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| Product | Description | |
|---|---|---|
| ESI-09 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ESI-09 | ESI-09 is a novel noncyclic nucleotide EPAC antagonist with IC 50 values of 3.2 and 1.4 μM for EPAC1 and EPAC2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 263707-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16704. |  |
| ESI-09 | ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation, as well as EPAC-mediated insulin secretion in pancreatic β cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer. Synonyms: ESI09; ESI 09; ESI-09. Grades: >98%. CAS No. 263707-16-0. Molecular formula: C16H15ClN4O2. Mole weight: 330.77. |  |
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