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| Product | Description | |
|---|---|---|
| furin | One of a group of peptidases in peptidase family S8 (subtilisin family) that is structurally and functionally similar to kexin. All are activated by Ca2+, contain Cys near the active site His, and are inhibited by p-mercuribenzoate. At least three related enzymes are recognized in mammals: PC2, PC3 and PC4, which have somewhat different specificities. Group: Enzymes. Synonyms: prohormone convertase; dibasic processing enzyme; PACE; paired basic amino acid cleaving enzyme; paired basic amino acid converting enzyme; serine proteinase PACE; PC1; SPC3; proprotein convertase. Enzyme Commission Number: EC 3.4.21.75. CAS No. 141760-45-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4167; furin; EC 3.4.21.75; 141760-45-4; prohormone convertase; dibasic processing enzyme; PACE; paired basic amino acid cleaving enzyme; paired basic amino acid converting enzyme; serine proteinase PACE; PC1; SPC3; proprotein convertase. Cat No: EXWM-4167. |  |
| Furin from Human, Recombinant | Furin is a dibasic endoprotease that is localized in the Golgi apparatus. It is responsible for the proteolytic maturation of many precursor proteins in the secretory and endocytic pathways of mammalian cells. Furin is a dibasic endoprotease that is localized in the Golgi apparatus. It has a molecular mass of 52.7 kDa. It is responsible for the proteolytic maturation of many precursor proteins in the secretory and endocytic pathways of mammalian cells. Furin cleaves precursor proteins at their paired basic amino acid processing sites. Some substrates of furin include von Willebrand factor, transforming growth factor beta 1 precursor, pro-beta-secretase and proparathyroid hormo...terial exotoxins, typically at sites marked by the consensus sequence arg-xaa-(lys/arg)-arg. Group: Enzymes. Synonyms: furin; prohormone convertase; dibasic processing enzyme; PACE; paired basic amino acid cleaving enzyme; paired basic amino acid converting enzyme; serine proteinase PACE; PC1; SPC3; proprotein convertase. Furin. Activity: > 2,000 unit/mL. Storage: -70°C. Form: buffered aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. furin; prohormone convertase; dibasic processing enzyme; PACE; paired basic amino acid cleaving enzyme; paired basic amino acid converting enzyme; serine proteinase PACE; PC1; SPC3; proprotein convertase. Cat No: NATE-0268. | |
| Furin Substrate, Fluorogenic | A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 10? s?¹M?¹). Group: Fluorescence/luminescence spectroscopy. |  |
| Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | The inhibitor Decanoyl-Arg-Val-Arg-Lys-chloromethylketone has been used to characterize the specificity of furin-like proteases. Synonyms: L-Argininamide, N2-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-. CAS No. 534615-50-4. Molecular formula: C34H66ClN11O5. Mole weight: 744.41. |  |
| Hexa-D-arginine | An inhibitor of furin. Furin is a ubiquitous subtilisin-like proprotein convertase. Synonyms: Furin Inhibitor II; H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide. Grades: 98%. CAS No. 673202-67-0. Molecular formula: C36H75N25O6. Mole weight: 954.14. | |
| Hexa-D-arginine (D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2) | Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2um for furin, PACE4 and PC1 respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 673202-67-0. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Histatin-3 TFA | Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant K i of 1.98 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 112844-49-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5272. |  |
| L-Aspartic acid,N-[N-[N-[N-[N-[N2-[N2-[N-[N2-(2-aminobenzoyl)-L-arginyl]-L-valyl]-L-lysyl]-L-arginyl]glycyl]-L-leucyl]-L-alanyl]-3-nitro-L-tyrosyl]-(9CI) | Synonyms: ABZ-ARG-VAL-LYS-ARG-GLY-LEU-ALA-M-NITRO-TYR-ASP-OH; Furin Substrate. CAS No. 174838-79-0. Molecular formula: C54H84N18O16. Mole weight: 1241.36. | |
| Naphthofluorescein | Naphthofluorescein is a furin inhibitor that inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase (MT1-MMP), resulting in decreased levels of active MT1-MMP. Naphthofluorescein is a red-emitting fluorescent probe for hydrogen peroxide in living cells. Synonyms: CCG 8295. Grades: ≥98%. CAS No. 61419-02-1. Molecular formula: C28H16O5. Mole weight: 432.4. | |
| Nitrofurantoin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standardspharmaceutical toxicology. Alternative Names: FuaMed, Furobactina, Furantoin, Furachel, Furalan, NSC 44150, Urofurin, Welfurin, 1-(5-Nitro-2-furfurylidenamino)hydantoin, Fur-ren, Nifurantin, Uro-Tablinen, Chemiofuran, 5-Nitrofurantoin, Urizept, Zoofurin, Cyantin, Furantoina,Nitrofurantoin, Furadonin, N-(5-Nitro-2-furfurylidene)-1-aminohydantoin, Urolong, Trantoin, NSC 2107, Furadonine, N-(5-Nitro-2-furfurylidine)-1-aminohydantoin, Furadantin, Cystit, Macrobid, Urodin, Orafuran, Parfuran, 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione, 1-(5-Nitro-2-furfurylideneamino)hydantoin, Furadantine MC, N-(5-Nitrofurfurylidene)-1-aminohydantoin, Furophen T-Caps, Urantoin, Ituran, Furadoin, Furina, 1-[(5-Nitrofurfurylidene)amino]hydantoin, Berkfurin, Furadantoin, Furadoine, Furatoin, Nitoin, Novofuran, Furadontin, Macrodantin. | |
| SSM 3 trifluoroacetate | SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM) which blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro. Synonyms: SSM 3 trifluoroacetate; SSM3 trifluoroacetate; SSM-3 trifluoroacetate; SSM3 TFA; SSM-3 TFA; SSM 3 TFA; SSM3 TFA salt; rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt. Grades: ≥98% by HPLC. CAS No. 922732-52-3. Molecular formula: C22H32N12O2.4CF3CO2H. Mole weight: 952.66. | |
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