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| Product | Description | |
|---|---|---|
| EX 527 | EX 527. Group: Biochemicals. Grades: Purified. CAS No. 49843-98-3. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| EX 527 (Selisistat, EX527, SIRT1 Inhibitor III) | EX 527 (Selisistat, EX527, SIRT1 Inhibitor III). Group: Biochemicals. Alternative Names: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide. Grades: Highly Purified. CAS No. 49843-98-3. Pack Sizes: 10mg. Molecular Formula: C13 H13 ClN 2, Molecular Weight: 248.7. US Biological Life Sciences. | Worldwide |
| EX-527 | EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. Synonyms: SEN0014196; EX-527; EX-527; EX-527; Selisistat. Grades: >98%. CAS No. 49843-98-3. Molecular formula: C13H13ClN2O. Mole weight: 248.71. |  |
| EX-527 R-enantiomer | EX-527 R-enantiomer is the R-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. It is a negative control of the active form EX-527 S-enantiomer. Synonyms: Selisistat R-enantiomer; (R)-Selisistat; EX-527(R); EX 527(R); EX527(R). Grades: >98%. CAS No. 848193-69-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 S-enantiomer | EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. Synonyms: Selisistat S-enantiomer; EX-527(S); (S)-Selisistat; EX 527(S); EX527(S); EX-527S; EX527S. Grades: >98%. CAS No. 848193-68-0. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| 2-Acetamido-5-nitrothiazole | Nithiamide is efficient in preventing and treating swine dysentery in experimentally inoculated pigs. Synonyms: CL 5279; CL5279; CL-5279; Nithiamide; NSC 45914; NSC-45914; NSC45914. Grades: >98%. CAS No. 140-40-9. Molecular formula: C5H5N3O3S. Mole weight: 187.18. | |
| 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate | 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate, a paramount constituent employed in biomedical research, serves as an invaluable tool in the exploration and advancement of remedies for select ailments. Its utility in the realm of biomedicine extends towards the scrutiny of its prowess as a curative agent for diverse maladies. Molecular formula: C10H17ClN5O12P3. Mole weight: 527.64. | |
| 2'-Deoxy-2'-fluorocytidine 5'-monophosphate triethylammonium | 2'-Deoxy-2'-fluorocytidine 5'-monophosphate triethylammonium is a potential biomedical compound product with antiviral efficacy, which has been shown to excel in combating harmful viral invasions, especially those associated with hepatitis C and COVID-19. It is effective in controlling and containing these diseases by inhibiting viral replication and reducing viral burden. Synonyms: [(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate di(triethylammonium); 2'-Deoxy-2'-Fluorocytidine 5'-(Dihydrogen Phosphate) triethylammonium. Grades: ≥95%. Molecular formula: C21H43FN5O7P. Mole weight: 527.57. | |
| 3-(3-amino-3-carboxypropyl)uridine | 3-(3-amino-3-carboxypropyl)uridine, an indispensable compound extensively applied in biomedical research and pharmaceutical advancement, assumes a pivotal function in the amalgamation of nucleic acids and RNA alteration. Its multifaceted attributes make it an invaluable tool for unraveling the intricate intricacies of RNA's structure, function, and the impact of selective modifications on a diverse array of ailments, encompassing cancer and neurodegenerative disorders. Synonyms: 1(2H)-Pyrimidinebutanoic acid, a-amino-3,6-dihydro-2,6-dioxo-3-b-D-ribofuranosyl-; 3-(3-Amino-3-carboxypropyl)-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione; 1(2H)-Pyrimidinebutanoic acid, alpha-amino-3,6-dihydro-2,6-dioxo-3-beta-D-ribofuranosyl-. Grades: 97%. CAS No. 52745-94-5. Molecular formula: C13H19N3O8. Mole weight: 345.19. | |
| 5-Carboxy-CTP | 5-Carboxy-CTP is a powerful tool in compound used for labeling and detection of RNA in numerous diagnostic applications. This modified nucleotide is employed to track RNA transcription and translation aiding in studying gene expression and protein enhancement. By incorporating into RNA molecules, 5-Carboxy-CTP facilitates the analysis of RNA function and regulation in various diseases and drug development. Synonyms: 5-Carboxycytidine-5'-Triphosphate; 5-caCTP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N3O16P3. Mole weight: 527.1. | |
