediates. Group: Biochemicals. Alternative Names: 3-[(5R)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4R)-phenyl-1,3-oxazolidin-2-one. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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