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Epelsiban Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation. Uses: Premature ejaculation. Synonyms: GSK-557296; GSK 557296; GSK557296; GSK-557,296-B; (3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione. Grade: 98%. CAS No. 872599-83-2. Molecular formula: C30H38N4O4. Mole weight: 518.65. BOC Sciences 7
Epelsiban besylate This active molecular, also known as GSK-557296B, is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity over the related vasopressin receptors. Uses: Adenomyosis;infertility; premature ejaculation. Synonyms: GSK557296B; GSK-557296B; (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2-(morpholin-4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione monobenzenesulfonate. Grade: 98%. CAS No. 1159097-48-9. Molecular formula: C36H44N4O7S. Mole weight: 676.83. BOC Sciences 7

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