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| Product | Description | |
|---|---|---|
| 100 bp+50 bp DNA Ladder | 100 bp+50 bp DNA Ladder. The 100 bp + 50 bp dna ladder has a number of proprietary plasmids which are digested to completion with appropriate restriction enzymes to yield 11 bands suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Form: 10 mM Tris-HCl (pH 8.0), 1.0 mM EDTA, 50mM NaCl. Cat No: MK-2008. |  |
| 1Kb DNA Ladder II | 1Kb DNA Ladder II. The 1 kb dna ladder has a number of proprietary plasmids which are digested to completion with appropriate restriction enzymes to yield 13 bands suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Form: 10 mM Tris-HCl (pH 8.0), 1.0 mM EDTA, 50mM NaCl. Cat No: MK-2011. | |
| 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C16 | Labeled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. Group: Biochemicals. Alternative Names: [R- (Z) ]-4-Hydroxy-N, N, N-trimethyl-9-oxo-7-[[ (1-oxohexadecyl) oxy]methyl]-3, 5, 8-trioxa-4-phosphahexacos-17-en-1-aminium 4-Oxide-13C16; POPC-13C16. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C18 | Labeled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. Group: Biochemicals. Alternative Names: R- (Z) ]-4-Hydroxy-N, N, N-trimethyl-9-oxo-7-[[ (1-oxohexadecyl) oxy]methyl]-3, 5, 8-trioxa-4-phosphahexacos-17-en-1-aminium 4-Oxide-13C18; POPC-13C18. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (24S)-24,25-Epoxycholesterol | (24S)-24,25-Epoxycholesterol is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 77058-74-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences. | Worldwide |
| 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt | 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174047-40-5. Pack Sizes: 1mg. Molecular Formula: C27H45NaO5S, Molecular Weight: 504.7. US Biological Life Sciences. | Worldwide |
| 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 | 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 is the isotope labelled analog of 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt (H825760). 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H39D6NaO5S, Molecular Weight: 510.73. US Biological Life Sciences. | Worldwide |
| 3-Indolyl b-D-galactopyranoside | 3-Indolyl b-D-galactopyranoside, a synthetic substrate employed in the biomedical sector, is highly efficacious in detecting the existence of beta-galactosidase enzymes. Predominantly utilized as a marker for gene expression and screening in genetic research, this product is not intended for therapeutic purposes and cannot cure any ailment. Complex and nuanced, this substrate is an indispensable tool for conducting quality research in the field of biomedicine. Synonyms: 3-Indoxyl b-D-galactopyranoside. CAS No. 126787-65-3. Molecular formula: C14H17NO6. Mole weight: 295.29. |  |
| 4-beta-Hydroxy Cholesterol | 4-beta-Hydroxy Cholesterol is a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. It is also a potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Synonyms: (3β,4β)-Cholest-5-ene-3,4-diol; Cholest-5-ene-3β,4β-diol; 3β,4β-Dihydroxycholest-5-ene; cis-3,4-Dihydroxy-5-cholestene; cis-5-Cholestene-3,4-diol. Grades: > 95%. CAS No. 17320-10-4. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| 4-Chloro-3-indolyl b-D-galactopyranoside | 4-Chloro-3-indolyl β-D-galactopyranoside is a prominent biochemical substrate ubiquitously employed in the biomedical sector, serving as a remarkable catalyst to discern the existence of β-galactosidase activity is an indispensable marker extensively utilized in the realm of molecular biology. Notably, its versatile application aids in the comprehensive investigation of gene expression patterns and enzyme functionality across diverse biological systems. Moreover, this compound, owing to its profound impact, garners immense prominence in assays necessitating a visual representation of β-galactosidase-mediated hydrolytic processes. CAS No. 135313-63-2. Molecular formula: C14H16ClNO6. Mole weight: 329.73. | |
| 50Kb DNA Ladder | 50Kb DNA Ladder. The 50 kb dna ladder has a number of proprietary plasmids and phages dna which are digested to completion with appropriate restriction enzymes to yield 17 bands suitable for use as molecular weight standards for agarose pulsed-field gel electrophoresis (pfge). Group: Markers & Ladders. Cat No: MK-2012. | |
| Alkaline Phosphatase Mutein from Bovine, Recombinant | Part of marker enzyme portfolio. In addition to the AP Mutein, recombinant the lyophilizate contains a mixture of proteins from the Pichia system supporting the interference elimination. AP Mutein is lyophilized from a solution containing in NaCl, 0.2 mol/l; ZnCl2, 0.1 mmol/l; Tea, 30 mmol/l; MgCl2, 1 mmol/l; raffinose, 50% (w/v); pH approximately 7.6. Production is done according to the procedures of the active enzyme. Rely on the special design for reducing alkaline phosphatase-related assay interference interactions. Applications: Use alkaline phosphatase mutein (ap mutein) to eliminate human serum derived ap directed assay interferences. Group: Enzymes. Synonyms: ALKP; ALPase; Alk Phos; Alkaline phosphomonoesterase; Glycerophosphatase; Phosphomonoesterase. CAS No. 9001-78-9. ALP. Activity: <10 U/mg protein. Stability: At +2 to +8°C within specification range for 24 months. Appearance: White to yellowish lyophilizate. Source: Pichia pastoris. Species: Calf intestine. Alkaline phosphatase; ALP; ALKP; ALPase; Alk Phos; EC 3.1.3.1; Alkaline phosphomonoesterase; Glycerophosphatase; Phosphomonoesterase. Cat No: NATE-0992. | |
