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Product | Description | |
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18-Hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoic Acid Quick inquiry Where to buy Suppliers range | 18-Hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoic Acid is produced by non-enzymatic oxidation of Eicosapentaenoic Acid (E477800). Group: Biochemicals. Grades: Highly Purified. CAS No. 141110-17-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H30O3, Molecular Weight: 318.45. US Biological Life Sciences. | Worldwide |
1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C16 Quick inquiry Where to buy Suppliers range | Labeled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. Group: Biochemicals. Alternative Names: [R- (Z) ]-4-Hydroxy-N, N, N-trimethyl-9-oxo-7-[[ (1-oxohexadecyl) oxy]methyl]-3, 5, 8-trioxa-4-phosphahexacos-17-en-1-aminium 4-Oxide-13C16; POPC-13C16. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C18 Quick inquiry Where to buy Suppliers range | Labeled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. Group: Biochemicals. Alternative Names: R- (Z) ]-4-Hydroxy-N, N, N-trimethyl-9-oxo-7-[[ (1-oxohexadecyl) oxy]methyl]-3, 5, 8-trioxa-4-phosphahexacos-17-en-1-aminium 4-Oxide-13C18; POPC-13C18. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
2,3-Lutidine-N-oxide Quick inquiry Where to buy Suppliers range | 2,3-Lutidine-N-oxide can be used in biological study of enzymic reduction of pyridine- and nitropyridine-N-oxide derivs. by ferredoxin-NADP+ oxidoreductase and the role of their electron accepting potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 22710-07-2. Pack Sizes: 250mg, 1g. Molecular Formula: C7H9NO, Molecular Weight: 123.15. US Biological Life Sciences. | Worldwide |
2',3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-(gamma-thio)-triphosphate triethylammonium salt Quick inquiry Where to buy Suppliers range | 2',3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-(gamma-thio)-triphosphate triethylammonium salt is an indispensable compound extensively applied in the field of biomedicine due to its multifaceted utility. This exceptional product serves as a fluorescent probe, facilitating comprehensive scrutiny of diverse biochemical and cellular mechanisms. Employing this compound allows for the meticulous investigation of nucleotide-binding proteins, exploration of receptor-ligand interactions, and examination of enzyme kinetics. Synonyms: [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[2-(methylamino)phenyl]carbonyloxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphinic acid; (2R, 3S, 4R, 5R) -5- (6-Amino-9H-purin-9-yl) -4-hydroxy-2- ( ( (hydroxy ( (hydroxy (thiophosphonooxy) phosphoryl) oxy) phosphoryl) oxy) methyl) tetrahydrofuran-3-yl 2-(methylamino)benzoate. CAS No. 1809315-85-2. Molecular formula: C18H23N6O13SP3·xC6H15N. Mole weight: 656.40 (free acid). | |
2'-Deoxyadenosine-15N1 N-Oxide Quick inquiry Where to buy Suppliers range | 2'-Deoxyadenosine-15N1 N-oxide is the isotope labelled analogue of 2-Deoxyadenosine N-Oxide, an adenosine analogue as potential inhibitor or substrate for adenosine kinase enzyme for the treatment of tuberculosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H13N415NO4. US Biological Life Sciences. | Worldwide |
2'-(N-Methylanthraniloyl) Guanosine 3',5'-Cyclic Monophosphate Sodium Salt Quick inquiry Where to buy Suppliers range | 2'-(N-Methylanthraniloyl) Guanosine 3',5'-Cyclic Monophosphate Sodium Salt. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 221905-46-0. IUPAC Name: sodium;[(4aR,6R,7R,7aR)-6-(2-amino-6-oxo-1H-purin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] 2-(methylamino)benzoate. Molecular formula: C18H18N6O8P.Na. Mole weight: 500.33. Catalog: APS221905460. SMILES: [Na+]. CNc1ccccc1C (=O)O[C@@H]2[C@@H]3OP (=O) ([O-])OC[C@H]3O[C@H]2n4cnc5C (=O)NC (=Nc45)N. Format: Neat. | |
30:0 Coenzyme A Ammonium salt Quick inquiry Where to buy Suppliers range | 30:0 Coenzyme A Ammonium salt is a complex biochemical compound employed for the purpose of exploring and investigating the intricate subject of fatty acid metabolism. As a catalyzing cofactor, it actively participates in the enzymatic reactions integral to the beta-oxidation of very long chain fatty acids (VLCFAs), playing a central role in the treatment of X-linked adrenoleukodystrophy (X-ALD) and Zellweger syndrome, among other related disorders. Synonyms: Triacontanoyl Coenzyme A (ammonium salt). Grades: >99%. CAS No. 2260795-81-9. Molecular formula: C51H103N10O17P3S. Mole weight: 1253.42. | |
3-Bromo-5-phenyl salicylic acid Quick inquiry Where to buy Suppliers range | The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 3-Bromo-5-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM). Synonyms: NSC 109116; 3-bromo-2-hydroxy-5-phenylbenzoic acid. Grades: ≥95%. CAS No. 4906-68-7. Molecular formula: C13H9BrO3. Mole weight: 293.1. | |
