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United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)impurity standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: Fluorouracil, 5-Fluoropyrimidine-2,4(1H,3H)-dione, Flucytosine Imp. A (EP).
Fluorouracil
United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; api standards; british pharmacopoeia; european pharmacopoeia (ph. eur.); impurity standards; pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: Fluorouracil, 5-Fluoropyrimidine-2,4(1H,3H)-dione, Flucytosine Imp. A (EP). CAS No. 51-21-8. Pack Sizes: 250MG. IUPAC Name: 5-fluoro-1H-pyrimidine-2,4-dione. Molecular formula: C4H3FN2O2. Mole weight: 130.08. Catalog: APS51218. SMILES: FC1=CNC(=O)NC1=O. Format: Neat.
Fluorouracil Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fluorouracil Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fluorouracil Related Compound E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fluorouracil Related Compound F
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
1-[(2'-ACETOXYETHOXY)METHYL]-5-FLUOROURACIL
1-[(2'-ACETOXYETHOXY)METHYL]-5-FLUOROURACIL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[(2'-ACETOXYETHOXY)METHYL]-5-FLUOROURACIL. Product Category: Heterocyclic Organic Compound. CAS No. 77474-49-8. Molecular formula: C9H11FN2O5. Mole weight: 246.19. Product ID: ACM77474498. Alfa Chemistry ISO 9001:2015 Certified.
1-(2-Deoxy-5-O-MMT-b-D-threo-pentofuranosyl)-5-fluorouracil, commonly known as 5-FU, holds paramount significance in the realm of biomedicine. This intricate compound has garnered substantial attention due to its immense potential as an antineoplastic agent, with a specific focus on combatting colorectal, breast, and head and neck cancers. Through its ability to impede DNA synthesis and stimulate apoptotic processes in malignant cells, this compound showcases remarkable cytotoxic effects. Its extraordinary structure and mechanism render it an invaluable asset in the pursuit of cancer therapy research. Synonyms: 5-Fluoro-1- ( (2R, 4R, 5R) -4-hydroxy-5- ( ( (4-methoxyphenyl) diphenylmethoxy) methyl) tetrahydrofuran-2-yl) pyrimidine-2, 4 (1H, 3H) -dione. CAS No. 121353-92-2. Molecular formula: C29H27FN2O6. Mole weight: 518.53.
1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil, an effective antineoplastic agent employed in the management of diverse malignancies such as colorectal, breast, and pancreatic cancer, showcases its mechanistic action by suppressing the vital enzyme, thymidylate synthase, thereby impeding DNA synthesis. Undoubtedly, this compound's profound pharmacological features render it an indispensable asset within the biomedicine realm, proficiently combating a myriad of malignant conditions. Synonyms: 5-Fluoro-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. CAS No. 955-24-8. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
1,3-Bis(4-methoxybenzyl)-5-fluorouracil
An Intermediate for the synthesis of uracil derivatives. Group: Biochemicals. Alternative Names: 5-Fluoro-1,3-bis[(4-methoxyphenyl)methyl]-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 897304-05-1. Pack Sizes: 100mg. US Biological Life Sciences.
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1,3-Dibenzyl-5-fluorouracil
1,3-Dibenzyl-5-fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluoro-1,3-bis(phenylmethyl)-2,4(1H,3H)-pyrimidinedione, NSC408345. Grades: Highly Purified. CAS No. 75500-02-6. Pack Sizes: 2.5g. US Biological Life Sciences.
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1,3-Di(benzyloxymethyl)-5-fluorouracil
1,3-Di(benzyloxymethyl)-5-fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluoro-1, 3-bis[ (phenylmethoxy)methyl]-2, 4 (1H, 3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 75500-03-7. Pack Sizes: 1g. US Biological Life Sciences.
