Enzyme With Thiol Suppliers USA
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Product | Description | |
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2,3,4,6-Tetra-O-benzyl-5-thio-D-glucono-1,5-lactone Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-benzyl-5-thio-D-glucono-1,5-lactone, a bioactive compound utilized in the pharmaceutical industry, serves as a crucial substrate for the production of novel potent antibacterial or antiviral agents. Aside from its primary function, this biochemical can also function as an important intermediate in the generation of inhibitors of carbohydrate-processing enzymes that can potentially treat metabolic disorders such as diabetes, obesity, and cancer. Synonyms: 3,4,5-Tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-thiopyran-2-one; 2,3,4,6-tetra-o-benzyl-5-thio-d-glucono-1,5-lactone; 3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)thian-2-one; D-Gluconic acid, 2,3,4,6-tetrakis-O-(phenylmethyl)-5-thio-, d-thiolactone; BCP29940; CS-0444454. CAS No. 131757-92-1. Molecular formula: C34H34O5S. Mole weight: 554.70. | |
2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a biomedically significant reagent used to investigate the intricate mechanisms of DNA synthesis and repair. As a non-hydrolyzable analog of adenosine triphosphate (ATP), it is implicated in inhibiting the activity of reverse transcriptase - a vital aspect of HIV/AIDS treatment. With its remarkable affinity and specificity towards RNA polymerase and other enzymes central to DNA metabolism, this powerful tool is a prized asset for researchers in the biomedical field. Synonyms: Alpha Thiol ddATP; 1-Thio-ddATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O10P3S. Mole weight: 491.20. | |
2',3'-Dideoxycytidine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 2',3'-Dideoxycytidine-5'-O-(1-Thiotriphosphate), often referred to as ddCTP, is a crucial analog used in the biomedical field. This potent inhibitor of reverse transcriptase has been lauded for its effectiveness in hindering viral replication. Specifically, ddCTP is frequently utilized in the treatment of HIV and AIDS due to its ability to stop the reverse transcriptase enzyme from catalyzing the formation of DNA from RNA. Synonyms: Alpha Thiol ddCTP; 1-Thio-ddCTP. Grades: ≥90% by AX-HPLC. Molecular formula: C9H16N3O11P3S. Mole weight: 467.23. | |
2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine Quick inquiry Where to buy Suppliers range | 2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine, a robust medication utilized in the treatment of various cancers spanning from pancreatic, breast, to colon cancer, ameliorates the condition by hindering DNA synthesis through the suppression of the enzyme ribonucleotide reductase. Furthermore, its multifaceted properties suggest it as an attractive immunosuppressant for tackling autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-; 2'-Deoxy-2'-fluoro-4'-thio-β-D-arabinouridine; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 941610-00-0. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
2'-Deoxyadenosine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 2'-Deoxyadenosine-5'-O-(1-Thiotriphosphate) - a specialized nucleotide - is typically employed in biochemical assays that evaluate the functioning of enzymes, including kinases and GTPases. Its inclusion in such assays is aimed at exploring the intricate mechanics of protein phosphorylation and nucleotide exchange in the aforementioned enzymes. Synonyms: Alpha Thiol dATP; 1-Thio-dATP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O11P3S. Mole weight: 507.25. | |
2'-Deoxycytidine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 2'-Deoxycytidine-5'-O-(1-Thiotriphosphate) - a prime asset within the domain of pharmaceutical research. This compound is amply exploited in enzymatic assays, aimed at comprehending the intricacies of DNA-dependent RNA and DNA polymerases during both replication and transcription. Its merit notably extends towards the development of antiviral medications targeted at ameliorating the progression of viral infections inclusive of HIV. Synonyms: Alpha Thiol dCTP; 1-Thio-dCTP; alpha-Phosphorothioate-modified dctp. Grades: ≥95% by AX-HPLC. Molecular formula: C9H16N3O12P3S. Mole weight: 483.23. | |
