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Fluvastatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 93957-54-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
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Fluvastatin
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR) with IC50 of 8 nM. It belongs to a class of the statin drug and is structurally distinct from the fungal derivatives of this therapeutic class. It binds of the substrate HMG-CoA with Ki value of 0.3 nM but not with respect to binding of NADPH. It is marketed under the trade name Lescol® and is used to treat hypercholesterolemia and to prevent cardiovascular disease. It induces G2/M phase arrest and has antilipemic effect. Uses: Fluvastatin is used to treat hypercholesterolemia and to prevent cardiovascular disease. it has antilipemic effect. Synonyms: XU-62320; XU 62320; XU62320; Cranoc; Lescol; (+)-(3R,5S)-fluvastati; (E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid; 6-Heptenoic acid,7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-,[R*,S*-(E)]-. Grade: 99%. CAS No. 93957-54-1. Molecular formula: C24H26FNO4. Mole weight: 411.47.
Fluvastatin
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC 50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XU 62-320 free acid. CAS No. 93957-54-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-14664.
Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt
Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt is a metabolite of Fluvastatin, a synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: 7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxy-4,6-Heptadienoic Acid Sodium Salt. Grades: Highly Purified. CAS No. 1207963-21-0. Pack Sizes: 5mg. Molecular Formula: C24H23FNNaO3. US Biological Life Sciences.
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Fluvastatin-[d6]
Fluvastatin-[d6] is a deuterium labelled form of Fluvastatin. Fluvastatin can be used to treat hypercholesterolemia and to prevent cardiovascular disease. Synonyms: Fluvastatin D6. Grade: 95% by CP; 98% atom D. CAS No. 2249799-34-4. Molecular formula: C24H20D6FNO4. Mole weight: 417.5.
Fluvastatin-[d6] sodium salt
Fluvastatin-[d6] sodium salt is the labelled salt of Fluvastatin, which is a HMG-CoA reductase inhibitor and could be used as an antilipemic agent. Synonyms: Fluvastatin D6 sodium; (3R,5S,E)-7-(3-(4-fluorophenyl)-1-(propan-2-yl-1,1,1,3,3,3-d6)-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate, monosodium salt; (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl-d6)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; Fluindostatin-d6; XU 62-320-d6; Lescol-d6; Lipaxan-d6; Primexin-d6. Grade: 94% by CP; 99% atom D. Molecular formula: C24H19D6FNNaO4. Mole weight: 439.48.
Fluvastatin Degradation Product (diastereomeric mixture) is the various metabolites generated during the degradation process of Fluvastatin, which is a statin drug commonly prescribed for lowering cholesterol levels in patients with hyperlipidemia and cardiovascular diseases. Grade: > 95%. Molecular formula: C24H26FNO4. Mole weight: 411.48.
Fluvastatin Enone
Fluvastatin Enone is a notable synthetic compound extensively utilized in studying hypercholesterolemia and atherosclerosis. This multifaceted product exerts its influence as a high-efficiency inhibitor of HMG-CoA reductase, significantly studying the levels of low-density lipoprotein (LDL) cholesterol coursing through the circulatory system. Grade: > 95%. Molecular formula: C24H24FNO4. Mole weight: 409.46.
Fluvastatin EP Impurity G
Fluvastatin EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carbaldehyde. CAS No. 101125-34-2. Molecular formula: C18H16FNO. Mole weight: 281.32. Catalog: APB101125342.
Fluvastatin for System Suitability
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fluvastatin Hydroxy Diene Impurity
Fluvastatin Hydroxy Diene Impurity is an impurity of fluvastatin formulations, a drug used to mitigate hypercholesterolemia and subjugate the perils begotten by cardiovascular afflictions. Grade: > 95%. Molecular formula: C24H23FNO3Na. Mole weight: 415.44.
