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Fingolimod phosphate Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 phosphate. CAS No. 402615-91-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15381. MedChemExpress MCE
Fingolimod Phosphate HCl A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grades: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46. BOC Sciences 8
Amiselimod hydrochloride Amiselimod (MT-1303) hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod hydrochloride is an orally active and high selectivity sphingosine 1-phosphate receptor-1 ( S1P1 ) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod hydrochloride inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimod hydrochloride is promising for research of autoimmune diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-1303 hydrochloride. CAS No. 942398-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16734A. MedChemExpress MCE
azido-FTY720 Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibits lymphocyte egress from lymphoid tissues by down-regulating sphingosine-1 phosphate receptor (S1PR). Phosphorylation of FTY270 by sphingosine kinase can cause S1P1R internalization, which sequesters lymphocytes in lymph nodes, preventing them from taking part in an autoimmune response. It is a first-in-class orally bioavailable compound that has shown efficacy in advanced clinical trials for the treatment of multiple sclerosis (MS). Synonyms: azido-FTY720; 881914-35-8; 2-Amino-2-[2-(3-azido-4-octylphenyl)ethyl]-1,3-propanediol; 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol; 1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]-; AKOS040755896; HY-134976; CS-0168486. Grades: ≥98%. CAS No. 881914-35-8. Molecular formula: C19H32N4O2. Mole weight: 348.5. BOC Sciences
Fingolimod Fingolimod (FTY720 free base) is a sphingosine 1-phosphate ( S1P ) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 free base. CAS No. 162359-55-9. Pack Sizes: 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-11063. MedChemExpress MCE
Fingolimod-d4 Fingolimod-d 4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720 free based-d4. CAS No. 1346747-38-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-11063S. MedChemExpress MCE
Fingolimod-d4 hydrochloride Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1. MedChemExpress MCE
Fingolimod hydrochloride Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005. MedChemExpress MCE
Fingolimod Hydrochloride (FTY-720A, FTY720, D04187, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Hydrochloride) Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 1
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Fingolimod (Standard) Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162359-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11063R. MedChemExpress MCE
Fty720(R)-phosphate Fty720(R)-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: fingolimod-P; FTY720-P; FTY720-phosphate,rac-2; FTY720 phosphate. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 402616-23-3. Molecular formula: C19H34NO5P. Mole weight: 387.5. Purity: ≥98%. IUPACName: [2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(COP(=O)(O)O)N. Product ID: ACM402616233. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Fingolimod phosphate. Alfa Chemistry. 3
rac FTY720 Phosphate rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Group: Biochemicals. Alternative Names: 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate); 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester; FTY720-P; FTY-P; Fingolimod phosphate. Grades: Highly Purified. CAS No. 402615-91-2. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. USBiological 2
Worldwide
FTY720 Hydrochloride (Gilenya, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol. HCl, Fingolimod) Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when phosphorylated by sphingosine kinase. Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 activity enhancer. Cytosolic phospholipase A2 inhibitor, independent of sphingosine 1-phosphate receptors. Autophagy inducer. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. USBiological 4
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