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Estradiol Hemihydrate is the hemihydrate form of estradiol, the most potent, naturally produced estrogen. Estradiol hemihydrate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. Alternative Names: beta-Estradiol semihydrate. UNII-CXY7B3Q98Z. CXY7B3Q98Z. CAS No. 35380-71-3. Product ID: API35380713. Molecular formula: C36H50O5. Mole weight: 562.8. EINECS: 631-198-2. SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.O. Category: APIs for Estrogens.
Estradiol Hemihydrate
Estradiol Hemihydrate. Uses: For analytical and research use. Group: Api standards; british pharmacopoeia; european pharmacopoeia (ph. eur.); impurity standards; pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: beta-Estradiol semihydrate,Estradiol Benzoate Imp. A (EP), Estradiol Valerate Imp. A (EP), Estriol Imp. D (EP), beta-Estradiol hemihydrate, Ethinylestradiol Imp. D (EP) as Hemihydrate, Estradiol Valerate Imp. A (EP) as Hemihydrate, Estradiol Hemihydrate, Estra-1,3,5(10)-triene-3,17-diol (17beta)-, hydrate (2:1) (9CI), Estradiol Benzoate Imp. A (EP) as Hemihydrate, Ethinylestradiol Imp. D (EP), Estriol Imp. D (EP) as Hemihydate. CAS No. 35380-71-3. IUPAC Name: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol;hydrate. Molecular formula: 2C18H24O2.H2O. Mole weight: 562.78. Catalog: APS35380713. SMILES: O.C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O.C[C@]56CC[C@H]7[C@@H](CCc8cc(O)ccc78)[C@@H]5CC[C@@H]6O. Format: Neat.
Estradiol Hemihydrate Impurity D
An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: delta9,11-Estradiol. Grade: > 95%. CAS No. 791-69-5. Molecular formula: C18H22O2. Mole weight: 270.37.
4-Methyl Estradiol
4-Methyl Estradiol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-Methylestra-1,3,5(10)-triene-3,17beta-diol, 4-Methylestradiol, Estradiol Hemihydrate Imp. C (EP). CAS No. 6171-48-8. IUPAC Name: (8R,9S,13S,14S,17S)-4,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C19H26O2. Mole weight: 286.41. Catalog: APS6171488. SMILES: Cc1c(O)ccc2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@@H]3CCc12. Format: Neat.
?9(11)-Estradiol
?9(11)-Estradiol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Estradiol Hemihydrate Imp. D (EP),Estra-1,3,5(10),9(11)-tetraene-3,17beta-diol, 9,11-Didehydroestradiol. CAS No. 791-69-5. IUPAC Name: (8S,13S,14S,17S)-13-methyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C18H22O2. Mole weight: 270.37. Catalog: APS791695. SMILES: C[C@]12CC=C3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O. Format: Neat.
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