3'-Azido-2',3'-dideoxythymidine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 3'-Azido-2',3'-dideoxythymidine-5'-O-(1-Thiotriphosphate) is a potent antiviral nucleotide analog, inhibiting reverse transcriptase enzymes that is essential in the reserch of HIV and AIDS. Acting as a chain terminator, it prevents the replication of the viral genome, reducing viral load and inhibiting disease progression. Synonyms: Alpha Thiol-2',3'-Azido-ddTTP; 1-Thio-2',3'-Azido-ddTTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O12P3S. Mole weight: 523.25. | |
3'-Deoxythymidine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | 3'-Deoxythymidine-5'-O-(1-Thiotriphosphate) is a crucial compound used in the biomedical industry for the research and development of nucleic acids during molecular biology studies. It acts as a substrate in enzymatic reactions, facilitating DNA polymerization and gene expression. This compound is extensively utilized in the research of viral diseases like HIV, where it exhibiting potent antiviral properties. Synonyms: Alpha Thiol ddTTP; 1-Thio-ddTTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H17N2O12P3S. Mole weight: 482.20. | |
4-Arm PEG-DBCO Quick inquiry Where to buy Suppliers range | DBCO has very high reaction selectivity toward azide, enabling its use in modifying biomolecules including peptide, protein, enzyme, live cells, whole organisms etc. At physiological temperature and pH ranges, the DBCO group does not react with amine or hydroxyl, and DBCO also reacts with the azide group much faster than with free thiol groups. Group: Functional PEGs. Alternative Names: DBCO Azide Click PEG. Product ID: ACMA00006093. Appearance: White/Off-white solid or viscous liquid depends on molecular weight. Storage: -20?,protected from light and moisture. | |
4-Methylphenyl b-D-thioglucopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylphenyl b-D-thioglucopyranoside is a crucial compound extensively used in the biomedical industry. It is commonly employed as a substrate in enzymatic assays, aiding in the study of enzyme kinetics and sugar metabolism. Furthermore, it proves valuable in the diagnosis and research of various diseases, particularly those related to abnormal carbohydrate metabolism. Synonyms: 4-Methylphenyl 1-thio-beta-D-glucopyranoside; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(p-tolylthio)tetrahydro-2H-pyran-3,4,5-triol; (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyloxane-3,4,5-triol; Phenyl 1-thiol-alpha-D-mannopyranoside; SCHEMBL3322973; DTXSID50564228; p-Tolyl beta-D-thioglucopyranoside; p-Tolyl 1-thio- beta -D-glucopyranoside; 4-Methylphenyl 1-thio-b-D-glucopyranoside; p-Tolyl 1-thio-beta-D-glucopyranoside, 99%; beta-D-Glucopyranoside, 4-methylphenyl 1-thio-; W-200879. CAS No. 1152-39-2. Molecular formula: C13H18O5S. Mole weight: 286.35. | |
4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose Quick inquiry Where to buy Suppliers range | 4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose is an exemplary compound, manifesting unparalleled efficacy in research of an extensive array of ailments, encompassing the formidable spectrums of diabetes and cancer. This extraordinary entity, captivating the realm of glycobiology and carbohydrate chemistry, operates as an indomitable antagonist against glycosidase enzymes. Synonyms: b-D-Thiolactose. Molecular formula: C12H22O10S. Mole weight: 358.36. | |
4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose Quick inquiry Where to buy Suppliers range | 4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose, a compound of utmost importance in the biomedical industry, has garnered significant attention due to its potential implications in the research of diabetes and associated metabolic ailments. Serving as an compound for reducing glucose levels, this compound adeptly modulates the regulation of blood sugar. Its unparalleled structure facilitates precise interactions with enzymes involved in glucose metabolism. Synonyms: Cellobiose thiol. Molecular formula: C12H22O10S. Mole weight: 358.36. | |
