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| Product | Description | |
|---|---|---|
| 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase | This enzyme is the product of the Lewis blood group gene. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. Although it is a 4-fucosyltransferase, it has a persistent 3-fucosyltransferase activity towards the glucose residue in free lactose. This enzyme fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3, unlike EC 2.4.1.152, 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase, which fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4. Enzymes catalysing the 4-α-fucosylation of the GlcNAc in β-D-Gal-(1?3)-β-GlcNAc sequences (with some activity also as 3-α-fucosyltransferases) are present in plants, where the function in vivo is the modification of N-glycans. In addition, the fucTa gene of Helicobacter strain UA948 encodes a fucosyltransferase with both 3-α- and 4-α-fucosyltransferase activities. Group: Enzymes. Synonyms: (Lea)-dependent (α-3/4)-fucosyltransferase; α(1,3/1,4) fucosyltransferase III; α-(1?4)-L-fucosyltransferase; α-4-L-fucosyltransferase; β-acetylglucosaminylsaccharide fucosyltransferase; FucT-II; Lewis α-(1?3/4)-fucosyltransferase; Lewis blood group α-(1?3/4)-fucosyltransferase; Lewis(Le) blood . Enzyme Commi |  |
| 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase | Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3. Group: Enzymes. Synonyms: Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fu. Enzyme Commission Number: EC 2.4.1.152. CAS No. 39279-34-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2378; 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase; EC 2.4.1.152; 39279-34-0; Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fucosyltransferase; GDP-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-α-L-fucosyltransferase. Cat No: EXWM-2378. | |
| α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant | A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.65. CAS No. 37277-69-3. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter mustelae. Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Cat No: NATE-1484. | |
| α-1-3,4 Fucosyltransferase, helicobacter pylori | alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (EC 2.4.1.65) (Hp3/4FT) can be found in Helicobacter pylori. alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) catalyzes fucose transfer from donor GDP-beta-l-fucose to the GlcNAc [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-1-3,4 FucT; Hp3/4FT. CAS No. 37277-69-3. Pack Sizes: 1 U; 25 U; 5 U. Product ID: HY-E70058. |  |
| α-1,3-fucosyltransferase from Helicobacter pylori, Recombinant | A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter pylori. glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha 1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Cat No: NATE-1483. | |
| galactoside 2-α-L-fucosyltransferase | Free lactose can act as acceptor. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. The action on glycolipid was previously listed as EC 2.4.1.89. Group: Enzymes. Synonyms: blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fuco. Enzyme Commission Number: EC 2.4.1.69. CAS No. 56093-23-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2612; galactoside 2-α-L-fucosyltransferase; EC 2.4.1.69; 56093-23-3; blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fucose-lactose fucosyltransferase; guanosine diphospho-L-fucose-lactose fucosyltransferase; guanosine | |
| GDP-Fuc:β-D-Gal-1,3-α-D-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,2-fucosyltransferase | The enzyme is involved in the biosynthesis of the O-polysaccharide repeating unit of the bacterium Escherichia coli serotype O86. Group: Enzymes. Synonyms: WbnK. Enzyme Commission Number: EC 2.4.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2543; GDP-Fuc:β-D-Gal-1,3-α-D-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,2-fucosyltransferase; EC 2.4.1.308; WbnK. Cat No: EXWM-2543. | |
| glycoprotein 3-α-L-fucosyltransferase | Requires Mn2+. The enzyme transfers to N-linked oligosaccharide structures (N-glycans), generally with a specificity for N-glycans with one unsubstituted non-reducing terminal GlcNAc residue. This enzyme catalyses a reaction similar to that of EC 2.4.1.68, glycoprotein 6-α-L-fucosyltransferase, but transferring the L-fucosyl group from GDP-β-L-fucose to form an α1,3-linkage rather than an α1,6-linkage. The N-glycan products of this enzyme are present in plants, insects and some other invertebrates (e.g., Schistosoma, Haemonchus, Lymnaea). Group: Enzymes. Synonyms: GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamine (Fuc to (Fucα1?6GlcNAc)-Asn-peptide) α1?3-fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. α-fucosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2442; glycoprotein 3-α-L-fucosyltransferase; EC 2.4.1.214; 68247-53-0; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamin | |
| glycoprotein 6-α-L-fucosyltransferase | This enzyme catalyses a reaction similar to that of EC 2.4.1.214, glycoprotein 3-α-L-fucosyltransferase, but transfers the L-fucosyl group from GDP-β-L-fucose to form an α1,6-linkage rather than an α1,3-linkage. Group: Enzymes. Synonyms: GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-link. Enzyme Commission Number: EC 2.4.1.68. CAS No. 9033-8-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2611; glycoprotein 6-α-L-fucosyltransferase; EC 2.4.1.68; 9033-08-3; GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?3)-[N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?6)]-β-D-mannosyl-(1?4)-N-acetyl-β-D-glucosaminyl- | |
| peptide-O-fucosyltransferase | Involved in the biosynthesis of O-fucosylated epidermal growth factor (EGF) and thrombospondin type 1 repeats. The attachment of O-linked fucose to serine or threonine occurs on EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys. Group: Enzymes. Synonyms: GDP-L-fucose:polypeptide fucosyltransferase; GDP-fucose protein O-fucosyltransferase; GDP-fucose:polypeptide fucosyltransferase. Enzyme Commission Number: EC 2.4.1.221. CAS No. 9033-8-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2450; peptide-O-fucosyltransferase; EC 2.4.1.221; 9033-08-3; GDP-L-fucose:polypeptide fucosyltransferase; GDP-fucose protein O-fucosyltransferase; GDP-fucose:polypeptide fucosyltransferase. Cat No: EXWM-2450. | |
| 2,6-Dideoxy-2-fluoro-L-galactopyranose (α, β Mixture) | 2,6-Dideoxy-2-fluoro-L-galactopyranose (α, β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro- β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H11FO4, Molecular Weight: 166.15. US Biological Life Sciences. |  Worldwide |
| 2,6-Dideoxy-2-fluoro-L-galactopyranose (α,β Mixture) | 2,6-Dideoxy-2-fluoro-L-galactopyranose (α,β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro-β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Synonyms: 2-Deoxy-2-fluoro-L-fucose. Molecular formula: C6H11FO4. Mole weight: 166.15. |  |
| 2-Amino-2-deoxy-L-arabinose hydrochloride | 2-Amino-2-deoxy-L-arabinose hydrochloride, a pharmacological compound, has gained attention for its antitumor and immunomodulatory properties. Through its potent inhibition of fucosyltransferase (FUT), a key enzyme involved in the formation of Lewis X antigen, it shows promise as a therapeutic agent for an array of malignancies and immunological conditions. The multifaceted mechanisms by which 2-Amino-2-deoxy-L-arabinose hydrochloride exerts its effects requires further study, but the potential for groundbreaking advancements in the field of oncology and immunotherapy cannot be denied. Synonyms: (2R,3R,4S)-2-Amino-3,4,5-trihydroxypentanal hydrochloride; 65982-16-3. CAS No. 65982-16-3. Molecular formula: C5H11NO4.HCl. Mole weight: 185.61. | |
| 2-Amino-2-deoxy-L-fucose | 2-Amino-2-deoxy-L-fucose, a monosaccharide of paramount significance, intricately participates in the inherent complexity of glycan biosynthesis. Its versatile attributes serve as a substrate for fucosyltransferases, inducing the production of fucosylated glycans, a heterogeneous group of biomolecules, meticulously regulating critical biological processes, including cell adhesion and signal transduction. Researchers have also investigated its potential therapeutic applications in ameliorating cancer and inflammatory diseases. Synonyms: 2-Amino-2,6-dideoxy-L-galactose L-Fucosamine. CAS No. 7577-62-0. Molecular formula: C6H13NO4. Mole weight: 163.17. | |
| 4,6-O-Benzylidene Lactosamine 6-Sulfate Pentaacetate Triethylamine Salt | An intermediate in the preparation of α1,3-L-Fucosyltransferase acceptors. Synonyms: 2-(Acetylamino)-2-deoxy-4-O-(4,6-O-benzylidene-di-o-acetyl-β-D-galactopyranosyl)-tri-O-acetyl-D-glucose 6-(Hydrogen Sulfate) Triethylamine Salt. Molecular formula: C35H51N2O18S. Mole weight: 819.85. | |