| AMYLOGLUCOSIDASE | AMYLOGLUCOSIDASE. Synonyms: Amyloglucosidase from Aspergillus niger;Glucoamylase, Rhizopus sp;Saccharifying enzyMe(high conversion rate);Amyloglucosidase solution from Aspergillus niger;AMG 300L;Amyloglucosidase 2D Electrophoresis marker from Aspergillus niger;Glucoamylase from Rhizopus;1,4-α-D-Glucan glucohydrolase, Exo-1,4-α-glucosidase, Glucoamylase. CAS No. 9032-08-0. Pack Sizes: 250 g. Product ID: CDF4-0038. Molecular formula: Cd+2. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; AMYLOGLUCOSIDASE; CDF4-0038; 9032-08-0; Cd+2; 232-877-2; 9032-08-0. Purity: 0.99. Color: White. EC Number: 232-877-2. Physical State: Solution. Solubility: 0.03 M sodium citrate-phosphate buffer, pH 4.5: soluble5.0mg/mL. Storage: 2-8°C. Density: ~1.2 g/mL at 25 °C. Product Description: Amyloglucosidase, a 1,4-α-D-glucan glucohydrolase, is a disaccharidase-type α-glucosidase. It is synthesized by several Aspergillus genus species. This exo-enzyme is one of the major industrial enzymes. The stability of amyloglucosidase can be increased by immobilization. |  |
| β-Galactosidase from E. coli, Recombinant (EIA Grade) | β-galactosidase, also called beta-gal or β-gal, is a hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins. Synthezise stable, highly active and reproducible ss-gal antigen and antibody conjugates. eliminate the risk of bse contamination: no animal-derived components are used in the production process. Applications: Marker enzyme for the manufacturing of antibody- and antigen-enzyme conjugates incorporated in immunoassays for colorimetric and fluorimetric detection. Group: Enzymes. Synonyms: β-galactosidase; beta-gal; β-gal; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosid. CAS No. 9031-11-2. β-gal. Mole weight: 465 kDa. Activity: > 700 U/mg protein. Stability: At -15 to -25°C within specification range for 24 months. Store under nitrogen. Appearance: White lyophilizate, stabilized with phosphate buffer and sucrose. Source: E. coli. β-galactosidase; beta-gal; β-gal; EC 3.2.1.23; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosidase; S 2107; lactozym; trilactase; β-D-galactanase; oryzatym; sumiklat; β-D-galactoside galactohydrolase; β-Galactosidase EIA Grade. Cat No: NATE-0986. | |
| Carboxypeptidase B from Porcine, Recombinant | Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis. Carboxypeptidase b (ec 3.4.17.2), also well known as protaminase, pancreatic procarboxy-peptidase b (pcpb), ... mature chain. the secreted cpb zymogen is converted to enzymatically active cpb by limited proteolysis by trypsin. Group: Enzymes. Synonyms: carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Enzyme Commission Number: EC 3.4.17.2. Purity: >90% (SDS-PAGE test). Mole weight: About 35kDa (SDS-PAGE detection). Activity: >180U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. Source: Porcine. carboxypeptidase B; protaminase; C | |
| Carboxypeptidase-B rat, Recombinant | Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis. Caspase 3 is synthesized as a 32 kda proenzyme. the active enzyme is a heterodimer of two large (17 kda) subunit...sponsible for rapidly metabolizing the c5a protein into c5a des-arg, with one less amino acid. Group: Enzymes. Synonyms: carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Enzyme Commission Number: EC 3.4.17.2. CAS No. 9025-24-5. CPB1. Activity: 50-55 units/mg protein carboxypeptidase B. Storage: -20°C. Form: Lyophilized from 20 mM Tris, pH 8.0 + 50 mM NaCl. Source: E. coli. Species: Rat. carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Cat No: NATE-0153. | |
| Creatine Kinase MM Isoenzyme Type-1 from Human, Recombinant | Creatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. Ckmt1 human recombinant without c-terminal lysine on both chains produced in pichia pastoris is a glycosylated 47kda polypeptide chain having an identical amino acid sequence compared to t...proprietary chromatographic techniques. Group: Enzymes. Synonyms: Creatine kinase M-type; EC 2.7.3.2; Creatine kinase M chain; M-CK; CKM; CKMM; CKMMITI; CKMMT1. Enzyme Commission Number: EC 2.7.3.2. Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. CK. Mole weight: 47kDa. Activity: 537 IU/mg. Stability: CKMT1 although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered colourless liquid formulation. Source: Pichia Pastoris. Species: Human. Creatine kinase M-type; EC 2.7.3.2; Creatine kinase M chain; M-CK; CKM; CKMM; CKMMITI; CKMMT1. Cat No: NATE-0820. | |