3-Bromophenylacetic Acid Quick inquiry Where to buy Suppliers range | 3-Bromophenylacetic Acid is a halo substituted phenylacetic acid with anti oxidative properties. 3-Bromophenylacetic Acid has been shown to inhibit penicillin biosynthetic enzymes. Group: Biochemicals. Alternative Names: (m-Bromophenyl)acetic Acid; 2-(3-Bromophenyl)acetic Acid; 3-Bromobenzeneacetic Acid. Grades: Highly Purified. CAS No. 1878-67-7. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
3-Chloro-L-tyrosine Quick inquiry Where to buy Suppliers range | 3-Chloro-L-tyrosine was used in the enzymatic synthesis of halogen derivatives of aromatic amino acids labeled with hydrogen isotope. 3-Chloro-L-tyrosine exhibited stronger antioxidant properties in Hb-induced oxidative stress as was evident by higher efficiency of reduction of ferryl species. Synonyms: 3-Chloro-L-Tyr-OH; 3-Chloro-4-hydroxy-L-phenylalanine; 3-Chlorotyrosine; 3-Cl-Tyr-OH; (S)-2-Amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid; (2S)-2-amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid; CLY; H-Tyr(3-Cl)-OH. Grades: ≥ 99% (HPLC). CAS No. 7423-93-0. Molecular formula: C9H10NO3Cl. Mole weight: 215.63. | |
3-Ketotrehalose Quick inquiry Where to buy Suppliers range | 3-Ketotrehalose is a 3-ketoglucosides and an oxidized product of glucoside 3-dehydrogenase. Glucoside 3-dehydrogenase is a FAD-enzyme that oxidizes glucosides and galactosides to their corresponding 3-ketoglucosides, which are reagents for detergents and polymers. Synonyms: α-D-Glucopyranosyl α-D-ribo-hexopyranosid-3-ulose. CAS No. 24885-76-5. Molecular formula: C12H20O11. Mole weight: 340.28. | |
3-(Methylamino)-propanenitrile Quick inquiry Where to buy Suppliers range | Aminoproponitriles can be used as inhibitors of oxidase enzymes and as a reagent for aminomethylphosphine ligands or the synthesis of aminobenzothiazoles. Group: Biochemicals. Alternative Names: (2-Cyanoethyl) methylamine; 3- (Methylamino) propanenitrile; 3- (Methylamino) propionitrile; 3- (N-Methylamino) propionitrile; 3- methyl aminopropiononitrile; Methyl(2-cyanoethyl)amine; N-(2-Cyanoethyl)-N-methylamine; N- (2-Cyanoethyl) methylamine; N-( β -Cyanoethyl) methylamine; N-Methyl-2-cyanoethylamine; N-Methyl-N-(2-cyanoethyl)amine; N-Methyl- β-alaninenitrile; N-Methyl- β-aminopropionitrile; NSC 8399; β - (Methylamino) propionitrile. Grades: Highly Purified. CAS No. 693-05-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
3-Nitropropionic Acid Quick inquiry Where to buy Suppliers range | A cell-permeable, irreversible inactivator (~3mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme. Disrupts the blood-brain barrier and causes severe energy (ATP) impairment. Also replicates several pathophysiological symptoms of Huntington disease, including spontaneous choreiform and dystonic movements and degeneration of striatum in rodent models. Chronic administration of 3-NP (38mg/kg/day) is shown to cause activation of c-Jun kinase in striatum. Group: Biochemicals. Alternative Names: 3-NP, 3-NPA, 3NPA. Grades: Highly Purified. CAS No. 504-88-1. Pack Sizes: 50mg. Molecular Formula: C?H?NO?. US Biological Life Sciences. | Worldwide |
4-Amino-6-mercaptopyrazolo[3,4-d]pyrimidine Quick inquiry Where to buy Suppliers range | Pyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
4-Pyridinecarbonitrile Quick inquiry Where to buy Suppliers range | A derivative of Fampridine. Fampridine is a potent convulsant. Uses: 4-cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. preparation of the antihypertensive agent pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. structure-based discovery of human l-xylulose reductase inhibitors from database screening and molecular docking. human l-xylulose reductase (xr) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes. Synonyms: pyridine-4-carbonitrile. Grades: > 95 %. CAS No. 100-48-1. Molecular formula: C6H4N2. Mole weight: 104.11. | |
5-Bromo-3-phenyl salicylic acid Quick inquiry Where to buy Suppliers range | The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 5-Bromo-3-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 140 nM) over AKR1C2 (K1 = 1.97 μM) and AKR1C3 (Ki = 21 μM). Synonyms: 5-Bromo-2-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Grades: ≥98%. CAS No. 99514-99-5. Molecular formula: C13H9BrO3. Mole weight: 293.1. | |
5-Bromo-5-nitro-1,3-dioxane Quick inquiry Where to buy Suppliers range | 5-bromo-5-nitro-1,3-Dioxane is an antimicrobial compound that is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast.1 Its mode of action occurs via the oxidation of essential protein thiols causing inhibition of enzyme activity and subsequent inhibition of microbial growth.1 This compound has been used as a preservative for biological molecules and solutions such as antibodies and antisera. Group: Biochemicals. Grades: Highly Purified. CAS No. 30007-47-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C?H?BrNO?, Molecular Weight: 212. US Biological Life Sciences. | Worldwide |
