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N-Fmoc-L-glutamic acid is an N-Fmoc-protected form of L-Glutamic acid. L-Glutamic acid is a non-essential amino acid that is important to the mammalian central nervous system. L-Glutamic acid is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed 'hepatic coma'). Synonyms: Fmoc-L-Glu-OH; N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-glutamic acid; N-Fmoc-L-glutamic AcidFmoc-Glu-OH; (S) -2- ( ( ( (9H-Fluoren-9-yl) methoxy) carbonyl) amino) pentanedioic acid; N-Fmoc-L-glutamic Acid; FMOC-GLU-OH. Grades: ≥ 98% (HPLC). CAS No. 121343-82-6. Molecular formula: C20H19NO6. Mole weight: 369.38.
Fmoc-L-glutamic acid alpha-9-fluorenylmethyl ester. Group: Biochemicals. Alternative Names: Fmoc-L-Glu-OFm. Grades: Highly Purified. CAS No. 200616-18-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
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Fmoc-L-glutamic acid α-allyl ester
Allyl esters are useful carboxy protecting groups in the synthesis of various cyclic peptides glycopeptides. Allyl esters are cleaved quantitatively under mild conditions using Pd(0) catalyst. Synonyms: Fmoc-L-Glu-OAll; (S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(allyloxy)-5-oxopentanoic acid; Fmoc-Glu-OAll; Fmoc-L-glutamic acid alpha-allyl ester; L-Fmoc-Glu-OAll; Fmoc-Glu-OAllyl. Grades: ≥ 98% (HPLC). CAS No. 144120-54-7. Molecular formula: C23H23NO6. Mole weight: 409.43.
Fmoc-L-glutamic acid a-tert-butyl ester 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Fmoc-L-glutamic acid g -2-phenylisopropyl ester
The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM, making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS. Synonyms: Fmoc-L-Glu(2-phenylisopropyloxy)-OH; Fmoc-L-glutamic acid 5-(2-phenylisopropyl) ester; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-(2-phenylpropan-2-yloxy)pentanoic acid. Grades: ≥ 99% (Chiral HPLC, HPLC). CAS No. 200616-39-3. Molecular formula: C29H29NO6. Mole weight: 487.56.
Fmoc-L-glutamic acid g -2-phenylisopropyl ester 98+% (HPLC)
Fmoc-L-glutamic acid g -2-phenylisopropyl ester 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
The ODmab group is an excellent protecting group for carboxylic acids. It is orthogonal to both acid. Synonyms: Fmoc-L-Glu(ODmab)-OH; (2S)-5-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methoxy]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid. Grades: ≥ 99% (HPLC). CAS No. 268730-86-5. Molecular formula: C40H44N2O8. Mole weight: 680.80.
Fmoc-L-glutamic acid γ-9-fluorenylmethyl ester
Fmoc-L-glutamic acid γ-9-fluorenylmethyl ester. Group: Biochemicals. Alternative Names: Fmoc-L-Glu(OFm)-OH; Fmoc-L-glutamic acid 5-(9-fluorenylmethyl) ester. Grades: Highly Purified. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
An excellent tool for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS. The 2-PhiPr group can be selectively removed on the resin with 1% TFA in DCM in the presence of the standard t-butyl-based side-chain protecting groups. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu-O-2-PhiPr, N-α-Fmoc-L-glutamic acid α-2-phenylisopropyl ester. Product Category: Amino Acids. CAS No. 207305-97-3. Mole weight: 487.54. Product ID: ACM207305973-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu(O-2-PhiPr)-OH
Quasi-orthogonally-protected Glu derivative. The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM , making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS. or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(Mtt) and Glu(O-2-PhiPr) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu(O-2-PhiPr)-OH, N-α-Fmoc-L-glutamic acid γ-2-phenylisopropyl ester. Product Category: Amino Acids. CAS No. 200616-39-3. Mole weight: 487.54. Product ID: ACM200616393-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu-OAll
Orthogonally-protected building block for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS.The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph3P)4/ CHCl3/AcOH/NMM, thereby facilitating the synthesis of branched esters and amides, and lactones and lactams incorporating a glutamyl unit. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu-OAll, N-α-Fmoc-L-glutamic acid α-allyl ester. Product Category: Amino Acids. CAS No. 144120-54-7. Molecular formula: C23H23NO6. Mole weight: 409.43. Product ID: ACM144120547. Alfa Chemistry ISO 9001:2015 Certified. Categories: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-glutamic-acid-alpha allyl ester.
