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| Product | Description | |
|---|---|---|
| Ganglioside GM2 | Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127663-77-8. Pack Sizes: 1 mg. Product ID: HY-148385. |  |
| GM2-Ganglioside | GM2-Ganglioside, a lipid molecule nestled in cellular membranes, has been linked to various pathologies of the central nervous system like Huntington's and Parkinson's disease. By delving into the underlying pathogenesis pathways, GM2-Ganglioside can serve as a potent therapeutic agent. As a clinical ingredient for vaccines against infectious diseases and a potential player in cancer therapy, this nano-molecule is showing promise as a versatile therapeutic option. Synonyms: Monosialoganglioside GM2; b-GalNAc-(1→4)-[a-Neu5Ac-(2→3)]-b-Gal(1→4)-b-Glc-(1→1)-Cer; Ganglioside GM2; Ganglioside A1; Ganglioside G5; Ganglioside GM2; Ganglioside GO; Ganglioside M2; GM2; Sialosylganglio-N-triaosylceramide; Tay-Sachs ganglioside. CAS No. 19600-01-2. |  |
| β-1,3-galactosyltransferase from Campylobacter jejuni, Recombinant | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. Group: Enzymes. Synonyms: UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase; UDP-galactose-GM2 galactosyltransferase; uridine diphosphogalactose-GM2 galactosyltransferase; GM1-synthase; ganglio. Enzyme Commission Number: EC 2.4.1.62. CAS No. 37217-28-0. Purity: min 95% by SDS-PAGE. Galactosyltransferase. Source: E. coli. Species: Campylobacter jejuni. UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase; UDP-galactose-GM2 galactosyltransferase; uridine diphosphogalactose-GM2 galactosyltransferase; GM1-synthase; ganglioside galactosyltransferase; EC 2.4.1.62; β-1,3-galactosyltransferase; CgtB. Cat No: NATE-1488. |  |
| GA2-Ganglioside | GA2-Ganglioside, a glycolipid situated on the cell surface, performs a crucial action by boosting communication between neighboring nerve cells in the nervous system. Its medicinal potency in treating diverse neurological illnesses, including Parkinson's and Alzheimer's, has been researched extensively. Furthermore, it seems GA2-Ganglioside promotes the functionality and longevity of dopaminergic neurons, making it a highly sought-after therapy for Parkinson's. Synonyms: Asialoganglioside-GM2; Gangliotriosyl ceramide; GgOse3Cer; b-GalNAc-(1→4)-b-Gal-(1→4)-b-Glc-(1→1)-Cer; Ceramide, 1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-; 1-O-[O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Asialo Gm2; Asialoganglioside GM2; Cg3Cer; Ganglio-N-triaosylceramide; Ganglioside A2; Ganglioside GA2; Ganglioside Gg3; Gangliotriaosylceramide; Gangliotriosylceramide; Gg3Cer; Glycolipid GA2; Glycosphingolipid GA2; Tay-Sachs globoside. CAS No. 35960-33-9. Molecular formula: C56H104N2O18. Mole weight: 1093.43. | |
| ganglioside galactosyltransferase | The substrate is also known as gangloside GM2, the product as gangloside GM1a. Group: Enzymes. Synonyms: UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.62. CAS No. 37217-28-0. Galactosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2605; ganglioside galactosyltransferase; EC 2.4.1.62; 37217-28-0; UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase; UDP-galactose-GM2 galactosyltransferase; uridine diphosphogalactose-GM2 galactosyltransferase; uridine diphosphate D-galactose:glycolipid galactosyltransferase; UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase; UDP-galactose-GM2 ganglioside galactosyltransferase; GM1-synthase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine β-1,3-D-galactosyltransferase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-(1?4)-β-D-glucosyl-N-acylsphingosine 3-β-D-galactosyltransferase. Cat No: EXWM-2605. | |
| Gangliotetraose | Gangliotetraose, a biomedicine product, stands as a pivotal remedy for ganglioside deficiency ailments, such as GM2-gangliosidosis and Tay-Sachs disease. Through emulating the constituents of gangliosides found naturally, it rejuvenates their abundance and ameliorates neuronal activity. Luringly, the tantalizing prospect of neuroprotection accompanies Gangliotetraose, holding great promise in its remedial capacity for those afflicted by these incapacitating disorders. Synonyms: Asialo-GM1-tetrasaccharide; Asialo GM1 oligosaccharide; O-β-D-Galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 75645-24-8. Molecular formula: C26H45NO21. Mole weight: 707.64. | |
