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Fingolimod (FTY720 free base) is a sphingosine 1-phosphate ( S1P ) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 free base. CAS No. 162359-55-9. Pack Sizes: 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-11063.
Fingolimod-d4
Fingolimod-d 4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720 free based-d4. CAS No. 1346747-38-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-11063S.
Fingolimod-d4 hydrochloride
Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1.
Fingolimod Dimer Impurity
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod; 2-((1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)amino)-4-(4-octylphenyl)butanoic Acid. Grades: > 95%. Molecular formula: C37H59NO4. Mole weight: 581.89.
Fingolimod Heptyl Impurity
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-amino-2-[2-(4-heptylphenyl)?ethyl]?-1,?3-Propanediol. Grades: > 95%. CAS No. 745767-97-9. Molecular formula: C18H31NO2. Mole weight: 293.45.
Fingolimod Hexyl Impurity
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-amino-2-[2-(4-hexyphenyl)?ethyl]?-1,?3-Propanediol. Grades: > 95%. Molecular formula: C17H29NO2. Mole weight: 279.43.
Fingolimod hydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H33NO2 · HCl. CAS No. 162359-56-0. Prepack ID 38561742-1g. Molecular Weight 343.93. See USA prepack pricing.
Fingolimod hydrochloride
Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005.
Fingolimod hydrochloride
Fingolimod hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FTY720. Appearance: White powder. CAS No. 162359-56-0. Molecular formula: C19H34ClNO2. Mole weight: 343.93. Purity: 0.98. IUPACName: 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol;hydrochloride. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl. Product ID: ACM162359560. Alfa Chemistry ISO 9001:2015 Certified.
Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Fingolimod Impurity 1
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Deshydroxymethyl Carboxyethyl N,O-Diacetyl Fingolimod; Ethyl 2-Acetamido-2-(acetoxymethyl)-4-(4-octylphenyl)butanoate. Grades: > 95%. Molecular formula: C25H39NO5. Mole weight: 433.59.
Fingolimod Impurity 10
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 1-(1-iodoethyl)-4-octylbenzene. Grades: > 95%. Molecular formula: C16H25I. Mole weight: 344.28.
Fingolimod Impurity 11
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-Amino-2-[2-(4-pentylphenyl)?ethyl]?-1,?3-propanediol Hydrochloride. Grades: > 95%. Molecular formula: C16H27NO2 HCl. Mole weight: 265.40 36.46.
Fingolimod Impurity 11
Fingolimod Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)palmitamide. CAS No. 1242271-26-6. Molecular formula: C35H63NO3. Mole weight: 545.88. Catalog: APB1242271266.
Fingolimod impurity 12
Fingolimod impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1404233-80-2. Molecular formula: C20H36ClNO2. Mole weight: 357.96. Catalog: APB1404233802.
Fingolimod Impurity 12
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: β-amino-4-octyl- Benzenebutanol. Grades: > 95%. CAS No. 177260-59-2. Molecular formula: C18H31NO. HCl. Mole weight: 277.45 36.46.
Fingolimod Impurity 13
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Benzenebutanoic acid, α-amino-α-(hydroxymethyl)?-4-octyl-, ethyl ester. Grades: > 95%. CAS No. 882691-14-7. Molecular formula: C21H35NO3. Mole weight: 349.51.
Fingolimod Impurity 14
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 3-amino-3-(hydroxymethyl)?-1-(4-octylphenyl)?- 1,?4-Butanediol. Grades: > 95%. CAS No. 162361-49-1. Molecular formula: C19H33NO3. Mole weight: 323.48.
Fingolimod impurity 15
Fingolimod impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 168560-42-7. Molecular formula: C18H32ClNO. Mole weight: 313.91. Catalog: APB168560427.
Fingolimod Impurity 2
An intermediate in the synthesis of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-[1,?1-bis(hydroxymethyl)?-3-(4-octylphenyl)?propyl]?-Acetamide. Grades: > 95%. CAS No. 249289-10-9. Molecular formula: C21H35NO3. Mole weight: 349.52.
Fingolimod Impurity 3
Cas No. 162358-08-9.
Fingolimod Impurity 4
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-Acetyl Deshydroxymethyl Fingolimod; Fingolimod Impurity; N-[1-(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide. Grades: > 95%. CAS No. 177259-52-8. Molecular formula: C20H33NO2. Mole weight: 319.49.
Fingolimod Impurity 5
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: anedioic acid, 2-(acetylamino)?-2-[2-(4-octylphenyl)?-2-oxoethyl]?-, 1,?3-diethyl ester. Grades: > 95%. CAS No. 268557-49-9. Molecular formula: C25H37NO6. Mole weight: 447.58.
Fingolimod Impurity 6
Cas No. 899822-99-2.
Fingolimod Impurity 7
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-Nitrodeamino Fingolimod; 2-Nitro-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol. Grades: > 95%. CAS No. 374077-88-0. Molecular formula: C19H31NO4. Mole weight: 337.46.
Fingolimod Impurity 8
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 1-(2-Iodoethyl)?-2-octylbenzene. Grades: > 95%. CAS No. 162358-96-5. Molecular formula: C16H25I. Mole weight: 344.28.