5-Hydroxymethylcytidine Quick inquiry Where to buy Suppliers range | 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. It is important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gene on and off. It was first seen in bacteriophages in 1952.[1][2] However, in 2009 it was found to be abundant in human and mouse brains,[3] as well as in embryonic stem cells.[4] In mammals, it can be generated by oxidation of 5-methylcytosine, a reaction mediated by the Tet family of enzymes. 5-Hydroxymethylcytidine is a product in DNA hydroxymethylation. The concentrations of 5-Hydroxymethylcytidine in the brain were used to study Alzheimers disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 19235-17-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
5-O-Methyl Quercetin Quick inquiry Where to buy Suppliers range | O-Methylated analogue of the flavanoid Quercertin. It is a small molecule inhibitor of NADPH Oxidase 4 enzyme. It is used in studies of flavonoid structure requirement for the increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4,7-Tetrahydroxy-5-methoxyflavone; Azaleatin; Quercetin 5-Methyl Ether. Grades: Highly Purified. CAS No. 529-51-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
6-Aminoallopurinol riboside Quick inquiry Where to buy Suppliers range | 6-Aminoallopurinol riboside is a pharmacological entity, finding application in the research of specific ailments linked to malfunctions in purine metabolism. It exerts its mode of action through the suppression of xanthine oxidase, an enzymatic catalyst in the degradation pathway of purine. Synonyms: 7-deaza-8-azaguanosine; 6-Amino-1,5-dihydro-1-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Amino-1-beta-D-ribofuranosylpyrazolo(3,4-d)pyrimidin-4-one; 6-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one. Grades: ≥95%. CAS No. 85426-74-0. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
6-Phospho-L-glucono-δ-lactone Quick inquiry Where to buy Suppliers range | 6-Phospho-L-glucono-δ-lactone is a racemic enantiomer of 6-Phosphoglucono-δ-lactone, and the other enantiomer of which is the primary oxidation product of enzyme glucose 6-phosphate oxidation. 6-Phosphoglucono-δ-lactone. It is a substrate for lactonase from Mycoplasma synoviae 53 and Mycoplasma agalactiae PG2. Molecular formula: C6H11O9P. Mole weight: 258.12. | |
6-Phospho-L-glucono-δ-lactone Quick inquiry Where to buy Suppliers range | 6-Phospho-L-glucono-δ-lactone is a racemic enantiomer of 6-Phosphoglucono-δ-lactone (P353740), itÂs other enantiomer is the primary oxidation product of enzyme glucose 6-phosphate oxidation. 6-Phosphoglucono-δ-lactone is a substrate for lactonase from Mycoplasma synoviae 53 (MS53_0025) and Mycoplasma agalactiae PG2 (MAG_6390). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C6H11O9P, Molecular Weight: 258.12. US Biological Life Sciences. | Worldwide |
(6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl Quick inquiry Where to buy Suppliers range | Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences. | Worldwide |
8-Oxo-dGDP Quick inquiry Where to buy Suppliers range | 8-Oxo-dGDP, a nucleotide analog, serves as a substrate for DNA polymerases and as a regulator for those enzymes associated with DNA repair in biochemical studies. Furthermore, it is employed to explore the involvement of oxidative stress in cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O11P2 (free acid). Mole weight: 443.20 (free acid). | |
Acaterin Quick inquiry Where to buy Suppliers range | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Synonyms: (2R)-4-[(1R)-1-hydroxyoctyl]-2-methyl-2H-furan-5-one; 3-(1-Hydroxyoctyl)-5-methyl-2(5H)-furanone. Grades: >98%. CAS No. 144398-20-9. Molecular formula: C13H22O3. Mole weight: 226.31. | |
Adrenochrome Impurity 2 Quick inquiry Where to buy Suppliers range | Adrenochrome Impurity 2 is an impurity of Adrenochrome, which was first isolated from the products of an enzymatic oxidation. CAS No. 87708-46-1. Molecular formula: C9H9NO3. Mole weight: 179.17. | |
Alcohol Oxidase, ?12 U/mg Protein Quick inquiry Where to buy Suppliers range | Alcohol Oxidase, ?12 U/mg Protein. Group: Enzymes, Inhibitors, & Substrates. CAS No. 9073-63-6. Pack Sizes: 250U. ID EBT464. | |
Aloesin Quick inquiry Where to buy Suppliers range | Aloesin is an aloe chromone that exhibits competitive inhibitory effects against tyrosinase, an enzyme responsible for catalyzing phenol oxidation in plants. Studies have shown that aloesin modulates melanogenesis and dispalys anti-inflammatory effects in rats. Synonyms: Aloe resin B; 8-b-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one. CAS No. 30861-27-9. Molecular formula: C19H22O9. Mole weight: 394.37. | |
Anacardic acid triene Quick inquiry Where to buy Suppliers range | Anacardic acid is a blanket term applied to a family of closely related compounds consisting of salicylic acid with a 15-carbon alkyl chain, which exist either in a fully saturated form or as a monoene, diene, or triene. Anacardic acid triene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid. Anacardic acid triene inhibits NADH oxidase with IC50 of 1.3 μg/ml, which is an enzyme involved in bacterial respiration. Anacardic acid triene is molluscicidal, inducing toxicity in B. glabrata (LC50 = 0.35 ppm), but is inactive against S. mansoni parasites. Synonyms: Anacardic Acid 15:3. Grades: ≥98%. CAS No. 103904-73-0. Molecular formula: C22H30O3. Mole weight: 342.47. | |
