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| Product | Description | |
|---|---|---|
| FMK | FMK is a an irreversible RSK2 kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK. Uses: Scientific research. Group: Signaling pathways. CAS No. 821794-92-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101A. |  |
| FMK | FMK is a potent, highly specific and irreversible ribosomal s6 kinase (RSK) inhibitor that covalently modifies the C-terminal kinase domain of RSK. Its IC50 value is 15 nM. It could prevent the activation of the N-terminal kinase domain of RSK by the C-terminal kinase domain, but does not affect the activity of the N-terminal domain. It binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. It induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells. It is used to determine the role of RSK as a direct regulator of NHE1 phosphorylation and sarcolemmal NHE activity in this cell type, in response to 1-adrenergic stimulation. Uses: Fmk could prevent the activation of the n-terminal kinase domain of rsk by the c-terminal kinase domain, but does not affect the activity of the n-terminal domain. it is used to determine the role of rsk as a direct regulator of nhe1 phosphorylation and sarcolemmal nhe activity in this cell type, in response to 1-adrenergic stimulation. Synonyms: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone; RSK2 kinase inhibitor. Grade: >98%. CAS No. 821794-92-7. Molecular formula: C18H19FN4O2. Mole weight: 342.37. |  |
| FMK 9a | FMK 9a is a covalent autophagin-1 inhibitor (IC50 = 80 and 73 μM in FRET and LRA assay). Synonyms: FMK-9a; FMK 9a; FMK9a; N-[(2S)-1-[(3-fluoro-2-oxopropyl)amino]-1-oxo-3-phenylpropan-2-yl]naphthalene-1-carboxamide. CAS No. 1955550-51-2. Molecular formula: C23H21FN2O3. Mole weight: 392.42. | |
| FMK-MEA | FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor. CAS No. 1414811-15-6. Molecular formula: C21H26FN5O2. Mole weight: 399.47. | |
| FMK-MEA | FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414811-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-52101C. | |
| Biotin-AEVD-FMK | Biotin-AEVD-FMK is a biotin-labeled caspase-10 inhibitor that can be used as a probe for detecting caspase-10 by biotin ligand. Synonyms: Biotin-A-E(OMe)-V-Asp(OMe)-FMK; Biotin-Ala-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C30H47FN6O10S. Mole weight: 702.80. | |
| Biotin-ASTD-FMK | Biotin-ASTD-FMK is a biotin-labeled inhibitor of endothelial monocyte-activated polypeptide II (EMAP II), which can be used as a probe for detecting EMAP II by biotin ligand. Synonyms: Biotin-Ala-Ser-Thr-Asp(OMe)-Fluoromethylketone; Biotin-ASTD-Fluoromethylketone; Biotin-ASTD(OMe)-fmk. Grade: ≥95%. Molecular formula: C26H41FN6O10S. Mole weight: 648.70. | |
| Biotin-ATAD-FMK | Biotin-ATAD-FMK is a biotin-labeled caspase-12 inhibitor, which can be used as a probe for detecting caspase-12 by biotin ligand. Synonyms: Biotin-ATAD-FMK; Biotin-ATAD-fluoromethylketone. Grade: ≥95%. Molecular formula: C26H41FN6O9S. Mole weight: 632.71. | |
| Biotin-DEVD-FMK | Biotin-DEVD-FMK is a biotin-labeled caspase-3 inhibitor that can be used as a probe for detecting caspase-3 by biotin ligand. Synonyms: Biotin-D(OMe)E(OMe)VD(OMe)-FMK; Biotin-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C32H49FN6O12S. Mole weight: 760.83. | |
| Biotin-DQMD-FMK | Biotin-DQMD-FMK is a biotin-labeled caspase-3 inhibitor that can be used as a probe for detecting caspase-3 by biotin ligand. Synonyms: Biotin-Asp(OMe)-Gln-Met-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C31H48FN7O11S2. Mole weight: 777.88. | |