Fingolimod Impurity 9
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: ortho-Fingolimod; 2-Amino-2-(2-octylphenethyl)propane-1,3-diol. Grades: > 95%. CAS No. 767262-51-1. Molecular formula: C19H33NO2. Mole weight: 307.48.
Fingolimod Impurity A
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-amino-2-[2-[4-(2-hydroxyoctyl)?phenyl]?ethyl]?-1,?3-Propanediol hydrochloride. Grades: > 95%. CAS No. 1343408-33-2. Molecular formula: C19H33NO3. Mole weight: 323.48 36.46.
Fingolimod impurity C
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: α-amino-α-(hydroxymethyl)?-4-octyl- Benzenebutanoic acid. Grades: > 95%. CAS No. 296282-46-7. Molecular formula: C19H31NO3. Mole weight: 321.46.
Fingolimod Methyl Impurity
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-(methylamino)?-2-[2-(4-octylphenyl)?ethyl]?-1,?3-Propanediol. Grades: > 95%. CAS No. 162361-47-9. Molecular formula: C20H35NO2. Mole weight: 321.51.
Fingolimod Palmitate Amide
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-(1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)palmitamide. Grades: > 95%. CAS No. 1242271-26-6. Molecular formula: C35H63NO3. Mole weight: 545.90.
Fingolimod phosphate
Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 phosphate. CAS No. 402615-91-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15381.
Fingolimod Phosphate HCl
A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grades: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46.
Fingolimod (Standard)
Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162359-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11063R.
Fingolimod Stearate Amide
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-(1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)stearamide. Grades: > 95%. CAS No. 1242271-27-7. Molecular formula: C37H67NO3. Mole weight: 573.95.
1-Hydroxy-3-nitrodeamino Fingolimod
An impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 899822-99-2. Pack Sizes: 25mg, 250mg. Molecular Formula: C19H31NO5, Molecular Weight: 353.45. US Biological Life Sciences.
Worldwide
1-Hydroxy Fingolimod Hydrochloride
1-Hydroxy Fingolimod Hydrochloride is an impurity of the drug Fingolimond (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 268557-51-3. Pack Sizes: 1mg, 10mg. Molecular Formula: C19H33NO3 HCl, Molecular Weight: 323.473645999999. US Biological Life Sciences.
Worldwide
2-(4-Octylphenethyl)-fingolimod
2-(4-Octylphenethyl)-fingolimod is an impurity of the drug Fingolimod hydrochloride (F805000), an immunosuppressive agent that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 851039-25-3. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C35H57NO2, Molecular Weight: 523.83. US Biological Life Sciences.
Worldwide
2-Dimethylamino Fingolimod
An impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1404433-87-9. Pack Sizes: 25mg, 250mg. Molecular Formula: C21H37NO2, Molecular Weight: 335.52. US Biological Life Sciences.
Worldwide
2-Nitrodeamino Fingolimod
An impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 374077-88-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C19H31NO4, Molecular Weight: 337.45. US Biological Life Sciences.
Worldwide
3-(4-Octylphenethyl)-fingolimod
3-(4-Octylphenethyl)-fingolimod is a related compound of the drug Fingolimod hydrochloride (F805000), an immunosuppressive agent that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 851039-24-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C34H56ClNO2, Molecular Weight: 546.27. US Biological Life Sciences.
Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when phosphorylated by sphingosine kinase. Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 activity enhancer. Cytosolic phospholipase A2 inhibitor, independent of sphingosine 1-phosphate receptors. Autophagy inducer. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences.
Worldwide
N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod
N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002417. Format: Neat.
N-Ethyl Fingolimod
An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-(ethylamino)?-2-[2-(4-octylphenyl)?ethyl]?-1,?3-Propanediol. Grades: > 95%. CAS No. 1402793-28-5. Molecular formula: C21H37NO2. Mole weight: 335.53.
2,2'-((4-Octyl-1,3-phenylene)bis(ethane-2,1-diyl))bis(2-aminopropane-1,3-diol) Dihydrochloride is a related compound of the drug Fingolimod hydrochloride (F805000), an immunosuppressive agent that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H46Cl2N2O4, Molecular Weight: 497.54. US Biological Life Sciences.
2,2-Dimethyl-5-[2-(4-octylphenyl)ethyl]-1,3-dioxan-5-amine is an intermediate in the synthesis of N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod,which is an impurity of Fingolimod (F805000, HCl salt). Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1313876-85-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H37NO2. US Biological Life Sciences.
Worldwide
2-[4- (1-Hydroxyoctyl) phenyl]ethyl Acetate
2-[4- (1-Hydroxyoctyl) phenyl]ethyl Acetate is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H28O3, Molecular Weight: 292.41. US Biological Life Sciences.
Worldwide
2-[4-(Oct-1-en-yl)phenyl]ethyl Acetate
2-[4-(Oct-1-en-yl)phenyl]ethyl Acetate is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H26O2, Molecular Weight: 274.399999999999. US Biological Life Sciences.