Fluvastatin impurity 10
Fluvastatin impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331643-17-4. Molecular formula: C24H23FNNaO4. Mole weight: 431.44. Catalog: APB1331643174.
Fluvastatin Ketone Sodium Salt
Fluvastatin Ketone Sodium Salt is an eminent chemical compound extensively employed in developing therapeutic agent for dyslipidemia and hypercholesterolemia. Functioning as a potent HMG-CoA reductase inhibitor, it efficaciously restrains the intricate biosynthesis of cholesterol and concurrently diminishes the levels of LDL cholesterol. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
A synthetic HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: Fluindostatin; XU 62-320; Lescol; Lipaxan; Primexin. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Fluvastatin lactone-mixture of four isomers
Fluvastatin lactone-mixture of four isomers is the isomers from Fluvastatin lactone, a drug for unequivocally treating the onset of cardiovascular pathologies. Grade: > 95%. Molecular formula: C24H24FNO3. Mole weight: 393.46.
Fluvastatin lactone (racemic mixture)
Fluvastatin lactone (racemic mixture) is an extensively applied compound employed for the research of dyslipidemia, a complex disorder specifically marked by the augmentation of cholesterol and triglyceride concentrations. This exceptional product aids in the inhibition of HMG-CoA reductase, subsequently leading to a decrease in cholesterol biosynthesand thus facilitating the effective control and research of hypercholesterolemia. Grade: > 95%. Molecular formula: C24H24FNO3. Mole weight: 393.46.
Fluvastatin methyl ester
Fluvastatin methyl ester. Group: Biochemicals. Alternative Names: (3R,5S,6E)-rel-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid methyl ester; [R*,S*-(E)]-(+/-)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid methyl ester. Grades: Highly Purified. CAS No. 93957-53-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C25H28FNO4. US Biological Life Sciences.
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Fluvastatin Methyl Ester
Fluvastatin Methyl Ester is an indispensable biomedical entity, demonstrating paramount significance in studying dyslipidemia. Through potent inhibition of HMG-CoA reductase, Fluvastatin Methyl Ester remarkably mitigates LDL cholesterol levels. Synonyms: AKOS015896075; AC-4521; (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester; 786710-21-2; Methyl (3R,5S,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate. Grade: > 95%. CAS No. 786710-21-2. Molecular formula: C25H28FNO4. Mole weight: 425.50.
Fluvastatin N-ethyl sodium salt (fluvastatin impurity)
Fluvastatin N-ethyl sodium salt (fluvastatin impurity). Group: Biochemicals. Alternative Names: [R*,S*-(E)]-(+/-)-7-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt; Fluvastatin impurity. Grades: Highly Purified. CAS No. 93936-64-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H23FNNaO4. US Biological Life Sciences.
Worldwide
Fluvastatin Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fluvastatin sodium
Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC 50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XU 62-320. CAS No. 93957-55-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-14664A.
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C24H25FNNaO4. CAS No. 93957-55-2. Prepack ID 20886355-1g. Molecular Weight 433.45. See USA prepack pricing.
A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; Fluindostatin; XU 62-320; Lescol; Lipaxan; Primexin. Grades: Highly Purified. CAS No. 93957-55-2. Pack Sizes: 100mg, 500mg, 1g, 5g. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences.
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Fluvastatin Sodium Salt-mixture of four isomers
Fluvastatin Sodium Salt is a complex amalgamation of four distinct isomers exhibiting a profound and meticulous ability to selectively inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
Fluvastatin t-Butyl Ester
Fluvastatin t-Butyl Ester is an intermediate for the preparation of (3R,5S)-Fluvastatin. Synonyms: tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate; 7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid 1,1-dimethylethyl ester; (3R,5S)-Fluvastatin tert-Butyl Ester; (3R,5S,6E)-7-[. Grade: > 95%. CAS No. 194934-96-8. Molecular formula: C28H34FNO4. Mole weight: 467.59.