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1-(b-D-Xylofuranosyl)-5-fluorouracil
1-(b-D-Xylofuranosyl)-5-fluorouracil, also known as Xeloda, is an influential antineoplastic agent used to combat a diverse array of solid tumors and gastrointestinal cancers. Its mechanism of action is to thwart the synthesis of nucleic acids which in turn, allows for the complete nullification of cancer cell development. Synonyms: 1-(beta-D-Xylofuranosyl)-5-fluorouracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-(β-D-xylofuranosyl)-uracil; 5-Fluoro-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
2-Ethoxy-5-fluorouracil
2-Ethoxy-5-fluorouracil. Group: Biochemicals. Grades: Highly Purified. CAS No. 56177-80-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H7FN2O2. US Biological Life Sciences.
Worldwide
5-Fluorouracil
25g Pack Size. Group: Biochemicals, Fluorinated Products. Formula: C4H3FN2O2. CAS No. 51-21-8. Prepack ID 22050130-25g. Molecular Weight 130.08. See USA prepack pricing.
5-Fluorouracil
5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer [1] [2]. 5-Fluorouracil also inhibits HIV [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5-FU. CAS No. 51-21-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 200 mg; 1 g; 5 g. Product ID: HY-90006.
5-Fluorouracil
5-Fluorouracil. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-21-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C4H3FN2O2. US Biological Life Sciences.
Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS). Synonyms: 5-FU; Fluorouracil; Adrucil. Grades: >98%. CAS No. 51-21-8. Molecular formula: C4H3FN2O2. Mole weight: 130.08.
5-Fluorouracil-13C,15N2
5-Fluorouracil- 13 C, 15 N 2 is the 13 C and 15 N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 5-FU- 13 C, 15 N2. CAS No. 1189423-58-2. Pack Sizes: 1 mg. Product ID: HY-90006S1.
5-Fluorouracil-13C,15N2
Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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5-Fluorouracil-15n2
5-Fluorouracil-15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 68941-95-7. Molecular formula: C4H3FN2O2. Mole weight: 132.1. Purity: 98 atom % 15N. Canonical SMILES: O=C1C(F)=C[15NH]C([15NH]1)=O. Product ID: ACM68941957. Alfa Chemistry ISO 9001:2015 Certified.
5-Fluorouracil-6-d1
Labeled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Alternative Names: 5-Fluoro-. Grades: Highly Purified. CAS No. 90344-84-6. Pack Sizes: 5mg. US Biological Life Sciences.
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5-Fluorouracil 99+% (HPLC) USP
5-Fluorouracil 99+% (HPLC) USP. Group: Biochemicals. Grades: USP. CAS No. 51-21-8. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
5-Fluorouracil (FU)
A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Alternative Names: FU. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
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5-Fluorouracil N-b-D-glucuronide
5-Fluorouracil N-b-D-glucuronide is a noteworthy pharmaceutical compound, acting as an illustrious glucuronidated derivative intricately intertwined with 5-Fluorouracil. It can be used in research of malignancies encompassing breast, colon and dermal cancer. Synonyms: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-b-D-glucopyranuronic acid 5-Fluoro-1-(b-D-glucuronopyranosyl)uracil. CAS No. 66048-45-1. Molecular formula: C10H11FN2O8. Mole weight: 306.20.
5-Fluorouracil N- β-D-Glucuronide
5-Fluorouracil N- β-D-Glucuronide is the N-glucuronide derivative of 5-Fluorouracil. 5-Fluorouracil N- β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Group: Biochemicals. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)- β-D-glucopyranuronic Acid; 5-Fluoro-1-( β -D-glucuronopyranosyl) uracil. Grades: Highly Purified. CAS No. 66048-45-1. Pack Sizes: 10mg. US Biological Life Sciences.
Protected 5-Fluorouracil N- β-D-Glucuronide (F596010), a derivative of 5-Fluorouracil. 5-Fluorouracil N- β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Group: Biochemicals. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)- β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. Grades: Highly Purified. CAS No. 77476-81-4. Pack Sizes: 50mg. US Biological Life Sciences.