| Creatine Kinase MM Isoenzyme Type-3 from Human, Recombinant | Creatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. Ckmt3 human recombinant produced in pichia pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to mm isoenzyme in elisa.the ckmt3 is purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Creatine kin. Enzyme Commission Number: EC 2.7.3.2. Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. CK. Activity: 500 IU/mg. Stability: CKMT3 although stable at 15°C for 7 days, should be stored below -18°C. lease prevent freeze-thaw cycles. Appearance: Sterile Filtered colourless liquid formulation. Source: Pichia Pastoris. Species: Human. Creatine kinase M-type; EC 2.7.3.2; Creatine kinase M chain; M-CK; CKM; CKMM; CKMMITIII; CKMMT3. Cat No: NATE-0821. | |
| Danshensu | Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Synonyms: Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-; (αR)-α,3,4-Trihydroxybenzenepropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, (R)-; (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid; (R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid; 3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid; D-(+)-β-(3,4-Dihydroxyphenyl)lactic acid; Dan Shen Su; Dan shen suan A; DS 182; Salianic acid A; Salvianic acid A; Tanshinol. Grades: >98%. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
| EDA-ATP - ATTO-MB2 | EDA-ATP - ATTO-MB2 is a fluorescent marker molecule used to study ATP-dependent biological processes. It exhibits strong fluorescence upon binding to ATP-consuming enzymes, such as kinases and ATPases, facilitating drug development for diseases like cancer and metabolic disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-triphosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C32H41N10O15P3S (free acid). Mole weight: 930.71 (free acid). | |
| Fructosyl-Amino Acid Oxidase from Corynebacterium sp., Recombinant | Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamine oxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids. Enzyme commission (e.c.) 1.5.3.x, fructosyl amino acid oxidase [fructosyl-a-l-amino acid:oxygen oxidoreductase] is a flavoprotein that catalyzes the oxidation of fructosyl amino acids to form glucosone, amino acid and hydrogen peroxide. Applications: Fructosyl-amino acid oxidase can be used to detect the levels of glycated proteins, which are markers for diabetes mellitus. Group: Enzymes. Synonyms: Fructosyl-Amino Acid Oxidase. Fructosyl-amino acid oxidase. Mole weight: mol wt ~88 kDa by electrophoresis. Activity: > 0.45 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: E. coli. Species: Corynebacterium sp. Fructosyl-Amino Acid Oxidase. Cat No: NATE-0258. | |
| L-Lactate Dehydrogenase (Crude Enzyme) | Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion oflactate to pyruvic acid and back, as it converts NAD + to NADH and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. LDH is expressed extensively in body tissues, such as blood cells and heart muscle. Because it is released during tissue damage, it is a marker of common injuries and disease such as heart failure. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Medicine; synthesis; biotechnology; drug development. Group: Enzymes. Synonyms: lactic acid dehydrogenase; L(+)-nLDH; L-(+)-lactate dehydrogenase; L-lactic dehydrogenase; L-lactic acid dehydrogenase; lactate dehydrogenase; lactate dehydrogenase NAD-dependent; lactic dehydrogenase; NAD. Enzyme Commission Number: EC 1.1.1.27. CAS No. 9001-60-9. LDH. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. lactic acid dehydrogenase; L(+)-nLDH; L-(+)-lactate dehydrogenase; L-lactic dehydrogenase; L-lactic acid dehydrogenase; lactate dehydrogenase; lactate dehydrogenase NAD-dependent; lactic dehydrogenase; NAD-lactate dehydrogenase. Pack: 100ml. Cat No: NATE-1793. | |
| Man-9-Glc N-Glycan | Man-9-Glc N-Glycan is an essential glycan structure intricately linked to diverse biological processes assuming the role of a distinctive marker for particular enzymes and receptors. Its profound influence encompasses the facilitation of optimal protein folding and intricate cell signaling. Gaining immense significance in biomedical investigations, this product unfailingly contributes to an array of studies pertaining to protein glycosylation, glycan profiling and the identification of therapeutic targets for debilitating conditions such as cancer, alzheimer's disease and genetic anomalies. Synonyms: Oligomannose-9-Glc; Man-9-Glc; O-alpha-D-Glucopyranosyl-(1-3)-[O-alpha-D-mannopyranosyl-(1-2)]2-O-alpha-D-mannopyranosyl-(1-3)-O-[O-alpha-D-mannopyranosyl-(1-2)-O-alpha-D-mannopyranosyl-(1-3)-O-[O-alpha-D-mannopyranosyl-(1-2)-alpha-D-mannopyranosyl-(1-6)]-alpha-D-mannopyranosyl-(1-6)]-O-beta-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose. Grades: ≥95%. CAS No. 906471-35-0. Molecular formula: C76H128N2O61. Mole weight: 2045.81. | |
| N6-(6-Amino)hexyl-ATP - ATTO-633 | N6-(6-Amino)hexyl-ATP - ATTO-633 is a fluorescent nucleotide analog used in biomedical research. It acts as a fluorescent marker, enabling the visualization and tracking of ATP-dependent processes in living cells. This product plays a crucial role in studying various cellular activities, including enzyme kinetics, signal transduction and drug discovery in diseases such as cancer and neurodegenerative disorders. Synonyms: N; -(6-Amino)hexyl-adenosine-5'-triphosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3- ATTO 633 (free acid). Mole weight: 1139.35 (free acid). | |