| 7-Propargylamino-7-deaza-ddATP | 7-Propargylamino-7-deaza-ddATP, a nucleoside triphosphate derivative, is presently being researched to identify its therapeutic potential in dealing with viral diseases such as HIV and Hepatitis B. Additionally, this modified version of nucleotide triphosphate, apart from its antiviral properties, offers exciting possibilities to advance our knowledge on genomic replication and restoration. Synonyms: 7-Deaza-7-propargylamino-2',3'-dideoxyadenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C14H20N5O11P3 (free acid). Mole weight: 527.26 (free acid). | |
| Atopaxar | Atopaxar is a Protease-activated receptor-1 (PAR-1) inhibitor. It can inhibit the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 value of 0.019μM. Atopaxar exhibits potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 values of 0.064 and 0.031μM. It may become a therapeutic option for atherothrombotic disease. In May 2012, Phase-II for Acute coronary syndromes in European Union was discontinued. Uses: Acute coronary syndromes. Synonyms: E5555; E-5555; E 5555; ER-172594-00; ER172594-00; ER 172594-00; Atopaxar;1-(3-(tert-butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethan-1-one;474550-69-1(hydrobromide). Grades: 98%. CAS No. 751475-53-3. Molecular formula: C29H38FN3O5. Mole weight: 527.64. | |
| Bathophenanthrolinedisulfonic acid disodium | Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris (bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 52746-49-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W127790. |  |
| BAY-588 | BAY-588 is a glucose transporter inhibitor and derivative of BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. It selectively inhibits glucose transporter 4 (Glut4), Glut1, and Glut3 over Glut2 with IC50 values of 0.5, 1.18, 5.47, and >10 μM, respectively, in CHO cells expressing human recombinant transporters. Synonyms: BAY 588; BAY588; N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide. Grades: ≥98%. CAS No. 1799759-24-2. Molecular formula: C27H25F4N5O2. Mole weight: 527.5. | |
| Beta-asarone | Beta-asarone is an orally active and BBB-penatrable anti-inflammatory agent and neuroprotective agent, which is the major ingredient of Acorus tatarinowii Schott. Beta-asarone can protect nerve cells from apoptosis and autophagy , inhibit expression of α-synuclein , as well as myocardial protection. Beta-asarone can be used in the study of neurological and cardiovascular diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 5273-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1501. | |
| Beta-asarone (Standard) | Beta-asarone (Standard) is the analytical standard of Beta-asarone. This product is intended for research and analytical applications. Beta-asarone is an orally active and BBB-penatrable anti-inflammatory agent and neuroprotective agent, which is the major ingredient of Acorus tatarinowii Schott. Beta-asarone can protect nerve cells from apoptosis and autophagy , inhibit expression of α-synuclein , as well as myocardial protection. Beta-asarone can be used in the study of neurological and cardiovascular diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 5273-86-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1501R. | |
| β-Glucosidase from Clostridium thermocellum, Recombinant | Beta-glucosidase is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose). It is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose. Group: Enzymes. Synonyms: EC 3.2.1.21; gentiobiase; cellobiase; emulsin; elaterase; aryl-beta-glucosidase; beta-D-glucosidase; beta-glucoside glucohydrolase; arbutinas. Enzyme Commission Number: EC 3.2.1.21. CAS No. 9001-42-7. Purity: > 95 % as judged by SDS-PAGE. β-Glucosidase. Mole weight: 52700 Da. Activity: 33 U/mg. Storage: Store at -20°C (shipped at room temperature). Form: Supplied in 35 mM HEPES buffer, pH 7.8, containing 750 mM NaCl, 5 mM imidazole, 3.5 mM CaCl2, 0.02 % (w/v) sodium azide and 25 % (v/v) glycerol. Source: Clostridium thermocellum DSM 1237. EC 3.2.1.21; gentiobiase; cellobiase; emulsin; elaterase; aryl-beta-glucosidase; beta-D-glucosidase; beta-glucoside glucohydrolase; arbutinase; amygdalinase; p-nitrophenyl beta-glucosidase; primeverosidase; amygdalase; linamarase; salicilinase; beta-1,6-glucosidase. Cat No: NATE-1182. |  |
| blood-group-substance endo-1,4-β-galactosidase | Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to a 1,3-α-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-α-D-fucosyl residue. Group: Enzymes. Synonyms: endo-β-galactosidase (ambiguous); blood-group-substance 1,4-β-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.102. CAS No. 52720-51-1. Endo-β-galactosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3785; blood-group-substance endo-1,4-β-galactosidase; EC 3.2.1.102; 52720-51-1; endo-β-galactosidase (ambiguous); blood-group-substance 1,4-β-D-galactanohydrolase. Cat No: EXWM-3785. | |