Protected 5-Fluorouracil N-β-D-Glucuronide, a derivative of 5-Fluorouracil. 5-Fluorouracil N-β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Synonyms: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. CAS No. 77476-81-4. Molecular formula: C17H19FN2O11. Mole weight: 446.34.
5-Fluorouracil (Standard)
5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer [1] [2]. 5-Fluorouracil also inhibits HIV [3]. Uses: Scientific research. Group: Natural products. CAS No. 51-21-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-90006R.
o,o'-Bis(trimethylsilyl)-5-fluorouracil
o,o'-Bis(trimethylsilyl)-5-fluorouracil. Uses: Designed for use in research and industrial production. Additional or Alternative Names: O,O'-BIS(TRIMETHYLSILYL)-5-FLUOROURACIL;BIS(TRIMETHYLSILYL)-5-FLUOROURACIL;2,4-BIS(TRIMETHYLSILYL)-5-FLUOROURACIL. Product Category: Heterocyclic Organic Compound. CAS No. 58138-78-6. Molecular formula: C10H19FN2O2Si2. Mole weight: 274.44. Product ID: ACM58138786. Alfa Chemistry ISO 9001:2015 Certified. Categories: 17242-85-2.
2-Amino-6-fluoro-4-hydrazinopyrimidine
2-Amino-6-fluoro-4-hydrazinopyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-6-FLUORO-4-HYDRAZINOPYRIMIDINE;2-AMINO-4-HYDRAZINO-6-FLUOROURACIL;4(1H)-Pyrimidinone, 2-amino-6-fluoro-, hydrazone (9CI);2-AMINO-6-FLUORO-4-HYDRAZINOPYRIMIDINE,98%;2-Amino-6-hydrazino-4-fluoropyrimidine. Product Category: Heterocyclic Organic Compound. CAS No. 188987-85-1. Molecular formula: C4H6FN5. Mole weight: 143.12. Purity: 0.98. Product ID: ACM188987851. Alfa Chemistry ISO 9001:2015 Certified.
2-Bromo-1,3-difluoropropane
2-Bromo-1,3-difluoropropane is used in the preparation of 5-fluorouracil compounds as dUTPase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 2195-5-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C3H5BrF2, Molecular Weight: 158.97. US Biological Life Sciences.
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2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine
2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine is an exceptional antiviral compound, exhibiting remarkable potential in the research of biomedicine for tackling viral afflictions. Its robustness lies in its ability to suppress viral replication through the selective inhibition of viral polymerase activity, impeding viral RNA synthesis. Uses: Enzyme inhibitors. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; FF-Ara-ura; 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-fluorouracil. Grades: ≥95%. CAS No. 69123-95-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18.
2'-?Deoxy-?5-?[ (trimethylsilyl) ?ethynyl]?uridine 3,5-Dibenzoate is an protected intermediate in the synthesis of 5-Ethyl-2-deoxyuridine (E915020), a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Grades: Highly Purified. CAS No. 140424-82-4. Pack Sizes: 1g. US Biological Life Sciences.
Protected mixture of labeled Floxuridine anomers. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α, β-D-ribofuranosyl-5-fluorouracil-13C,15N2; 3,5-Di-O-p-chlorobenzoyl α, β-5-Fluoro-2'-deoxyuridine-13C,15N2; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α, β-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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3,5-Di-O-p-chlorobenzoyl α-Floxuridine
Protected α-anomer of Floxuridine. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 110558-30-0. Pack Sizes: 10mg. US Biological Life Sciences.
Protected α-anomer of labeled Floxuridine. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil-13C,15N2; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine-13C,15N2; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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3'-Amino-3'-deoxy-5-fluorouridine
3'-Amino-3'-deoxy-5-fluorouridine, an indispensable compound in the biomedical sector, showcases immense potential as an antiviral and anticancer therapeutic agent. Synonyms: 1-((2R,3R,4S,5S)-4-Amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 1-(3-amino-3-deoxy-β-D-ribofuranosyl)-5-fluorouracil. Grades: ≥95%. CAS No. 80955-97-1. Molecular formula: C9H12FN3O5. Mole weight: 261.21.