| Native Bovine Gamma-Glutamyl Transferase | γ-glutamyl transferase is an enzyme that transfers gamma-glutamyl functional groups. It is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a prooxidant role, with regulatory effects at various levels in cellular signal transduction and cellular ...transferase; 9046-27-9; GGTP. Enzyme Commission Number: EC 2.3.2.2. CAS No. 9046-27-9. Purity: Purified. γ-GT. Activity: > 30 U/mg (Dimension Clinical Chemistry System). Appearance: Tan Powder. Storage: -20°C. Form: Lyophilized. Source: Bovine Kidney. Species: Bovine. EC 2.3.2.2; glutamyl transpeptidase; α-glutamyl transpeptidase; γ-glutamyl peptidyltransferase; γ-glutamyl transpeptidase (ambiguous); γ-GPT; γ-GT; γ-GTP; L-γ-glutamyl transpeptidase; L-γ-glutamyltransferase; L-glutamyltransferase; GGT (ambiguous); γ-glutamyltranspeptidase (ambiguous); γ-glutamyltransferase; 9046-27-9; GGTP. Cat No: NATE-0790. | |
| Native Equine γ-Glutamyltranspeptidase | γ-glutamyl transferase is an enzyme that transfers gamma-glutamyl functional groups. It is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a prooxidant role, with regulatory effects at various levels in cellular signal transduction and cellular pathophysiology. Group: Enzymes. Synonyms: EC 2.3.2.2; glutamyl transpeptidase; α-glutamyl transpeptidase; . Enzyme Commission Number: EC 2.3.2.2. CAS No. 9046-27-9. γ-GT. Activity: 5-12 units/mg solid. Storage: -20°C. Source: Equine kidney. Species: Equine. EC 2.3.2.2; glutamyl transpeptidase; α-glutamyl transpeptidase; γ-glutamyl peptidyltransferase; γ-glutamyl transpeptidase (ambiguous); γ-GPT; γ-GT; γ-GTP; L-γ-glutamyl transpeptidase; L-γ-glutamyltransferase; L-glutamyltransferase; GGT (ambiguous); γ-glutamyltranspeptidase (ambiguous); γ-glutamyltransferase; 9046-27-9; GGTP. Cat No: NATE-0791. | |
| Native Horseradish Poly Peroxidase | Native Horseradish Poly Peroxidase. Part of marker enzyme portfolio. poly peroxidase is lyophilized in 10 mmol/l potassium phosphate, 50 mmol/l nacl, 1 mmol/l edta, ph 6.1and saccharose as stabilizer. enhance elisa sensitivity by using polymeric peroxidase (poly pod). Applications: Poly peroxidase (poly pod) is a marker enzyme enabling peroxidation of reduced dyes in the indicator reaction producing a color, fluorimetric or luminescent derivative of the labeled molecule for further detection and quantification. Group: Enzymes. Synonyms: Poly Peroxidase. Peroxidase. Mole weight: 800 ± 200 kDa. Activity: >600 U/mg. Stability: At -60 to -90°C within specification range for 48 months. Appearance: Red-brown lyophilizate. Source: Horseradish. Species: Horseradish. Poly Peroxidase. Cat No: NATE-0881. | |
| Native Human Aspartate Aminotransferase | Aspartate Aminotransferase (AST), also known as Glutamate Oxaloacetate Transaminase (GOT), is a pyridoxal phosphate-dependant enzyme which exists in two isoenzymes; mitochondrial and cytosolic forms. The AST enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. In hepatic disease, serum levels are used to assess liver necrosis and for determining prognosis. In patients with acute Myocardial infarction, measurement of AST isoenzymes provides diagnostic information that differs from that obtained by determination of other marker proteins. Creative Enzymes products are not intended for use in pharmaceutical applications. Applications: Research life science elisa assay clinical chemistry. Group: Enzymes. Synonyms: EC 2.6.1.1; glutamic-oxaloacetic transaminase; glutamic-aspartic transaminase; transaminase A; AAT; AspT; 2-oxoglutaRate-glutamate aminotransferase; aspartate α-ketoglutaRate transaminase; aspartate aminotransferase; aspartate-2-oxoglutaRate transaminase; aspartic acid aminotransferas. Enzyme Commission Number: EC 2.6.1.1. CAS No. 9000-97-9. AST. Activity: >50U/ml. Storage: -20°C. Source: Human Cardiac Tissue. Species: Human. EC 2.6.1.1; glutamic-oxaloa | |
| Native Human Carboxypeptidase B | Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis. Applications: Carboxypeptidase b from creative enzymes has been used as a reference for assaying carboxypeptidase ...ino acids, to get a distinct band for each allotype during c4 electrophoresis. Group: Enzymes. Synonyms: carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Enzyme Commission Number: EC 3.4.17.2. CAS No. 9025-24-5. CPB1. Activity: 50-55 units/mg protein carboxypeptidase B. Storage: -20°C. Form: Solution in 0.05 M NaOAc pH 5.0 + 1.0 M NaCl + 0.01% NaN3. Source: Human pancreas. Species: Human. carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Cat No: NATE-0151. | |
| Native Human Creatine Kinase MB Fraction | In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes:CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes:B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form. The functional entity of the latter two mitochondrial CK isoforms is an octamer consisting of four dimers each. Applications: The mb isoenzyme of creatine kinase (mbck) can be used as a diagnostic marker for acute myocardial infarction. Group: Enzymes. Synonyms: CK-MB; CKMB; Creatine Kinase MB Fraction; Creatine Kinase MB. Purity: > 70% (SDS-PAGE). Activity: > 1,000 U/mL. Form: liquid. Source: Human heart. Species: Human. CK-MB; CKMB; Creatine Kinase MB Fraction; Creatine Kinase MB. Cat No: NATE-0141. | |
