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FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). Group: Biochemicals. Alternative Names: 2-Amino-2- (2- (4-octylphenyl) ethyl) propane-1, 3-diol Hydrochloride; Fingolimod Hydrochloride. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 100mg. US Biological Life Sciences.
Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 50mg. US Biological Life Sciences.
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FTY720 hexanoic acid hydrochloride
FTY720 hexanoic acid hydrochloride. Group: Biochemicals. Alternative Names: 4-[3-Amino-4-hydroxy-3- (hydroxymethyl) butyl]benzenehexanoic acid hydrochloride. Grades: Highly Purified. CAS No. 896472-94-9. Pack Sizes: 10mg. Molecular Formula: C17H28ClNO4. US Biological Life Sciences.
Worldwide
FTY720 octanoic acid hydrochloride
FTY720 octanoic acid hydrochloride. Group: Biochemicals. Alternative Names: 4-[3-Amino-4-hydroxy-3- (hydroxymethyl) butyl]benzeneoctanoic acid hydrochloride. Grades: Highly Purified. CAS No. 896472-95-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C19H32ClNO4. US Biological Life Sciences.
Worldwide
Fingolimod-d4 hydrochloride
Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1.
Fingolimod hydrochloride
Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005.
Fingolimod hydrochloride
Fingolimod hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FTY720. Appearance: White powder. CAS No. 162359-56-0. Molecular formula: C19H34ClNO2. Mole weight: 343.93. Purity: 0.98. IUPACName: 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol;hydrochloride. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl. Product ID: ACM162359560. Alfa Chemistry ISO 9001:2015 Certified.
Fingolimod Phosphate HCl
A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grades: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46.
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