2-Amino-2-[2-(4-decylphenyl)ethyl]-1,3-propanediol is used for treating, preventing or delaying the progression of multiple sclerosis in a pediatric patient. 2-Amino-2-[2-(4-decylphenyl)ethyl]-1,3-propanediol is also a FIngolimod (F342045) impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 780729-32-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H37NO2, Molecular Weight: 335.52. US Biological Life Sciences.
2-Amino-2-[2- (4-heptylphenyl) ethyl]propane-1, 3-diol is an impurity of Fingolimod (F342045), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 745767-97-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H31NO2, Molecular Weight: 293.44. US Biological Life Sciences.
2-Amino-2-[2-(4-hexylphenyl)ethyl]-1,3-propanediol is used for treating, preventing or delaying the progression of multiple sclerosis in a pediatric patient. 2-Amino-2-[2-(4-hexylphenyl)ethyl]-1,3-propanediol is also a FIngolimod (F342045) impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1201794-93-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C17H29NO2, Molecular Weight: 279.42. US Biological Life Sciences.
2-Amino-2-[2-(4-nonylphenyl)ethyl]-1,3-propanediol is an impurity of Fingolimod (F342045), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. CAS No. 746594-44-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H35NO2, Molecular Weight: 321.5. US Biological Life Sciences.
Worldwide
2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol
2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol. Group: Biochemicals. Alternative Names: Fingolimod; FTY720. Grades: Highly Purified. CAS No. 162359-55-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C19H33NO2. US Biological Life Sciences.
Worldwide
3-Amino-1-(4-octylphenyl)butane-1,4-diol
3-Amino-1-(4-octylphenyl)butane-1,4-diol is a related compound of the drug Fingolimod hydrochloride (F805000), an immunosuppressive agent that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C18H31NO2, Molecular Weight: 293.44. US Biological Life Sciences.
Worldwide
Amiselimod hydrochloride
Amiselimod (MT-1303) hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod hydrochloride is an orally active and high selectivity sphingosine 1-phosphate receptor-1 ( S1P1 ) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod hydrochloride inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimod hydrochloride is promising for research of autoimmune diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-1303 hydrochloride. CAS No. 942398-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16734A.
azido-FTY720
Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibits lymphocyte egress from lymphoid tissues by down-regulating sphingosine-1 phosphate receptor (S1PR). Phosphorylation of FTY270 by sphingosine kinase can cause S1P1R internalization, which sequesters lymphocytes in lymph nodes, preventing them from taking part in an autoimmune response. It is a first-in-class orally bioavailable compound that has shown efficacy in advanced clinical trials for the treatment of multiple sclerosis (MS). Synonyms: azido-FTY720; 881914-35-8; 2-Amino-2-[2-(3-azido-4-octylphenyl)ethyl]-1,3-propanediol; 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol; 1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]-; AKOS040755896; HY-134976; CS-0168486. Grades: ≥98%. CAS No. 881914-35-8. Molecular formula: C19H32N4O2. Mole weight: 348.5.
FTY720 Hydrochloride
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). Group: Biochemicals. Alternative Names: 2-Amino-2- (2- (4-octylphenyl) ethyl) propane-1, 3-diol Hydrochloride; Fingolimod Hydrochloride. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Fty720(R)-phosphate
Fty720(R)-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: fingolimod-P; FTY720-P; FTY720-phosphate,rac-2; FTY720 phosphate. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 402616-23-3. Molecular formula: C19H34NO5P. Mole weight: 387.5. Purity: ≥98%. IUPACName: [2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(COP(=O)(O)O)N. Product ID: ACM402616233. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fingolimod phosphate.
GSK-2262167 hydrate
GSK-2262167 is a potent S1P3-sparing and S1P1 agonist and has a potent activity is in a collagen-induced arthritis model as efficacious as fingolimod and shows excellent pharmacokinetic properties preclinically. Uses: Arthritis. Synonyms: GSK-2262167 sodium; GSK 2262167 sodium; GSK2262167 sodium; sodium 3-(6-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-5-methyl-3,4-dihydroisoquinolin-2(1H)-yl)propanoate. Grades: ≥98%. CAS No. 1458576-13-0. Molecular formula: C25H28N4O5. Mole weight: 464.51.
GSK-2262167 sodium
This molecular is a potent S1P3-sparing and S1P1 agonist. Meanwhile GSK-2262167 has a potent activity is in a collagen-induced arthritis model as efficacious as fingolimod and shows excellent pharmacokinetic properties preclinically. Uses: Arthritis. Synonyms: GSK-2262167 sodium; GSK 2262167 sodium; GSK2262167 sodium; sodium 3-(6-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-5-methyl-3,4-dihydroisoquinolin-2(1H)-yl)propanoate,1165924-28-6 (free acid); 458576-13-0 (hydrate). Grades: 98%. CAS No. 1165923-54-5. Molecular formula: C25H25N4NaO4. Mole weight: 468.49.
rac FTY720 Phosphate
rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Group: Biochemicals. Alternative Names: 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate); 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester; FTY720-P; FTY-P; Fingolimod phosphate. Grades: Highly Purified. CAS No. 402615-91-2. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
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