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| Product | Description | |
|---|---|---|
| Eplivanserin hemifumarate | Eplivanserin hemifumarate. Group: Biochemicals. Grades: Purified. CAS No. 130580-02-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Eplivanserin hemifumarate | Eplivanserin hemifumarate is a potent and selective 5-HT2A antagonist (IC50 = 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively) with no activity for dopamine, histamine and adrenergic receptors. It attenuates cocaine-induced hyperactivity, increases dopamine (DA) release in rat medial prefrontal cortex (mPFC) and potentiates haloperidol-induced DA release in the mPFC and nucleus accumbens. Synonyms: SR-46349B; SR 46349B; SR46349B; (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate. Grades: ≥98% by HPLC. CAS No. 130580-02-8. Molecular formula: C19H21FN2O2.1/2C4H4O4. Mole weight: 386.42. |  |
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