5-Bromo-5-nitro-1,3-dioxane Quick inquiry Where to buy Suppliers range | 5-bromo-5-nitro-1,3-Dioxane is an antimicrobial compound that is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast.1 Its mode of action occurs via the oxidation of essential protein thiols causing inhibition of enzyme activity and subsequent inhibition of microbial growth.1 This compound has been used as a preservative for biological molecules and solutions such as antibodies and antisera. Group: Biochemicals. Grades: Highly Purified. CAS No. 30007-47-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C?H?BrNO?, Molecular Weight: 212. US Biological Life Sciences. | Worldwide |
7-Azido-4-methylcoumarin (AzMC) Quick inquiry Where to buy Suppliers range | Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4- methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex=365nm and lambdaem=450nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25mM should be avoided for maximum efficiency. Group: Biochemicals. Grades: Highly Purified. CAS No. 95633-27-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Adenosine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | Adenosine-5'-O-(1-Thiotriphosphate) - this nucleotide analog, frequently used in biochemical research to investigate ATP-utilizing enzymes, shows promise in treating cancer and neurological maladies by inhibiting particular biological enzyme activity. Additionally, it can assess the effect of drugs on the ATPase activity of proteins, making it a valuable tool in pharmacology. Synonyms: Alpha Thiol ATP; 1-Thio-ATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O12P3S. Mole weight: 523.25. | |
Boc-2-aminoindane-2-carboxylic acid Quick inquiry Where to buy Suppliers range | Boc-2-aminoindane-2-carboxylic acid is used to prepare thiol dipeptides as dual inhibitors of angiotensin-I-converting enzyme and neutral endopeptidase. It is also used in the synthesis of bombesin analogs. Synonyms: Boc-Aic-OH; 2-((tert-Butoxycarbonyl)amino)-2,3-dihydro-1H-indene-2-carboxylic acid; N-BOC-2-AMINOINDANE-2-CARBOXYLIC ACID; 2-(BOC-AMINO)INDANE-2-CARBOXYLIC ACID; 2-[(tert-butoxy)carbonylamino]indane-2-carboxylic acid; BOC AIC OH. Grades: ≥ 98% (HPLC). CAS No. 71066-00-7. Molecular formula: C15H19NO4. Mole weight: 277.32. | |
CAY10485 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
CAY10486 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
Cytidine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | Cytidine-5'-O-(1-Thiotriphosphate) is a crucial reagent extensively employed in the biomedicine sector. It is widely used in the field of molecular biology for studying cellular processes like RNA synthesis and protein translation. Additionally, this compound is utilized in research focused on the analysis of nucleotide sequences and studying the role of RNA enzymes. Synonyms: Alpha Thiol CTP; 1-Thio-CTP. Grades: ≥90% by AX-HPLC. CAS No. 118353-34-7. Molecular formula: C9H12N3Na4O13P3S. Mole weight: 587.15. | |
ERO1 Inhibitor II, EN460 Quick inquiry Where to buy Suppliers range | A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1alpha and inhibits its activity (IC50 = 1.9uM). Also prevents ERO1 re-oxidation both in vitro and in mouse embryonic fibroblasts. Activates the unfolded protein response and protects ER-stressed 293T cells. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. EN460 binding to ERO1alpha is shown to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme. Its inhibitory action appears to be irreversible, however addition of FAD and tris (hydroxypropyl) phosphine can restore some enzyme activity. Group: Biochemicals. Alternative Names: (Z)-2-Chloro-5-(4,5-dihydro-5-oxo-4-((5-phenyl-2-furanyl)methylene)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzoic Acid, (Z)-2-Chloro-5-(5-oxo-4-((5-phenylfuran-2-yl)methylene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic Acid. Grades: Highly Purified. CAS No. 496807-64-8. Pack Sizes: 25mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 460.8. US Biological Life Sciences. | Worldwide |
