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Intermediate in the synthesis of HCV polymerase inhibitors. Group: Biochemicals. Alternative Names: 1-(2-Cyclopropylethyl)-6-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione. Grades: Highly Purified. CAS No. 477933-12-3. Pack Sizes: 50mg. US Biological Life Sciences.
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine, a remarkable antiviral compound, demonstrates its efficacy in combatting herpes simplex and varicella-zoster viruses. Through its robust inhibition of viral DNA polymerase, this agent dismantles viral replication processes, thereby alleviating associated symptoms. With its exceptional selectivity towards viral enzymes, this therapeutic option proves to be a commendable approach for managing viral infections among affected individuals. Synonyms: 6-Methylpurine-2'-deoxy-2'-fluoro-beta-D-arabinoriboside. Grades: ≥95%. CAS No. 2095417-72-2. Molecular formula: C11H13FN4O3. Mole weight: 268.24.
1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is an efficacious pharmaceutical compound that has been extensively studied to treat viral infections caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), and cytomegalovirus (CMV). The remarkable feature of this drug is its ability to effectively inhibit viral DNA polymerase, thereby halting viral replication and preventing spread. As nucleoside analogue, it is a preferred choice for combination therapy to achieve superior antiviral potency. The exquisite chemical structure of this compound enables it to bind to the viral polymerase in a unique manner, conferring its remarkable therapeutic benefit. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-(3-Fluoro-4-nitrobenzoyl)-2-imidazolidinone
1-(3-Fluoro-4-nitrobenzoyl)-2-imidazolidinone is derived from 3-Fluoro-4-nitrobenzoic Acid (F595033), which is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1283965-40-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C10H8FN3O4, Molecular Weight: 253.19. US Biological Life Sciences.
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1- β-D-Arabinofuranosyluracil-2-C-methyl
1- β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 114262-49-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C10H14N2O6, Molecular Weight: 258.23. US Biological Life Sciences.
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1- β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
1- β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1- β-D-Arabinofuranosyluracil-2-C-methyl (A764005), an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256490-38-6. Pack Sizes: 2.5mg, 75mg. Molecular Formula: C913CH11D3N2O6, Molecular Weight: 262.24. US Biological Life Sciences.
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1-Bis(4-fluorophenyl)methyl Piperazine
1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. Group: Biochemicals. Grades: Highly Purified. CAS No. 27469-60-9. Pack Sizes: 1g, 10 g. Molecular Formula: C17H18F2N2. US Biological Life Sciences.
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1-Bis(4-fluorophenyl)methyl Piperazine-d8
1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H10D8F2N2. US Biological Life Sciences.
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1H,1H,2H,2H-Perfluorohexanol
1H,1H,2H,2H-Perfluorohexanol is used in the synthesis of polymer coatings with controlled surface topography. As well used in the preparation of star polymers as fluorous nanocapsules for the encapsulation and release of perfluorinated compounds. Group: Biochemicals. Grades: Highly Purified. CAS No. 2043-47-2. Pack Sizes: 5g, 10g. Molecular Formula: C6H5F9O. US Biological Life Sciences.
1-O-Acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside is an intriguing fluorinated nucleoside derivative, firmly established in HCV research as a potent inhibitor of HCV NS5B polymerase that plays an indispensable role in HCV replication. 1-O-Acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside has shown a low cytotoxicity while efficiently targeting HCV NS5B polymerase, thus, demonstrating a remarkable specificity. These combined characteristics project a promising potential for 1-O-acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside in the treatment of HCV infection, indicating its remarkable significance to medical treatment through strict HCV inhibition. CAS No. 122654-34-6.
1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside is a powerful nucleoside analogue with potent antiviral properties used to combat infectious viruses such as influenza and hepatitis B that replicate through polymerase activity. Additionally, this incredible compound has been extensively researched for its cytotoxic potential against multidrug-resistant cancer cells, offering a new frontier for cancer treatment. With its precise targeting and potent activity, 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside is a promising treatment option for a range of viral and cancerous diseases. Synonyms: 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside; SCHEMBL5974836. CAS No. 149623-91-6. Molecular formula: C21H19FO7. Mole weight: 402.4.
2-[1-(4,4-Difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide is a nuclear protein poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor. PARP-1 is involved with the signaling and repair of DNA and a target in oncology. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262417-51-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H24F3N3O2, Molecular Weight: 395.42. US Biological Life Sciences.