| 4-Nitrophenyl 2-O-(2,3,4-tri-O-acetyl-b-L-fucopyranosyl)-6-O-benzoyl-a-D-galactopyranoside | 4-Nitrophenyl 2-O-(2,3,4-tri-O-acetyl-b-L-fucopyranosyl)-6-O-benzoyl-a-D-galactopyranoside is a compound used in biomedical research. It is commonly utilized as a substrate in enzymatic assays to study fucosyltransferase activity. This compound aids in the investigation of glycan biosynthesis and can be employed in the development of potential anti-cancer or anti-viral drugs targeting fucose-containing glycans. Molecular formula: C31H35NO16. Mole weight: 677.61. | |
| 4-Nitrophenyl b-D-fucopyranoside | 4-Nitrophenyl b-D-fucopyranoside is a biochemical compound widely used in the biomedical industry acting as a substrate for enzymatic assays to study the activity of fucosyltransferases. It provides valuable insights into enzyme kinetics, drug development and understanding diseases related to alterations in fucose metabolism or glycosylation patterns. Synonyms: PNP-b-D-Fuc. CAS No. 1226-39-7. Molecular formula: C12H15NO7. Mole weight: 285.25. | |
| GDP-2F-Fuc ammonium salt | A competitive inhibitor of fucosyltransferases FUT3, FUT5, FUT6 and FUT7 with Ki values in low micromolar range. This fluorinated GDP-fucose analog inhibits oligosaccharide core fucosylation of N-linked glycans in animal and plant cells. Synonyms: GDP-2-deoxy-2-fluoro-L-fucose ammonium salt. Molecular formula: C16H30FN7O14P2. Mole weight: 625.39. | |
| GDP-Gel / GDP-Agarose | GDP-Gel is the GDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of fucosyltransferases. Synonyms: Guanosine- 5'- O- diphosphate, immobilized on a polymeric matrix. | |
| GDP-L-fucose diammonium salt | GDP-L-fucose diammonium salt is an indispensable compound, serving as a vital substrate for fucosyltransferase. This compound intricately contributes to the biosynthesis of fucosylated glycans. Molecular formula: C15H23N5O15P2 N2H8. Mole weight: 623.41. | |
| GDP-L-fucose disodium salt | Substrate for fucosyltransferase. Synonyms: Guanosine 5'-pyrophosphate, β-L-fucopyranosyl ester Disodium Salt; Guanosine pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine diphosphofucose Disodium Salt; Guanosine diphosphate fucose Disodium Salt; Guanosine 5'-pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine 5'-diphospho-β-L-fucose Disodium Salt; GDP-Fucose Disodium Salt. Grades: ≥95%. CAS No. 148296-47-3. Molecular formula: C16H23N5O15P2Na2. Mole weight: 633.31. | |
| Lacto-N-biose I | Lacto-N-biose I (Galβ1-3GlcNAc), as an endogenous metabolite, is an acceptor for the α1,2-fucosyltransferase enzyme from Helicobacter pylori [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Galβ1-3GlcNAc. CAS No. 50787-09-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141488. | |
| Lacto-N-fucopentaose II-APD-KLH | Lacto-N-fucopentaose II-APD-KLH is an extraordinary bioactive compound prevalent in the biomedical sector, exhibitionizes immense promise for research across diverse diseases through its remarkable affinities for selective receptors, namely Fucosyltransferase and Galectins. It has garnered extensive utilization within research domains aiming to unravel the intricacies of cancer, inflammation and immune-related maladies, as well as devising innovative strategies for their effective research. | |
| Octyl 2-(Acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl-β-D-glucopyranoside | Octyl 2-(Acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl-β-D-glucopyranoside can be used as a substrate to elucidate the mechanism of α-1,3-fucosyltransferase. Synonyms: N-Acetyllactosamine Octyl Ester. CAS No. 178977-64-5. Molecular formula: C22H41NO11. Mole weight: 495.56. | |
| TDP-a-D-fucose ammonium salt | TDP-a-D-fucose ammonium salt, a biochemical with vast utility in the synthesis of fucosylated biomolecules, is a substrate analog with proven efficacy in measuring the activity of fucosyltransferases, central players in the biosynthesis of glycan structures found in glycoproteins and glycolipids. In addition, this product has been demonstrated to be of major significance in foundational research related to cancer, immune response, and host-pathogen interactions. Molecular formula: C16H32N4O16P2. Mole weight: 598.39. | |
| Thymidine-5'-diphosphate-b-L-fucose | Thymidine-5'-diphosphate-b-L-fucose is a pivotal compound within the realm of glycobiology research, acting as an invaluable substrate for pivotal fucosylation-related enzymes.It seamlessly facilitates extensive exploration of fucosylated compound biosynthesis, fucosyltransferase functionalities and the intricate implications surrounding pathologies associated with fucose-deficient glycoproteins. Synonyms: TDP-Fucose. | |
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