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| Product | Description | |
|---|---|---|
| 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole. Group: Biochemicals. Alternative Names: 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide; ABD-F. Grades: Highly Purified. CAS No. 91366-65-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C6H4FN3O3S. US Biological Life Sciences. |  Worldwide |
| 4-(Chlorosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 4-(Chlorosulfonyl)-7-fluoro-2,1,3-benzoxadiazole. Group: Biochemicals. Alternative Names: 7-Fluoro-4-benzofurazansulfonyl chloride. Grades: Highly Purified. CAS No. 91366-64-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C6H2ClFN2O3S. US Biological Life Sciences. | Worldwide |
| 4-Fluoro-2,1,3-benzoxadiazole | 4-Fluoro-2,1,3-benzoxadiazole. Group: Biochemicals. Alternative Names: 4-Fluorobenzofurazan; 4-Fluoro-2,1,3-benzoxadiazole. Grades: Highly Purified. CAS No. 29270-55-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C6H3FN2O. US Biological Life Sciences. | Worldwide |
| 4-Fluoro-7-nitrobenzofurazan | 4-Fluoro-7-nitrobenzofurazan. Group: Biochemicals. Alternative Names: 4-Fluoro-7-nitro-2,1,3-benzoxadiazole. Grades: Highly Purified. CAS No. 29270-56-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C6H2FN3O3. US Biological Life Sciences. | Worldwide |
| NBD-amine | Other Fluorophores. Alternative Names: 7-Amino-NBD,7-Amino-4-nitro-2,1,3-benzoxadiazole,7-Nitro-4-aminobenzofurazan,ABF. CAS No. 10199-91-4. Molecular formula: C6H4N4O3. Mole weight: 180.12. Appearance: Orange to brown powde. Purity: 99%+. IUPACName: 4-nitro-2,1,3-benzoxadiazol-7-amine. Canonical SMILES: C1=C(C2=NON=C2C(=C1)[N+](=O)[O-])N. Catalog: ACM10199914-1. |  |
| NBD-azide | Other Fluorophores. Alternative Names: 4-Azido-7-nitrobenzofurazan,4-Azido-7-nitro-2,1,3-benzoxadiazole. CAS No. 10199-90-3. Molecular formula: C6H2N6O3. Mole weight: 206.12. Appearance: Yellow crystalline powder. Purity: 99%+. IUPACName: 7-azido-4-nitro-2,1,3-benzoxadiazole. Canonical SMILES: C1=C (C2=NON=C2C (=C1)[N+] (=O)[O-])N=[N+]=[N-]. Catalog: ACM10199903-1. | |
| NBD-Cl | Other Fluorophores. Alternative Names: 4-Chloro-7-nitrobenzofurazan. CAS No. 10199-89-0. Molecular formula: C6H2ClN3O3. Mole weight: 199.55. Appearance: Yellow to light brown crystalline powder. Purity: 95%+. IUPACName: 4-chloro-7-nitro-2,1,3-benzoxadiazole. Canonical SMILES: C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]. Density: 2.0589 g/ml. Catalog: ACM10199890-1. | |
| 6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH2 | It is an excellent fluorogenic substrate for matrix metalloproteinase stromelysin (MMP-3) hydrolysis. The FRET substrate shows high sensitivity and improves accuracy at a lower substrate turnover. It has a kcat/Km value of 2.14ยท104 M-1s-1 and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore, it is a suitable tool for high-throughput inhibitor screening. Synonyms: NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH2; L-Lysinamide, N2-[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-1-oxohexyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-leucyl-L-alanyl-L-norvalyl-L-tryptophyl-N6-[2-[7-(dimethylamino)-2-oxo-2H-1-benzopyran-4-yl]acetyl]-; NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH2; N2-{6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-leucyl-L-alanyl-L-norvalyl-L-tryptophyl-N6-{[7-(dimethylamino)-2-oxo-2H-chromen-4-yl]acetyl}-L-lysinamide. Grades: ≥95%. CAS No. 945414-97-1. Molecular formula: C78H111N21O16. Mole weight: 1598.87. |  |
| HIF Inhibitor VII (Hypoxia-Inducible Factor Inhibitor VI, N-(3-Chloro-5-fluorophenyl)-4-nitrobenzo[c][1, 2, 5]oxadiazol-5-amine) | A cell-permeable benzoxadiazolamine that prevents HIF-2alpha-HIF-beta/ARNT heterodimeration by perturbing HIF-2alpha Per-ARNT-Sim/PAS-B domain surface beta-sheet conformation via a 1:1 stoichiometric binding (KD = 81nM), while exhibiting no affinity toward HIF-1alphaPAS-B domain. Shown to be metabolically stable and non-cytotoxic in cultures and selectively inhibit hypoxia-induced HIF-2a DNA binding and HIF-2alpha-dependent EPO mRNA upregulation (1 to10uM for 6-12h), but not HIF-1alpha DNA binding or HIF-1alpha-dependent PGK1 mRNA upregulation, in Hep3B cells. Unlike HIF Inhibitors I-VI, this compound does not affect the cellular protein or mRNA levels of HIF-1alpha & HIF-2alpha. Group: Biochemicals. Grades: Highly Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg. Molecular Formula: C??H?ClFN?O?, Molecular Weight: 308.65. US Biological Life Sciences. | Worldwide |
| N-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine | N-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1422955-31-4. Molecular Formula: C12H6ClFN4O3. Mole Weight: 308.65. Catalog: APB1422955314. |  |
| TC-S 7009 | TC-S 7009 is a high affinity and selective HIF-2α inhibitor (Kd = 81 nM) that displays >60-fold selectivity for HIF-2α over HIF-1&alpha. TC-S 7009 binds to the HIF-2α PAS-B domain to disrupt HIF-2α-ARNT heterodimerization, decrease HIF-2α DNA-binding and suppress expression of HIF-2α target genes in vitro. Synonyms: TCS 7009; TC S 7009; TC-S 7009; N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine. Grades: ≥99% by HPLC. CAS No. 1422955-31-4. Molecular formula: C12H6ClFN4O3. Mole weight: 308.65. | |
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