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| Product | Description | |
|---|---|---|
| Etelcalcetide hydrochloride | Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride. CAS No. 1334237-71-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1955A. |  |
| Etelcalcetide hydrochloride | Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Synonyms: AMG-416; AMG 416; AMG416; Etelcalcetide hydrochloride; KAI-4169; KAI-4169-HCl; ONO-5163; Parsabiv; Telcalcetide; Velcalcetide; Velcalcetide hydrochloride;N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride;1262780-97-1 (free). Grades: >98%. CAS No. 1334237-71-6. Molecular formula: C38H74ClN21O10S2. Mole weight: 1084.72. |  |
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