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| Product | Description | |
|---|---|---|
| Exosome Compound Library | 54 exosome-related compounds that can be used for high-throughput and high-content screening. - Can inhibit or activate the secretion or synthesis of exosomes- Detailed instructions, compound structures, target information, activity descriptions, etc. - NMR and HPLC analytical techniques to ensure high product purity and quality. - All compounds are available in stock. Uses: Scientific use. Product Category: L9420. Categories: Exosome Compounds Libraries. |  |
| Cambinol | Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 ?M and 59 ?M, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14513-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100732. |  |
| Cambinol | Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Uses: Designed for use in research and industrial production. Additional or Alternative Names: cambinol, NSC112546, NSC-112546, SIRT1/2 Inhibitor IV, Cambinol, 14513-15-6, 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, AC1MMYEF, NCIStruc1_001428, NCIStruc2_001159, SureCN3332758, CHEMBL491960, CTK8G3107, HMS3261K21, CCG-37240, DNC009417, NCGC00014121, NCI112546, AKOS002364304, AG-D-88787, CCG-221684. Product Category: Inhibitors. CAS No. 14513-15-6. Molecular formula: C21H16N2O2S. Mole weight: 360.43. Purity: 0.96. IUPACName: 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one. Density: 1.41g/cm³. Product ID: ACM14513156. Alfa Chemistry ISO 9001:2015 Certified. Categories: Campanology. |  |
| Cytochalasin D | Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin - cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Zygosporin A; NSC 209835. CAS No. 22144-77-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6682. | |
| Dexamethasone | Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexadecadrol; Prednisolone F. CAS No. 50-02-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-14648. | |
| Dexamethasone acetate | Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DEXAMETHASONE 21-ACETATE; DexaMethasone 21-Acetate; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-Acetate; Dexamethasone Acetate. Product Category: Inhibitors. Appearance: White or almost white crystalline powder. CAS No. 1177-87-3. Molecular formula: C24H31FO6. Mole weight: 434.5. Purity: 0.99. IUPACName: Dexamethasone-17-acetate. Canonical SMILES: C[C@@]1([C@@]2(O)C(COC(C)=O)=O)[C@](C[C@H]2C)([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C1. Density: 1.3 g/cm³. Product ID: ACM1177873. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dexamethasone acetate | Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone 21-acetate; Hexadecadrol acetate. CAS No. 1177-87-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14648A. | |
| Dexamethasone (Standard) | Dexamethasone (Standard) is the analytical standard of Dexamethasone. This product is intended for research and analytical applications. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexadecadrol(Standard); Prednisolone F (Standard). CAS No. 50-02-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-14648R. | |
| Dexamethasone (Water Soluble) | Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone cyclodextrin complex. CAS No. 50-02-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14648C. | |
| DiD Labeled ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. DiD Labeled ExoLiposome incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. Group: Exoliposome. Categories: Exo Liposomes. |  |
| DiI Labeled ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. DiI Labeled ExoLiposome incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. Group: Exoliposome. Categories: Exo Liposomes. | |
| DiR Labeled ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. DiR Labeled ExoLiposome incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. Group: Exoliposome. Categories: Exo Liposomes. | |
| DPTIP | DPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 351353-48-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131002. | |
| Endosidin-2 | Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ES2. CAS No. 1839524-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120821. | |
| Esomeprazole magnesium | Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H + , K + -ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research [1] [2]. Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H + -ATPases [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Omeprazole magnesium; (-)-Omeprazole magnesium. CAS No. 161973-10-0. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1446. | |
| Esomeprazole magnesium trihydrate | Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally active H + , K + -ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research [1] [2]. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H + -ATPases [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Omeprazole magnesium trihydrate; (-)-Omeprazole magnesium trihydrate. CAS No. 217087-09-7. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-17022. | |
| Esomeprazole sodium | Esomeprazole sodium ((S)-Omeprazole sodium) is a potent and orally active proton pump inhibitor. Esomeprazole reduces acid secretion through inhibition of the H + , K + -ATPase in gastric parietal cells. Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H + -ATPases [4]. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Omeprazole sodium; (-)-Omeprazole sodium. CAS No. 161796-78-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17023. | |
| Fluorescein DHPE Labeled ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. Fluorescein DHPE is a lipid labelled with a green fluorescent pH-sensitive group.This product can be used for measuring lateral diffusion in membranes. Group: Exoliposome. Categories: Exo Liposomes. | |
| Guanosine-5'-triphosphate disodium salt | Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-GTP disodium salt. CAS No. 56001-37-7. Pack Sizes: 250 mg (100 mM * 4.41 mL in Water); 500 mg (100 mM * 8.82 mL in Water); 1 g (100 mM * 17.63 mL in Water). Product ID: HY-W010737. | |
| Guanosine 5'-triphosphate trisodium salt | Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-GTP trisodium salt. CAS No. 36051-31-7. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12695. | |
| GW4869 | GW4869 is a noncompetitive neutral sphingomyelinase (N-SMase) inhibitor with an IC 50 of 1 μM. GW4869 is an inhibitor of exosome biogenesis/release [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6823-69-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-19363. | |