| Biotin-FA-FMK | Biotin-FA-FMK is a biotin-labeled cysteine protease inhibitor that specifically suppresses cathepsins B, L, and S, cruzain, papain and caspases-2, -3, -6, and -7 in live cells. It can be used as a probe for detecting these enzymes by biotin ligand. Synonyms: Biotin-Phe-DL-Ala-fluoromethylketone; Biotin-Phe-DL-Ala-CH2F. Grade: ≥95%. Molecular formula: C23H31FN4O4S. Mole weight: 478.58. | |
| Biotin-FF-FMK | Biotin-FF-FMK is a biotin-labeled cathepsin inhibitor that selectively suppresses cathepsin B and cathepsin L. Synonyms: Biotin-Phe-Phe-CH2F; Biotin-Phe-Phe-Fluoromethylketone. Grade: ≥95%. Molecular formula: C29H35FN4O4S. Mole weight: 554.68. | |
| Biotin-IETD-FMK | Biotin-IETD-FMK is a biotin-labeled caspase-8 inhibitor that specifically suppresses caspase-8 and tumor apoptosis. Synonyms: Biotin-IE(OMe)TD(OMe)-FMK; Biotin-Ile-Glu(OMe)-Thr-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C32H51FN6O11S. Mole weight: 746.85. | |
| Biotin-LEED-FMK | Biotin-LEED-FMK is a biotin-labeled caspase-13 inhibitor that can be used as a probe for detecting caspase-13 by biotin ligand. Synonyms: Biotin-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C34H53FN6O12S. Mole weight: 788.89. | |
| Biotin-LEVD-FMK | Biotin-LEVD-FMK is a biotin-labeled caspase-4 inhibitor that can be used as a probe for detecting caspase-4 by biotin ligand. Synonyms: Biotin-LE(OMe)VD(OMe)-FMK; Biotin-Leu-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C33H53FN6O10S. Mole weight: 744.88. | |
| Biotin-LLY-FMK | Biotin-LLY-FMK is a biotin-labeled calpain inhibitor that can be used as a probe for detecting calpain II and cathepsin L by biotin ligand. Synonyms: Biotin-Leu-Leu-Tyr-Fluoromethylketone. Grade: ≥95%. Molecular formula: C32H48FN5O6S. Mole weight: 649.82. | |
| Biotin-VAD-FMK | Biotin-VAD-FMK is a biotin-labeled pan-caspase inhibitor that can be used as a probe for detecting caspases by biotin ligand. Synonyms: Biotin-Val-Ala-Asp(OMe)-fluoromethyl ketone; bVAD-fmk; Biotin-VAD(OMe)-FMK. Grade: ≥95%. CAS No. 1135688-15-1. Molecular formula: C30H49FN6O8S. Mole weight: 672.81. | |
| Biotin-VDVAD-FMK | Biotin-VDVAD-FMK is a biotin-labeled caspase-2 inhibitor that can be used as a probe for detecting caspase-2 by biotin ligand. Synonyms: Biotin-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C34H54FN7O11S. Mole weight: 787.90. | |
| Biotin-YVAD-FMK | Biotin-YVAD-FMK is a biotin-labeled caspase-1 inhibitor that can be used as a probe for detecting caspase-1 by biotin ligand. Synonyms: Biotin-Tyr-Val-Ala-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C33H47FN6O9S. Mole weight: 722.83. | |
| Boc-A-FMK | Boc-A-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Synonyms: Boc-A-Fluoromethyl Ketone; Boc-Ala-FMK; tert-butyl (S)-(4-fluoro-3-oxobutan-2-yl)carbamate. Grade: ≥95%. Molecular formula: C9H16FNO3. Mole weight: 205.23. | |
| Boc-D-FMK | BOC-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that fully inhibits the pro-apoptotic effect of tumor necrosis factor-α (TNFα). It has been found to reduce the activation of nuclear factor kappa light chain enhancer of activated B cells (NF-kB), suppress the phosphorylation of subunit nuclear factor kappa light polypeptide gene enhancer in B cells inhibitor α (IkBα) and inhibit TNF-induced expression of intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1). Moreover, it has also effectively attenuated the hepatocyte apoptosis in bile duct-ligated rats potentially improving the survival rates. Uses: Caspase inhibitors. Synonyms: Boc-Asp(OMe)-fluoromethyl ketone; Caspase Inhibitor 3; N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone; BAF; Boc-D-Fluoromethyl Ketone; Boc-D(OMe)-FMK; 3S-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid, methyl ester; Caspase Inhibitor III. Grade: 95%. CAS No. 187389-53-3. Molecular formula: C11H18FNO5. Mole weight: 263.26. | |