3'-Deoxy-5-fluorouridine
3'-Deoxy-5-fluorouridine, a robust antineoplastic agent, holds significant promise in combating multiple cancer forms. It orchestrates its therapeutic prowess by intricately obstructing DNA synthesis, thereby impeding malignant tumor proliferation. Synonyms: Uridine, 3'-deoxy-5-fluoro-; 5-Fluoro-3'-deoxyuridine; 1-(3-Deoxy-β-D-erythro-pentofuranosyl)-5-fluorouracil; 5-Fluoro-1-(3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione; 5-Fluoro-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 18829-83-9. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
4-DAMP
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958.
5'-(3-MAL-PEG2-aminobutanoate)-floxuridine
A derivative of Floxuridine. Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection. Synonyms: 5'-(3-MAL-PEG2-aminobutanoate)-floxuridine. Grades: > 95%. Molecular formula: C29H42FN5O13. Mole weight: 687.68.
5-Chlorouracil
Fluorouracil Impurity E has the potential to treat neoplastic and viral diseases. Uses: Used for the experimental and clinical treatment of neoplastic and viral diseases. fluorouracil ep impurity e. Synonyms: 5-chloro-1H-pyrimidine-2,4-dione. Grades: > 95 %. CAS No. 1820-81-1. Molecular formula: C4H3ClN2O2. Mole weight: 146.53.
5-Ethyl-2-deoxyuridine
5-Ethyl-2-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-ethyluridine; 5-Ethyl-1-(2'-deoxy- β-D-ribofuranosyl)uracil; 5-Ethyl-2'-deoxyuridine; 5-Ethyldeoxyuridine; Aedurid; EDU; EUDR; Edoxudine; Epoxudine; ORF 15817; RWJ 15817; β-5-Ethyl-2'-deoxyuridine; β-5-Ethyldeoxyuridine. Grades: Highly Purified. CAS No. 15176-29-1. Pack Sizes: 250mg. US Biological Life Sciences.
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5-Ethyl-2'-deoxyuridine-d5
Isotope labelled 5-Ethyl-2'-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use. Synonyms: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Molecular formula: C11H11D5N2O5. Mole weight: 261.29.
5-Ethyl-2-deoxyuridine-d5
Isotope labelled 5-Ethyl-2-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy- β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-Fluoro-1-(b-L-ribofuranosyl)-uracil
5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a powerful antineoplastic compound, exhibiting immense potential in research of diverse malignancies. Renowned for its impact on inhibiting DNA enhancement and impeding cell proliferation, this remarkable compound emerges as an invaluable asset in the research and development of oncology. Synonyms: 1-beta-L-Ribofuranosyl-5-fluorouracil; L-5-Fluorouridine; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione; 5-Fluoro-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; L-β-Ribofuranosyl-5'-fluorouracil. Grades: 95%. CAS No. 77210-26-5. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluoro-2'-deoxyuridine, 99+%
5-Fluoro-2'-deoxyuridine, 99+%. Group: Biochemicals. Alternative Names: 5-Fluoro-2'-deoxy-D-uridine; Floxuridine; 2'-Deoxy-5-fluorouridine; 1-(2-Deoxy--D-ribofuranosyl)-5-fluorouracil; NSC-27640; FUDR. Grades: Reagent Grade. CAS No. 50-91-9. Pack Sizes: 250mg, 1g, 5g, 25g. Molecular Formula: C9H11FN2O5, Molecular Weight: 246.19. US Biological Life Sciences.