(3R,5R)-Fluvastatin Sodium Salt
3R,5R)-Fluvastatin Sodium Salt is a prominent compound in the biomedical industry, aiding in the research of hypercholesterolemia. As a member of the esteemed statin class, it exerts its action by effectively inhibiting the pivotal enzyme HMG-CoA reductase. This paramount compound is frequently recommended to ameliorate LDL cholesterol levels. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
An intermediate for the preparation of (3R,5S)-Fluvastatin. Group: Biochemicals. Alternative Names: (4R,6S)-6-[(1E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 500731-91-9. Pack Sizes: 5mg. US Biological Life Sciences.
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(+)-3R,5S-Fluvastatin-d6 sodium salt
One of the isotopic labelled isomers of Fluvastatin, which is a HMG-CoA reductase inhibitor and could be used as an antilipemic agent. Synonyms: (+)-(3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt-d6. Molecular formula: C24H19FNO4D6.Na. Mole weight: 439.60.
(3R,5S)-Fluvastatin sodium
(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3R,5S)-XU 62-320. CAS No. 94061-80-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14664F.
A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Grades: Highly Purified. CAS No. 94061-80-0. Pack Sizes: 1mg. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences.
Worldwide
(+)-3R,5S-Fluvastatin sodium salt
(+)-3R,5S-Fluvastatin sodium salt is an extraordinary and powerful compound renowned for its exceptional ability to lower cholesterol levels. It stands as a paradigm-shifting breakthrough in the research of compound, specifically designed to study the detrimental influence of hyperlipidemia and hypercholesterolemia. Synonyms: (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid. Grade: > 95%. CAS No. 155229-75-7. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
(3R,5S)-Fluvastatin tert-Butyl Ester
An intermediate for the preparation of (3R,5S)-Fluvastatin. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 194934-96-8. Pack Sizes: 1mg. US Biological Life Sciences.
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(3S,5R)-Fluvastatin-[d6] sodium
(3S,5R)-Fluvastatin-[d6] sodium is the labelled isomer of Fluvastatin, which is a HMG-CoA reductase inhibitor and could be used as an antilipemic agent. Synonyms: (3S,5R)-Fluvastatin D6 sodium; (-)-(3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid-d6 Sodium Salt; (-)-3S,5R-Fluvastatin-d6 sodium salt; [R-[R*,S*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid-d6 Monosodium Salt; ent-Fluvastatin-d6 Sodium Salt. Grade: 98%. CAS No. 2249799-35-5. Molecular formula: C24H19D6FNNaO4. Mole weight: 439.48.
(-)-3s,5r-Fluvastatin sodium salt
(-)-3s,5r-Fluvastatin sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (-)-3S,5R-FLUVASTATIN SODIUM SALT;(3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Product Category: Heterocyclic Organic Compound. Appearance: Solid. CAS No. 155229-76-8. Molecular formula: C24H25FNNaO4. Mole weight: 433.45. Purity: 0.96. IUPACName: (3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid. Density: 1.23g/cm³. Product ID: ACM155229768. Alfa Chemistry ISO 9001:2015 Certified.
(-)-3S,5R-Fluvastatin sodium salt
(-)-3S,5R-Fluvastatin sodium salt is a product commonly employed to develop a cholesterol-lowering medication, specifically known for studying hypercholesterolemia and dyslipidemia. This sodium salt form enhances the solubility and bioavailability of Fluvastatin. Synonyms: (3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Grade: > 95%. CAS No. 94061-81-1. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
(3S,5R)-Fluvastatin sodium salt
(3S,5R)-Fluvastatin sodium salt. Group: Biochemicals. Alternative Names: (3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt. Grades: Highly Purified. CAS No. 155229-76-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H25FNNaO4. US Biological Life Sciences.