Guanosine-5'-O-(1-Thiotriphosphate) Quick inquiry Where to buy Suppliers range | Guanosine-5'-O-(1-Thiotriphosphate) emerges as an indispensable compound within the biomedical industry serving as a substrate for diverse enzymatic reactions and a biophysical research instrument. Throughout investigations concerning GTP-binding proteins, signal transduction pathways and protein-protein interactions, its vital participation becomes apparent. Moreover, its utilization enables the exploration of key mechanisms involved in debilitating diseases, exemplified by cancer and neurological disorders. Synonyms: Alpha Thiol GTP; 1-Thio-GTP; Guanosine-5'-Rp-Alpha-Thio-Triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 81570-50-5. Molecular formula: C10H16N5O13P3S. Mole weight: 539.3. | |
N-Ethylmaleimide Quick inquiry Where to buy Suppliers range | N-Ethylmaleimide (NEM) is a derivative of maleic acid and is used as a reagent for alkylation and covalent modification of nucleophilic thiol residues on proteins. It acts as an irreversible inhibitor of all cysteine peptidases that alkylates the active site thiol group of the enzymes. Uses: Used in cancer research; a sulfhydryl reagent that is widely used in experimental biochemical studies. Synonyms: NEM; 1-Ethyl-1H-pyrrole-2,5-dione; ethylmaleimide. Grades: >98.0%(HPLC)(N). CAS No. 128-53-0. Molecular formula: C6H7NO2. Mole weight: 125.13. | |
OXi-4503 Quick inquiry Where to buy Suppliers range | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide/hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Synonyms: OXi4503; OXi 4503; CA1P; tetrasodium [3-methoxy-2-phosphonatooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate. Grades: >98%. CAS No. 288847-35-8. Molecular formula: C18H22O12P2. Mole weight: 492.31. | |
Oxidation-Reduction Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant natural products, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries. | |
Prasugrel Hydroxy Thiolactone Quick inquiry Where to buy Suppliers range | Prasugrel Hydroxy Thiolactone. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS002811. Format: Neat. | |
(R)-(+)-Thiolactomycin Quick inquiry Where to buy Suppliers range | (R)-(+)-Thiolactomycin. Uses: For analytical and research use. Group: Chiral Molecules; Enzyme Activators, Inhibitors & Substrates. CAS No. 82079-32-1. IUPAC Name: (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dienyl]thiophen-2-one. Molecular formula: C11H14O2S. Mole weight: 210.29. Catalog: APS82079321. SMILES: C\C(=C/[C@@]1(C)SC(=O)C(=C1O)C)\C=C. Format: Neat. | |
Thimerosal, 97.0-101.0% USP/BP/EP Quick inquiry Where to buy Suppliers range | Used in disinfecting irrigations, as a preservative in vaccines, drops and ointments for eyes, in blood plasmas as well as in verterinary medicine and for antiseptic surgical dressing. Thimerosal is used as an antibacterial and antifungal. It is used as a topical antiseptic on skin and mucous membranes. Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na++K+ dependent ATPases. Group: Biochemicals. Alternative Names: ((O-Carboxyphenyl)thio) ethylmercury sodium salt; Elcide 75; Elicide; Ethyl(2-mercaptobenzoato-S)mercury sodium salt; O-(Ethylmercurithio) benzoic acid sodium salt; Ethyl mercurithiosalicyl ic acid sodium salt; Ethyl (sodium O-mercaptobenzoato) mercury; Mercurothiolate; Ethyl(2-Mercaptobenzoate-S)-, sodium salt; Merfamin; Merthiolate; Merthiolate salt; Merthiolate sodium; Mertorgan; Merzonin; Merzonin sodium; Merzonin, sodium salt; SET; Sodium Ethylmercuric Thiosalicylate; Sodium O- (ethylmercurithio) benzoate; Sodium Ethyl mercurithiosalicyl ate; Sodium Merthiolate; Thimerosalate; Thimerosol; Thimersalate; Thiomerosal; Thiomersal; Thiomersalate. Grades: USP. CAS No. 54-64-8. Pack Sizes: 5g, 25g, 100g. Molecular Formula: C9H9HgO2SNa, Molecular Weight: 404.81. US Biological Life Sciences. | Worldwide |