| Boc-E-FMK | Boc-E-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Synonyms: Boc-Glu-FMK; Boc-E-Fluoromethyl Ketone; Boc-E(OMe)-FMK. Grade: ≥95%. Molecular formula: C12H20FNO5. Mole weight: 277.29. | |
| Boc-T-FMK | Boc-T-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Synonyms: Boc-T-Fluoromethyl Ketone. Grade: ≥95%. Molecular formula: C10H18FNO4. Mole weight: 235.26. | |
| Caspase-12 Inhibitor Z-ATAD-FMK | Caspase-12 Inhibitor Z-ATAD-FMK is a cell-permeable peptide inhibitor of Caspase 12. Grade: >95%. Molecular formula: C24H33N4O9F. Mole weight: 540.54. | |
| Caspase-13 Inhibitor Z-LEED-FMK | Caspase-13 Inhibitor Z-LEED-FMK is a synthetic peptide inhibitor that inhibits the activity of caspase-13 and related caspases. Grade: >95%. Molecular formula: C32H45FN4O12. Mole weight: 696.7. | |
| Caspase-1/ICE Inhibitor Z-WEHD-FMK | Z-WEHD-FMK is an inhibitor of caspase-1, caspase-5 and cathepsin B, which can inhibit cell apoptosis in a variety of biological systems. Synonyms: CASPASE-1 INHIBITOR TFA SALT; Z-WEHD-FMK-TFA; Z-TRP-GLU(OME)-HIS-ASP(OME)-FMK-TFA. Grade: >99%. CAS No. 210345-00-9. Molecular formula: C37H42FN7O11. Mole weight: 763.78. | |
| Caspase-6 Inhibitor Z-VEID-FMK | Caspase-6 Inhibitor Z-VEID-FMK is a caspase-6 inhibitor. Synonyms: Z-VEID-FMK, caspase-6 inhibitor. Grade: >98%. Molecular formula: C31H45FN4O10. Mole weight: 652.9. | |
| Caspase-9 Inhibitor Z-LEHD-FMK | Caspase-9 Inhibitor Z-LEHD-FMK is a synthetic peptide inhibitor that inhibits the activity of caspase-9 and related caspase. Grade: >98%. CAS No. 210345-04-3. Molecular formula: C32H43FN6O10. Mole weight: 690.7. | |
| FICT-FF-FMK | FICT-FF-FMK is a fluorescein isothiocyanate (FITC)-conjugated inhibitor of cathepsin B and cathepsin L, which can be used for detecting cathepsin B and cathepsin L in live cells. Synonyms: FICT-Phe-Phe-FMK; FICT-Phe-Phe-Fluoromethylketone. Grade: >95%. Molecular formula: C41H34FN3O6S. Mole weight: 715.80. | |
| Fitc-AEVD-FMK | FITC-AEVD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-10 inhibitor that can be used as a marker for detecting caspase-10 in live cells. Synonyms: FITC-A-E(OMe)-V-Asp(OMe)-FMK; FITC-Ala-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C41H44FN5O13S. Mole weight: 865.88. | |
| Fitc-ASTD-FMK | FITC-ASTD-FMK is a fluorescein isothiocyanate (FITC)-conjugated inhibitor of endothelial monocyte-activated polypeptide II (EMAP II), which can be used as a marker for detecting EMAP II in live cells. Synonyms: FITC-Ala-Ser-Thr-Asp(OMe)-Fluoromethylketone; FITC-ASTD(OMe)-fmk; FITC-Ala-Ser-Thr-Asp(OMe)-CH2F. Grade: ≥95%. Molecular formula: C37H38FN5O13S. Mole weight: 811.79. | |
| Fitc-ATAD-FMK | FITC-ATAD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-12 inhibitor, which can be used as a marker for detecting caspase-12 in live cells. Synonyms: FITC-ATAD-FMK; FITC-ATAD-fluoromethylketone. Grade: ≥95%. Molecular formula: C37H38FN5O12S. Mole weight: 795.79. | |
| Fitc-DEVD-FMK | FITC-DEVD-FMK is a cell-permeant caspase-3 inhibitor conjugated with fluorescein isothiocyanate (FITC) that can be used as a marker for detecting caspase-3 in live cells. Synonyms: FITC-Asp-Glu-Val-Asp-fluoromethyl ketone; FITC-D(OMe)-E(OMe)-VD(OMe)-FMK. Grade: ≥95%. Molecular formula: C43H46FN5O15S. Mole weight: 923.91. | |
| Fitc-DQMD-FMK | FITC-DQMD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-3 inhibitor that can be used as a marker for detecting caspase-3 in live cells. Synonyms: FITC-Asp(OMe)-Gln-Met-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C42H45FN6O14S2. Mole weight: 940.97. | |