2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine, a highly effective antiviral compound, demonstrates remarkable capabilities in combating viral infections. By impeding viral RNA replication and selectively targeting the viral polymerase, it exhibits an extensive range of activity against diverse viruses such as influenza and herpesvirus. Synonyms: 2',3',5'-Tri-O-benzoyl-2'-β-C-methyl-5-fluorouridine. Grades: ≥95%. CAS No. 2072145-49-2. Molecular formula: C31H25FN2O9. Mole weight: 588.54.
2-(4-Bromo-2-fluorophenyl)-2-methylpropanenitrile
2-(4-Bromo-2-fluorophenyl)-2-methylpropanenitrile is used in the discovery of dihydropyrone series as HCV RNA-dependent RNA polymerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 749928-77-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H9BrFN, Molecular Weight: 242.09. US Biological Life Sciences.
2,5-Dibromo-3-octylthiophene. Uses: Conducting polymer precursor. Group: other electronic materials synthetic tools and reagents. Alternative Names: 2,5-DIBROMO-3-OCTYLTHIOPHENE; 4-FLUORO-2-TRIFLUOROMETHYLPHENYL ISOTHIO; 2,5-DibroMo-3-n-octylthiophene; DibroMo-3-octylthioph. CAS No. 149703-84-4. Pack Sizes: Packaging 1, 5 g in glass bottle. Product ID: 2,5-dibromo-3-octylthiophene. Molecular formula: 354.14. Mole weight: C12H18Br2S. CCCCCCCCc1cc(Br)sc1Br. 1S / C12H18Br2S / c1-2-3-4-5-6-7-8-10-9-11 (13) 15-12 (10) 14 / h9H, 2-8H2, 1H3. PJGBSUPPENVFAD-UHFFFAOYSA-N. ≥ 97%.
2,5-Dibromo-3-octylthiophene
Conducting polymer precursor. Group: Organic & printed electronics. Alternative Names: 2,5-DIBROMO-3-OCTYLTHIOPHENE;4-FLUORO-2-TRIFLUOROMETHYLPHENYL ISOTHIO;2,5-DibroMo-3-n-octylthiophene;DibroMo-3-octylthioph. CAS No. 149703-84-4. Molecular formula: C12H18Br2S. Mole weight: 354.14. Purity: ≥ 97%. IUPACName: 2,5-dibromo-3-octylthiophene. Canonical SMILES: CCCCCCCCc1cc(Br)sc1Br. Density: 1.44 g/mL at 25 °C (lit.). Catalog: ACM149703844-2.
2,5-Di-O-benzyl-3-deoxy-3-fluoro-b-D-ribofuranose
2,5-Di-O-benzyl-3-deoxy-3-fluoro-b-D-ribofuranose is a structurally modified synthetic derivative that has gained considerable attention as a prospective antiviral agent. Its potential usage as a therapeutic agent in the treatment of contemporarily prevalent RNA viruses such as HCV and SARS-CoV make it a significant molecule with undeniable biomedical significance. Specifically, this compound has been investigated as a nucleoside analogue for its ability to inhibit viral RNA replication through impeding the virus's RNA-dependent RNA polymerase. CAS No. 123369-31-3. Molecular formula: C19H21FO4. Mole weight: 332.4.
2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-ribofuranosyl)purine is considered a potent antiviral agent within the biomedical industry, this intriguing substance showcases its efficacy in combating specific viral infections like herpes and hepatitis. By skillfully interfacing with viral polymerases, it curtails viral replication, leading to a consequential reduction in the severity and duration of these afflictions. Molecular formula: C10H13FN6O3. Mole weight: 284.25.
2-Amino-4-chloro-5-fluorobenzoic acid is used to synthesize 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization. Group: Biochemicals. Grades: Highly Purified. CAS No. 108288-16-0. Pack Sizes: 100mg, 1g. Molecular Formula: C7H5ClFNO2, Molecular Weight: 189.57. US Biological Life Sciences.
