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1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H21F2NO3. CAS No. 163222-33-1. Prepack ID 74798364-1g. Molecular Weight 409.4. See USA prepack pricing.
Ezetimibe
Ezetimibe. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, sch-58235. Grades: Highly Purified. CAS No. 163222-33-1. Pack Sizes: 10mg, 25mg, 100mg, 250mg, 500mg. Molecular Formula: C24H21F2NO3. US Biological Life Sciences.
Worldwide
Ezetimibe
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 58235. CAS No. 163222-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17376.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L26) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(2-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Ezetimibe 3-Fluoro Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L27) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
An antihyperlipoproteinem ic. A Cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235. Grades: Highly Purified. CAS No. 163222-33-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ezetimibe Aniline Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L28) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4-Dehydroxy-4-amino Ezetimibe; (3R,4S)-4-(4-Aminophenyl)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-2-azetidinone. Grades: > 95%. CAS No. 1354716-98-5. Molecular formula: C24H22F2N2O2. Mole weight: 408.45.
Ezetimibe Azetidinone (Ring-opened Impurity)
A degradation product of the antihyperlipoproteinem ic Ezetimibe. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ezetimibe Azetidinone Ring-opened Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L8) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Azetidinone Ring-opened Sodium Salt Impurity (Technical Grade, >75%). Grades: > 95%. CAS No. 1391053-63-6. Molecular formula: C24H23F2NO4. Mole weight: 427.45.
A metabolite of Ezetimibe, an antihyperlipoproteinem ic. A Cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: Ezetimibe Phenoxy Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ezetimibe Benzyl Impurity (MBZT-2)
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L32) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-(3-(benzyloxy)-3-(4-fluorophenyl)propyl)-1-(3-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 851860-29-2. Molecular formula: C31H27F2NO3. Mole weight: 499.56.
Ezetimibe-d4
Ezetimibe-d 4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SCH 58235-d4. CAS No. 1093659-90-5. Pack Sizes: 1 mg. Product ID: HY-17376S.
Labeled Ezetimibe, an antihyperlipoproteinem ic. A Cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ezetimibe-d4 β-D-Glucuronide
Phase-II labeled metabolite of Ezetimibe, an antihyperlipoproteinem ic. A cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid; Ezetimibe-d4 Phenoxy Glucuronide; Sch 58235-d4 Glucuronide; Sch 60663-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ezetimibe-d4 Diacetate
A derivative of 2-azetidinone with antihyperlipoproteinem ic properties. Group: Biochemicals. Alternative Names: (3R,4S)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ezetimibe Dehydoxy Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-Dehydroxy Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 204589-58-2. Molecular formula: C24H21F2NO2. Mole weight: 393.44.
Ezetimibe Deprotected Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L13) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: ((S)-3-{(2R, 5S)-5-(4-Fluorophenyl)-2-[(S)-(4-Fluorophenylamino)-(4-OH-phenyl)methyl]-5-O. Grades: > 95%. CAS No. 1185883-40-2. Molecular formula: C33H30F2N2O5. Mole weight: 572.61.
Ezetimibe Desfluoro Chloro Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L29) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe; (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H21ClFNO3. Mole weight: 425.89.
Ezetimibe Desfluoro Dehydoxy Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L45) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-((S)-3-(benzyloxy)-3-(4-fluorophenyl)propyl)-1-(3-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H22FNO2. Mole weight: 375.45.
Ezetimibe Desfluoro Methyl Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4"DeFluoro-4"methyl-ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.47.
Ezetimibe-D-glucuronide D4
Ezetimibe-D-glucuronide D4 is an esteemed compound in the biomedical field, aiding in the research of hypercholesterolemia and familial hypercholesterolemia. Manifesting as a remarkable cholesterol absorption inhibitor, it deftly curtails cholesterol levels through the hindrance of intestinal cholesterol assimilation and associated phytosterol uptake. Synonyms: Ezetimibe-d4 β-D-Glucuronide. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57.
Ezetimibe Diacetate
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L5) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-4-[4-(acetyloxy)phenyl]-1-(4-fluorophenyl)-2-azetidinone. Grades: > 95%. CAS No. 163380-20-9. Molecular formula: C28H25F2NO5. Mole weight: 493.51.
Ezetimibe Diacetate
Protected Ezetimibe derivative. Group: Biochemicals. Alternative Names: (3R,4S)-. Grades: Highly Purified. CAS No. 163380-20-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ezetimibe (Diacid Impurity)
An open-ringed diacid impurity of Ezetimibe. Group: Biochemicals. Alternative Names: (2R) -2- [ (S) - [ (4-Fluorophenyl) amino] [4- (phenylmethoxy) phenyl] methyl] pentanedioic Acid. Grades: Highly Purified. CAS No. 1013025-04-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ezetimibe Diacid Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: ( (2R, 3S) -2-[ (4-Benzyloxyphenyl) -4- (4-Fluorophenylamino) methyl]pentanedioic acid). Grades: > 95%. CAS No. 1013025-04-1. Molecular formula: C25H24FNO5. Mole weight: 437.47.
Ezetimibe Diol
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L22) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (1S,4R)-1-(4-Fluorophenyl)-4-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-1,5-pentanediol. Grades: > 95%. CAS No. 1374250-08-4. Molecular formula: C24H25F2NO3. Mole weight: 413.47.
Ezetimibe Fluoro Isomer
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-(2-Fluorophenyl) Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 1798008-25-9. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Ezetimibe hydroxy-D-glucuronide D4
Ezetimibe hydroxy-D-glucuronide D4 is a metabolite of stable isotope-labeled Ezetimibe, playing a profound role in illuminating the intricate mechanisms of Ezetimibe metabolism, pharmacokinetics and elimination pathways. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57.