| Fitc-FA-FMK | FITC-FA-FMK is a fluorescein isothiocyanate (FITC)-conjugated cysteine protease inhibitor, which can be used as a marker for detecting cysteine proteases including cathepsins B, L, and S, cruzain, papain as well as some caspases in live cells. Synonyms: FITC-Phe-DL-Ala-fluoromethylketone; FITC-Phe-DL-Ala-CH2F. Grade: ≥95%. Molecular formula: C34H28FN3O7S. Mole weight: 641.67. | |
| Fitc-FF-FMK | Fitc-FF-FMK is a biotin-labeled cathepsin inhibitor that selectively suppresses cathepsin B and cathepsin L. Synonyms: FITC-Phe-Phe-CH2F; FITC-Phe-Phe-fluoromethyl ketone. Grade: ≥95%. Molecular formula: C40H32FN3O7S. Mole weight: 717.77. | |
| Fitc-IETD-FMK | FITC-IETD-FMK is a cell-permeant caspase-8 inhibitor conjugated with fluorescein isothiocyanate (FITC) that can be used as a marker for detecting caspase-8 in live cells. Synonyms: FITC-Ile-Glu-Thr-Asp-fluoromethyl ketone; FITC-I-E(OMe)-TD(OMe)-FMK. Grade: ≥95%. Molecular formula: C43H48FN5O14S. Mole weight: 909.94. | |
| Fitc-LEED-FMK | FITC-LEED-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-13 inhibitor that can be used as a marker for detecting caspase-13 in live cells. Synonyms: FITC-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C45H50FN5O15S. Mole weight: 951.97. | |
| Fitc-LEVD-FMK | FITC-LEVD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-4 inhibitor that can be used as a marker for detecting caspase-4 in live cells. Synonyms: FITC-LE(OMe)VD(OMe)-FMK; FITC-Leu-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C44H50FN5O13S. Mole weight: 907.96. | |
| Fitc-LLY-FMK | FITC-LLY-FMK is a fluorescein isothiocyanate (FITC)-conjugated calpain inhibitor that can be used as a marker for detecting calpain II and cathepsin L in live cells. Synonyms: FITC-Leu-Leu-Tyr-Fluoromethylketone. Grade: ≥95%. Molecular formula: C43H45FN4O9S. Mole weight: 812.91. | |
| Fitc-VAD-FMK | FITC-VAD-FMK is a cell-permeant pan-caspase inhibitor conjugated with fluorescein isothiocyanate (FITC) that can be used as a marker for detecting caspases in live cells. Synonyms: FITC-Val-Ala-Asp-fluoromethyl ketone; FITC-VAD(OMe)-FMK; methyl (S)-3-((S)-2-((S)-2-(3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)thioureido)-3-methylbutanamido)propanamido)-5-fluoro-4-oxopentanoate. Grade: ≥95%. Molecular formula: C35H35FN4O10S. Mole weight: 722.74. | |
| Fitc-VDVAD-FMK | FITC-VDVAD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-2 inhibitor that can be used as a marker for detecting caspase-2 in live cells. Synonyms: FITC-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C45H51FN6O14S. Mole weight: 950.99. | |
| Fitc-YVAD-FMK | FITC-YVAD-FMK is a fluorescein isothiocyanate (FITC)-conjugated caspase-1 inhibitor that can be used as a marker for detecting caspase-1 in live cells. Synonyms: FITC-Tyr-Val-Ala-Asp(OMe)-Fluoromethylketone. Grade: ≥95%. Molecular formula: C44H44FN5O12S. Mole weight: 885.92. | |
| Z-AEVD-FMK | Z-AEVD-FMK is a cell-permeant and irreversible caspase-10 inhibitor. It is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Synonyms: Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone; (5S,8S,11S,14S)-Methyl 14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,1 3-tetraazahexadecan-16-oate; Z-A-E(OMe)-V-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK. Grade: ≥95%. CAS No. 1135688-47-9. Molecular formula: C28H39FN4O10. Mole weight: 610.63. | |
| Z-AEVD-FMK | Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 1135688-47-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125305. | |