Angiotensin (1-7) Quick inquiry Where to buy Suppliers range | Angiotensin 1-7 (Ang-(1-7)) is a major active component of the renin-angiotensin system (RAS), produced from cleavage of Ang II by angiotensin-converting-enzyme type 2 (ACE2). Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity. Uses: Peptide Inhibitors. CAS No. 51833-78-4. Product ID: R1805. | |
Apatinib 25-N-Oxide Dihydrochloride Quick inquiry Where to buy Suppliers range | Apatinib 25-N-Oxide Dihydrochloride. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Pack Sizes: 5MG. Catalog: APS005784. Format: Neat. Shipping: Room Temperature. | |
Apocynin Quick inquiry Where to buy Suppliers range | An inhibitor of NADPH oxidase (an enzyme responsible for reactive oxygen species production) and is useful in the treatment of various inflammatory diseases. Group: Biochemicals. Alternative Names: 1-(4-Hydroxy-3-methoxy-phenyl)ethanone; 4-Hydroxy-3-methoxyacetophenone; 4-Acetyl-2-methoxyphenol; 4-Acetylguaiacol; 4-Hydroxy-3-methoxyphenyl Methyl Ketone; 4'-Hydroxy-3'-methoxyacetophenone; Acetoguaiacon; Acetovanillone; Apocynin; Apocynine; NSC 209524; NSC 2146. Grades: Highly Purified. CAS No. 498-02-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Betaine Quick inquiry Where to buy Suppliers range | Betaine, is the product of the enzyme oxidation of choline. It can also be used as an organic osmolytes. Betain is a methyl donor of increasingly recognized significance in biology. It can also be used for the treatment of homocystinuria which is an inherited disorder of the metabolism of amino acid methionine. Group: Biochemicals. Alternative Names: 1-Carboxy-N,N,N-trimethyl-Methanaminium Inner Salt; (Carboxymethyl) trimethylammonium Hydroxide Inner Salt; (Trimethylammonio) acetate; Abromine; Aminocoat; Aquadew AN 100; Betafin; Betafin BCR; Betafin BP; Betafin BP 20; Cystadane; Fencaijian; FinnStim; Glycine Betaine; Trimethylbetaine Glycine; Glycocoll Betaine; Glycylbetaine; Greenstim; Loramine AMB 13; Lycine; N,N,N-Trimethylglycine; Oxyneurine; Rubrine C; Trimethylbetaine; Trimethylglycocoll; α-Earleine. Grades: Highly Purified. CAS No. 107-43-7. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C?H??NO?, Molecular Weight: 117.15. US Biological Life Sciences. | Worldwide |
Betaine Aldehyde Chloride ( (Formylmethyl) trimethylammonium Chloride) Quick inquiry Where to buy Suppliers range | Intermediate in the enzymatic oxidation of choline to betaine. Group: Biochemicals. Alternative Names: (Formylmethyl) trimethylammonium Chloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
β-NADH, Reduced Disodium Salt (Nicotinamide Adenine Dinucleotide) Quick inquiry Where to buy Suppliers range | Beta-nicotinamide adenine dinucleotide hydrate. Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.NAD is a coenzyme formed from the nucleotide, nicotinamide, adenosine monophosphateand a phosphate group joining the first two components. NADP has the same structure with the addition of an extra phosphate group to AMP. NAD can be reduced to NADH during coupling with reactions which oxidize various organic substrates. For example, the reaction catalyzed by glyceraldehyde phosphate dehydrogenase during glycolysis. NADH then passes to the inside of mitochondria where it donates the electrons it is carrying to the electron transport chain. In this manner, NAD acts as an intermediate energy storage compound that indirectly generates ATP. Generally, NADP accepts electrons from catabolic reactions to form NADPH. An example is its coupling with the conversion of glucose-6-phosphate to ribose-5-phosphate in the pentose phosphate pathway. NADPH has a slightly different role to NADH in that it does not donate electrons to the electron transport chain. Instead, it tends to reduce intermediates in anabolic pathways e.g. fatty acid synthesis. NAD participates in many redox reactions in cells, including those in glycolysis and most of those in the citric acid cycle of cellular respiration. Nicotinamide adenine dinucleotide (NAD) and its relative nicotinamide adenine dinucleotide phosphate (NADP) are two of the most important coenzymes in the cell. In cells, most oxidations are accomplished by the removal of hydrogen atoms. Both of these coenzymes play crucial roles in this. Each molecule of NAD+ (or NADP+) can acquire two electrons; that is, be reduced by two electrons. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium. Group: Biochemicals. Alternative Names: β-DPNH; β-NADH; DPNH; Diphosphopyridine nucleotide, reduced form; NADH. Grades: Highly Purified. CAS No. 606-68-8. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C21H27N7O14P2Na2, Molecular Weight: 709.41. US Biological Life Sciences. | Worldwide |
