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Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation. Uses: Scientific research. Group: Signaling pathways. CAS No. 85305-88-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151240.
galactosylceramide sulfotransferase
Also acts on lactosylceramide. Group: Enzymes. Synonyms: GSase; 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase. Enzyme Commission Number: EC 2.8.2.11. CAS No. 9081-6-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3370; galactosylceramide sulfotransferase; EC 2.8.2.11; 9081-06-5; GSase; 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase. Cat No: EXWM-3370.
α-Galactosylceramide
α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-GalCer; KRN7000. CAS No. 158021-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-102022.
b-D-Galactosylceramide
b-Galactosylceramides - from bovine brain
Cas No. 85305-88-0.
C2 Adamantanyl Galactosylceramide (d18:1/2:0)
C2 Adamantanyl Galactosylceramide (d18:1/2:0) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. Synonyms: [(2S,3R,4E)-2-[(1-Adamantyl)acetylamino]-3-hydroxy-4-octadecenyl]beta-D-galactopyranoside; N-(1-Adamantaneacetyl)-galactosylceramide; Adamantanyl Galactosyl(β) Ceramide; AdaGalCer(d18:1/2:0). Grades: ≥98%. CAS No. 574738-16-2. Molecular formula: C36H63NO8. Mole weight: 637.89.
GALC, Positive Control (Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase)
GALC, Positive Control (Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences.
2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thio-(α/ β)-D-galactopyranoside. (mixture of α/ β)
2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thio-(α/ β)-D-galactopyranoside is sed in the synthesis and evaluation for iNKT stimulation of α-S-galactosylceramide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C16H22O10S. US Biological Life Sciences.
Worldwide
7DW8-5
7DW8-5 (4-Fluorophenylundecanoyl-α -galactosylceramide) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Fluorophenyl undecanoyl -α-galactosyl ceramide. CAS No. 1056025-00-3. Pack Sizes: 500 μg. Product ID: HY-166293.
7DW8-5
7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Studies have shown that the adjuvant effect of 7DW8-5 wasmediated by CD1dmolecules. Synonyms: [(2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-(11-(4-fluorophenyl)undecanoyl)-2-amino-1,3,4-octadecanetriol)]; N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]-11-(4-fluorophenyl)undecanamide; 11-(4-Fluorophenyl)-N-[(2s,3s,4r)-1-(Alpha-D-Galactopyranosyloxy)-3,4-Dihydroxyoctadecan-2-Yl]undecanamide; CHEBI:86489; 7DW8-5; 7DW. CAS No. 1056025-00-3. Molecular formula: C41H72FNO9. Mole weight: 742.
a-D-Galactose-1-phosphate dipotassium salt hydrate
a-D-Galactose-1-phosphate dipotassium salt hydrate is a pivotal compound in compound, emerging as an indispensable player in the intricate realm of galactosylceramide bioresearch and development. Synonyms: a-D-Galactose-1-phosphate dipotassium salt dihydrate. CAS No. 19046-60-7. Molecular formula: C6H11K2O9P.xH2O. Mole weight: 336.32 (anydrous basis).
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
a-Galactosyl-C16-ceramide (GalCer)
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Alternative Names: GalCer. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
a-Galactosyl-C18-ceramide
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
a-Galactosyl-erythro-sphingosine
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
α-Galactosyl-C18-ceramide
Galactosylceramides play a significant role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have critical immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: N-[(1S,2R,3E)-1-[(α-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]octadecanamide. Grades: 97%. CAS No. 148347-40-4. Molecular formula: C42H81NO8. Mole weight: 728.09.
β-Galactosyl-C18-ceramide
Galactosylceramides play a significant role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have critical immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: C18-Cerebroside; D-galactosyl-β-1,1'-N-stearoyl-D-erythro-sphingosine. Grades: >99%. CAS No. 36271-49-5. Molecular formula: C42H81NO8. Mole weight: 728.09.
β-Galactosyl-C18-ceramide Tetraacetate
β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the β-Galactosyl-C18-ceramide synthesis, which is a galactosylceramides involved in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have important immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-3-hydroxy-2-stearamidooctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C50H89NO12. Mole weight: 896.24.
C16 Galactosyl(α) Ceramide (d18:1/16:0)
It is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid. Synonyms: D-galactosyl-α-1,1'-N-palmitoyl-D-erythro-sphingosine; Hexadecanamide, N-[(1S,2R,3E)-1-[(α-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-; α C16 Galactosylceramide (d18:1/16:0); C16 α-D-galactosyl ceramide; N-(hexadecanoyl)-1-α-galactosyl-sphing-4-enine; N-((2S,3R,E)-3-hydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)palmitamide; N-[(2S,3R,4E)-1-(α-D-Galactopyranosyloxy)-3-hydroxy-4-octadecen-2-yl]hexadecanamide; α-GalCer(d18:1/16:0). Grades: >99%. CAS No. 2260795-77-3. Molecular formula: C40H77NO8. Mole weight: 700.04.
