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FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). Group: Biochemicals. Alternative Names: 2-Amino-2- (2- (4-octylphenyl) ethyl) propane-1, 3-diol Hydrochloride; Fingolimod Hydrochloride. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 100mg. US Biological Life Sciences.
Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 50mg. US Biological Life Sciences.
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FTY720 hexanoic acid hydrochloride
FTY720 hexanoic acid hydrochloride. Group: Biochemicals. Alternative Names: 4-[3-Amino-4-hydroxy-3- (hydroxymethyl) butyl]benzenehexanoic acid hydrochloride. Grades: Highly Purified. CAS No. 896472-94-9. Pack Sizes: 10mg. Molecular Formula: C17H28ClNO4. US Biological Life Sciences.
Worldwide
FTY720 octanoic acid hydrochloride
FTY720 octanoic acid hydrochloride. Group: Biochemicals. Alternative Names: 4-[3-Amino-4-hydroxy-3- (hydroxymethyl) butyl]benzeneoctanoic acid hydrochloride. Grades: Highly Purified. CAS No. 896472-95-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C19H32ClNO4. US Biological Life Sciences.
Worldwide
Fingolimod-d4 hydrochloride
Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1.
Fingolimod-[d4] Hydrochloride
Fingolimod-[d4] Hydrochloride is the labelled salt of Fingolimod. Fingolimod is an antagonist of S1P which is an extracellular lipid mediator. Fingolimod has been used as an immunomodulating drug to treat multiple sclerosis (MS). Synonyms: Fingolimod D4 Hydrochloride; 2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol-d4 Hydrochloride; FTY720-d4 Hydrochloride. Grade: ≥99% by HPLC; 99% atom D. CAS No. 1346604-90-7. Molecular formula: C19H30D4ClNO2. Mole weight: 347.96.
Fingolimod hydrochloride
Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005.
Fingolimod hydrochloride
Fingolimod (FTY720) is a S1P antagonist with IC50 of 0.033 nM. Synonyms: Fingolimod hydrochloride; FTY720; FTY 720; FTY-720. Grade: >98%. CAS No. 162359-56-0. Molecular formula: C19H33NO2.HCl. Mole weight: 343.9.
Fingolimod hydrochloride
Fingolimod hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FTY720. Appearance: White powder. CAS No. 162359-56-0. Molecular formula: C19H34ClNO2. Mole weight: 343.93. Purity: 0.98. IUPACName: 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol;hydrochloride. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl. Product ID: ACM162359560. Alfa Chemistry ISO 9001:2015 Certified.
Fingolimod Phosphate HCl
A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grade: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46.
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