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Fumitremorgin c Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12α-Fumitremorgin C. Product Category: Inhibitors. Appearance: Solid. CAS No. 118974-02-0. Molecular formula: C22H25N3O3. Mole weight: 379.5. Purity: 95%+. Canonical SMILES: O=C([C@]1([H])CC2=C([C@H](/C=C(C)\C)N13)NC4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O. Product ID: ACM118974020. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Fumitremorgin C from Neosartorya fischeri, film. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Fumitremorgin C Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: 12α-Fumitremorgin C. CAS No. 118974-02-0. Pack Sizes: 10 mM * 1 mL; 250 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2143. MedChemExpress MCE
Fumitremorgin C Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 118974-02-0. Pack Sizes: 250ug. US Biological Life Sciences. USBiological 1
Worldwide
Fumitremorgin C Fumitremorgin C, isolated from Aspergillus fumigatus, is a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Synonyms: tryproquivaline D (2'S-(2'alpha,9'alpha(4R*(S*)),9'abeta))-isomer; tryproquivaline L (9'R-(9'alpha(R*),9'abeta))-isomer; tryproquivaline M (2'S-(2'alpha,9'alpha(4R*(S*)),9'abeta))-isomer; tryproquivaline N (2'S-(2'alpha,9'alpha(R*),9'abeta))-isomer; tryptoquivaline; (5aS, 12S, 14aS)-1, 2, 3, 5a, 6, 11, 12, 14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H, 14H-pyrrolo[1'', 2'':4', 5']pyrazino[1', 2':1, 6]pyrido[3, 4-b]indole-5, 14-dione. Grades: ≥95%. CAS No. 118974-02-0. Molecular formula: C22H25N3O3. Mole weight: 379.45. BOC Sciences 5
fumitremorgin C monooxygenase A heme-thiolate protein (P-450). Involved in the biosynthetic pathway of the indole alkaloid verruculogen. Group: Enzymes. Synonyms: ftmG (gene name). Enzyme Commission Number: EC 1.14.13.177. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0775; fumitremorgin C monooxygenase; EC 1.14.13.177; ftmG (gene name). Cat No: EXWM-0775. Creative Enzymes
fumitremorgin C synthase A heme-thiolate protein (P-450). The protein from the fungus Aspergillus fumigatus also has activity with tryprostatin B forming demethoxyfumitremorgin C. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmE (gene name). Enzyme Commission Number: EC 1.14.21.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1021; fumitremorgin C synthase; EC 1.14.21.10; ftmE (gene name). Cat No: EXWM-1021. Creative Enzymes
Fumitremorgin C (Tryptoquivaline) Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 118974-02-0. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. USBiological 4
Worldwide
12α,13α-dihydroxyfumitremorgin C prenyltransferase The enzyme from the fungus Aspergillus fumigatus also shows some activity with fumitremorgin C. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmH (gene name); FtmPT2. Enzyme Commission Number: EC 2.5.1.110. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2726; 12α,13α-dihydroxyfumitremorgin C prenyltransferase; EC 2.5.1.110; ftmH (gene name); FtmPT2. Cat No: EXWM-2726. Creative Enzymes
6-hydroxytryprostatin B O-methyltransferase Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmD (gene name). Enzyme Commission Number: EC 2.1.1.293. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1900; 6-hydroxytryprostatin B O-methyltransferase; EC 2.1.1.293; ftmD (gene name). Cat No: EXWM-1900. Creative Enzymes
Emtricitabine Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SM-Q;4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone;(-)-BETA-2,3-DIDEOXY-5-FLUORO-3-THIACYTIDINE;EMTRICITABINE;EMTRITABINE;FTC;FUMITREMORGIN C;EMTRICITABIN. Product Category: Inhibitors. CAS No. 143491-57-0. Molecular formula: C8H10FN3O3S. Mole weight: 247.25. Purity: 0.9994. Product ID: ACM143491570. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Fumitremorgin B Fumitremorgin B is a natural compound isolated from the fermentation broth of Aspergillus fumigatus LN-4. Fumitremorgin B is a tremorgenic mycotoxin that is active against the phytopathogenic fungi. It has antifeedant activity against armyworm (M. separata) larvae when applied to fresh wheat leaves. Synonyms: Lanosulin; 5H, 14H-Pyrrolo(1'', 2'':4', 5')pyrazino(1', 2':1, 6)pyrido(3, 4-b)indole-5, 14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR-(5a-alpha,6-alpha,12-beta,14a-alpha))-. Grades: 98.5%. CAS No. 12626-17-4. Molecular formula: C27H33N3O5. Mole weight: 479.57. BOC Sciences
tryprostatin B 6-hydroxylase A heme-thiolate protein (P-450). Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmC (gene name). Enzyme Commission Number: EC 1.14.13.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0774; tryprostatin B 6-hydroxylase; EC 1.14.13.176; ftmC (gene name). Cat No: EXWM-0774. Creative Enzymes
tryprostatin B synthase The enzyme from the fungus Aspergillus fumigatus can also prenylate other tryptophan-containing cyclic dipeptides. Prenylation occurs mainly at C-2, but also at C-3. Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, cyclotryprostatins, spirotryprostatins, fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmPT1 (gene name); brevianamide F prenyltransferase (ambiguous). Enzyme Commission Number: EC 2.5.1.106. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2722; tryprostatin B synthase; EC 2.5.1.106; ftmPT1 (gene name); brevianamide F prenyltransferase (ambiguous). Cat No: EXWM-2722. Creative Enzymes
Verruculogen (NA 209A, TR 1) Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat. Group: Biochemicals. Alternative Names: (5R, 10S, 10aR) -1, 10, 10a, 14, 14aS, 15bS-hexahydro-10, 10a-dihydroxy-7-methoxy-2, 2-dimethyl-5- (2-methyl-1-propen-1-yl) -5H, 12H-3, 4-dioxa-5a, 11a, 15a-triazacyclooct [lm]indeno [5, 6-b]fluorene-11, 15 (2H, 13H) -dione. Grades: Highly Purified. CAS No. 12771-72-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H33N3O7. US Biological Life Sciences. USBiological 4
Worldwide
verruculogen prenyltransferase Found in a number of fungi. Catalyses the last step in the biosynthetic pathway of the indole alkaloid fumitremorgin A. The enzyme from the fungus Neosartorya fischeri is also active with fumitremorgin B and 12α,13α-dihydroxyfumitremorgin C. Group: Enzymes. Synonyms: FtmPT3. Enzyme Commission Number: EC 2.5.1.107. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2723; verruculogen prenyltransferase; EC 2.5.1.107; FtmPT3. Cat No: EXWM-2723. Creative Enzymes
verruculogen synthase Requires Fe2+ and ascorbate. Found in the fungus Aspergillus fumigatus. Both atoms of a dioxygen molecule are incorporated into verruculogen. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A. Group: Enzymes. Synonyms: fmtF (gene name); FmtOx1. Enzyme Commission Number: EC 1.14.11.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0656; verruculogen synthase; EC 1.14.11.38; fmtF (gene name); FmtOx1. Cat No: EXWM-0656. Creative Enzymes

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