Fmoc-Glu-OBzl
Building block for introduction of aspartic acid bearing TFA-labile benzyl ester protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu-OBzl, N-α-Fmoc-L-glutamic acid α-benzyl ester. Product Category: Amino Acids. CAS No. 122350-52-1. Mole weight: 459.49. Product ID: ACM122350521-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu(OBzl)-OH
Building block for introduction of glutamic acid bearing TFA-labile benzyl ester side-chain protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu(OBzl)-OH, N-α-Fmoc-L-glutamic acid γ-benzyl ester. Product Category: Amino Acids. CAS No. 123639-61-2. Mole weight: 459.49. Product ID: ACM123639612. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID10553436.
Fmoc-Glu-ODmab
Quasi-orthogonally-protected Glu derivative. The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF , making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS. or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu-ODmab, N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester. Product Category: Amino Acids. CAS No. 172611-75-5. Mole weight: 680.79. Product ID: ACM172611755. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu-OtBu
Selectively protected building block for library synthesis or the preparation of γ-glutamyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the γ-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters, amides, lactams and lactones containing the glutamyl unit. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu-OtBu, N-α-Fmoc-L-glutamic acid α-t.-butyl ester. Product Category: Amino Acids. CAS No. 84793-07-7. Molecular formula: C24H27NO6. Mole weight: 425.47. Product ID: ACM84793077. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu(OtBu)-OH
Fmoc-Glu(OtBu)-OH. Group: Biochemicals. Alternative Names: Fmoc-L-glutamic acid 5-tert-butyl ester. Grades: Highly Purified. CAS No. 71989-18-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C24H27NO6. US Biological Life Sciences.
Worldwide
Fmoc-Glu(OtBu)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of glutamic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Glu(OtBu)-OH, N-α-Fmoc-L-glutamic acid γ-t.-butyl ester. Product Category: Amino Acids. CAS No. 71989-18-9. Molecular formula: C24H27NO6. Mole weight: 425.47. Product ID: ACM71989189-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-L-Glu-OtBu. Group: Biochemicals. Alternative Names: Fmoc-L-glutamic acid a-tert-butyl ester. Grades: Highly Purified. CAS No. 84793-07-7. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C24H27NO6. US Biological Life Sciences.
Worldwide
Fmoc-Gln-OH
Building block for introduction of glutamine by Fmoc SPPS. Not compatible with uronium and phosphonium coupling reagents. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Gln-OH, N-α-Fmoc-L-glutamine. Product Category: Amino Acids. CAS No. 71989-20-3. Mole weight: 368.38. Product ID: ACM71989203. Alfa Chemistry ISO 9001:2015 Certified. Categories: N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine.
Fmoc-L-glutamine
N2-Fmoc-L-glutamine is an N-Fmoc-protected form of L-Glutamine. L-Glutamine is a non-essential amino acid that is important for cells which proliferate quickly in the body, such as those of the immune system. L-Glutamine is known to be especially important for the gut, as it helps maintain intestinal structure and function. L-Glutamine also has protective properties against host toxicity of chemotherapy in cancer patients. Synonyms: Fmoc-L-glutamine; NA-FMOC-L-GLUTAMINE; FMOC-GLN; FMOC-L-GLN; L-GLUTAMINE-N-FMOC; FMOC-L-GLN-OH; Fmoc-Glutamine-OH; FMOC-GLUTAMINE; Fmoc-D-Gln-OH. Grades: ≥ 99% (HPLC, Chiral purity). CAS No. 71989-20-3. Molecular formula: C20H20N2O5. Mole weight: 368.40.
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