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| Product | Description | |
|---|---|---|
| Fumagillin | Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent. Group: Biochemicals. Alternative Names: Methionine aminopeptidase-2 Inhibitor; (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3- (3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8- decatetraenedioic acid ester. Grades: Highly Purified. CAS No. 23110-15-8. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C26H34O7, Molecular Weight: 458.54. US Biological Life Sciences. |  Worldwide |
| Fumagillin | Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an anti-infective and antiangiogenic agent. Synonyms: NSC-9168; Fumidil B; Fumagillin; Fumagilina; Fugillin; Fumidil. Grade: >98%. CAS No. 23110-15-8. Molecular formula: C26H34O7. Mole weight: 458.54. |  |
| Fumagillin | Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV-1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC9168; NSC 9168; NSC-9168; Fumidil B; Fumagillin, trade name: Fumagilina; Fugillin; Fumidil. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 23110-15-8. Molecular formula: C26H34O7. Mole weight: 458.55 g/mol. Purity: ≥98%. IUPACName: (2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid. Canonical SMILES: O=C(O)/C=C/C=C/C=C/C=C/C(O[C@H](CC1)[C@@H](OC)[C@H]([C@@]2(C)OC2C/C=C(C)\C)[C@]31CO3)=O. Product ID: ACM23110158. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fumagillin | Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV?1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity. Uses: Scientific research. Group: Natural products. Alternative Names: Amebacilin; NSC9168. CAS No. 23110-15-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-B0751. |  |
| Fumagillin from Aspergillus fumigatus | ?90%, powder. Group: Fluorescence/luminescence spectroscopy. |  |
| cis-Fumagillin methyl ester | Cis-Fumagillin methyl ester is originally isolated from Penicillum sp. F2757. It inhibits the MetAP2 and MetAPI with IC50 of 6.3nmol/L and <200nmol/L, respectively. Molecular formula: C27H36O7. Mole weight: 472.57. | |
| Beloranib | Beloranib is a fumagillin-class methionine aminopetidase-2 (MetAP2) inhibitor. Beloranib decreases food intake, body weight, fat mass, and the size of adipocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZGN-440; CKD-732 free base. CAS No. 251111-30-5. Pack Sizes: 1 mg. Product ID: HY-14811. | |
| Beloranib | Beloranib is an experimental drug candidate for the treatment of obesity. It was discovered by CKD Pharmaceuticals and is currently being developed by Zafgen. Beloranib, an analog of the natural chemical compound fumagillin, is an inhibitor of the enzyme METAP2. It was originally designed as angiogenesis inhibitor for the treatment of cancer. Uses: Angiogenesis inhibitors. Synonyms: 2-Propenoic acid, 3-[4-[2-(dimethylamino)ethoxy]phenyl]-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester, (2E)-; CDK-732; CDK 732; CDK732; O-[4-(2-Dimethylaminoethoxy)-trans-cinnamoyl]fumagillol; 2-Propenoic acid, 3-[4-[2-(dimethylamino)ethoxy]phenyl]-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester, (2E)-; ZGN 440. Grade: ≥95%. CAS No. 251111-30-5. Molecular formula: C29H41NO6. Mole weight: 499.64. | |
| Beloranib Hemioxalate | Beloranib Hemioxalate is the acidic form of beloranib , which is an analog of the natural chemical compound fumagillin and is an experimental injectable drug candidate for the treatment of obesity. Synonyms: CKD 732; (2E)-(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl Ester 3-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-propenoic Acid Ethanedioate (2:1). Grade: > 95%. CAS No. 529511-79-3. Molecular formula: C30H42NO8. Mole weight: 544.67. | |
| Fumagillol | Fumagillol is an analog of Fumagillin (F862650), a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent. Group: Biochemicals. Alternative Names: (3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]octan-6-ol; (3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]octan-6-ol; [3R-[3α, 4α(2R*, 3R*), 5 β,6 β]]-5-Methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]octan-6-ol; (-)-Fumagillol; FOS 37. Grades: Highly Purified. CAS No. 108102-51-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C??H??O?, Molecular Weight: 282.38. US Biological Life Sciences. | Worldwide |
| Fumagillol | Fumagillol is a precursor of Fumagillin, which is an antimicrobial agent used for the treatment of microsporidiosis. Fumagillol also exhibits anti-infective and antiangiogenic effects. Synonyms: 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-; (3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]octan-6-ol; 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, (3R,4S,5S,6R)-; 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, [3R-[3α,4α(2R*,3R*),5β,6β]]-; (-)-Fumagillol; FOS 37; Gelcohol. Grade: 90%. CAS No. 108102-51-8. Molecular formula: C16H26O4. Mole weight: 282.38. | |
| TNP-470 (AGM-1470, O-(Chloroacetyl-carbamoyl)fumagillol, AGM1470, MetAP-2 Inhibitor II, MetAP2 Inhibitor II, Methionine Aminopeptidase 2 Inhibitor II, TNP470) | A cell-permeable Fumagillin analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity (IC50 = 1nM against human MetAP2), without affecting the inhibitory activity of MetAP2 against HRI- (heme-regulated inhibitor kinase) catalyzed eIF-2alpha phosphorylation. A potent endothelial cytostasis inducer (IC50 = 25 pM and 37 pM, respectively, against HUVEC and bovine BAEC) in vitro and an effective anti-angiogenesis agent in vivo (2-100mg/kg in mice and rats; s.c.). Group: Biochemicals. Grades: Highly Purified. CAS No. 129298-91-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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