2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside, a robust antiviral agent, exhibits considerable effectiveness in combatting DNA viruses. By suppressing viral replication and diminishing viral load, this nucleoside analogue adeptly obstructs viral DNA polymerase. Remarkably, its exceptional targeting of infected cells while minimizing harm to healthy cells renders it a highly promising candidate for antiviral therapy. Synonyms: 2-Amino-6-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine; (2R,3R,4S,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 6-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-2-amine. Grades: ≥95%. CAS No. 144924-88-9. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine, a powerful antiviral drug, has proven effective in controlling hepatitis C viral infections. Its potent mechanism of action involves binding to and inhibiting the viral RNA polymerase, thereby reducing viral replication, viral load and disease progression. Not content with tackling hepatitis C alone, this remarkable compound has also been investigated for its potential use against HIV, influenza and even select cancers like chronic lymphocytic leukemia. Its versatility and unique mechanism of action make 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine a valuable addition to any clinician's armamentarium in the battle against viral infections and other diseases. Synonyms: 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-β-D-arabino-adenosine; (2R,3R,4S,5R)-5-[2-amino-6-(dimethylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)oxolan-3-ol. Grades: ≥95%. CAS No. 2171103-80-1. Molecular formula: C12H17FN6O3. Mole weight: 312.30.
2-Bromo-9,9-dimethylfluorene
2-Bromo-9,9-dimethylfluorene is a fluorene derivative which shows π-electron conjugation. It has a high fluorescent and high electron delocalization. It can be used as a non-linear optical (NLO) material. It can be synthesized by using 2-bromofluorene and iodomethane as the major reactants. It can be majorly used in organic electronic based applications. Uses: 2-bromo-9,9-dimethylfluorene can be used as a conducting polymer in the fabrication of a variety of devices which include photoelectronic devices, organic light emitting diodes (oleds) and organic solar cells (oscs). this material is a popular synthetic precursor for oled materials to make devices that efficiently emit a deep blue color. Group: Organic & printed electronics. Alternative Names: 9,9-Dimethyl-2-bromofluorenone;2-bromo-9,9-dimethyl-fluororene;2-Bromo-9,9-dimethylfluorene;2-Bromo-9,9-dimethylfluuoren;2-BROMO-9,9-DIMETHYLFLUOROENE;2-Bromo-9,9-dimethyl;9,9-Dimethyl-2-bromofluorene;2-Bromo-9,9-dimethylfluoren. CAS No. 28320-31-2. Molecular formula: C15H13Br. Mole weight: 273.17. Purity: 95%+. IUPACName: 2-bromo-9,9-dimethylfluorene. Canonical SMILES: CC1(C2=CC=CC=C2C3=C1C=C(C=C3)Br)C. Catalog: ACM28320312-3.
2-Bromo-9,9-dimethylfluorene
2-Bromo-9,9-dimethylfluorene is a fluorene derivative which shows π-electron conjugation. It has a high fluorescent and high electron delocalization. It can be used as a non-linear optical (NLO) material. It can be synthesized by using 2-bromofluorene and iodomethane as the major reactants. It can be majorly used in organic electronic based applications. Uses: 2-bromo-9,9-dimethylfluorene can be used as a conducting polymer in the fabrication of a variety of devices which include photoelectronic devices, organic light emitting diodes (oleds) and organic solar cells (oscs). this material is a popular synthetic precursor for oled materials to make devices that efficiently emit a deep blue color. Group: Small molecule semiconductor building blocksorganic light-emitting diode (oled) materials other electronic materials synthetic tools and reagents. Alternative Names: 9,9-Dimethyl-2-bromofluorenone; 2-bromo-9,9-dimethyl-fluororene; 2-Bromo-9,9-dimethylfluorene; 2-Bromo-9,9-dimethylfluuoren; 2-BROMO-9,9-DIMETHYLFLUOROENE; 2-Bromo-9,9-dimethyl; 9,9-Dimethyl-2-bromofluorene; 2-Bromo-9,9-dimethylfluoren. CAS No. 28320-31-2. Pack Sizes: Packaging 1 g in glass bottle. Product ID: 2-bromo-9,9-dimethylfluorene. Molecular formula: 273.17. Mole weight: C15H13Br. CC1(C2=CC=CC=C2C3=C1C=C(C=C3)Br)C. InChI=1S/C15H13Br/c1-15 (2)13-6-4-3-5-11 (13)12-8-7-10 (16)9-14 (12)15/h3-9H, 1-2H3. MBHPOBSZPYEADG-UHFFFAOYSA-N. 95%+.