| D-Gluconic acid copper (II) salt | D-Gluconic acid copper (II) salt, a biomedical marvel, possesses exceptional efficacy in combating copper deficiency accompanied by associated ailments. This remarkable product stands as a paramount provider of copper ions, instrumental in orchestrating a myriad of intricate physiological mechanisms. Deployed extensively within the realms of the pharmaceutical and biomedical sectors, this sublime entity exhibits immense promise in ameliorating diverse copper-related disorders, thus paving the way for improved therapeutic interventions. Synonyms: Copper gluconate. CAS No. 527-09-3. Molecular formula: C6H11O7 Cu. Mole weight: 226.93. | |
| Erythromycin B | Erythromycin B is a minor co-metabolite of erythromycin produced by fermentation of Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. An impurity of Erythromycin. Uses: Anti-bacterial agents. Synonyms: Erythromycin B; Oxacyclotetradecane, erythromycin deriv.; 12-Deoxyerythromycin; Abbott 24091; Berythromycin. Grades: >95%. CAS No. 527-75-3. Molecular formula: C37H67NO12. Mole weight: 717.93. | |
| Esorubicin | Esorubicin is a synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause more severe myelosupression compared to other compounds within the anthracycline class. Uses: Antibiotics, antineoplastic. Synonyms: Deoxyadriamycin; Deoxydoxorubicin; IMI-58; IMI 58; IMI58; (8S,10S)-10-[[(2S,4R,6S)-4-Aminotetrahydro-6-methyl-2H-pyran-2-yl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; [2S-[2α(8R*, 10R*), 4β, 6β]]-10-[(4-Aminotetrahydro-6-methyl-2H-pyran-2-yl)oxy]-7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5, 12-naphthacenedione; 4'-Deoxyadriamycin; 4'-Deoxydoxorubicin; NSC 267469. CAS No. 63521-85-7. Molecular formula: C27H29NO10. Mole weight: 527.53. | |
| Fmoc-4-bis(2-chloroethyl)amino-L-phenylalanine | Fmoc-Phe(Cl2)2-OH is a derivative of phenylalanine, which is an essential amino acid that must be consumed from external sources. Fmoc-Phe(Cl2)2-OH is a common building block in solid-phase peptide synthesis (SPPS) because it can be selectively deprotected and coupled to other amino acids. This compound was originally synthesized in 1997 by Barral et al. and has since become a widely used tool in peptide chemistry. Uses: Fmoc-phe(cl2)2-oh is commonly used in spps to synthesize peptides with biological activity. this compound is also used in medicinal chemistry to develop new drugs and small molecules. fmoc-phe(cl2)2-oh has been used in a variety of scientific experiments, including studies of protein-protein interactions, drug discovery, and structure-activity relationship studies. Product Category: Amino Acids. CAS No. 1217809-60-3. Molecular formula: C28H28Cl2N2O4. Mole weight: 527.4. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-3-[4-[bis(2-chloroethyl)amino]phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(C=C4)N(CCCl)CCCl)C(=O)O. Product ID: ACM1217809603. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Synonyms: CO-101; CO101; CO 101; CP-4126; CP4126; CP 4126. CAS No. 210829-30-4. Molecular formula: C27H43F2N3O5. Mole weight: 527.654. | |
| Ginsenoside Rd | Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC 50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca 2+ influx. Ginsenoside Rd inhibits CYP2D6 , CYP1A2 , CYP3A4 , and CYP2C9 , with IC 50 s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Gypenoside VIII. CAS No. 52705-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0043. | |
| GT 949 | GT 949 is a potent and selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM) which exhibits no significant effect on DAT, SERT and NET or NMDA receptors. Synonyms: 3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one. Grades: ≥98%. CAS No. 460330-27-2. Molecular formula: C30H37N7O2. Mole weight: 527.66. | |
| lactosylceramide 4-α-galactosyltransferase | For explanation of superscript II in systematic name, see 2-carb.37. Group: Enzymes. Synonyms: Galβ1-4Glcβ1-Cer α1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide 4II-α-D-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.228. CAS No. 52725-57-2. Galactosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2457; lactosylceramide 4-α-galactosyltransferase; EC 2.4.1.228; 52725-57-2; Galβ1-4Glcβ1-Cer α1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide 4II-α-D-galactosyltransferase. Cat No: EXWM-2457. | |