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5-Fluoro-2-ethoxy-4(1H)pyrimidinone
Fluorouracil Impurity F is a derivative of 5-fluorouracil. Uses: Ethoxy-5-fluoro-4(3h)-pyrimidinone (fluorouracil ep impurity f) is a derivative of 5-fluorouracil (3c,15n2 labelled, f596002) which is a potent antineoplastic agent in clinical use. Synonyms: 2-ethoxy-5-fluoro-1H-pyrimidin-6-one. Grades: > 95 %. CAS No. 56177-80-1. Molecular formula: C6H7FN2O2. Mole weight: 158.13.
5-Fluoro-6-hydroxyhydro Uracil (Mixture of Diastereomers)
An impurity of 5-Fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluorodihydro-6-hydroxy-2,4(1H,3H)-pyrimidinedione; NSC 528189. Grades: Highly Purified. CAS No. 37103-91-6. Pack Sizes: 50mg. US Biological Life Sciences.
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5-Fluorodi hydropyrimidine-2, 4-dione
5-Fluorodi hydropyrimidine-2, 4-dione. Group: Biochemicals. Alternative Names: 5,6-Dihydro-5-fluorouracil; 5-Fluoro-5,6-dihydrouracil; 5-Fluorodihydrouracil. Grades: Highly Purified. CAS No. 696-06-0. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C4H5FN2O2. US Biological Life Sciences.
Worldwide
5-Fluorodi hydropyrimidine-2, 4-dione-13C, 15N2
A labeled metabolite of 5-Fluorouracil. Group: Biochemicals. Alternative Names: 5,6-Dihydro-5-fluorouracil-13C,15N2; 5-Fluoro-5,6-dihydrouracil-13C,15N2; 5-Fluorodihydrouracil-13C,15N2; 5-Fluorohydrouracil-13C,15N2; 5-DHFU-13C,15N2. Grades: Highly Purified. CAS No. 1189492-99-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
5-Fluoroorotic Acid Monohydrate (FOA, 5-FOA)
Useful in the identification and selection of the strains of Saccharomyces cerevisiae that contain the mutant ura3- gene. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5-phosphate decarboxylase and are therefore unable to grow on 5-FOA-containing media. Group: Biochemicals. Alternative Names: FOA; 5-FOA; 5-Fluoroorotate; 5-FLUORO-4-PYRIMIDINECARBOXYLIC ACID; 5-FLUORO-1,2,3,6-TETRAHYDRO-2,6-DIOXO-(9CI); 1,2,3,6-TETRAHYDRO-2,6-DIOXO-5-FLUORO-4- PYRIMIDINECARBOXYLIC ACID; 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid. Grades: Molecular Biology Grade. CAS No. 207291-81-4,220141-70-8,703-95-7. Pack Sizes: 500mg, 1g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
5-Fluorouridine
5-Fluorouridine, a metabolite of 5-fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 316-46-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-107856.
5-Fluorouridine
5-Fluorouridine. Group: Biochemicals. Alternative Names: 1-(b-D-Ribofuranosyl)-5-fluorouracil. Grades: Highly Purified. CAS No. 316-46-1. Pack Sizes: 1g, 2g, 5g, 10g. Molecular Formula: C9H11FN2O6. US Biological Life Sciences.
Worldwide
5-Fluorouridine-5'-monophosphate sodium salt
5-fluorouridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component. It has a role as a drug metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and an organofluorine compound. It derives from a uridine 5'-monophosphate. Synonyms: 5F-UMP. Molecular formula: C9H12FN2O9P. Mole weight: 342.17 (free acid).
5-Fluorouridine-5'-triphosphate triethylammonium salt
5-Fluorouridine-5'-triphosphate triethylammonium salt, an indispensable compound within the field of biomedicine, serves as a pivotal reagent. Its essence lies in its ability to serve as a substrate for RNA synthesis, permitting the infusion of the vital anticancer agent, 5-fluorouracil, into RNA molecules. Synonyms: Uridine 5'-(tetrahydrogen triphosphate),5-fluoro-,compd with N,N-diethylethanamine(1:3)(9CI). Grades: 95%. Molecular formula: C33H74N6O15P3F. Mole weight: 906.89.