2-?Chloro-?1-?(3-?fluorobenzyloxy)?-?4-?nitrobenzene is a reagent used in the synthesis of novel indole-2-carboxamide derivative as anti-inflammatory agents used in the treatment of sepsis. Also an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. Group: Biochemicals. Grades: Highly Purified. CAS No. 443882-99-3. Pack Sizes: 5g, 10g. Molecular Formula: C13H9ClFNO3, Molecular Weight: 281.67. US Biological Life Sciences.
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2-Chloro-2'-deoxy-2'-fluoroadenosine
2-Chloro-2'-deoxy-2'-fluoroadenosine, renowned for its exceptional properties, stands as a paramount nucleoside analogue hailed within the biomedicine realm. Exhibiting formidable efficacy as an antiviral warrior, it garners prominence in combatting viral infections. Pertinently, its profound interaction with viral polymerases effectively hampers viral replication, rendering it a beacon of hope in the face of relentless viral diseases. CAS No. 156357-18-5. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt
PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. Synonyms: PSI-7409 (tetrasodium);tetrasodium; [[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate. Grades: ≥98% (HPLC). CAS No. 1621884-22-7. Molecular formula: C10H12FN2Na4O14P3. Mole weight: 588.09.
2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine
2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine is a potent antiviral compound, exerting its effects by selectively impeding the replication of viral RNA through the inhibition of its RNA-dependent RNA polymerase. Synonyms: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine; (2R,3R,4S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2-methoxy-9H-purin-6-amine. Grades: ≥95%. CAS No. 1093278-52-4. Molecular formula: C11H14FN5O4. Mole weight: 299.26.
2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine
2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine is a nucleoside analog used as an antiviral drug against hepatitis B virus (HBV) and hepatitis C virus (HCV). It inhibits viral polymerase activity and causes chain termination during viral genome replication, thus reducing viral load in infected individuals. This product has potential as a therapeutic agent against other RNA viruses such as Ebola and Zika. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinoribofuanosyl)-2(1H)-pyrimidinone; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-Arafluorozebularine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)pyrimidin-2-(1H)-one. Grades: ≥95%. CAS No. 136675-88-2. Molecular formula: C9H11FN2O4. Mole weight: 230.19.
2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine
2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine is an exceptional antiviral compound, exhibiting remarkable potential in the research of biomedicine for tackling viral afflictions. Its robustness lies in its ability to suppress viral replication through the selective inhibition of viral polymerase activity, impeding viral RNA synthesis. Uses: Enzyme inhibitors. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; FF-Ara-ura; 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-fluorouracil. Grades: ≥95%. CAS No. 69123-95-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18.
2'-Deoxy-2'-fluoro-5-methylcytidine
2'-Deoxy-2'-fluoro-5-methylcytidine is a potent antiviral compound used in the reserch of various viral diseases. It exhibiting significant activity against influenza A and B viruses, including oseltamivir-resistant strains. This nucleoside analogue interferes with viral replication by inhibiting RNA synthesis and polymerase activity. Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-5-methyl-; 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 182495-80-3. Molecular formula: C10H14FN3O4. Mole weight: 259.23.
2-Deoxy-2-fluoro-6-S-methyl-6-thio-arabino-inosine, a potent nucleoside analog, serves as an effective antiviral medication for treating hepatitis B and C among other viral infections. By suppressing viral polymerase activity, this drug effectively hinders viral replication and dispersal, thereby counteracting the progression of the targeted ailment. Synonyms: 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methylthiopurine; (2R,3R,4S,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methylsulfanyl-purin-9-yl)-tetrahydro-furan-3-ol; (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)-6-(methylsulfanyl)-9H-purine. Grades: ≥95%. CAS No. 109304-12-3. Molecular formula: C11H13FN4O3S. Mole weight: 300.31.
2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt
2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an indispensable compound in the field of biomedicine, finding extensive application in the research and development of antiviral agents to combat problematic viral infections such as HIV and hepatitis C. Offering exceptional efficacy, this product acts as a highly proficient substrate for DNA polymerases, thereby impeding viral replication through the disruption of nucleotide integration into the viral DNA structure. Grades: 95%. Molecular formula: C9H11FN3O13P3·Li4. Mole weight: 508.88.
