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Formononetin is an isoflavone found as one of the main plant estrogens in animal feed. When metabolized in the rumen this compound transforms into a potent estrogen. Group: Biochemicals. Alternative Names: 7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 7-Hydroxy-4'-methoxy- isoflavone; 7-Hydroxy-3-(4-methoxyphenyl)chromen-4-one; 7-Hydroxy-4'-methoxyisoflavone; Biochanin B; Daidzein 4'-methyl ether; Flavosil; Formonentin; Formonetin; Formononetol; Myconate; NSC 93360. Grades: Highly Purified. CAS No. 485-72-3. Pack Sizes: 1g. US Biological Life Sciences.
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Formononetin
Formononetin is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone. It displays a wide variety of biological activityes, including decreasing expression of pro-imflammatory cytokines, inducing apoptosis in prostate cancer cells, lowering systolic blood pressure and inhibiting attachment and motility of Giardia. Uses: Estrogenic; antigiardial; sialidase inhibitor. Synonyms: Formononetol, Biochanin B; Formononetol Formononetin; NSC 93360; NSC93360; NSC-93360. Grade: >98%. CAS No. 485-72-3. Molecular formula: C16H12O4. Mole weight: 268.26.
Formononetin
Formononetin is a potent FGFR2 inhibitor with an IC 50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Biochanin B; Flavosil; Formononetol. CAS No. 485-72-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0183.
Formononetin
Formononetin - Product ID: NST-10-17. Category: Flavonoids. Alternative Names: Biochanin B, Daidzein 4'-methyl ether, Flavosil, Formonentin, Formonetin, Formononetol, Myconate, Myconate HB, Mycotech, Neochanin. Purity: 98%. Test method: HPLC. CAS No. 485-72-3. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White to slightly grey powder. Molecular formula: C16H12O4. Mole weight: 268.26. Storage: +2 +8 °C.
Formononetin-b-D-glucuronide is a bioactive derivative originating from formononetin, an isoflavone occurring naturally in numerous plant species. It is used in the research of osteoporosand estrogen-related disorders. Synonyms: 3-(4-Methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl b-D-glucuronic acid; 7-Hydroxy-4-methoxyisoflavone-7-O-b-D-glucuronide; Formononetin-7-O-Glucuronide; Biochanin B-7-O-b-D-glucuronide. CAS No. 18524-03-3. Molecular formula: C22H20O10. Mole weight: 444.39.
Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones. The enzyme is involved in formononetin biosynthesis in legumes. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase). Group: Enzymes. Synonyms: SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.212. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1814; 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; EC 2.1.1.212; SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Cat No: EXWM-1814.
4'-methoxyisoflavone 2'-hydroxylase
A heme-thiolate protein (P-450). Acts on isoflavones with a 4'-methoxy group, such as formononetin and biochanin A. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. EC 1.14.13.89, isoflavone 2'-hydroxylase, is less specific and acts on other isoflavones as well as 4'-methoxyisoflavones. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Enzyme Commission Number: EC 1.14.13.53. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0860; 4'-methoxyisoflavone 2'-hydroxylase; EC 1.14.13.53; 110183-49-8; isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Cat No: EXWM-0860.
isoflavone 2'-hydroxylase
A heme-thiolate protein (P-450). Acts on daidzein, formononetin and genistein. EC 1.14.13.53, 4'-methoxyisoflavone 2'-hydroxylase, has the same reaction but is more specific as it requires a 4'-methoxyisoflavone. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Enzyme Commission Number: EC 1.14.13.89. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0897; isoflavone 2'-hydroxylase; EC 1.14.13.89; 110183-49-8; isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Cat No: EXWM-0897.
The 6-position of the glucose residue of formononetin can also act as acceptor; some other 7-O-glucosides of isoflavones, flavones and flavonols can also act, but more slowly. Group: Enzymes. Synonyms: flavone/flavonol 7-O-β-D-glucoside malonyltransferase; flavone (flavonol) 7-O-glycoside malonyltransferase; malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase; MAT-7; malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase; malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. Enzyme Commission Number: EC 2.3.1.115. CAS No. 93585-97-8, 78413-09-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2054; isoflavone-7-O-β-glucoside 6''-O-malonyltransferase; EC 2.3.1.115; 93585-97-8, 78413-09-9; flavone/flavonol 7-O-β-D-glucoside malonyltransferase; flavone (flavonol) 7-O-glycoside malonyltransferase; malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase; MAT-7; malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase; malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. Cat No: EXWM-2054.
isoflavone 7-O-glucosyltransferase
The 4'-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4'-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins. Group: Enzymes. Synonyms: uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.170. CAS No. 97089-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2395; isoflavone 7-O-glucosyltransferase; EC 2.4.1.170; 97089-62-8; uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Cat No: EXWM-2395.
Ononin
Ononin is an isoflavonoid, is an additional growth inhibitor in soils associated with the weed, Pluchea lanceolata. It may act by inducing erythropoietin expression. It can inhibit the growth of pathogen. It play an important role in human nutrition as health promoting natural chemicals and are established to be the beneficial components. Uses: Inhibit the growth of pathogen. Synonyms: Fomononetin; Formononetin 7-O-β-D-glucopyranoside; Ononoside. Grade: >98%. CAS No. 486-62-4. Molecular formula: C22H22O9. Mole weight: 430.4.
Ononin
Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Ononoside; Formononetin 7-O-β-D-glucopyranoside. CAS No. 486-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0270.
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