5-Fluorouridine (Standard)
5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of 5-fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 316-46-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-107856R.
5-(Hydroxymethyl)-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Synonyms: a-hydroxythymidine; 5-Hydroxymethyl-2'-deoxyuridine; alpha-Hydroxythymidine; 5-Hydroxymethyldeoxyuridine; HMdU; 5-HMdU; 2'-Deoxy-5-(hydroxymethyl)uridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-(2-hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 5116-24-5. Molecular formula: C10H14N2O6. Mole weight: 258.23.
5-Methyl-4'-thiouridine
5-Methyl-4'-thiouridine, a modified RNA base nucleoside, has been found to exhibit significant therapeutic potential against a variety of cancer types - notably leukemia and breast cancer - via its demonstrated ability to retard tumor growth and initiate programmed cell death in malignant cells. Further, this innovative compound has been shown to enhance the efficacy of fluorouracil and cytarabine, two commonly used chemotherapeutic drugs. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)-5-methyluracil; 1-(4'-Thio-beta-ribofuranosyl)thymine; Uridine, 5-methyl-4'-thio-; 1-Ribo-4'-thiothymine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 6741-71-5. Molecular formula: C10H14N2O5S. Mole weight: 274.29.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. Grades: ≥98% by HPLC. CAS No. 142246-63-7. Molecular formula: C39H46FN4O8P. Mole weight: 748.78.
ANX-510
ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44.
Barbituric acid
Barbituric acid (BA) may be used in the preparation of the corresponding hemiaminals, via chemoselective reduction in the presence of SmI2/H2O reagent. It may be used in the preparation of BA- modified conjugated carbon nitride nanosheets. Barbituric acid is a useful acid for organic and drug syntheses. Its dihydrate form can be synthesized from barbituric acid via crystallization from aqueous solution. Crystal structure of barbituric acid (in tautomeric form) has been investigated by a three dimensional fourier transform method. Its enol crystal form has been reported to be thermodynamically stable. Group: Biochemicals. Alternative Names: 2,4,6(1H,3H,5H)-Pyrimidinetrione; 1,2,3,4,5,6-Hexahydro-2,4,6-pyrimidinetrione; 2,4,6-Pyrimidinetriol; 2,4,6-Pyrimidinetrione; 2,4,6-Trihydroxypyrimidine; 2, 4, 6-Trioxohexa hydropyrimidine; 6-Hydroxyuracil; Hexahydropyrimidine-2,4,6-trione; Malonylurea; NSC 7889; Fluorouracil. Grades: Purified. CAS No. 67-52-7. Pack Sizes: 100g, 500g. US Biological Life Sciences.
Worldwide
Benzylacyclouridine
Benzylacyclouridine (BAU) is a potent and specific inhibitor of uridine phosphorylase, the first enzyme in the catabolism of uridine. Benzylacyclouridine inhibits the metabolic activity of UPP1 and the activity of UPP2. Benzylacyclouridine can modulate the cytotoxic side effects of 5-fluorouracil (5-FU) and its derivatives[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAU; 5-Benzylacyclouridine. CAS No. 82857-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106406.
Carmofur
Carmofur or HCFU is a pyrimidine analogue used as an antineoplastic agent. It is a derivative of fluorouracil. Uses: Antineoplastic agents. Synonyms: HCFU. Grades: >98%. CAS No. 61422-45-5. Molecular formula: C11H16FN3O3. Mole weight: 257.26.
Eniluracil
Eniluracil (5-Ethynyluracil) is an orally active dihydropyrimidine dehydrogenase ( DPD ) inhibitor. Eniluracil irreversibly inhibits DPD , increases the oral bioavailability of 5-fluorouracil to 100%, and facilitates the uniform absorption and toxicity of 5-fluorouracil. Eniluracil can be used in cancer research of combination with fluoropyrimidines (including 5-fluorouracil) [1] [2]. Eniluracil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Ethynyluracil; GW776C85. CAS No. 59989-18-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10533.
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