2'-Deoxy-2'-fluoroguanosine
It is an influenza viral polymerase inhibitor like Ribavirin, used as an antiviral drug against avian (H5N1) influenza virus. Uses: Antiviral agents. Synonyms: 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine; 2'-Fluoro-2'-deoxyguanosine; 2-Amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 2'-deoxy-2'-fluoro-; 2'-Fluoro-Riboguanosine. Grades: ≥95%. CAS No. 78842-13-4. Molecular formula: C10H12FN5O4. Mole weight: 285.23.
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt, an indispensable constituent in biomedicine, plays a vital and intricate role in the synthesis of nucleic acids. As an essential nucleotide analog, this compound facilitates the in-depth investigation of intricate DNA sequencing, replication, and transcription phenomena. Moreover, its integration in the development of antiviral pharmaceuticals specifically targeting viral DNA polymerases and reverse transcriptases contributes substantially to the realm of therapeutic interventions against a vast array of viral infections. Grades: 95%. Molecular formula: C10H11FN5O13P3Li4. Mole weight: 548.90.
2-Deoxy-2-fluoroisoguanosine
2-Deoxy-2-fluoroisoguanosine is a formidable antiviral compound, exhibiting its efficacy in research of combating viral infections instigated by DNA viruses, such as herpesviruses. By impeding viral replication via selective inhibition of viral DNA polymerase, this compound effectively diminishes viral load. It is renowned for its nucleoside analog properties. Grades: ≥ 98%.
2'-Deoxy-2'-fluoro-L-uridine
2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication. Group: Inhibitors. Alternative Names: (S)-2-chloro-butyric acid dimethylamide; L-2-Chlor-N,N-dimethyl-butyramid; L-2-deoxy-2-fluorouridine; (S)-2-Chlor-buttersaeure-dimethylamid; 2-Chloro-N,N-dimethylbutyramide; Butanamide,2-chloro-N,N-dimethyl; 2-fluoro-L-uridine. CAS No. 622785-69-7. Molecular formula: C9H11FN2O5. Mole weight: 246.2. Appearance: White to off-white solid. Purity: 0.96. IUPACName: 1-[(2R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Canonical SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F. Catalog: ACM622785697.
2'-Deoxy-2'-fluoro-N1-methyluridine
2'-Deoxy-2'-fluoro-N1-methyluridine, a potent compound in biomedicine, assumes a pivotal role in curbing viral infections of RNA origin. This nucleoside analog acts as a formidable antagonist against viral replication, directing its efforts principally towards the viral polymerase enzyme. It has been shown to be effective against a wide range of RNA viruses, including influenza, hepatitis C, and respiratory syncytial virus (RSV). Synonyms: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4-dione. Grades: ≥95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
2'-Deoxy-2'-fluoro-N3-[(pyridin-2-yl)methyl]-beta-D-arabinouridine, a highly sophisticated antiviral agent , exhibits immense proficiency in combating specific viral infections. Employing a meticulous approach, it precisely intervenes with the replication mechanism of the virus, effectively obstructing the viral polymerase enzyme and impeding the synthesis of viral RNA. Remarkably, this pharmaceutical marvel has been proven efficacious in battling diverse viral ailments including hepatitis C and respiratory syncytial virus (RSV) infections. Synonyms: 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]-β-D-arabinouridine. Grades: ≥95%. CAS No. 2072145-51-6. Molecular formula: C15H16FN3O5. Mole weight: 337.30.
2'-Deoxy-2'-fluoro-N3-[(pyridin-4-yl)methyl]-beta-D-arabinouridine is a highly effective antiviral compound widely used in the biomedical field as a powerful therapeutic intervention against RNA viruses. By selectively modulating viral RNA polymerase, it rapidly inhibits viral replication and effectively prevents viral proliferation and transmission. Synonyms: 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]-β-D-arabinouridine. Grades: ≥95%. CAS No. 2072145-47-0. Molecular formula: C15H16FN3O5. Mole weight: 337.30.
2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt
2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt is a vital component in the biomedicine field. It is commonly used in molecular biology research and drug development. This compound serves as a substrate for reverse transcriptases and DNA polymerases, playing a crucial role in the synthesis of various modified nucleic acids. It is particularly utilized in the study of RNA function and structure and the development of antiviral drugs targeting RNA viruses. Synonyms: 2'F-dUTP.Na. Grades: 95%. Molecular formula: C9H14FN2O14P3·Na. Mole weight: 509.12 (free acid).
