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Product
Fmoc-(Dmb)Gly-OH Fmoc-(Dmb)Gly-OH is an excellent reagent for enhancing synthetic efficiency of glycine-containing peptides by Fmoc SPPS.Like the analogous Hmb derivative Fmoc-(FmocHmb)Gly-OH, the use of this derivative prevents aggregation during chain assemby, thereby leading to faster and more predictable acylation and deprotection reactions. Furthermore, it can prevent aspartimide formation when used to introduce a Gly immediately before an Asp residue and help promote cyclization of Gly-containing peptides. The analogous (Tmob)Gly derivative has been used by Bayer and colleagues to prepare a 64-residue transmembrane peptide in remarkable purity. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-(Dmb)Gly-OH, N-α-Fmoc-N-α-(2, 4-dimethoxybenzyl)-glycine. Product Category: Amino Acids. CAS No. 166881-42-1. Mole weight: 447.48. Product ID: ACM166881421. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Fmoc-(Dmb)Gly-OH Synonyms: Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH. Grades: 95%. CAS No. 166881-42-1. Molecular formula: C26H25NO6. Mole weight: 447.5. BOC Sciences 4
Fmoc-Asp(OtBu)-(Dmb)Gly-OH Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction. This derivative also completely inhibits aspartimide formation. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-(Dmb)Gly-OH, N-α-Fmoc-β-O-t.-butyl-L-aspartyl-N-α-(2,4-dimethoxybenzyl)-glycine. Product Category: Amino Acids. CAS No. 900152-72-9. Mole weight: 618.67. Product ID: ACM900152729. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Fmoc-Gly-(Dmb)Gly-OH Fmoc-Gly-(Dmb)Gly-OH. Group: Biochemicals. Grades: Reagent Grade. CAS No. 848861-65-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
Fmoc-Gly-(Dmb)Gly-OH Synonyms: Nα-Fmoc-L-glycyl-Nα-(2, 4-dimethoxybenzyl)glycine; 2-(2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-N-(2,4-Dimethoxybenzyl)Acetamido)Acetic Acid. CAS No. 848861-65-4. Molecular formula: C28H28N2O7. Mole weight: 504.5. BOC Sciences 5

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