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| Product | Description | |
|---|---|---|
| Erythropoietin | Erythropoietin. Group: Biochemicals. Grades: Highly Purified. CAS No. 11096-26-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
| Erythropoietin | Produced by the kidneys,this glycoprotein is involved in red blood cell production. It has a predicted molecular mass of ~21 kDa but migrates at ~37 kDa on SDS-PAGE. Synonyms: Betapoietin; Ep; EPO; Epocim; Epocrin; Epoetin; Epogis S; Epolyrec; Eposim; Erythropoietins; Erytrostim; Heberitro; Hematopoietin; Hemax; Hemopoietin; Hempoietine; Neuro-EPO; PDpoetin; Repotin; YiBei. CAS No. 11096-26-7. Molecular formula: C134H226N38O41. Mole weight: 3025.49000. |  |
| Erythropoietin from mouse | recombinant, expressed in NSO cells, ?90% (SDS-PAGE), lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. |  |
| Erythropoietin Soluble Receptor human | >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Erythropoietin antibody produced in rabbit | IgG fraction of antiserum, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Erythropoietin Receptor antibody produced in goat | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Erythropoietin antibody produced in rat | clone 148438, purified immunoglobulin, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| 2-(1a-methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carboxamido)acetic acid | 2-(1a-methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carboxamido)acetic acid is an impurity of Roxadustat. Roxadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI). It promotes coordinated erythropoiesis through increasing endogenous erythropoietin, improving iron availability, and reducing hepcidin. Synonyms: (1a-methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carbonyl)glycine; Rosastat impurity 02. CAS No. 2301113-15-3. Molecular formula: C19H16N2O5. Mole weight: 352.35. | |
| C12-200 | C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1220890-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145405. |  |
| Cibinetide | Cibinetide (ARA290) is an EPO-derivative, acting as a specific agonist of erythropoietin/CD131 heteroreceptor, and used for neurological disease treatment. Uses: Scientific research. Group: Peptides. Alternative Names: ARA290. CAS No. 1208243-50-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0168. | |
| Cibinetide | Cibinetide is a non-erythropoietic erythropoietin (EPO) derivative. It acts as a specific agonist of erythropoietin/CD131 heteroreceptor, and is under clinical trials for the treatment of diabetic macular edema. Synonyms: ARA-290; ARA 290; ARA290; PHBSP; PH-BSP; PH BSP; H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH. Grades: >98%. CAS No. 1208243-50-8. Molecular formula: C51H84N16O21. Mole weight: 1257.3. | |
| Epo | Epo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ERYTHROPOIETIN RAT;EPO;erythropoietin from human urine*approx 100 units;Erythropoietin,from human urine;ERYTHROPOIETIN HUMAN, RECOMB. FROM CHO- CELLS, PGE W. 10 U;ERYTHROPOIETIN FROM HUMAN URINE*APPROX 5 00 UNITS PE;ERYTHROPOIETIN FROM HUMAN URINE*APPROX 100 UNITS PER;Erythropietin human. Product Category: Heterocyclic Organic Compound. Appearance: lyophilized powder. CAS No. 11096-26-7. Molecular formula: NULL. Mole weight: 0. Product ID: ACM11096267. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Epobis | Epobis is a nonerythropoietic and neuroprotective agonist of the erythropoietin receptor with anti-Inflammatory and memory enhancing effects. Grades: 98%. | |
| Epoetin beta | Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: rhEPO; EPOCH; Genetical recombination. CAS No. 122312-54-3. Pack Sizes: 500 U; 1000 U; 2000 U; 5000 U. Product ID: HY-114134. | |
| Ethyl 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-1-thio- β-D-glucopyranoside | Ethyl 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-1-thio- β-D-glucopyranoside is used to prepare β-human FSH-based glycopeptides containing an N-linked dodecasaccharide or chitobiose units. It is also used to synthesize a protected fucosylated biantennary N-glycan of erythropoietin. Group: Biochemicals. Grades: Highly Purified. CAS No. 115533-35-2. Pack Sizes: 25mg, 250mg. Molecular Formula: C30H31NO6S, Molecular Weight: 533.64. US Biological Life Sciences. | Worldwide |