2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine
2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine, an intriguing nucleoside analog, has undergone scrutiny for its antiviral activity against hepatitis C virus. Excitingly, not only has it shown potential as an antiviral therapy, but it has also been efficacious against certain variants of cancer, such as colon cancer and leukemia. How does it manage to be such a promising candidate? By inhibiting the viral NS5B polymerase, this compound disrupts viral RNA replication. Such a revolutionary advancement may prove crucial in future antiviral therapies. Molecular formula: C30H29FN2O7. Mole weight: 548.57.
2-?Ethylhexyl 4, ?6-?Dibromo-?3-?fluorothieno[3, ?4-?b]?thiophene-?2-?carboxylate can be used in technical or engineered material use of design and synthesis of polymers based on alkylthiophenyl side chains and variant acceptor moieties for polymer solar cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1237479-38-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H17Br2FO2S2, Molecular Weight: 472.23. US Biological Life Sciences.
2-Fluoro-1,4-dimethoxybenzene is used as a reagent to synthesize fluoro analogues of Phenstatin, a tubulin polymerization inhibitor that has potential use as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 82830-49-7. Pack Sizes: 2.5g, 10g. Molecular Formula: C8H9FO2, Molecular Weight: 156.15. US Biological Life Sciences.
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2'-Fluoro-2'-deoxy-arabinofuranosyl-cytosine
2-Fluoro-2-deoxy-arabinofuranosyl-cytosine is an efficacious and safe antiviral compound, having applications in research of combating diverse viral infections such as hepatitis B and C. Its mode of action relies on targeting the viral polymerase enzyme, thereby impeding the research and development of viral DNA and hindering replication. Synonyms: 2'-FANA-C; 1-(2'-Fluoro-2'-deoxy-β-D-arabinofuranosyl)cytosine hydrochloride. Grades: ≥ 97%. Molecular formula: C9H12FN3O4 (free base). Mole weight: 245.21 (free base).
2'-Fluoro-2'-deoxy-arabinofuranosyl-uracil
2'-Fluoro-2'-deoxy-arabinofuranosyl-uracil is an exceptional antiviral compound utilized in the field of compound, exhibiting remarkable efficacy in research of combating diversified viral infections. Its unique mechanism of action involves the selective inhibition of viral polymerases, thereby impeding the replication of viral DNA/RNA. Synonyms: 2'-FANA-U; 1-(2'-Fluoro-2'-deoxy-β-D-arabinofuranosyl)uracil. Grades: ≥ 97%. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
2'-Fluoro-2'-deoxycytidine-5'-triphosphate trisodium salt
2'-Fluoro-2'-deoxycytidine-5'-triphosphate trisodium salt is an essential molecule in the realm of molecular biology. With its ability to serve as a substrate for DNA polymerase and incorporating into DNA during PCR amplification, it plays a crucial role in gene expression. The fluorine nullifies the destabilizing effects on the PCR products, thereby improving its specificity, making it a preferred choice for mutation analysis and diagnostic testing. Furthermore, its potentiality as an antiviral agent adds to its importance as a contender for the treatment of chronic hepatitis B. Synonyms: 2'-Fluoro-dCTP trisodium salt; 2'-Deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate) trisodium salt. Grades: ≥97% by HPLC. Molecular formula: C9H12FN3Na3O13P3. Mole weight: 551.09.
2'-Fluoro-2'-deoxyguanosine-5'-triphosphate trisodium salt
2'-Fluoro-2'-deoxyguanosine-5'-triphosphate trisodium salt, a potent nucleotide analogue, displays antiviral activity by inhibiting viral DNA polymerase. Employed in the treatment of Hepatitis B and Herpes, it is noted for its ability to enhance the pharmacological features of nucleotide-based antiviral medications through its structural modifications. The utilization of this molecule is paramount in the development of novel antiviral therapies. Synonyms: 2'-Fluoro-dGTP trisodium salt; 2'-Deoxy-2'-fluoroguanosine 5'-(tetrahydrogen triphosphate) trisodium salt. Grades: ≥97% by HPLC. Molecular formula: C10H12FN5Na3O13P3. Mole weight: 591.12.