β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate Quick inquiry Where to buy Suppliers range | β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(Trihydrogen Diphosphate), P'?5'-Ester with 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium Hydroxide Sodium Salt Hydrate; Adenine-nicotinamide Dinucleotide Sodium Salt Hydrate; CO-I Sodium Salt Hydrate; Codehydrase I Sodium Salt Hydrate; Codehydrogenase I Sodium Salt Hydrate; Coenzyme I Sodium Salt Hydrate; Cozymase I Sodium Salt Hydrate; DPN Sodium Salt Hydrate; Diphosphopyridine Nucleotide Sodium Salt Hydrate; Enzopride Sodium Salt Hydrate; NAD Sodium Salt Hydrate; NAD+ Sodium Salt Hydrate; NSC 20272 Sodium Salt Hydrate; Nadide Sodium Salt Hydrate; Nicotinamide-adenine Dinucleotide Sodium Salt Hydrate; Oxidized diphosphopyridine Nucleotide Sodium Salt Hydrate; β-Diphosphopyridine Nucleotide Sodium Salt Hydrate; β-NAD Sodium Salt Hydrate; β-NAD+ Sodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7NaO14P2 X(H2O). Mole weight: 685.41. | |
BIBB 515 Quick inquiry Where to buy Suppliers range | 2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. It is concluded that the lipid-lowering effect of BIBB 515 is mainly the result of an inhibition of LDL production rather than due to an increase in LDL catabolism. OSC inhibitors may offer a novel approach for lipid-lowering therapy. Synonyms: BIBB-515; BIBB515. Grades: ≥98%. CAS No. 156635-05-1. Molecular formula: C22H21ClN2O2. Mole weight: 380.9. | |
Bizine Quick inquiry Where to buy Suppliers range | Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme, which can oxidatively cleave methyl groups from monomethyl and dimethyl Lys4 of histone H3. Bizine is an LSD1 inhibitor, which is a phenelzine analog that inhibits lysine-specific demethylase 1 with ki of 59 nM. It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Synonyms: BSM-0353. Grades: ≥95%. CAS No. 1591932-50-1. Molecular formula: C18H23N3O. Mole weight: 297.4. | |
Bosutinib N-Oxide Quick inquiry Where to buy Suppliers range | Bosutinib N-Oxide. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates; Impurity Standards. Catalog: APS001041. Format: Neat. Product Type: Impurity. | |
Catalase, Laboratory Grade, 1 mL Quick inquiry Where to buy Suppliers range | Dilute 1 mL catalase to 715 mL with distilled water for a final concentration of 400 IU/mL; converts hydrogen peroxide to oxygen and water; keep refrigerated; oxidizing enzyme. This product has a shelf life of 6 months from date of receipt. Health Risk: 1. Flammability: 1. Reactivity: 0. Grades: chem-grade laboratory. CAS No. 9001-5-2. Product ID: 853530. -- SOLD FOR EDUCATIONAL USE ONLY -- | |
Catalase, Laboratory Grade, 5 mL Quick inquiry Where to buy Suppliers range | Dilute 1 mL catalase to 715 mL with distilled water for a final concentration of 400 IU/mL; converts hydrogen peroxide to oxygen and water; keep refrigerated; oxidizing enzyme. This product has a shelf life of 6 months from date of receipt. Health Risk: 1. Flammability: 1. Reactivity: 0. Grades: chem-grade laboratory. CAS No. 9001-5-2. Product ID: 853532. -- SOLD FOR EDUCATIONAL USE ONLY -- | |
CAY10485 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
CAY10486 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
Cerulenin (Helicocerin, NSC 116069, 2,3-Epoxy-4-oxo-7,10-dodecadienamide) Quick inquiry Where to buy Suppliers range | Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens and identified as an antifungal in the 1960s. Over the past 40 years cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to B-keto-acyl-ACP synthase blocking the interaction of malonyl CoA. Cerulenin is also an inhibitor of bacterial fatty acid synthesis acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 17397-89-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Cinnamylamine Hydrochloride Quick inquiry Where to buy Suppliers range | Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 5586-89-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C9H12ClN, Molecular Weight: 169.65. US Biological Life Sciences. | Worldwide |
Coelenterazine Quick inquiry Where to buy Suppliers range | Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.1 The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum, 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green or yellow fluorescent protein, in bioluminescent resonance energy transfer studies.2,3 Alternatively, the calcium-mediated release of coelenterazine from aequorin, followed by non-enzymatic oxidation of this compound, results in bioluminescence. As light emission depends on both calcium and cellular redox status, this reaction is used to non-fluorescently detect changes in calcium level and redox status.4,5. Group: Biochemicals. Alternative Names: 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one; CLZN; Preluciferin; Luciferin; 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one. Grades: Highly Purified. CAS No. 55779-48-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 423.46. US Biological Life Sciences. | Worldwide |
Coenzyme A Quick inquiry Where to buy Suppliers range | Coenzyme A is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. Coenzyme A plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. About 4% of cellular enzymes utilize CoA as a substrate. Synonyms: CoASH; Coenzyme A (free acid); Depot-Zeel; Coenzyme ASH; 3'-phosphoadenosine 5'-{3-[ (3R) -3-hydroxy-2, 2-dimethyl-4-oxo-4- ({3-oxo-3-[ (2-sulfanylethyl) amino]propyl}amino) butyl] dihydrogen diphosphate}. Grades: >85%. CAS No. 85-61-0. Molecular formula: C21H36N7O16P3S. Mole weight: 767.53. | |