| Native Human Creatine Kinase MB/MM Mix | Creatine kinase plays a key role in the energy metabolism of cells with intermittently high and fluctuating energy requirements. Examples of such cells include cardiac or skeletal muscle cells and neural tissues of brain and retina. The enzyme catalyzes the reversible transfer of the phosphoryl group from phosphorylcreatine to ADP, in order to generate ATP. The molecular mass of the protein is found to be approximately 80 kDa. It is made up of 2 subunits, each having a molecular weight of 40 kDa ± 2000. The lighter subunit is present in larger amounts. Applications: Diagnostic controls, calibrators & standards; immunoassays; clinical chemistry; testing/assay validation; life science; cardiac markers; manufacturing. Group: Enzymes. Synonyms: Creatine Kinase MB/MM Mix; CK-MB/MM; ATP:creatine phosphotransferase; Creatine Kinase; CK; CPK; MM-CK; MB-CK; creatine phosphokinase; creatine phosphot. CAS No. 9001-15-4. CK. Activity: > 500 U/mL. Stability: 2 years. Storage: Store at -20°C. Form: Glycerol solution. Source: Human Heart. Species: Human. Creatine Kinase MB/MM Mix; CK-MB/MM; ATP:creatine phosphotransferase; Creatine Kinase; CK; CPK; MM-CK; MB-CK; creatine phosphokinase; creatine phosphotransferase; phosphocreatine kinase; adenosine triphosphate-creatine transphosphorylase; Mi-CK; CK-MM; CK-MB; CKMiMi; MiMi-CK; 9001-15-4. Cat No: NATE-0957. | |
| Native Human Creatine Kinase MM Fraction | Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Applications: May be used as a control or calibrator in monitoring myoc...stoperative cardiac medical therapy in emergency coronary artery bypass grafting for acute myocardial infarction. creatine kinase mm fraction from human heart has also been used in a study to investigate the circadian dependence of infarct size and left ventricular function after st slevation myocardial infarction. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Activity: > 200 U/mg. Form: lyophilized powder. Source: Human heart. Species: Human. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Cat No: NATE-0142. | |
| Native Human Creatine Kinase Total | Creatine kinase plays a key role in the energy metabolism of cells with intermittently high and fluctuating energy requirements. Examples of such cells include cardiac or skeletal muscle cells and neural tissues of brain and retina. The enzyme catalyzes the reversible transfer of the phosphoryl group from phosphorylcreatine to ADP, in order to generate ATP. The molecular mass of the protein is found to be approximately 80 kDa. It is made up of 2 subunits, each having a molecular weight of 40 kDa ± 2000. The lighter subunit is present in larger amounts. Applications: Diagnostic controls, calibrators & standards; immunoassays; clinical chemistry; testing/assay validation; life science; elisa; blotting; cardiac markers; manufacturing. Group: Enzymes. Synonyms: EC 2.7.3.2; ATP:creatine phosphotransferase; CK; CPK; MM-CK; MB-CK; BB-CK; creatine phosphokinase; creatine phosphotransferase; ph. Enzyme Commission Number: EC 2.7.3.2. CAS No. 9001-15-4. CK. Activity: > 5 U/mg. Stability: 3 years. Storage: Store at -20°C. Form: Lyophilized. Source: Human Heart/Brain. Species: Human. EC 2.7.3.2; ATP:creatine phosphotransferase; CK; CPK; MM-CK; MB-CK; BB-CK; creatine phosphokinase; creatine phosphotransferase; phosphocreatine kinase; adenosine triphosphate-creatine transphosphorylase; Mi-CK; CK-BB; CK-MM; CK-MB; CKMiMi; MiMi-CK; 9001-15-4. Cat No: NATE-0961. | |
| Native Human Gamma-Glutamyl Transferase | γ-glutamyl transferase is an enzyme that transfers gamma-glutamyl functional groups. It is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a prooxidant role, with regulatory effects at various levels in cellular signal transduction and cellular pathophysiology. Applications: Research life science elisa assay clinical chemistry. Group: Enzymes. Synonyms: EC 2.3.2.2; glutamyl tr. Enzyme Commission Number: EC 2.3.2.2. CAS No. 9046-27-9. γ-GT. Activity: >50 U/mg. Storage: 4°C. Source: Human Liver. Species: Human. EC 2.3.2.2; glutamyl transpeptidase; α-glutamyl transpeptidase; γ-glutamyl peptidyltransferase; γ-glutamyl transpeptidase (ambiguous); γ-GPT; γ-GT; γ-GTP; L-γ-glutamyl transpeptidase; L-γ-glutamyltransferase; L-glutamyltransferase; GGT (ambiguous); γ-glutamyltranspeptidase (ambiguous); γ-glutamyltransferase; 9046-27-9; GGTP. Cat No: NATE-0792. | |
| Native Mouse Creatine Kinase MM | Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Purity: > 90% (SDS-PAGE). CK. Mole weight: 43 kDa. Storage: Store at -20° C. Form: Liquid, 50% Glycerol, 50 mM TrisCl, 2.5 mM b-mercaptoethanol, 0.05% NaN3. Source: Mouse Skeletal Muscle. Species: Mouse. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Cat No: NATE-1887. | |