2'-Fluoro-2'-deoxy-N6-methylarabinoadenosine
2'-Fluoro-2'-deoxy-N6-methylarabinoadenosine is an intriguing nucleoside analog extensively employed in the realm of compound due to its exceptional antiviral attributes. With a unique mechanism of action, it selectively obstructs viral RNA research and development by meticulously honing in on viral polymerases. Synonyms: N6-methyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine; (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-N-methyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 126502-12-3. Molecular formula: C11H14FN5O3. Mole weight: 283.26.
2'-Fluoro-2'-deoxyuridine-5'-triphosphate trisodium salt
2'-Fluoro-2'-deoxyuridine-5'-triphosphate trisodium salt, a nucleotide analog in biochemistry and molecular biology, stands out due to its versatility as a substrate for DNA Polymerases in DNA synthesis studies. Moreover, it shows promise as an anti-cancer agent in treating breast cancer and pancreatic cancer by hindering DNA replication. With this in mind, its relevance and significance linger in the scientific community and beyond. Synonyms: 2'-Deoxy-2'-fluorouridine 5'-(tetrahydrogen triphosphate) trisodium salt; 2'-Fluoro-dUTP trisodium salt. Grades: ≥97% by HPLC. Molecular formula: C9H11FN2Na3O14P3. Mole weight: 552.08.
2-Fluoro, 2'-Fluoro-dATP
2-Fluoro, 2'-Fluoro-dATP, a nucleotide analog, is a complex chemical compound that has been widely employed in numerous research studies in order to elucidate the functions of DNA synthesis in the pathogenesis of cancer and various other diseases. Not only can this enigmatic molecule potently inhibit DNA polymerases, but it can also impede DNA replication, ultimately paving the way for the development of novel therapies targeting cancer and its related afflictions. Synonyms: (2F,2'F-dATP); 2,2'-Difluoro-2'-deoxyadenosine-5'-triphosphate, Tetralithium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14F2N5O12P3 (free acid). Mole weight: 527.16 (free acid).
2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoic Acid is an intermediate used in the synthesis of phthalazinone scaffolds that are potent inhibitors of poly(ADP-ribose) polymerase, and also in the design of isocorydine derivatives with anticancer effect. Group: Biochemicals. Grades: Highly Purified. CAS No. 763114-26-7. Pack Sizes: 250mg, 500mg. Molecular Formula: C16H11FN2O3, Molecular Weight: 298.27. US Biological Life Sciences.
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile is an intermediate used in the synthesis of phthalazinone scaffolds that are potent inhibitors of poly(ADP-ribose) polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1021298-68-9. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H10FN3O, Molecular Weight: 279.27. US Biological Life Sciences.
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2'-Fluoro-ara-dATP
2'-Fluoro-ara-dATP is a pivotal constituent employed in cutting-edge biomedical studies, offering insights into the intricate involvement of nucleotides and their derivatives within DNA research and development and repair processes. As a DNA polymerase substrate during sequencing and amplification methodologies, it assuming a critical role. Synonyms: (2'F-ara-dATP); 2'-Fluoro-2'-deoxy-ara-adenosine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-adenine-5'-triphosphate; 2'-F-ara-2'-dATP. Grades: ≥ 95% by HPLC. Molecular formula: C10H15FN5O12P3 (free acid). Mole weight: 509.17 (free acid).
2'-Fluoro-ara-dCTP
2'-Fluoro-ara-dCTP, a nucleoside analogue of utmost importance in biomedical research and diagnostics, is extensively employed in multifarious analysis encompassing DNA polymerase studies and polymerase chain reaction assays. Its clinical usage in the treatment of hematological malignancies and solid tumors underscores its prodigious value in the medical fraternity. Synonyms: (2'F-ara-dCTP); 2'-Fluoro-2'-deoxy-ara-cytidine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytosine-5'-triphosphate; 2'-F-ara-2'-dCTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H15FN3O13P3 (free acid). Mole weight: 485.15 (free acid).
