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Etalocib Etalocib (LY293111), an orally active leukotriene B 4 receptor antagonist, inhibits the binding of [ 3 H]LTB 4 , with a K i of 25 nM. Etalocib (LY293111) prevents LTB 4 -induced calcium mobilization with an lC 50 of 20 nM. Etalocib (LY293111) induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY293111; VML 295. CAS No. 161172-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13628. MedChemExpress MCE
Etalocib LY293111, a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. LY293111 has antineoplastic activity in a variety of preclinical models. Synonyms: LY293111; VML 295; 2-[3-[3-[(5-Ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic Acid; 2- [2-Propyl-3- [3- [2-ethyl-4- (4-fluorophenyl) -5-hydroxyphenoxy] propoxy] phenoxy] benzoic acid. Grades: ≥98%. CAS No. 161172-51-6. Molecular formula: C33H33FO6. Mole weight: 544.61. BOC Sciences 11

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