| Methyl 2,3,4,-Tri-O-benzyl-6-bromo-6-deoxy-D-galactopyranoside | Methyl 2,3,4,-Tri-O-benzyl-6-bromo-6-deoxy-D-galactopyranoside, an immensely precious compound within the biomedical sector, manifests intricate characteristics and an extraordinary chemical configuration. Its extensive employment lies in the amalgamation of unprecedented pharmaceuticals and remedies for diverse ailments. This compound exhibits exceptional potential as an inhibitor, specifically targeting select enzymes implicated in the advancement of certain maladies. Synonyms: 3,4,5-Tris-benzyloxy-2-bromomethyl-6-methoxy-tetrahydropyran. Molecular formula: C28H31BrO5. Mole weight: 527.45. | |
| MK0533 | MK0533 is a novel selective peroxisome proliferator-activated receptor gamma modulator. It is used for the treatment of type 2 diabetes mellitus. It reduces potential to increase plasma and extracellular fluid volume. It showed diminished maximal activity in cell-based transcription activation assays and attenuated gene signatures in adipose tissue. Uses: Mk0533 is used for the treatment of type 2 diabetes mellitus. Synonyms: MK-0533; MK 0533; (R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid. Grades: 98%. CAS No. 668455-28-5. Molecular formula: C28H24F3NO6. Mole weight: 527.50. | |
| N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite | N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite, a fundamental asset within the biomedicine domain, exhibits immense complexity and variation. This pivotal compound facilitates the synthesis of customized oligonucleotides, enabling precise gene or sequence targeting associated with phenomena, including cancer, viral infections, and genetic disorders. Its unrivaled efficacy seamlessly integrates into nucleic acid chains, empowering researchers to comprehensively explore and devise therapeutic interventions for diverse pathological afflictions. Molecular formula: C22H34N5O8P. Mole weight: 527.51. | |
| N4-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine | N4-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine, a remarkable biomedical entity, exhibits profound efficacy in addressing specific ailments and pathologies. In the realm of biomedicine, this compound has garnered immense attention owing to its auspicious implications in the synthesis of antiviral agents and nucleoside analogs targeting diverse viral afflictions. Synonyms: 3',5'-O-TIPPS-N4-acetylcytidine; N4-Acetyl-3',5'-O-TIPPS-cytidine; N4-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-cytidine. CAS No. 85335-73-5. Molecular formula: C23H41N3O7Si2. Mole weight: 527.76. | |
| NF110 | NF110 is a P2X 3 receptor antagonist ( K i=36 nM) and inactive toward P2Y receptors stably expressed (IC 50 s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC 50 = 527 nM) in rat dorsal root ganglia neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111150-22-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108671. | |
| PD-153035 | PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also upregulates the expression of the tumor suppressor retinoic acid receptor-beta 2 (RAR-beta2). Uses: Antineoplastic agents. Synonyms: AG 1517; AG1517; AG-1517; NSC 669364; NSC669364; NSC-669364; PD 153035; PD153035; SU 5271; SU5271; SU-5271; WHI-P 79. Grades: >98%. CAS No. 153436-54-5. Molecular formula: C16H14BrN3O2. Mole weight: 360.211. | |
| PyOxim | PyOxim is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Synonyms: pyoxime; AS-10531; SC-13336; CS-0068035; K-4853; J-009012; (Ethyl cyano(hydroxyimino)acetato)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate; [cyano- (ethoxycarbonyl) methyleneaminooxy]tris (1-pyrrolidinyl) phosphonium hexafluorophosphate; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)?-[ethyl 2-cyano-2-[(hydroxy-κO)?imino]?acetato]?tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(?1-). Grades: > 98% (HPLC). CAS No. 153433-21-7. Molecular formula: C17H29F6N5O3P2. Mole weight: 527.38. | |
| Ribocil | Ribocil, a newly developed riboswitches chemical modulator, could selectively restrain the expression of GFP and probably influence bacterial cell growth. IC50: 0.3 μM (EC50). Uses: Ribocil is a newly developed riboswitches chemical modulator and could selectively restrain the expression of gfp and probably influence bacterial cell growth. Synonyms: Ribocil; CS-5272; CS 5272; CS5272. Grades: 98%. CAS No. 1381289-58-2. Molecular formula: C19H22N6OS. Mole weight: 382.48. | |