Cranberry Puree Quick inquiry Where to buy Suppliers range | Cranberry Puree is natural, unprocessed and undiluted fruit mash. It contains various natural enzymes that induce mild skin exfoliation. Rich in Polyphenols (catechin, quercitin and myricetin) found in cranberries helping with skin issues and restore elasticity to aging skin. Contains a very high essential fatty acid profile, along with a good mix of tocopherols and tocotrienols (vitamin E) content, high phytosterols and a 1:1 ratio of omega 3 to omega 6 essential fatty acids which give it excellent anti-oxidant activity and skin nurturing benefits. Uses: Mild exfoliating treatments, face masks, facial treatments, facial cleansers, creams, moisturizers, lotions and serums. Group: Skin Actives. CAS No. 91770-88-6. Product ID: ACM91770886-2. Appearance: Vibrant red to dull reddish brown, liquid semi-viscous. | |
Decapeptide-12 Quick inquiry Where to buy Suppliers range | Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. Synonyms: L-Tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-L-tyrosine. Grades: 98%. CAS No. 137665-91-9. Molecular formula: C65H90N18O17. Mole weight: 1395.5. | |
D-Glucose-6-phosphate barium salt hydrate Quick inquiry Where to buy Suppliers range | D-Glucose-6-phosphate barium salt hydrate, a biochemical reagent prevalent in the biomedicine industry, finds extensive use as an inhibitor of glucose-6-phosphate dehydrogenase. This pivotal enzyme of the pentose phosphate pathway warrants careful investigation of its role in metabolic disorders. In addition, this agent's unique property of studying oxidative stress on living cells makes it an excellent resource for exploring diverse avenues of biomedical research. Synonyms: Robison Ester Barium Salt. CAS No. 150400-00-3. Molecular formula: C6H11BaO9P xH2O. Mole weight: 395.45 (anydrous basis). | |
D-Valine, 99+% Quick inquiry Where to buy Suppliers range | D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats. Group: Biochemicals. Alternative Names: D-Val-OH; (-)-2-Amino-3-methylbutyric Acid; (R)-3-Methyl-2-aminobutanoic Acid; (R)-Valine; D-(-)-Valine; NSC 20654. Grades: Highly Purified. CAS No. 640-68-6. Pack Sizes: 5g, 25g, 100g, 250g, 500g. Molecular Formula: C5H11NO2, Molecular Weight: 117.1. US Biological Life Sciences. | Worldwide |
Ebselen Quick inquiry Where to buy Suppliers range | Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Synonyms: SPI-1005; SPI1005; SPI 1005; Ebselen; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305. Grades: >98%. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.192. | |
ERO1 Inhibitor II, EN460 Quick inquiry Where to buy Suppliers range | A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1alpha and inhibits its activity (IC50 = 1.9uM). Also prevents ERO1 re-oxidation both in vitro and in mouse embryonic fibroblasts. Activates the unfolded protein response and protects ER-stressed 293T cells. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. EN460 binding to ERO1alpha is shown to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme. Its inhibitory action appears to be irreversible, however addition of FAD and tris (hydroxypropyl) phosphine can restore some enzyme activity. Group: Biochemicals. Alternative Names: (Z)-2-Chloro-5-(4,5-dihydro-5-oxo-4-((5-phenyl-2-furanyl)methylene)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzoic Acid, (Z)-2-Chloro-5-(5-oxo-4-((5-phenylfuran-2-yl)methylene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic Acid. Grades: Highly Purified. CAS No. 496807-64-8. Pack Sizes: 25mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 460.8. US Biological Life Sciences. | Worldwide |
Ethyl 2,3-di-O-benzyl-4,6-O-benzylidene-a-D-thiomannopyranoside S-oxide Quick inquiry Where to buy Suppliers range | Ethyl 2,3-di-O-benzyl-4,6-O-benzylidene-a-D-thiomannopyranoside S-oxide is a crucial compound employed in biomedicine. With its unique structure, it plays a vital role in the development of new drugs for the treatment of various diseases. This compound exhibits promising potential in targeting specific enzymes and receptors associated with certain diseases, aiding in the exploration of novel therapeutic interventions. Synonyms: 2,3-Di-O-benzyl-4,6-O-benzylidene 1-deoxy-1-(ethylsulfinyl)-a-D-mannopyranose. CAS No. 188357-34-8. Molecular formula: C29H32O6S. Mole weight: 508.63. | |
Ethyl 3-Methyl-2-butenoate Quick inquiry Where to buy Suppliers range | Ethyl 3-Methyl-2-butenoate is used in the synthesis of Endothelin-A antagonist ABT-546 used in the preparation of antidepressant Rolipram. Also used in the synthesis of potent inhibitors of human inducible nitric oxide synthases, important enzymes in cellular signaling. Group: Biochemicals. Alternative Names: 3-Methyl-2-butenoic Acid Ethyl Ester; 3-Methyl-2-butenoic Acid Ethyl Ester; Ethyl 3,3-Dimethylacrylate; Ethyl 3-Methyl-2-butenoate; Ethyl 3-Methylcrotonate; Ethyl Dimethylacrylate; Ethyl Isobutenoate; Ethyl Isopropylideneacetate; Ethyl Senecioate; Ethyl β, β-Dimethylacrylate; Ethyl β-Methylcrotonate; NSC 61853; NSC 99208. Grades: Highly Purified. CAS No. 638-10-8. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
