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| Product | Description | |
|---|---|---|
| Ethyl arachidonate | Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. Uses: Arachidonic acid (aa) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. phospholipase a2 releases aa from the membrane phospholipids in response to inflammation. Synonyms: Arachidonic acid ethyl ester. Grades: 95%. CAS No. 1808-26-0. Molecular formula: C22H36O2. Mole weight: 332.52. |  |
| Ethyl arachidonate | Ethyl arachidonate is a lipophilic esterified form of arachidonic acid (AA) and can be added into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. Ethyl arachidonate is the main species of fatty acid ethyl esters (FAEE) in brain of alcohol-intoxicated subjects [1]. Uses: Scientific research. Group: Natural products. CAS No. 1808-26-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013214. |  |
| Ethyl arachidonate,10% | Ethyl arachidonate,10%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ethyl arachidonate, Arachidonic acid ethyl ester, Arachidonic acid, ethyl ester, A9135_SIGMA, ZINC04534005, CID5367369, 5,8,11,14-Eicosatetraenoic acid, ethyl ester, Ethyl 5,8,11,14-eicosatetraenoate (all Z), LS-63785, Arachidonic acid, ethyl ester (6CI,7CI,8CI), 5,8,11,14-Eicosatetraenoic acid ethyl ester, 5,8,11,14-Eicosatetraenoic acid, ethyl ester, (all Z)-, 5,8,11,14-Eicosatetraenoic acid, ethyl ester, (all-Z)-, 1808-26-0. Product Category: Heterocyclic Organic Compound. CAS No. 1808-26-0. Molecular formula: C22H36O2. Mole weight: 332.53. Purity: 0.96. IUPACName: ethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate. Canonical SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)OCC. Density: 0.899g/cm³. Product ID: ACM1808260. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CK-2130 | CK-2130 is a bio-active imidazolone developed to treat congestive heart failure. It inhibited human platelet aggregation produced by adenosine diphosphate and sodium arachidonate. Uses: Ck-2130 is used to treat congestive heart failure. Synonyms: CK 2130; CK-2130; CK2130. 4-Ethyl-1,3-dihydro-5-[4-[(2-methyl-1H-imidazol)-1-yl]benzoyl]-2H-imidazol-2-one;CK2130;4-Ethyl-5-[4-(2-methylimidazol-1-yl)benzoyl]-1,3-dihydroimidazol-2-one. Grades: >98 %. CAS No. 101184-07-0. Molecular formula: C16H16N4O2. Mole weight: 296.33. | |
| fatty-acyl-ethyl-ester synthase | The reaction, forms ethyl esters from fatty acids and ethanol in the absence of coenzyme A or ATP. Best substrates are unsaturated octadecanoic acids; palmitate, stearate and arachidonate also act, but more slowly. Group: Enzymes. Synonyms: FAEES. Enzyme Commission Number: EC 3.1.1.67. CAS No. 90119-16-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3495; fatty-acyl-ethyl-ester synthase; EC 3.1.1.67; 90119-16-7; FAEES. Cat No: EXWM-3495. |  |
| 2-Arachidonyl glycerol-d5 | 2-Arachidonyl glycerol-d5. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-(hydroxymethyl) ethyl-d5 Ester; (all-Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1- (hydroxymethyl)ethyl-d5 Ester; 2-Monoarachidonoylglycerol-d5. Product Category: Heterocyclic Organic Compound. CAS No. 1215168-37-8. Molecular formula: C23H33D5O4. Mole weight: 383.58. Purity: 0.96. IUPACName: (1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl) (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate. Canonical SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO. Product ID: ACM1215168378. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Palmitoylglycerol | 2-Palmitoylglycerol is an endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol. It is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoylglycerol does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase. Synonyms: 2-Hydroxy-1-(hydroxymethyl)ethyl hexadecanoic acid ester; 2-Monohexadecanoylglycerol; 2-Monopalmitin; 2-Monopalmitoyl-sn-glycerol; 2-Monopalmitoylglycerol; 2-Palmitoylglycerol; Glycerol-β-palmitate; Palmitic Acid β-monoglyceride; β-Monopalmitin. CAS No. 23470-00-0. Molecular formula: C19H38O4. Mole weight: 330.51. | |
| (5Z,8Z,11Z,14Z)-2-[[Tris(1-methylethyl)silyl]oxy]-5,8,11,14-eicosatetraenoic Acid 1-[[[Tris (1-methylethyl) silyl]oxy]methyl]ethyl Ester | (5Z,8Z,11Z,14Z)-2-[[Tris(1-methylethyl)silyl]oxy]-5,8,11,14-eicosatetraenoic Acid 1-[[[Tris (1-methylethyl) silyl]oxy]methyl]ethyl Ester is an intermediate in the synthesis of 2-Arachidonoylglycerol (A765050), an major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 223259-26-5. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Arachidonoyl serinol | Arachidonoyl Serinol is an amide bond-containing analogue of 2-arachidonoylglycerol, which exhibited weak CB1 receptor agonistic activity. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain. It is a product of increased inositol phospholipid metabolism. Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom gives arachidonoyl serinol. Arachidonoyl serinol is much more stable than 2-AG. Synonyms: N-arachidonoyl dihydroxypropylamine; 183718-70-9; AA dihydroxypropylamine; (5Z,8Z,11Z,14Z)-N-(1,3-dihydroxypropan-2-yl)icosa-5,8,11,14-tetraenamide; CHEMBL141463; Arachidonoyl Serinol; N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(1,3-dihydroxy-propyl-2-amine); 5,8,11,14-Eicosatetraenamide,N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, (5Z,8Z,11Z,14Z)-; N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; Arachidonoylserinol; CHEBI:183197; QHELXIATGZYOIB-DOFZRALJSA-N; HMS3649C07; BDBM50054465; LMFA08020072; SR-01000946557; SR-01000946557-1; (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2-hydroxy-1-hydroxymethyl-ethyl)-amide. Grades: ≥98%. CAS No. 183718-70-9. Molecular formula: C23H39NO3. Mole weight: 377.6. | |