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(3S,5S)-Fluvastatin Sodium Salt
(3S,5S)-Fluvastatin Sodium Salt is an analogue of Fluvastatin (F601250). Synonyms: (S,S)-Fluvastatin Sodium Salt; [S-[R*,R*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt. Grade: > 95%. CAS No. 194935-01-8. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
rac 5-Keto Fluvastatin
rac 5-Keto Fluvastatin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1160169-39-0. Pack Sizes: 5MG. IUPAC Name: (E)-7-[3-(4-fluorophenyl)-1-isopropyl-indol-2-yl]-3-hydroxy-5-oxo-hept-6-enoic acid. Molecular formula: C24H24FNO4. Mole weight: 409.45. Catalog: APS1160169390A. SMILES: CC(C)n1c(\C=C\C(=O)CC(O)CC(=O)O)c(c2ccc(F)cc2)c3ccccc13. Format: Neat. Shipping: Room Temperature.
1-Ethyl-3-(4-fluorophenyl)-1H-indole
1-Ethyl-3-(4-fluorophenyl)-1H-indole is an intermediate in the synthesis of Fluvastatin (F601250) related derivatives and impurities. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H14FN. US Biological Life Sciences.
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1-Isopropyl-3-(4-fluorophenyl)indole
Fluvastatin derivative. Group: Biochemicals. Alternative Names: 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole. Grades: Highly Purified. CAS No. 93957-49-4. Pack Sizes: 1g. US Biological Life Sciences.
Fluvastatin intermediate. Group: Biochemicals. Alternative Names: 3-(4-Fluorophenyl)-1-isopropyl-1H-indole-2-carboxaldehyde; 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carboxaldehyde. Grades: Highly Purified. CAS No. 101125-34-2. Pack Sizes: 100mg. US Biological Life Sciences.
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1-Isopropyl-3-(4-fluorophenyl)indole-d7
1-Isopropyl-3-(4-fluorophenyl)indole-d7 is an isotope labelled derivative of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C17H9D7FN. US Biological Life Sciences.
Worldwide
3-(4-Fluorophenyl)-1H-indole
3-(4-Fluorophenyl)-1H-indole is a reagent used in the synthesis indole based sigma receptor ligands. Also used in the preparation of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Grades: Highly Purified. CAS No. 101125-32-0. Pack Sizes: 2.5g, 5g. Molecular Formula: C14H10FN. US Biological Life Sciences.
3-Amino-α -[[[2- (4-methoxy-3-methylphenyl) -1-methylethyl] (phenylmethyl) amino]methyl]-4- (phenylmethoxy) benzenemethanol is an intermediate in the synthesis of (3R,5S)-Fluvastatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1616967-24-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C33H38N2O3, Molecular Weight: 510.67. US Biological Life Sciences.
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6a-Hydroxy Paclitaxel
6α-hydroxy Paclitaxel is a primary metabolite of the anticancer compound paclitaxel (Item No. 10461), produced by the action of the cytochrome P450 isoform CYP2C8.1,2 The generation of 6α-hydroxy paclitaxel by CYP2C8 can be impacted by other drugs (e.g., fluvastatin, Item No. 10010334) or dietary components that interefere with CYP2C8 activity, as well as by CYP2C8 genetic polymorphisms.3,4,5. Group: Biochemicals. Alternative Names: 6α-hydroxy Taxol; βS-(benzoylamino)-αR-hydroxy-(2aR, 3S, 4R, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS, )-6, 12b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-3, 4, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl ester-benzenepropanoic acid. Grades: Highly Purified. CAS No. 153212-75-0. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 869.91. US Biological Life Sciences.
An impurity of Fluvastatin. Fluvastatin is a statin medication primarily used to treat high cholesterol and reduce the risk of cardiovascular events. Synonyms: (E)-3-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-2-propenal; 2-Propenal, 3-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-, (E)-; Fluvastatin Impurity 17. Grade: ≥95%. CAS No. 93937-37-2. Molecular formula: C19H16FNO. Mole weight: 293.33.
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