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| Product | Description | |
|---|---|---|
| FTY720 Phosphate | FTY720 is a derivative of ISP-1 (myriocin). FTY720 phosphate is a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5, IC50 values = 0.2-6 nM). Synonyms: FTY720P; 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, 1-(dihydrogen phosphate). Grades: ≥98%. CAS No. 402615-91-2. Molecular formula: C19H34NO5P. Mole weight: 387.5. |  |
| Fty720(R)-phosphate | Fty720(R)-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: fingolimod-P; FTY720-P; FTY720-phosphate,rac-2; FTY720 phosphate. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 402616-23-3. Molecular formula: C19H34NO5P. Mole weight: 387.5. Purity: ≥98%. IUPACName: [2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate. Canonical SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(COP(=O)(O)O)N. Product ID: ACM402616233. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fingolimod phosphate. |  |
| FTY720 (R)-Phosphate | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720 (R)-phosphate is one of the stereoisomers of FTY720-phosphate. Synonyms: (2R)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol. Grades: ≥98%. CAS No. 402616-23-3. Molecular formula: C19H34NO5P. Mole weight: 387.5. | |
| FTY720 (S)-Phosphate | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720 (S)-phosphate is the single stereoisomer of FTY720. FTY720 (S)-phosphate exhibits Ki values of 2.1, 5.9, 23, and 2.2 nM for S1P1,3,4,5, respectively, whereas the R enantiomer binds with 5 to 130-fold lower affinity. Synonyms: (S)-FTY 720P; (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol. Grades: ≥98%. CAS No. 402616-26-6. Molecular formula: C19H34NO5P. Mole weight: 387.5. | |
| rac FTY720 Phosphate | rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Group: Biochemicals. Alternative Names: 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate); 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester; FTY720-P; FTY-P; Fingolimod phosphate. Grades: Highly Purified. CAS No. 402615-91-2. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. |  Worldwide |
| (S)FTY720 phosphate | (S)FTY720 phosphate. Group: Biochemicals. Alternative Names: 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol mono(dihydrogen phosphate) ester; (S)-FTY720-P. Grades: Highly Purified. CAS No. 402616-26-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H34NO5P. US Biological Life Sciences. | Worldwide |
| (S) FTY720 Phosphate (2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester, (S)-FTY720-P) | A sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. It is the active metabolite of FTY720-phosphate. Group: Biochemicals. Alternative Names: 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester; (S)-FTY720-P. Grades: Highly Purified. CAS No. 402616-26-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl-methyl-d4 Phosphate | 2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl-methyl-d4 Phosphate is an intermediate in the production of labelled FTY720. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| azido-FTY720 | Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibits lymphocyte egress from lymphoid tissues by down-regulating sphingosine-1 phosphate receptor (S1PR). Phosphorylation of FTY270 by sphingosine kinase can cause S1P1R internalization, which sequesters lymphocytes in lymph nodes, preventing them from taking part in an autoimmune response. It is a first-in-class orally bioavailable compound that has shown efficacy in advanced clinical trials for the treatment of multiple sclerosis (MS). Synonyms: azido-FTY720; 881914-35-8; 2-Amino-2-[2-(3-azido-4-octylphenyl)ethyl]-1,3-propanediol; 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol; 1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]-; AKOS040755896; HY-134976; CS-0168486. Grades: ≥98%. CAS No. 881914-35-8. Molecular formula: C19H32N4O2. Mole weight: 348.5. | |
| Dibenzyl [2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl]methyl-d4 Phosphate | Dibenzyl [2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl]methyl-d4 Phosphate is an intermediate in the production of labelled FTY720. Group: Biochemicals. Alternative Names: [2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl]methyl-d4 Phosphate Dibenzyl Ester; [4,5-Dihydro-2-methyl-4-[2-(4-octylphenyl)ethyl]-4-oxazolyl]methyl-phosphoric-d4 Acid Bis(phenylmethyl) Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fingolimod | Fingolimod (FTY720 free base) is a sphingosine 1-phosphate ( S1P ) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 free base. CAS No. 162359-55-9. Pack Sizes: 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-11063. |  |
| Fingolimod-d4 | Fingolimod-d 4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720 free based-d4. CAS No. 1346747-38-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-11063S. | |
| Fingolimod-d4 hydrochloride | Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1. | |
| Fingolimod hydrochloride | Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005. | |
| Fingolimod Hydrochloride (FTY-720A, FTY720, D04187, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Hydrochloride) | Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Fingolimod phosphate | Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 phosphate. CAS No. 402615-91-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15381. | |
| Fingolimod Phosphate HCl | A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grades: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46. | |
| Fingolimod (Standard) | Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162359-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11063R. | |
| FTY720 phenoxy-biotin | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. Biotin-FTY720 is a biotin-tagged analog of FTY720. The hydroxy methyl side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained in this analog, which means that it would likewise be phosphorylated in vivo. Synonyms: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol-N-biotinoyl-1,5-diampentane. Grades: ≥95%. Molecular formula: C27H44N4O5S·HCl. Mole weight: 573.2. | |
| 2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl-methyl Phosphate | Intermediate in the production of FTY720. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246819-15-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Dibenzyl {2-Methyl-4-[2-(4-octylphenyl)ethyl]-4,5-dihydro-1,3-oxazol-4-yl}methyl Phosphate | InIntermediate in the production of FTY720. Group: Biochemicals. Alternative Names: Phosphoric Acid [4,5-Dihydro-2-methyl-4-[2-(4-octylphenyl)ethyl]-4-oxazolyl]methyl Bis(phenylmethyl) Ester. Grades: Highly Purified. CAS No. 1065472-74-3. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| FTY720 Hydrochloride (Gilenya, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol. HCl, Fingolimod) | Cell permeable immunosuppressor displaying lymphocyte sequestration properties and used for treatment in multiple sclerosis. Potent sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) agonist when phosphorylated by sphingosine kinase. Sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1 activity enhancer. Cytosolic phospholipase A2 inhibitor, independent of sphingosine 1-phosphate receptors. Autophagy inducer. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 162359-56-0. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
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