2'-Fluoro-ara-dGTP
2-Fluoro-ara-dGTP - an analogue of nucleoside - has been effectively utilized as a substrate for DNA polymerases in examining DNA replication and repair, and demonstrates potential in targeting specific cancer types, such as lymphoma and leukemia. Its capacity to cause strand termination when integrated into DNA during replication is a promising trait for the treatment of these diseases through chemotherapy. Synonyms: (2'F-ara-dGTP); 2'-Fluoro-2'-deoxy-ara-guanosine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-guanine-5'-triphosphate; 2'-F-ara-2'-dGTP. Grades: ≥ 95% by HPLC. Molecular formula: C10H15FN5O13P3 (free acid). Mole weight: 525.17 (free acid).
2'-Fluoro-ara-dUTP
2'-Fluoro-ara-dUTP, a nucleotide analogue, is utilized as a substrate for DNA polymerases in molecular biology applications, its incorporation into DNA during replication results in chain termination and inhibition of DNA synthesis. Its antiviral and anticancer properties have been widely researched, attributed to its ability to inhibit the replication of viral DNA and RNA, as well as inducing apoptosis in cancer cells, making it a vital tool in the battle against these diseases. Synonyms: (2'F-ara-dUTP); 2'-Fluoro-2'-deoxy-ara-uridine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-uracil-5'-triphosphate; 2'-F-ara-2'-dUTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H14FN2O14P3 (free acid). Mole weight: 486.13 (free acid).
2-Fluorostyrene
contains 4-tert-butylcatechol as inhibitor. Uses: Used for fluorinated hyperbranched polymers. Group: Monomers. Alternative Names: 1-ethenyl-2-fluorobenzene; 1-Fluoro-2-vinylbenzene; 2-FLUOROSTYRENE; O-FLUOROSTYRENE; 2-Fluorostyrene,98%; 2-Fluorostyrene 99%; 2-Fluorostyrene99%; 2-FLUOROSTYRENE , STABILIZED WITH 0.1% 4-TERT-BUTYLCATECHOL. CAS No. 394-46-7. Pack Sizes: 5g. Product ID: 1-ethenyl-2-fluorobenzene. Molecular formula: 122.14. Mole weight: H2C=CHC6H4F. Fc1ccccc1C=C. 1S/C8H7F/c1-2-7-5-3-4-6-8(7)9/h2-6H, 1H2. YNQXOOPPJWSXMW-UHFFFAOYSA-N. 0.98.
2-Fluorostyrene
contains 4-tert-butylcatechol as inhibitor. Uses: Used for fluorinated hyperbranched polymers. Group: Polymer/macromoleculestyrene monomers. Alternative Names: 1-Fluoro-2-vinylbenzene. CAS No. 394-46-7. Molecular formula: C8H7F. Mole weight: 122.14 g/mol. Appearance: Colorless Liquid. Purity: 0.95. IUPACName: 1-ethenyl-2-fluorobenzene. Canonical SMILES: Fc1ccccc1C=C. Density: 1.025 g/mL at 25 °C (lit.). ECNumber: 206-896-1. Catalog: ACM-MO-394467.
(2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine
PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Synonyms: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 863329-66-2. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 874638-80-9. Pack Sizes: 1g, 5g. Molecular Formula: C20H17FO6, Molecular Weight: 372.34. US Biological Life Sciences.
(2'R) -2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1393526-40-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H41FN2O5Si2. US Biological Life Sciences.
(2'R) -2'-Deoxy-3'-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1244762-86-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H27FN2O5Si. US Biological Life Sciences.
((2R,3R,4R,5R)-3-(Benzoyloxy)-4-fluoro-5-(4-methoxy-2-oxopyrimidin-1(2H)-yl)-4-methyltetrahydrofuran-2-yl)methyl Benzoate is an intermediate in synthesizing PSI 6130 (P839680), which is an experimental treatment for hepatitis C. PSI 6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI 6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C25H23FN2O7. US Biological Life Sciences.
((2R,3R,4R,5R)-3-(Benzoyloxy)-4-fluoro-5-(4-methoxy-2-oxopyrimidin-1(2H)-yl)-4-methyltetrahydrofuran-2-yl)methyl Benzoate is an intermediate in synthesizing PSI 6130, which is an experimental treatment for hepatitis C. PSI 6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI 6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Molecular formula: C25H23FN2O7. Mole weight: 482.46.
(2R,3R,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate is an intermediate in synthesizing PSI 6130 (P839680), which is an experimental treatment for hepatitis C. PSI 6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI 6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H22FN3O6. US Biological Life Sciences.
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