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| Product | Description | |
|---|---|---|
| Gambogic acid | Gambogic acid is a natural product inhibitor of Hsp90. Synonyms: B-Guttiferrin; Beta-Guttiferrin; Beta-Guttilactone; Cambogic acid; Guttatic acid; Guttic acid. Grades: >95%. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.76. |  |
| Gambogic Acid | Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: β-Guttilactone. Product Category: Inhibitors. Appearance: Yellow powder. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.75. Purity: 0.98. IUPACName: (Z)-4-[(1S,2S,8R,17S,19R)-12-hydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11,15-pentaen-19-yl]-2-methylbut-2-enoic acid. Canonical SMILES: CC(=CCC[C@@]1(C=CC2=C(C3=C(C(=C2O1)CC=C(C)C)O[C@@]45[C@H]6C[C@@H](C=C4C3=O)C(=O)[C@@]5(OC6(C)C)C/C=C(/C)\C(=O)O)O)C)C. Density: 1.11 g/ml. Product ID: ACM2752650. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gambogic Acid | Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-X L , Bcl-2 , Bcl-W , Bcl-B , Bfl-1 and Mcl-1 with IC 50 s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Beta-Guttiferrin. CAS No. 2752-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0087. |  |
| Gambogic Acid | Gambogic Acid is an apoptosis inducer in sever tumor cell lines via regulation of Bax and inhibition of Bcl-2 genes. Induces EGFR degredation through AMPK dependant-LRIG1 upregulation in glioma cells. Apoptosis inducer in several tumor cell lines including T47D cells. Activates caspases (EC50 values are 0.78 - 1.64uM) and competitively inhibits antiapoptotic Bcl-2 family proteins (IC50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79uM for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). Reverses gefitinib-resistance in mice bearing tumors with EGFR-T790M mutation. Also blocks Kir2.1 channels (EC50 ≤100nM). Group: Biochemicals. Alternative Names: (2Z)-2-Methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-2-butenoic acid. Grades: Purified. CAS No. 2752-65-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C38H44O8, Molecular Weight: 628.75. US Biological Life Sciences. |  Worldwide |
| Gambogic Acid Liposome | Gambogic acid (GA) is derived from the gamboge and is a protease activator and apoptosis inducer. This product is a pre-formulated liposome encapsulating Gambogic Acid. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Retinoic Acid-Gambogic Acid Liposome | Retinoic acid is an intermediate product of vitamin A metabolism. Gambogic acid is derived from the gamboge and is a protease activator and apoptosis inducer. This product is a pre-formulated composite liposome with retinoic acid and gambogic acid. It can induce apoptosis in tumor cells and exerts synergistic anti-tumor effects. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Aminochloropentenedioic acid | It is produced by the strain of Streptomyces viridogenes MA5450. It has the activity of resisting gambogic micrococcus. Synonyms: [R-(Z)]-4-Amino-3-chloro-2-pentenedioic acid; 3-Acpa; 2-Amino-3-chloro-3-pentenedioic; 4-Amino-3-chloro-2-pentenedioic acid; 2-Pentenedioic acid, 4-amino-3-chloro-, (R-(Z))-. CAS No. 90288-29-2. Molecular formula: C5H6ClNO4. Mole weight: 179.56. | |
| Gambogenic acid | Gambogenic Acid is a natural compound isolated from Garcinia hanburyi Hook. f. It shows anticancer activity. Grades: 98%. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.8. | |
| Gambogenic Acid | Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2Z)-4-[(1R,3aS,5S,12aS)-9-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-2-methyl-2-butenoic acid. Product Category: Inhibitors. Appearance: Brownish red powder. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.77. Purity: 0.98. IUPACName: (Z)-4-[(1S,2S,13S,15R)-7-[(2E)-3,7-dimethylocta-2,6-dienyl]-6,8-dihydroxy-17,17-dimethyl-5-(3-methylbut-2-enyl)-10,14-dioxo-3,16-dioxapentacyclo[11.4.1.02,11.02,15.04,9]octadeca-4,6,8,11-tetraen-15-yl]-2-methylbut-2-enoic acid. Canonical SMILES: CC(=CCC/C(=C/CC1=C(C(=C2C(=C1O)C(=O)C3=C[C@@H]4C[C@@H]5[C@@]3(O2)[C@](C4=O)(OC5(C)C)C/C=C(/C)\C(=O)O)CC=C(C)C)O)/C)C. Density: 1.27±0.1 g/ml. Product ID: ACM173932757. Alfa Chemistry ISO 9001:2015 Certified. | |
| Morellic acid | Morellic acid. Group: Biochemicals. Alternative Names: Gambogoic acid B. Grades: Plant Grade. CAS No. 5304-71-2. Pack Sizes: 10mg. Molecular Formula: C33H36O8, Molecular Weight: 560.634. US Biological Life Sciences. | Worldwide |
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