| GW-4869 HCl | GW-4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM). It inhibits TNF-α-mediated sphingomyelin hydrolysis (100% inhibition at 20 μM). GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells. Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GW4869; GW-4869; GW 4869; GW554869A; GW-554869A; GW 554869A; GW69A; GW-69A; GW 69A; GW-4869 HCl. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 6823-69-4. Molecular formula: C30H30Cl2N6O2. Mole weight: 577.51. Purity: >98%. IUPACName: (2E,2'E)-3,3'-(1,4-phenylene)bis(N-(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)acrylamide) dihydrochloride. Canonical SMILES: O=C(/C=C/C1=CC=C(C=C1)/C=C/C(NC2=CC=C(C=C2)C3=NCCN3)=O)NC4=CC=C(C=C4)C5=NCCN5.[H]Cl.[H]Cl. Product ID: ACM6823694-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Heparin | Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Heparinum. Product Category: Inhibitors. CAS No. 9005-49-6. Product ID: ACM9005496. Alfa Chemistry ISO 9001:2015 Certified. | |
| Heparin Lithium salt | Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). Heparin Lithium salt significantly inhibits exosome-cell interactions. Uses: Scientific research. Group: Signaling pathways. CAS No. 9045-22-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17567B. | |
| Heparin sodium salt | Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium heparin; Sodium heparinate. CAS No. 9041-8-1. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-17567A. | |
| Lansoprazole | Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-1749. CAS No. 103577-45-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-13662. | |
| Manumycin A | Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF ?, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion[1][3][4].. Uses: Scientific research. Group: Natural products. CAS No. 52665-74-4. Pack Sizes: 1 mg. Product ID: HY-N6796. | |
| Monensin sodium | Monensin (Monensin A) sodium, an orally active antibiotic , is an ionophore that mediates Na + /H + exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Monensin A sodium. CAS No. 22373-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0150. | |
| Omeprazole | Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria [2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 16868. CAS No. 73590-58-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0113. | |
| Omeprazole | Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine. Product Category: Inhibitors. Appearance: White solid. CAS No. 73590-58-6. Molecular formula: C17H19N3O3S. Mole weight: 345.42. Purity: 99%+. IUPACName: 6-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole. Canonical SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC. Density: 1.332 g/cm³. Product ID: ACM73590586. Alfa Chemistry ISO 9001:2015 Certified. | |
| Omeprazole sodium | Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole sodium shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole sodium also inhibits growth of Gram-positive and Gram-negative bacteria [2]. Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 16868 sodium. CAS No. 95510-70-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0113A. | |
| Omeprazole (Standard) | Omeprazole (Standard) is the analytical standard of Omeprazole. This product is intended for research and analytical applications. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria [2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 73590-58-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0113R. | |
| Plain ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. Group: Exoliposome. Categories: Exo Liposomes. | |
| Rhodamine DHPE Labeled ExoLiposome | The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. Rhodamine DHPE is a glycerophosphoethanolamine lipid labeled with rhodamine. This product can be used in membrane fusion assays. Group: Exoliposome. Categories: Exo Liposomes. | |
| (R)-Lansoprazole | (R)-Lansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexlansoprazole. CAS No. 138530-94-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13662B. | |
| Shikonin | Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC 50 of 6.5 μM [1]. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor [2] and can also inhibit TNF-α and NF-κB pathway [3]. Shikonin decreases exosome secretion through the inhibition of glycolysis [4]. Shikonin inhibits AIM2 inflammasome activation [7]. Uses: Scientific research. Group: Natural products. Alternative Names: C.I. 75535; Isoarnebin 4. CAS No. 517-89-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0822. | |
| Shikonin | Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C.I. 75535. Product Category: Inhibitors. CAS No. 517-89-5. Molecular formula: C16H16O5. Mole weight: 288.3. Purity: 0.98. Product ID: ACM517895. Alfa Chemistry ISO 9001:2015 Certified. | |
| (S)-Lansoprazole | (S)-Lansoprazole (Levolansoprazole) is an isoform of Lansoprazole (HY-13662), which is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Levolansoprazole. CAS No. 138530-95-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13662C. | |
| Sulfisoxazole | Sulfisoxazole (Sulfafurazole) is an orally active endothelin receptor antagonist with IC 50 values of 0.60 μM and 22 μM against endothelin receptor A and endothelin receptor B, respectively. Sulfisoxazole is a sulfonamide antibacterial agent with an oxazole substituent. Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sulfafurazole. CAS No. 127-69-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0323. | |
| Sulfisoxazole (Standard) | Sulfisoxazole (Standard) is the analytical standard of Sulfisoxazole. This product is intended for research and analytical applications. Sulfisoxazole (Sulfafurazole) is an orally active endothelin receptor antagonist with IC 50 values of 0.60 μM and 22 μM against endothelin receptor A and endothelin receptor B, respectively. Sulfisoxazole is a sulfonamide antibacterial agent with an oxazole substituent. Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127-69-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0323R. | |
| Tunicamycin | Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity[1][2][3].Tunicamycin increases exosome release in cervical cancer cells[4]. Uses: Scientific research. Group: Natural products. CAS No. 11089-65-9. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-A0098. | |
| Tunicamycin | Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.Tunicamycin increases exosome release in cervical cancer cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: tunicamycin, Tunicamycin A1, CID5607, 11089-65-9. Product Category: Inhibitors. Appearance: White to off-white powder. CAS No. 11089-65-9. Molecular formula: C37H60N4O16. Mole weight: 816.89. Purity: 98%+. IUPACName: N-[2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[2-[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-4,5-dihydroxyoxan-3-yl]-12-methyltridec-2-enamide. Canonical SMILES: CC(C)CCCCCCCCC=CC(=O)NC1C(C(C(OC1OC2C(C(C(C(O2)CO)O)O)NC(=O)C)CC(C3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O)O)O. Density: 1.57g/cm³. Product ID: ACM11089659. Alfa Chemistry ISO 9001:2015 Certified. | |
| Adenosylhomocysteinase | Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SAHH; AHCY. CAS No. 9025-54-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149048. | |
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