C24:1 Mono-sulfo galactosyl (alpha) ceramide (d18:1/24:1) Ammonium salt
C24:1 Mono-sulfo galactosyl (alpha) ceramide (d18:1/24:1) Ammonium salt is a valuable compound serving as a formidable biomarker facilitating the comprehensive investigation of ceramide involvement in diverse pathological conditions, spanning from malignancies such as cancer, to metabolic disorders like diabetes is and even neurodegenerative ailments. Synonyms: 3-O-Sulfo-D-galactosyl-alpha-1,1'-N-Nervonoyl-D-erythro-sphingsoine (ammonium salt); 3-O-sulfo-alpha-D-C24:1-galactosylceramide (ammonium salt); ammonium (2S,3R,4S,5S,6R)-3,5-dihydroxy-2-(((2S,3R,E)-3-hydroxy-2-((Z)-tetracos-15-enamido)octadec-4-en-1-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl sulfate; Ammonium (2S,3R,4E)-3-hydroxy-2-[(15Z)-15-tetracosenoylamino]-4-octadecen-1-yl 3-O-sulfonato-α-D-threo-hexopyranoside. Grades: >99%. CAS No. 2260670-38-8. Molecular formula: C48H94N2O11S. Mole weight: 907.33.
Cerebroside sulfate
Cerebroside sulfate is a remarkable biomedical compound, exhibiting prodigious potential for studying diverse neurological disorders such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. Its distinctive configuration and inherent characteristics render it an alluring contender for novel drug development aiming at the central nervous system. Encouraging outcomes from preclinical investigations substantiate its capacity to transform the research landscape of these incapacitating illnesses. Synonyms: Sulfatides; Ceramide-galactoside-3-sulfate; 3-O-sulfo-b-D-C24-galactosylceramide. CAS No. 85496-63-5. Molecular formula: C42H80NNaO11S. Mole weight: 830.14.
Destearaldehyde β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide, which is a galactosylceramide that promote the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have critical immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-2-amino-3-hydroxyoctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C32H55NO11. Mole weight: 629.78.
Destearaldehyde-N-tert-butyloxycarbonyl β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide, which is a galactosylceramide that plays an important role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-2-((tert-butoxycarbonyl)amino)-3-hydroxyoctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C37H63NO1313. Mole weight: 729.9.
Destearaldehyde-O-tert-butyldimethylsilyl-N-tert-butyloxycarbonyl β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide, which is a galactosylceramide that plays an important role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-2-((tert-butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)octadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C43H77NO13Si. Mole weight: 844.16.
galactosylceramidase
cf. EC 3.2.1.62 glycosylceramidase. Group: Enzymes. Synonyms: cerebroside galactosidase; galactocerebroside.β-galactosidase; galactosylcerebrosidase; galactocerebrosidase; ceramide galactosidase; galactocerebroside galactosidase; galactosylceramide.β-galactosidase; cerebroside β-galactosidase; galactosylceramidase I; β-galactosylceramidase; galactocerebroside-β-D-galactosidase; lactosylceramidase I; β-galactocerebrosidase; lactosylceramidase. Enzyme Commission Number: EC 3.2.1.46. CAS No. 9027-89-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3909; galactosylceramidase; EC 3.2.1.46; 9027-89-8; cerebroside galactosidase; galactocerebroside.β-galactosidase; galactosylcerebrosidase; galactocerebrosidase; ceramide galactosidase; galactocerebroside galactosidase; galactosylceramide.β-galactosidase; cerebroside β-galactosidase; galactosylceramidase I; β-galactosylceramidase; galactocerebroside-β-D-galactosidase; lactosylceramidase I; β-galactocerebrosidase; lactosylceramidase. Cat No: EXWM-3909.
KBC-007
KBC-007 is an analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse at 0.5 ng/ml, and indices IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at 8 ng/ml. Synonyms: 8-(Diheptylamino)-N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]octanamide. Grades: ≥95%. CAS No. 1037297-61-2. Molecular formula: C46H92N2O9. Mole weight: 817.23.
KRN7000
KRN7000 is a synthetic analog of α-galactosylceramide and the marine natural product agelasphin. It is a specific ligand for human and mouse NKT cells and remains the best studied ligand of the lipid-binding MHC class I-like protein CD1d. It protects against LPS-induced shock and displays potent antitumor activity in various in vivo models. Synonyms: a-Gal-Cer N-[(1S,2S,3R)-1-[(a-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide KRN7000. Grades: >99%. CAS No. 158021-47-7. Molecular formula: C50H99NO9. Mole weight: 858.32.
glycosylceramidase
Broad specificity [cf. EC 3.2.1.45 (glucosylceramidase) and EC 3.2.1.46 (galactosylceramidase)]. Also hydrolyses phlorizin to phloretin and glucose. The intestinal enzyme is a complex that also catalyses the reaction of EC 3.2.1.108 lactase. Group: Enzymes. Synonyms: phlorizin hydrolase; phloretin-glucosidase; glycosyl ceramide glycosylhydrolase; cerebrosidase; phloridzin β-glucosidase; lactase-phlorizin hydrolase; phloridzin glucosidase. Enzyme Commission Number: EC 3.2.1.62. CAS No. 9033-10-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3926; glycosylceramidase; EC 3.2.1.62; 9033-10-7; phlorizin hydrolase; phloretin-glucosidase; glycosyl ceramide glycosylhydrolase; cerebrosidase; phloridzin β-glucosidase; lactase-phlorizin hydrolase; phloridzin glucosidase. Cat No: EXWM-3926.
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