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| Product | Description | |
|---|---|---|
| EPZ020411 | EPZ020411, with potent anticancer activity, is an orally bioactive, selective inhibitor of PRMT6/8/1 with over 100-fold selective for other histone methyltransferases including four arginine methyltransferases (PRMT3, PRMT4, PRMT5, and PRMT7). Synonyms: N,N'-dimethyl-N'-[[5-[4-[3-[2-(oxan-4-yl)ethoxy]cyclobutyl]oxyphenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineEPZ020411; EPZ 020411; EPZ-020411CHEMBL3589039GTPL9243SCHEMBL17 62195749LN, N'-Di methyl -N- ( {3- [4- ( {trans-3- [2- (Tetra hydro-2h-Pyran-4-yl ) ethoxy] cyclobutyl } oxy) pheny l. CAS No. 1700663-41-7. Molecular formula: C25H38N4O3. Mole weight: 442.59. |  |
| EPZ020411 HCl | EPZ020411 hydrochloride is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM, and it displays >10-fold and 20-fold selectivity over PRMT1/8. Synonyms: EPZ-020411 hydrochloride. Grades: ≥97%. CAS No. 2070015-25-5. Molecular formula: C25H39ClN4O3. Mole weight: 479.06. | |
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