| FG-2216 | FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2) , with an IC 50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641. | |
| HIF-PHD Inhibitor II, JNJ-42041935 (HIF Prolyl Hydroxylase Inhibitor II, 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid) | A cell-permeable benzimidazolopyrazole compound that acts as an active-site binding, iron insensitive, 2-oxoglutarate competitive, reversible and potent inhibitor of PHD1, 2 and 3 isozymes (pKi=7.91, 7.29 and 7.65, respectively). Displays >100-fold selectivity over FIH (factor inhibiting hydroxylase; pIC50 ~4) and minimal affinity towards a panel of receptors, enzymes and kinases. Shown to elevate HIF-1a levels in Hep3B cells and stimulate erythropoietin secretion in mice, and reverse inflammation-induced anemia in rats (100uM/kg). Shown to inhibit malate dehydrogenase 2 (MDH2) activity and suppress mitochondrial respiration. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?ClF?N?O?, Molecular Weight: 346.7. US Biological Life Sciences. | Worldwide |
| LDN-211904 (N-(2-chlorophenyl)-6-(piperidin-4-yl)imidazo[1,2-a]pyridine-3-carboxamide Ooxalate, EphB3 Inhibitor) | A pyrazolo[1,5-a]pyridine derivative that acts as an potent and reversible EphB3 receptor tyrosine kinase inhibitor with an IC50 of 79nM with good mouse liver microsomal stability and aqueous solubility. Shown to suppress EphB3-induced autophosphorylation of EphB3 receptor at 10uM in cells. When profiled against a panel of 288 kinases at 5uM, found to also inhibit most of the Eph (Erythropoietin-producing hepatocellular carcinoma) receptor kinases including EphA1, EphA2, EphA3, EphA4, EphA5, EphA8, EphB1, EphB2, EphB3, EphB4 and other tyrosine kinases, but not EphA6 and EphA7, and is non-inhibitory towards non-RTK kinases screened except for p38α, p38b, and Qik. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 444.9. US Biological Life Sciences. | Worldwide |
| LDN-211904 oxalate | LDN-211904 is an inhibitor of erythropoietin-producing hepatocellular carcinoma (Eph) receptors. It was profiled for inhibitory activity against a panel of 288 kinases and found to be quite selective for tyrosine kinases. Synonyms: LDN-211904; LDN 211904 oxalate; LDN211904 oxalate; N-(2-chlorophenyl)-6-piperidin-4-ylimidazo[1,2-a]pyridine-3-carboxamide oxalate. Grades: ≥98%. CAS No. 1198408-78-4. Molecular formula: C19H19ClN4O·C2H2O4. Mole weight: 444.9. | |
| Molidustat | Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase ( HIF-PH ) with IC 50 values of 480 nM, 280 nM, and 450 nM for PHD1 , PHD2 , and PHD3 , respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 85-3934. CAS No. 1154028-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12654. | |
| Oclacitinib | Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nm. Oclacitinib had minimal effects on cytokines that did not activate the JAK1 enzyme in cells (erythropoietin, granulocyte/macrophage colony-stimulating factor, IL-12, IL-23; IC50 's > 1000 nm). These results demonstrate that oclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs. Synonyms: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-; trans-N-Methyl-4- (methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-ylamino) cyclohexanemethanesulfonamide; JAKi; PF 03394197. Grades: 98%. CAS No. 1208319-26-9. Molecular formula: C15H23N5O2S. Mole weight: 337.44. | |
| Peginesatide | Peginesatide is an erythropoietic agent, a functional analog of erythropoietin. Synonyms: AF37702; AF 37702; Hematide; HSDB 8181. CAS No. 910576-32-8. Molecular formula: C233H352N62O60S6. Mole weight: 5174.06. | |
| Roxadustat | Roxadustat is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FG-4592. CAS No. 808118-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13426. | |
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