Frenatin 3 Quick inquiry Where to buy Suppliers range | Frenatin 3 inhibits the production of nitric oxide by the enzyme neuronal nitric oxide synthase at a micromolar concentration by binding to its regulatory protein, Ca2+ calmodulin, a protein known to recognize and bind amphipathic alpha-helices. Grades: >95% by HPLC. Molecular formula: C88H146N24O24S. Mole weight: 1956.31. | |
Galanthamine N-Oxide Quick inquiry Where to buy Suppliers range | Galanthamine N-Oxide. Uses: For analytical and research use. Group: Chiral Molecules; Enzyme Activators, Inhibitors & Substrates. Alternative Names: Galanthamine, 10-oxide, (10β)-,6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 11-oxide, (4aS,6R,8aS,11R)-, Galanthamine N-oxide, Galanthamine β-N-oxide. CAS No. 134332-50-6. Molecular formula: C17H21NO4. Mole weight: 303.35. Catalog: APS134332506. SMILES: COc1ccc2C[N@+](C)([O-])CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24. Format: Neat. | |
Graphene Oxide Solution Quick inquiry Where to buy Suppliers range | Graphene Oxide Solution. Uses: ?Functional composite materials (fabric reinforcement, hybrid scaffold for tissue engineering, barrier for electromagnetic waves); ?Biomedical & bio-imaging applications (drug delivery carrier, imaging probe, biosensor, photo-thermal therapy, enzyme activation catalyst); ?Energy conversion & storage system (battery & supercapacitor); ?Catalyst for chemical reactions; ?Filter membrane for waste water treatment. Product ID: ACMA00020896. Appearance: Dried powder. | |
Horseradish peroxidase Quick inquiry Where to buy Suppliers range | Peroxidase is a heme-containing enzyme, and it can be used to oxidize a wide variety of substrates. Synonyms: HRP; Peroxidase. CAS No. 9003-99-0. Molecular formula: H2O3. | |
Hydroxyapatite Nanoparticles Dispersion (Ca5(OH)(PO4)3]x, Diameter:80-100nm, 99.9%) Quick inquiry Where to buy Suppliers range | Calcium phosphate is a natural biomaterial with good biocompatibility and degradability, and has broad application prospects in biomedical fields such as tissue repair, drug delivery, gene transfection, and diagnostic imaging. people's attention. Due to its similarity in chemical composition and biological properties with the inorganic phase of vertebrate bone, it is widely used as a bone tissue substitute material, and its safety has been proved by a large number of experiments and clinical applications. In addition, calcium phosphate maintains high stability at physiological pH, but can rapidly dissociate in the acidic environment of endosomes (pH 5.0~6.0) or lysosomes (pH 4.0~5.0), by changing endosome/lysosomes. The osmotic pressure of the enzyme body breaks the ring, thereby releasing the loaded drug into the cytoplasm. Uses: ·Bone Repair/Tissue Engineering ·Drug/Gene Delivery ·Protein adsorption ·Bioimaging. Group: Metal Oxide Colloids. CAS No. 12167-74-7. Molecular Weight: 1004.67 g/mol. InChIKey: 158 °C at 760 mmHg. Boiling Point: 1100 °C (lit.). Flash Point: 99.9 %. Purity: 1.038 g/mL at 25°C. | |
Itopride N-Oxide Quick inquiry Where to buy Suppliers range | Itopride N-Oxide. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 141996-98-7. IUPAC Name: 2-[4-[[ (3, 4-dimethoxybenzoyl) amino]methyl]phenoxy]-N, N-dimethylethanamine oxide. Molecular formula: C20H26N2O5. Mole weight: 374.43. Catalog: APS141996987. SMILES: COc1ccc (cc1OC)C (=O)NCc2ccc (OCC[N+] (C) (C)[O-])cc2. Format: Neat. | |
Leuco-adrenochrome Quick inquiry Where to buy Suppliers range | Leuco-adrenochrome is an impurity of Adrenochrome, which was first isolated from the products of an enzymatic oxidation. Synonyms: (S)-1-methylindoline-3,5,6-triol. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
L-Hexuron Quick inquiry Where to buy Suppliers range | L-Hexuron is a superior vitamin C derivative. It is very stable, and is easily converted to the active form by enzymes in the skin. Uses: Skin lightening, Collagen stimulation, Anti-oxidant. Group: Skin Care Active Ingredients. INCI Name: 3-O-Ethyl-L-Ascorbic Acid. CAS Number: 86404-04-8. | United States and all of its trading partners.. |
L+Lactic Acid, Calcium Salt, Pentahydrate Quick inquiry Where to buy Suppliers range | Lactic acid (2-hydroxypropanoic acid), also known as milk acid, is a chemical compound that plays a role in several biochemical processes. It was first isolated in 1780 by a Swedish chemist, Carl Wilhelm Scheele, and is a carboxylic acid with a chemical formula of C3H6O3. It has a hydroxyl group adjacent to the carboxyl group, making it an alpha hydroxy acid (AHA). In solution, it can lose a proton from the acidic group, producing the lactate ion CH3CH(OH)COO?. It is miscible with water or ethanol, and is hygroscopic. Lactic acid is chiral and has two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-(-)-lactic acid or (R)-lactic acid. L-(+)-Lactic acid is the biologically important isomer.In animals, L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal which is governed by a number of factors including: monocarboxylate transporters, concentration and isoform of LDH and oxidative capacity of tissues. The concentration of blood lactate is usually 1-2 mmol/L at rest, but can rise to