| Native Porcine Carboxypeptidase B | Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis. Protein determined by biuret. Applications: Carboxypeptidase b has been used in a study to develop a non-invasive...ith carboxypeptidase b, which is a c-terminal lysine-specific endopeptidase, is measured using flow cytometry analysis. Group: Enzymes. Synonyms: carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Enzyme Commission Number: EC 3.4.17.2. CAS No. 9025-24-5. CPB1. Storage: -20°C. Form: lyophilized powder. Contains HEPES buffer salts and carbohydrate. Source: Porcine pancreas. Species: Porcine. carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Cat No: NATE-0152. | |
| Native Porcine Creatine Kinase MM | Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Applications: Diagnostic controls, calibrators & standards; clinical chemistry; testing/assay validation; life science; manufacturing. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Purity: > 90% (SDS-PAGE). CK. Mole weight: 43 kDa. Stability: 2 years. Storage: Store at -20°C. Form: Liquid; 50% Glycerol, 50 mM TrisCl, 2.5 mM b-mercaptoethanol, 0.05% NaN3. Source: Porcine Skeletal Muscle. Species: Porcine. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Cat No: NATE-0959. | |
| Native Porcine γ-Glutamyltranspeptidase | γ-glutamyl transferase is an enzyme that transfers gamma-glutamyl functional groups. It is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a prooxidant role, with regulatory effects at various levels in cellular signal transduction and cellul...ase; GGT (ambiguous); γ-glutamyltranspeptidase (ambiguous); γ-glutamyltransferase; 9046-27-9; GGTP. Enzyme Commission Number: EC 2.3.2.2. CAS No. 9046-27-9. γ-GT. Activity: 2.0-6.0 units/mg solid. Storage: -20°C. Source: Porcine kidney. Species: Porcine. EC 2.3.2.2; glutamyl transpeptidase; α-glutamyl transpeptidase; γ-glutamyl peptidyltransferase; γ-glutamyl transpeptidase (ambiguous); γ-GPT; γ-GT; γ-GTP; L-γ-glutamyl transpeptidase; L-γ-glutamyltransferase; L-glutamyltransferase; GGT (ambiguous); γ-glutamyltranspeptidase (ambiguous); γ-glutamyltransferase; 9046-27-9; GGTP. Cat No: NATE-0793. | |
| Native Rat Creatine Kinase MM | Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Applications: Diagnostic controls, calibrators & standards; clinical chemistry; testing/assay validation; life science; manufacturing. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Purity: > 90% (SDS-PAGE). CK. Stability: 2 years. Storage: Store at -20°C. Form: Liquid in 50% Glycerol, 10mM Tris.Cl, 20mM NaCl, 0.05% NaN3. Source: Rat Skeletal Muscle. Species: Rat. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK. Cat No: NATE-0960. | |
| (+)-Neopterin | (+)-Neopterin is a precursor of tetrahydrobiopterin and can be used as a biochemical marker indicative of cell proliferation. Elevated levels of (+)-neopterin are correlated to immune system activation, malignant disease, allograft rejection, and viral infections. Additionally, (+)-neopterin serves as a cofactor for pterin in biological systems. Applications: A biochemical indicator for cellular proliferation. Group: Coenzymes. Synonyms: D-erythro-Neopterin. CAS No. 2009-64-5. Purity: ≥98%. Mole weight: 253.22. Appearance: Powder. Form: Solid. D-erythro-Neopterin; (+)-Neopterin; 2009-64-5. Cat No: COEC-061. | |
| Orotic acid | Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Carboxyuracil; Vitamin B13. CAS No. 65-86-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0157. |  |
| Orotic acid zinc | Orotic acid (zinc), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid (zinc) is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid (zinc) can induce hepatic steatosis and hepatomegaly in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Carboxyuracil zinc; Vitamin B13 zinc. CAS No. 68399-76-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0157A. | |
| Prostatic acid phosphatase from Human, recombinant | ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Group: Enzymes. Synonyms: Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Enzyme Commission Number: EC 3.1.3.2. CAS No. 9001-77-8. Purity: > 95% by SDS-PAGE. Apase. Mole weight: 41.8 kDa. Activity: >100,000 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: Baculovirus. Species: Human. Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Cat No: NATE-1673. | |
| Pro-Urokinase from Human, recombinant | Urokinase or Urokinase-type plasminogen activator (uPA) is a serine protease (EC 3.4.21.73). It is secreted as a single-chain zymogen, pro-Urokinase, possessing little or no intrinsic enzymatic activity. The single chain zymogen is converted into the active two chain enzyme (tcuPA) by cleavage of the bond between Lys157 and Ile158. After activation, Urokinase specifically cleaves the proenzyme plasminogen to form the active enzyme plasmin. The active plasmin then catalyzes the breakdown of fibrin polymers of blood clots. Urokinase is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. Additionally, it is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium. Group: Enzymes. Synonyms: Single chain Urokinase-type plasminogen activator; s. Purity: > 90% by SDS-PAGE. Pro-Urokinase. Mole weight: 49.3 kDa. Activity: >1200 mU/mg. Storage: Stable at -80°C for at least 1 year as supplied. Store reconstituted aliquots at -80°C. Avoid repeated freeze and thaw cycles. Form: Lyophilized powder. Source: E. coli. Species: Human. Single chain Urokinase-type plasminogen activator; scuPA; Urokinase-type Plasminogen Activator uPA; PLAU; Pro-Urokinase. Cat No: NATE-1689. | |