| Gangliotriose | Gangliotriose is a crucial component utilized in the biomedical industry for researching various neurodegenerative diseases. Its structural similarities to gangliosides make it an ideal tool for studying drug targets associated with Alzheimer's disease, Parkinson's disease and other neurological disorders. Synonyms: Asialo-GM2-trisaccharide; N-Acetylgalactosamine b1-4 Lactose; Asialo GM2 oligosaccharide; GalNAc(b1-4)Gal(b1-4)Glc. CAS No. 1355005-58-1. Molecular formula: C20H35NO16. Mole weight: 545.49. | |
| GD2-GANGLIOSIDE | GD2-GANGLIOSIDE. Uses: Designed for use in research and industrial production. Appearance: Film (dried in situ). CAS No. 65988-71-8. Molecular formula: C74H134N4O32. Mole weight: 1591.86. Purity: 0.95. Product ID: ACM65988718. Alfa Chemistry ISO 9001:2015 Certified. Categories: GM2 (ganglioside). |  |
| GM2-Oligosaccharide | GM2-Oligosaccharide is a prominent constituent in the realm of biomedical applications, finding extensive utility in the investigation of lysosomal storage disorders. Acting as an invaluable compound in the scientific domain, this oligosaccharide facilitates the exploration of intricate processes underlying GM2 ganglioside metabolism. Synonyms: GM2 Ganglioside oligosaccharide. Molecular formula: C31H51N2O24Na. Mole weight: 858.73. | |
| (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase | This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively. Asialo-GM3 and lactosylceramide are also substrates, but glycoproteins and oligosaccharides are not substrates. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-α-neuraminyl)-(2?3)-O-β-D-galactopyranosyl-(1?4)-β-D-glucopyranosyl]-ceramide 1,4-β-N-acetyl-D-galactosaminyltransferase acetylgalactosa. Enzyme Commission Number: EC 2.4.1.92. CAS No. 67338-98-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2632; (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase; EC 2.4.1.92; 67338-98-1; uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-gal. | |
| Native Human Lysogangliosides | Lyso-gangliosides are prepared by removing glycolipid enzymatically from natural gangliosides. They can be used to analyze various cell function, such as cell proliferation, differentiation, apoptosis, signal transduction, etc. It can also be used as a material of ganglioside derivatives in RI labeling, fluorescence labeling, immobilization since they have free amino group in sphingosine. Group: Enzymes. Synonyms: Lysogangliosides; Lyso-GM2; Lyso-gangliosides. Purity: Greater than 95% by TLC. Lysogangliosides. Storage: -20°C. Form: Lyophilized. Source: Human brain ganglioside GM2. Species: Human. Lysogangliosides; Lyso-GM2; Lyso-gangliosides. Cat No: NATE-0888. | |
| D-Idose - Aqueous solution | D-Idose - Aqueous solution, a highly significant offering within the biomedical sector, assumes a critical position. Predominantly employed in addressing metabolic irregularities like GM2 gangliosidosis, its primary function revolves around regulatory modulation of enzymatic activities. Moreover, its utility extends to expediting diagnostic techniques and facilitating advanced investigations into distinct cellular mechanisms. CAS No. 5978-95-0. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| GM2-Oligosaccharide-spacer-NH2 ammonium | GM2-Oligosaccharide-spacer-NH2 ammonium is a vital compound used in biomedicine. Its application lies in the treatment of GM2 gangliosidoses, a group of genetic disorders caused by the deficiency of vital enzymes. Synonyms: GalNAcb-4(NeuAca2-3)Galb-4Glcb-NAc-spacer-NH2. Molecular formula: C44H75N7O27.NH3. Mole weight: 1151.13. | |
| Ibiglustat | Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat; SAR402671; GZ402671. CAS No. 1401090-53-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743. | |
| Ibiglustat succinate | Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat succinate can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat succinate; SAR402671 succinate; GZ402671 succinate. CAS No. 1629063-80-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743B. | |
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