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| Product | Description | |
|---|---|---|
| EO 1428 | EO 1428. Group: Biochemicals. Grades: Purified. CAS No. 321351-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| EO 1428 | EO 1428 is a selective inhibitor of p38α and p38β2 MAP kinase, but displays no activity at p38γ, p38δ, ERK1/2 and JNK1. EO 1428 inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 - 4, 5, 17, 30 and 74 nM, respectively) and acts against inflammation in murine models of acute and chronic dermatitis. Synonyms: EO-1428; EO 1428; EO1428; (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone. Grades: ≥98% by HPLC. CAS No. 321351-00-2. Molecular formula: C20H16BrClN2O. Mole weight: 415.71. |  |
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