| Arachidonyl serotonin | Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor, which is responsible for inactivation of anandamide and other endogenous cannabinoids. Its IC50 values are 37-40 nM and 5.6 μM for TRPV1 and FAAH respectively. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 μM. It is a very tight binding, competitive inhibitor of FAAH. It does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. It displays strong analgesic activity against both acute and chronic peripheral pain in rodents. Synonyms: AA-5HT; AA5HT; AA 5HT; N-arachidonoyl-serotonin; Arachidonoyl serotonin; N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; AA-5HT; AA5HT; N-arachidonoyl-serotonin; N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide. CAS No. 187947-37-1. Molecular formula: C30H42N2O2. Mole weight: 462.67. | |
| AX 048 | Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate (AX 048) is a PLA2 (Phospholipase A2) and PGE2 (Prostaglandin E2) inhibitor. PLA2 is known as calcium-dependent cytosolic PLA2 (cPLA2), which selectively releases arachidonic acid from membrane phospholipids. It plays a central role in initiating the synthesis of prostaglandins and leukotrienes. This compound also contains a specific affinity for group IVA cPLA2 which moderates antihyperalgesia effects. Synonyms: AX-048; AX 048; Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester; UNII-8782Z45DLV; 8782Z45DLV; Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester; ethyl 4-(2-oxohexadecanoylamino)butanoate; ethyl 4-(2-oxohexadecanamido)butanoate; CHEMBL574723; SCHEMBL4781039; DTXSID60236282; AKOS040755666; ethyl 4-[(2-oxohexadecanoyl)amino] butanoate; Q27269809; 4- [(1, 2- dioxohexadecyl)amino]- butanoic acid, ethyl ester. Grades: ≥98%. CAS No. 873079-69-7. Molecular formula: C22H41NO4. Mole weight: 383.6. | |
| CV-6209 chloride | CV-6209 is a potent platelet-activating factor (PAF) receptor antagonist, which inhibits aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little effect on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo. Synonyms: 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-pyridinium monochloride. Grades: ≥95%. CAS No. 100488-87-7. Molecular formula: C34H60N3O6·Cl. Mole weight: 642.3. | |
| KML-29 | KML-29 is an extremely specific monoacylglycerol lipase (MAGL) inhibitor. KML-2 should be useful to distinguish between actions of 2-arachidonoyl glycerol (an endogenous ligand of cannabinoid receptors that is deactivated by MAGL) and anandamide, another endocannabinoid. Group: Biochemicals. Alternative Names: 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic Acid 2,2,2-Trifluoro-1-(trifluoromethyl)ethyl Ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4- (Bis (benzo[d][1, 3]dioxol-5-yl) (hydroxy) methyl) piperidine-1-carboxylate; KML29. Grades: Highly Purified. CAS No. 1380424-42-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Nafazatrom | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
| N-Arachidonoyl dopamine | N-Arachidonoyl dopamine (NADA) is an endocannabinoid isolated from bovine brain. It acts as an agonist of CB1 and inhibitor of vanilloid TRPV1 receptors. NADA promotes calcium mobilization via Gq-dependent processes and some CB1 receptor trafficking. Synonyms: NADA; (5Z,8Z,11Z,14Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]icosa-5,8,11,14-tetraenamide. Grades: ≥98%. CAS No. 199875-69-9. Molecular formula: C28H41NO3. Mole weight: 439.6. | |
| Oleoyl serotonin | Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, which is a dual antagonist of FAAH/TRPV1 channel. Oleoyl serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM). Synonyms: (9Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]octadec-9-enamide; N-(2-(5-Hydroxy-1H-indol-3-yl)ethyl)-9Z-octadecenamide. Grades: ≥98%. CAS No. 1002100-44-8. Molecular formula: C28H44N2O2. Mole weight: 440.7. | |
| Palmitoyl serotonin | Palmitoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, an antagonist of FAAH. Study has shown that palmitoyl serotonin attenuates the development of L-DOPA-induced dyskinesia (LID) and enhance of ERK1/2 phosphorylation and FosB/ΔFosB expression in the hemi-parkinsonian mouse model. Synonyms: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]hexadecanamide; Palmitoylserotonin. Grades: ≥98%. CAS No. 212707-51-2. Molecular formula: C26H42N2O2. Mole weight: 414.6. | |
| Zileuton-d4 (major) | An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4;A-64077-d4; Abbott 64077-d4; Leutrol-d4; Zyflo-d4. Grades: Highly Purified. CAS No. 1189878-76-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Zileuton (N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea,. A-64077, Abbott 64077, Leutrol, Zyflo) | An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea;A-64077; Abbott 64077; Leutrol; Zyflo. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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