| SBC-115076 | SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Synonyms: SBC-115076; SBC 115076; SBC115076. Grades: 98%. CAS No. 489415-96-5. Molecular formula: C31H33N3O5. Mole weight: 527.62. | |
| Scandium Sulfate | Scandium Sulfate. Grades: 99.99% Extremely High (>=99%). CAS No. 52788-54-2. Pack Sizes: Gram Quantities: 1 gm , 5 gm. Order Number: 3154. |  www.prochemonline.com |
| Sodium Gluconate | Sodium D-Gluconate has use as an additive in processed foods, with the potential to improve taste. It has also been shown through study to alter gene expression in the colon of colorectal cancer model subjects. This is the labeled isomer. Group: Biochemicals. Alternative Names: BVD Addicrete; Clewat GL; Disparlight DV; EMF 1240; GL-P; GL-P (gluconate); Glonsen; Glucon SGA 60; Gluconic Acid Monosodium Salt; Gluconic Acid Sodium Salt; Helshas A; Monosodium Gluconate; PMP Sodium Gluconate; Pasexon 100T; Resitard P 608A; Sodium D-gluconate; Sodium Gluconate; Sunmorl N 60S; D-Gluconic Acid, Monosodium Salt. Grades: Highly Purified. CAS No. 527-07-1. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C6H11O7Na, Molecular Weight: 218.14. US Biological Life Sciences. | Worldwide |
| SR 2211 | SR 2211 is a selective inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) (Ki = 105 nM; IC50 ~320 nM). SR 2211 exhibits weak activity at liver X receptor α (LXRα) and has no effect on transcriptional activity of farnesoid X receptors (FXR) or transcriptional activity of ROR&alpha. Synonyms: SR-2211; SR2211;SR 2211; 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol; 1,1,1,3,3,3-hexafluoro-2-[3-fluoro-4-[4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol. Grades: ≥98% by HPLC. CAS No. 1359164-11-6. Molecular formula: C26H24F7N3O. Mole weight: 527.48. | |
| Thiazole Orange | Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λ ex = 510 nm (488 nm and 470 nm also show strong excitation) and λ em = 527 nm, respectively [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 107091-89-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-D0150. | |
| Tide FluorTM 2-LL-37 | Dye-labeled LL-37, excitation at 500 nm, emission at 527 nm. Tide FluorTM-2 has an excellent photostability and brightness, and its fluorescence is pH-insensitive. Synonyms: Tide FluorTM 2-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH. Grades: ≥90%. Molecular formula: C205H340N60O53 + dye. Mole weight: 4962. | |
| Tide FluorTM 2-LL-37 (scrambled) | Dye-labeled, scrambled sequence of LL-37, excitation at 500 nm, emission at 527 nm. Tide FluorTM-2 has an excellent photostability and brightness, and its fluorescence is pH-insensitive. ''Scrambled'' means that it contains the same amino acids as LL-37, but in a different order. Synonyms: Tide FluorTM 2-Gly-Leu-Lys-Leu-Arg-Phe-Glu-Phe-Ser-Lys-Ile-Lys-Gly-Glu-Phe-Leu-Lys-Thr-Pro-Glu-Val-Arg-Phe-Arg-Asp-Ile-Lys-Leu-Lys-Asp-Asn-Arg-Ile-Ser-Val-Gln-Arg-OH. Grades: ≥90%. Molecular formula: C205H340N60O53 + dye. Mole weight: 4962. | |
| Tissue plasminogen activator from Human, Recombinant | Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine proteasewhich converts the proenzymeplasminogento plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migrationand tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism. Tissue plasminogen activator human recombinant produced in cho cells is a single, glycosylated polypeptide chain containing 527 amino acids and having a mol...0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. tPA. Mole weight: 59008.71 Da. Activity: 580,000 IU/mg. Stability: Lyophilized t-PA although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution tPA should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Appearance: Sterile Filtered White lyophilized (freeze-dried) powder. Source: CHO. Species: Human. Tissue-type plasminogen activator; EC 3.4.21.68; tPA; t-PA; t-plasminogen activator; TPA; T-PA. Cat No: NATE-0920. | |
| YKL-06-061 | YKL-06-061 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells. Uses: A potential dermatologic drug. Synonyms: YKL06-061; YKL 06-061; YKL-06061. CAS No. 2172617-15-9. Molecular formula: C30H37N7O2. Mole weight: 527.67. | |
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