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| Product | Description | |
|---|---|---|
| Flagellin | Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4). Group: Others. Synonyms: FliC. Purity: >=90% (SDS-PAGE). Stability: Stable for at least 6 months after receipt when stored at -20°C. Storage: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Form: Lyophilized. Contains PBS. Source: Salmonella typhimurium strain 14028. FliC; Flagellin. Cat No: LIGC-004. |  |
| Flagelin 22 | Flagelin 22 is a fragment of bacterial flagellin, which is an effective elicitor in both plants and algae. Synonyms: Flagellin 22; L-Alanine, L-glutaminyl-L-arginyl-L-leucyl-L-seryl-L-threonylglycyl-L-seryl-L-arginyl-L-isoleucyl-L-asparaginyl-L-seryl-L-alanyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-alanyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-isoleucyl-; Gln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala. Grade: ≥95%. CAS No. 304642-91-9. Molecular formula: C93H162N32O34. Mole weight: 2272.48. |  |
| Flagelin 22 TFA | Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Flagellin 22 TFA. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1568A. |  |
| Flagelin 22 TFA | Flagelin 22 TFA is a fragment of bacterial flagellin, which is an effective elicitor in both plants and algae. Synonyms: Flagellin 22 (TFA); L-Alanine, L-glutaminyl-L-arginyl-L-leucyl-L-seryl-L-threonylglycyl-L-seryl-L-arginyl-L-isoleucyl-L-asparaginyl-L-seryl-L-alanyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-alanyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-isoleucyl-, trifluoroacetic acid; Gln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala.TFA; Flagellin 22 trifluoroacetic acid. Grade: ≥98%. Molecular formula: C93H162N32O34.C2HF3O2. Mole weight: 2386.49. | |
| TH1020 | TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 ?M. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1841460-82-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116961. | |
| UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) | Contains NADP+ as a cofactor. This is the first enzyme in the biosynthetic pathway of pseudaminic acid, a sialic-acid-like sugar that is unique to bacteria and is used by Helicobacter pylori to modify its flagellin. This enzyme plays a critical role in H. pylori's pathogenesis, being involved in the synthesis of both functional flagella and lipopolysaccharides. It is completely inhibited by UDP-α-D-galactose. The reaction results in the chirality of the C-5 atom being inverted. It is thought that Lys-133 acts sequentially as a catalytic acid, protonating the C-6 hydroxy group and as a catalytic base, abstracting the C-5 proton, resulting in the elimination of water. This enzyme belongs to the short-chain dehydrogenase/reductase family of enzymes. Group: Enzymes. Synonyms: FlaA1; UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase; PseB; UDP-N-acetylglucos. Enzyme Commission Number: EC 4.2.1.115. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4955; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting); EC 4.2.1.115; FlaA1; UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase; PseB; UDP-N-acetylglucosamine hydro-lyase (inverting; UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose-forming). Cat No: EXWM-4955. | |
| UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) | Requires Mg2+. Involved in biosynthesis of legionaminic acid, a nonulosonate derivative that is incorporated by some bacteria into assorted virulence-associated cell surface glycoconjugates. The initial product formed by the enzyme from Legionella pneumophila, which incorporates legionaminic acid into the O-antigen moiety of its lipopolysaccharide, is 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose, which rapidly mutarotates to a mixture of anomers. The enzyme from Campylobacter jejuni, which incorporates legionaminic acid into flagellin, prefers GDP-N,N'-diacetylbacillosamine. Group: Enzymes. Synonyms: UDP-Bac2Ac4Ac 2-epimerase; NeuC. Enzyme Commission Number: EC 3.2.1.184. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3868; UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing); EC 3.2.1.184; UDP-Bac2Ac4Ac 2-epimerase; NeuC. Cat No: EXWM-3868. | |
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