| Z-ASTD-FMK | Z-ASTD-FMK is a cell-permeant and irreversible inhibitor of endothelial monocyte-activated polypeptide II (EMAP II). Synonyms: EMAP II inhibitor; Z-Ala-Ser-Thr-Asp(OMe)-Fluoromethylketone; Z-ASTD(OMe)-fmk; Cbz-Ala-Ser-Thr-Asp(OMe)-CH2F. Grade: ≥95%. Molecular formula: C24H33FN4O10. Mole weight: 556.54. | |
| Z-ATAD-FMK | Z-ATAD-FMK is a cell-permeant caspase-12 inhibitor. It was shown to suppress annular cell apoptosis in vitro. Synonyms: Caspase-12 Inhibitor; Z-ATAD-FMK; Z-ATAD-fluoromethylketone. Grade: ≥95%. Molecular formula: C24H33FN4O9. Mole weight: 540.54. | |
| Z-DEVD-FMK | Z-DEVD-FMK Inhibitor. Uses: Scientific use. Product Category: T6005. CAS No. 210344-95-9. |  |
| Z-DEVD-FMK | Z-DEVD-FMK is a cell-permeant, irreversible caspase-3 inhibitor that can be used as an anaesthetic agent. It has been shown to suppress tumor cell apoptosis. Uses: Cysteine proteinase inhibitors. Synonyms: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK; Caspase-3 Inhibitor; Z-D(OMe)E(Ome)VD(OMe)-FMK; benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone; Caspase-3 Inhibitor II; Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; Z-DEVD-fluoromethylketone. Grade: ≥95%. CAS No. 210344-95-9. Molecular formula: C30H41FN4O12. Mole weight: 668.67. | |
| Z-DEVD-FMK | Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 210344-95-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12466. | |
| Z-DQMD-FMK | Z-DQMD-FMK has been found to be a Caspase-3 inhibitor and could induce small cell lung cancer cell death in vitro. Synonyms: Z-D(OMe)QMD(OMe)-fmk; benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone; Z-Asp(OMe)-Gln-Met-Asp(OMe) fluoromethyl ketone; L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-glutaminyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; methyl (5S,8S,11S,14S)-8-(3-amino-3-oxopropyl)-14-(2-fluoroacetyl)-5-(2-methoxy-2-oxoethyl)-11-(2-(methylthio)ethyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. Grade: ≥95%. CAS No. 767287-99-0. Molecular formula: C29H40FN5O11S. Mole weight: 685.72. | |
| Z-FA-FMK | Z-FA-FMK ((1S)-Z-FA-FMK) is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs). Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (1S)-Z-FA-FMK. CAS No. 197855-65-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0109A. | |
| Z-FA-FMK | Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibitits papain and cruzain. Group: Biochemicals. Grades: Highly Purified. CAS No. 197855-65-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H23FN2O4, Molecular Weight: 386.42. US Biological Life Sciences. |  Worldwide |
| Z-FF-FMK | Z-FF-FMK is a cell-permeant and irreversible inhibitor of cathepsin B and cathepsin L. Synonyms: Cathepsin L Inhibitor I; Z-Phe-Phe-CH2F; Z-Phe-Phe-fluoromethyl ketone. Grade: ≥95%. CAS No. 105608-85-3. Molecular formula: C27H27FN2O4. Mole weight: 462.52. | |
| Z-IETD-FMK | Z-IETD-FMK Inhibitor. Uses: Scientific use. Product Category: T7019. CAS No. 210344-98-2. | |
| Z-IETD-FMK | Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. Z-IETD-FMK inhibits T cell proliferation induced by PHA or anti-CD3 plus anti-CD28 without toxicity of resting T cells. Synonyms: caspase-8 inhibitor; Z-IE(OMe)TD(OMe)-FMK; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F; Z-Ile-Glu(OMe)-Thr-Asp(OMe) fluoromethylketone; N-benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone. Grade: ≥95%. CAS No. 210344-98-2. Molecular formula: C30H43FN4O11. Mole weight: 654.69. | |
| Z-IETD-FMK | Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor[1]. Z-IETD-FMK is also a granzyme B inhibitor[5]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-IE(OMe)TD(OMe)-FMK. CAS No. 210344-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101297. | |