| Pyranose Oxidase from Coriolus sp., Recombinant | Pyranose oxidase (P2O) catalyzes the oxidation of aldopyranoses at position C-2 to yield the corresponding 2-ketoaldoses. P2O is a homotetrameric protein that contains covalently bound flavin adenine dinucleotide (FAD). The in vivo substrates of P2O are thought to be D-glucose, D-galactose, and D-xylose. They are oxidized to 2-keto-D-glucose (D-arabino-hexos-2-ulose, 2-dehydro-D-glucose), 2-keto-D-galactose (D-lyxo-hexos-2-ulose, 2-dehydro-D-galactose), and 2-keto-D-xylose (D-threopentos-2-ulose, 2-dehydro-D-xylose), respectively. Pyranose oxidase has significant activity with carbohydrates such as, L-sorbose, D-glucono-1,5-lactone, and D-allose. When pyranose oxidase...ults in the formation of hydrogen peroxide. Applications: Pyranose oxidase (p20) is used for the determination of d-glucose and 1,5-anhydroglucitol in clinical analysis. it is used to study the biotransformations of carbohydrates and is used as an important marker for glycemic control in diabetes patients. Group: Enzymes. Synonyms: pyranose oxidase; EC 1.1.3.10; glucose 2-oxidase; pyranose-2-oxidase; 37250-80-9; P2O. Enzyme Commission Number: EC 1.1.3.10. CAS No. 37250-80-9. P2O. Activity: > 2.7 units/mg solid. Storage: -20°C. Source: E. coli. Species: Coriolus sp. pyranose oxidase; EC 1.1.3.10; glucose 2-oxidase; pyranose-2-oxidase; 37250-80-9; P2O. Cat No: NATE-0500. | |
| Pyrimidine nucleoside phosphorylase, Recombinant | Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis. Applications: Pyrimidine nucleoside phosphorylase (pynpase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. pynpase is used to study breast cancer, specifically its role in angiogenesis. Group: Enzymes. Synonyms: Pyrimidine nucleoside phosphorylase; EC 2.4.2.2; Py-NPase; 9055-35-0; pdp (gene name); PyNPase. Enzyme Commission Number: EC 2.4.2.2. CAS No. 9055-35-0. PyNPase. Activity: > 1300 U/mL. Storage: -20°C. Source: E. coli. Pyrimidine nucleoside phosphorylase; EC 2.4.2.2; Py-NPase; 9055-35-0; pdp (gene name); PyNPase. Cat No: NATE-0646. | |
| PYZD-4409 | PYZD-4409 is an inhibitor of ubiquitin-activating enzyme UBA1 (E1). PYZD-4409 induced cell death in malignant cells and preferentially inhibited the clonogenic growth of primary acute myeloid leukemia cells compared with normal hematopoietic cells. Mechanistically, genetic or chemical inhibition of E1 increased expression of E1 stress markers. Moreover, BI-1 overexpression blocked cell death after E1 inhibition, suggesting ER stress is functionally important for cell death after E1 inhibition. Finally, in a mouse model of leukemia, intraperitoneal administration of PYZD-4409 decreased tumor weight and volume compared with control without untoward toxicity. Thus, our work highlights the E1 enzyme as a novel target for the treatment of hematologic malignancies. Synonyms: PYZD-4409; PYZD 4409; PYZD4409. Grades: 0.98. CAS No. 423148-78-1. Molecular formula: C14H7ClFN3O5. Mole weight: 351.674. | |
| (S)-(+)-Carvone | (S)-(+)-Carvone is an orally active natural product. (S)-(+)-Carvone increases the activity of antioxidant enzymes ( SOD , CAT ) and ROS , reduces the levels of oxidative stress markers ( MDA , AChE ), reduces the secretion of proinflammatory cytokines ( IL-1β , IL-4 , IL-6 , IL-10 ), and downregulates NLRP3. (S)-(+)-Carvone increases the activities of caspase -8, -9 and -3. (S)-(+)-Carvone induces apoptotic death. (S)-(+)-Carvone has antimanic-like effect, liver protection and anticancer activity against skin cancer. (S)-(+)-Carvone improves memory and arthritis [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Carvone. CAS No. 2244-16-8. Pack Sizes: 500 mg; 1 g. Product ID: HY-W013579. | |
| Succinylacetone | Succinylacetone is an inhibitor of δ-aminolevulinic acid dehydratase that inhibits heme biosynthesis. It is used as a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. Uses: Enzyme inhibitors. Synonyms: NSC 174804; NSC174804; NSC-174804; 4,6-Dioxoheptanoic acid; Succinyl acetone; Heptanoic acid, 4,6-dioxo-. CAS No. 51568-18-4. Molecular formula: C7H10O4. Mole weight: 158.153. | |
| Urokinase from Human, recombinant | Urokinase or Urokinase-type plasminogen activator (uPA) is a serine protease (EC 3.4.21.73). It is secreted as a single-chain zymogen, pro-Urokinase, possessing little or no intrinsic enzymatic activity. The single chain zymogen is converted into the active two chain enzyme (tcuPA) by cleavage of the bond between Lys157 and Ile158. After activation, Urokinase specifically cleaves the proenzyme plasminogen to form the active enzyme plasmin. The active plasmin then catalyzes the breakdown of fibrin polymers of blood clots. Urokinase is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. Additionally, it is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium. Group: Enzymes. Synonyms: Two chain urokinase-type plasminogen acti. Enzyme Commission Number: EC 3.4.21.73. Purity: > 90% by SDS-PAGE. uPA. Mole weight: 49.3 kDa. Activity: >1500 mU/mg. Storage: Stable at -80°C for at least 1 year as supplied. Store reconstituted aliquots at -80°C. Avoid repeated freeze and thaw cycles. Form: Lyophilized powder. Source: E. coli. Species: Human. Two chain urokinase-type plasminogen activator; tcuPA; PLAU; ATF; UPA; URK; u-PA; BDPLT5; QPD; Urokinase. Cat No: NATE-1690. | |