Ezetimibe Hydroxy Glucuronide
A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Hydroxy β-D-Glucuronide; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 536709-33-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55.
Ezetimibe Hydroxy tert-Butyldiphenylsilyl Ether
Ezetimibe Hydroxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-tert-butyldiphenylsilyloxy-3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: Highly Purified. CAS No. 1217748-67-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ezetimibe Impuriry 66
Ezetimibe Impuriry 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1044664-24-5. Molecular formula: C26H23F2NO4. Mole weight: 451.47. Catalog: APB1044664245.
Ezetimibe Impuriry 74
Ezetimibe Impuriry 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-73-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564739.
Ezetimibe Impuriry 75
Ezetimibe Impuriry 75. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1416263-36-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1416263369.
Ezetimibe Impuriry 82
Ezetimibe Impuriry 82. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-75-1. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564751.
Ezetimibe Impurity 10
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L44) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C18H18FNO3. Mole weight: 315.35.
Ezetimibe Impurity 2
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56.
Ezetimibe Impurity 3
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L18) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-1-phenylazetidin-2-one. Grades: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L38) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L36) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. Grades: > 95%. CAS No. 528565-93-7. Molecular formula: C20H20FNO4. Mole weight: 357.39.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L37) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. CAS No. 189028-95-3. Molecular formula: C20H20FNO4. Mole weight: 357.39.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L39) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39.
Ezetimibe Impurity 38
Ezetimibe Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-((2R,5S)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-5-(4-fluorophenyl)pentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1701462-59-0. Molecular formula: C45H58F2N2O5Si2. Mole weight: 801.12. Catalog: APB1701462590.
Ezetimibe Impurity 39
Ezetimibe Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-hydroxybenzaldehyde. CAS No. 123-08-0. Molecular formula: C7H6O2. Mole weight: 122.12. Catalog: APB123080.
Ezetimibe Impurity 4
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L19) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3S,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H25F2NO3. Mole weight: 497.55.
Ezetimibe Impurity 49
Ezetimibe Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dihydro-2H-pyran-2,6(3H)-dione. CAS No. 108-55-4. Molecular formula: C5H6O3. Mole weight: 114.1. Catalog: APB108554.
Ezetimibe Impurity 5
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L20) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H27F2NO3. Mole weight: 499.56.
Ezetimibe Impurity 8
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L42) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Grades: > 95%. CAS No. 189028-93-1. Molecular formula: C20H18FNO4. Mole weight: 355.37.
Ezetimibe Impurity 8 Enantiomer
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L46) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone. Grades: > 95%. CAS No. 404874-93-7. Molecular formula: C20H18FNO4. Mole weight: 355.37.
Ezetimibe Impurity 9
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. Grades: > 95%. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98.
Ezetimibe Impurity B
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L14) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: methyl 5-(4-fluorophenyl)-5-hydroxypentanoate. Grades: > 95%. CAS No. 870634-36-9. Molecular formula: C12H15FO3. Mole weight: 226.25.
Ezetimibe Impurity G
Ezetimibe Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB1700622065.
Ezetimibe Impurity I
Ezetimibe Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.46. Catalog: APB1700622076.
Ezetimibe Impurity J
Ezetimibe Impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-08-7. Molecular formula: C24H21ClFNO3. Mole weight: 425.88. Catalog: APB1700622087.
Ezetimibe Impurity L
Ezetimibe Impurity L. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide. CAS No. 1510820-22-0. Molecular formula: C24H23F2NO2. Mole weight: 395.44. Catalog: APB1510820220.
Ezetimibe Impurity (Tetrahydro-pyran-2-one)
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L35) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,6R)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Ezetimibe ketone
Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114.
Ezetimibe ketone
Ezetimibe ketone. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K. Grades: Highly Purified. CAS No. 191330-56-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H19F2NO3. US Biological Life Sciences.
Worldwide
Ezetimibe Ketone
Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42.
Ezetimibe Lactam Cleaved Alcohol
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L23) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-Anhydro Ezetimibe Alcohol Impurity; (βR,γS)-γ-[(4-Fluorophenyl)amino]-β-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanol. Grades: > 95%. CAS No. 1374250-07-3. Molecular formula: C24H23F2NO2. Mole weight: 395.45.
Ezetimibe Phenexy Glucuronide
A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe phenoxy Glucuronide. Grades: > 95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55.
Ezetimibe phenoxy glucuronide
Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity [1]. Ezetimibe is a potent cholesterol absorption inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135391.
Ezetimibe Phenoxy tert-Butyldiphenylsilyl Ether
Ezetimibe Phenoxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R, 4S) -1- (4-Fluorophenyl ) -3- [ (3S) -3- (4-fluorophenyl ) -3- hydroxypropyl ] -4- (4-tert-butyl diphenyl silyl oxyphenyl ) -2-azetidinone. Grades: Highly Purified. CAS No. 1042722-66-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ezetimibe Related Impurity 6
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L40) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Ezetimibe Related Impurity 7
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L41) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((E)-3-(3-fluorophenyl)allyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 204589-68-4. Molecular formula: C24H19F2NO2. Mole weight: 391.42.
Ezetimibe Ring-Open Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grades: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45.
Ezetimibe ring-opening dehydrate impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grades: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Ezetimibe System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ezetimibe Tetrahydropyran Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide; SCH59566. Grades: > 95%. CAS No. 1296129-15-1. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
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