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| Product | Description | |
|---|---|---|
| Entinostat | Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Synonyms: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[ (2-aminophenyl) carbamoyl]phenyl]methyl]carbamate. Grades: > 98%. CAS No. 209783-80-2. Molecular formula: C21H20N4O3. Mole weight: 376.416. |  |
| Entinostat | Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies. Group: Biochemicals. Alternative Names: N- [ [4- [ [ (2-Aminophenyl) amino] carbonyl] phenyl] methyl] carbamic Acid 3-Pyridinylmethyl Ester; (Pyridin-3-yl)methyl 4- (2-Aminophenylcarbamoyl) benzylcarbamate; MS 27-275; MS 275; MS 275-27; N-(2-Aminophenyl)-4-[N-(pyridine-3-yl-methoxycarbonyl)-aminomethyl]benzamide; SNDX 275. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Entinostat | Entinostat is an oral and selective class I HDAC inhibitor, with IC 50 s of 243 nM, 453 nM, and 248 nM for HDAC1 , HDAC2 , and HDAC3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MS-275; SNDX-275. CAS No. 209783-80-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12163. |  |
| MS-275 (Entinostat, SNDX-275) | Preferentially inhibits HDAC1 (IC50=300 nM) over HDAC3 (IC50=8uM). Has no inhibitory activity towards HDAC8 (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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