| 0.7kb DNA Marker | 0.7kb DNA Marker. 0.7kb dna marker is a premixed, ready-to-load molecular weight marker containing seven linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis, it is not recommended to be used for page. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2004. | |
| 100 bp+1.2 Kb+1.5Kb DNA Ladder | 100 bp+1.2 Kb+1.5Kb DNA Ladder. 100 bp+1.2 kb+1.5kb dna ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 100bp -1.5 kb dna fragments. the 500bp band (100 ng/5 μl) has doubled intensity than other bands to serve as reference 100bp-1500bp. . Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2006. | |
| 100 bp+1.5Kb+2Kb+3Kb DNA Ladder | 100 bp+1.5Kb+2Kb+3Kb DNA Ladder. 100 bp+1.5kb+2kb+3kb dna ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2005. | |
| 100 bp+1.5 Kb DNA Ladder | 100 bp+1.5 Kb DNA Ladder. 100 bp+1.5 kb dna ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 100bp -1.5 kb dna fragments. the 500bp band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2007. | |
| 15K DNA Marker | 15K DNA Marker. 15k dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 500 bp -15.0 kb dna fragments. the 5.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2013. | |
| 1Kb DNA Ladder I | 1Kb DNA Ladder I. 1kb dna ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 1.0 -10.0 kb dna fragments. the 4.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2010. | |
| 1Kb Plus DNA Ladder | 1Kb Plus DNA Ladder. 1kb plus dna ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 300bp -10.0 kb dna fragments. the 2.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2009. | |
| 2K DNA Marker | 2K DNA Marker. 2k dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 100 bp -2.0 kb dna fragments. the 750 bp band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. . Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2018. | |
| 2K Plus DNA Marker | 2K Plus DNA Marker. 2k plus dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 100 bp -5.0 kb dna fragments. the 750 bp band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2016. | |
| 2K Plus II DNA Marker | 2K Plus II DNA Marker. 2k plus ii dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 100 bp -8.0 kb dna fragments. the 750 bp band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2017. | |
| 5K DNA Marker | 5K DNA Marker. 5k dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 300 bp -5.0 kb dna fragments. the 1.5kb band (125 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2015. | |
| 6×DNA Loading Buffer | 6×DNA Loading Buffer. 6×dna loading buffer is used as loading buffer in nucleic acid electrophoresis. prior to loading, add appropriate volume of 6×dna loading buffer to dna sample to make its working concentration at 1×, and then load the dna samples into the gel for electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2001. | |
| 8K DNA Marker | 8K DNA Marker. 8k dna marker is a premixed, ready-to-load molecular weight marker containing six linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 500 bp -8.0 kb dna fragments. the 3.0 kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2014. | |
| Agarose | Agarose. High purity agarose which is free of dnase, rnase, and protease. staining with ethidium bromide or gel stain provides low background, strong electrophoretic separation performance, and clear bands. agarose is suitable for electrophoresis of various dna and rna. Group: Markers & Ladders. Storage: Store at room temperature for two years. Cat No: MK-2002. | |
| Gel Dye | Gel Dye. Gel dye is a sensitive, stable and relatively safe fluorescent nucleic acid dye designed to replace the highly toxic ethidium bromide (etbr) for staining dsdna, ssdna or rna in agarose gels or polyacrylamide gels. the sensitivity of gel dye is much higher than eb, and destaining is not required. gel ye and eb have virtually the same spectral properties. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2003. | |
| Lambda DNA/Bgl I | Lambda DNA/Bgl I. The bgl i digest of lambda dna yields 30 fragments suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Form: 10 mM Tris-HCl (pH 8.0), 1.0 mM EDTA. Cat No: MK-2019. | |
| Lambda DNA/Bme18 I (Ava II) | Lambda DNA/Bme18 I (Ava II). The bme18 i (ava II) digest of lambda dna yields 36 fragments suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2020. | |
| Lambda DNA/BssT1 I (Sty I) | Lambda DNA/BssT1 I (Sty I). The bsst1 i (sty i) digest of lambda dna yields 11 fragments suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2021. | |
| Lambda DNA/BstEII | Lambda DNA/BstEII. The bspeii digest of lambda dna yields 14 fragments suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2022. | |
| Lambda DNA/Hind III | Lambda DNA/Hind III. The hind iii digest of lambda dna yields 8 fragments suitable for use as molecular weight standards for agarose gel electrophoresis. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2023. | |
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