| Z-LEED-FMK | Z-LEED-FMK is a cell-permeant and irreversible caspase-13 inhibitor. Synonyms: Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-FMK; Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-Fluoromethylketone; methyl (5S,8S,11S,14S)-14-(2-fluoroacetyl)-5-isobutyl-8,11-bis(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. Grade: ≥95%. Molecular formula: C32H45FN4O12. Mole weight: 696.72. | |
| Z-LEHD-FMK | Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma[1][2][3]. Uses: Scientific research. Group: Peptides. CAS No. 210345-04-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1010. | |
| Z-LEVD-FMK | Z-LEVD-FMK is a cell-permeable caspase-4 inhibitor. Z-LEVD-FMK blocks ER stress-induced apoptosis in cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135688-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128707. | |
| Z-LEVD-FMK | Z-LEVD-FMK is a cell-permeant and irreversible caspase-4 inhibitor. Synonyms: Z-LE(OMe)VD(OMe)-FMK; Z-Leu-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; Cbz-Leu-Glu(OMe)-Val-Asp(OMe)-CH2F; Caspase 4 inhibitor. Grade: ≥95%. CAS No. 1135688-25-3. Molecular formula: C31H45FN4O10. Mole weight: 652.72. | |
| Z-LLY-FMK | Z-LLY-FMK is a cell-permeant and irreversible calpain inhibitor that is selective for calpain II, and also exhibits inhibitory effect against cathepsin L. It was shown to suppress hepatocyte apoptosis after bile duct ligation in rat. Synonyms: Calpain Inhibitor IV; Z-Leu-Leu-Tyr-FMK; Z-Leu-Leu-Tyr-Fluoromethylketone; N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide. Grade: ≥95%. CAS No. 133410-84-1. Molecular formula: C30H40FN3O6. Mole weight: 557.66. | |
| Z-VAD-FMK | solid. Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| Z-VAD-FMK | Z-VAD-FMK Inhibitor. Uses: Scientific use. Product Category: T7020. CAS No. 161401-82-7. | |
| Z-VAD-FMK | Z-VAD-FMK is a broad spectrum pan-caspase inhibitor that inhibits the intracellular activation of caspase-like proteases. Synonyms: Z-VAD (OMe)-FMK; Caspase Inhibitor I. Grade: >98.0%. CAS No. 187389-52-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49. | |
| Z-VAD-FMK | Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor, which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-VAD(OH)-FMK. CAS No. 161401-82-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16658B. | |
| Z-VAD-FMK (Cell permeable) | Cell-permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3-induced cells. Used in apoptosis and inflammasome studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 187389-52-2, 634911-81-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H30FN3O7. US Biological Life Sciences. | Worldwide |
| Z-VAD(OH)-FMK | Z-VAD(OH)-FMK, also known as Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone, is an irreversible tripeptide inhibitor of all caspases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-VAD(OH)-FMK; Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 161401-82-7. Molecular formula: C21H28FN3O7. Mole weight: 453.47. Purity: >98%. IUPACName: (5S,8S,11S)-11-(2-fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oic acid. Canonical SMILES: O=C(O)C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O. Product ID: ACM161401827. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Z-VAD(OMe)-FMK | Z-VAD(OMe)-FMK Inhibitor. Uses: Scientific use. Product Category: T6013. CAS No. 187389-52-2. | |
| Z-VAD(OMe)-FMK | Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor[1]. Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Val-Ala-Asp(OMe)-FMK. CAS No. 187389-52-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16658. | |
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