over 20 mmol/L during intense exertion. Industrially, lactic acid fermentation is performed by Lactobacillus bacteria, among others. These bacteria can operate in the mouth; the acid they produce is responsible for the tooth decay known as caries.In medicine, lactate is one of the main components of Ringer's lactate or lactated Ringer's solution (Compound Sodium Lactate or Hartmann's Solution in the UK). This intravenous fluid consists of sodium and potassium cations, with lactate and chloride anions, in solution with distilled water in concentration so as to be isotonic compared to human blood. It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or a burn injury. Group: Biochemicals. Alternative Names: Lactic Acid Calcium Salt (2:1) Pentahydrate; Propanoic Acid 2-Hydroxycalcium Salt Pentahydrate; Calcium Lactate Pentahydrate; Puracal DC. Grades: USP. CAS No. 5743-47-5. Pack Sizes: 100g, 250g, 500g, 1Kg, 2.5Kg. Molecular Formula: C6H10O6 Ca 5H2O, Molecular Weight: 308.29. US Biological Life Sciences. | Worldwide |
LX2343 Quick inquiry Where to buy Suppliers range | LX2343 is an inhibitor of β-site amyloid protein cleaving enzyme 1 (BACE1/β-secretase) with IC50 = 11.43 μM. It also acts as a non-ATP competitive PI3K inhibitor (IC50 = 15.99 μM). LX2343 was shown to ameliorate the cognitive dysfunction of AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy. Synonyms: LX-2343; LX 2343; 2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide. Grades: ≥98%. CAS No. 333745-53-2. Molecular formula: C22H19ClN2O6S. Mole weight: 474.91. | |
N-[4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine N-Oxide Quick inquiry Where to buy Suppliers range | N-[4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine N-Oxide. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates; Impurity Standards. Pack Sizes: 5MG. Catalog: APS010186. Format: Neat. Product Type: Impurity. Shipping: Room Temperature. | |
N-(4-piperazinyl)-oxide ABT 199 Quick inquiry Where to buy Suppliers range | N-(4-piperazinyl)-oxide ABT 199. Uses: For analytical and research use. Group: Chiral Molecules; Enzyme Activators, Inhibitors & Substrates. Catalog: APS002404. Format: Neat. | |
N5-(1-Iminoethyl)-L-ornithine Dihydrochloride Quick inquiry Where to buy Suppliers range | N5-(1-Iminoethyl)-L-ornithine Dihydrochloride is an inhibitor of nitric oxide synthase (NOS), an enzyme that catalyzes the conversion of L-arginine to L-citrulline and nitric oxide. It also improves cardiac function and microcirculation. N5-(1-Iminoethyl)-L-ornithine Dihydrochloride inhibits inducible NOS (iNOS). These enzymes play critical roles in a wide array of physiological and pathophysiological conditions such as blood pressure regulation, inflammation, and infection. Group: Biochemicals. Grades: Highly Purified. CAS No. 159190-44-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C7H15N3O2 2HCl, Molecular Weight: 173.217291999999. US Biological Life Sciences. | Worldwide |
NADH Thio, Reduced (Nicotinamide Adenine Dinucleotide), Thio-NADH) Quick inquiry Where to buy Suppliers range | Beta-nicotinamide adenine dinucleotide hydrate. Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.NAD is a coenzyme formed from the nucleotide, nicotinamide, adenosine monophosphateand a phosphate group joining the first two components. NADP has the same structure with the addition of an extra phosphate group to AMP. NAD can be reduced to NADH during coupling with reactions which oxidize various organic substrates. For example, the reaction catalyzed by glyceraldehyde phosphate dehydrogenase during glycolysis. NADH then passes to the inside of mitochondria where it donates the electrons it is carrying to the electron transport chain. In this manner, NAD acts as an intermediate energy storage compound that indirectly generates ATP. Generally, NADP accepts electrons from catabolic reactions to form NADPH. An example is its coupling with the conversion of glucose-6-phosphate to ribose-5-phosphate in the pentose phosphate pathway. NADPH has a slightly different role to NADH in that it does not donate electrons to the electron transport chain. Instead, it tends to reduce intermediates in anabolic pathways e.g. fatty acid synthesis. NAD participates in many redox reactions in cells, including those in glycolysis and most of those in the citric acid cycle of cellular respiration. Nicotinamide adenine dinucleotide (NAD) and its relative nicotinamide adenine dinucleotide phosphate (NADP) are two of the most important coenzymes in the cell. In cells, most oxidations are accomplished by the removal of hydrogen atoms. Both of these coenzymes play crucial roles in this. Each molecule of NAD+ (or NADP+) can acquire two electrons; that is, be reduced by two electrons. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium. For NAD, the reaction is thus:NAD+ + 2H -> NADH + H+. Group: Biochemicals. Alternative Names: Nicotinamide Adenine Dinucleotide; Thio-NADH; Thionicotinamide adenine dinucleotide. Grades: Highly Purified. CAS No. 1921-48-8. Pack Sizes: 100mg. Molecular Formula: C21H29N7O13SP2, Molecular Weight: 681.51. US Biological Life Sciences. | Worldwide |