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| Product | Description | |
|---|---|---|
| ER-27319 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| ER-27319 | ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201010-95-9. Pack Sizes: 5 mg. Product ID: HY-138961. |  |
| ER-27319 maleate | ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204480-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108489. | |
| ER 27319 maleate | ER 27319 maleate is a selective Syk kinase inhibitor. It suppresses tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat and human mast cells, causing the abrogation of degranulation, TNF-α production (IC50 = 10 μM) and other related signaling events. Synonyms: ER27319 maleate; ER-27319 maleate; 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate; 9(10H)-Acridinone, 10-(3-aminopropyl)-3,4-dimethyl-, (2Z)-2-butenedioate (1:1); 3,4-Dimethyl-10-(3-aminopropyl)-9-acridone maleate. Grades: ≥99% by HPLC. CAS No. 1204480-26-1. Molecular formula: C18H20N2O.C4H4O4. Mole weight: 396.17. |  |
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