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Gap 27, a peptide derived from connexin 43, is a gap junction inhibitor. Synonyms: H-Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile-OH; L-seryl-L-arginyl-L-prolyl-L-threonyl-L-alpha-glutamyl-L-lysyl-L-threonyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-isoleucine; Gap27; Gap-27. Grades: 98%. CAS No. 198284-64-9. Molecular formula: C60H101N15O17. Mole weight: 1304.53.
Gap 27
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 198284-64-9. Molecular formula: C60H101N15O17. Mole weight: 1304.55. Purity: 0.9803. Product ID: ACM198284649. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gap-2.
Gap 27
Gap 27. Group: Biochemicals. Grades: Purified. CAS No. 198284-64-9. Pack Sizes: 1mg. US Biological Life Sciences.
Alfa Chemistry offers high-purity 4-(Dicyanomethylene)-2-methyl-6-[2-(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)vinyl]-4H-pyran products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: The dcm dyes are useful for laser oscillation and a red dopant for an organic light-emitting diode device. this dye is a low band gap material with good efficiency and long lifetime. Group: Organic light-emitting diode (oled) materials. Alternative Names: DCM 2 4-(Dicyanomethylene)-2-[2-(julolidin-9-yl)vinyl]-6-methyl-4H-pyran. CAS No. 51325-95-2. Product ID: 2-[2-[(E)-2-(1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)ethenyl]-6-methylpyran-4-ylidene]propanedinitrile. Molecular formula: 355.44. Mole weight: C23H21N3O. CC1=CC (=C (C#N)C#N)C=C (O1)C=CC2=CC3=C4C (=C2)CCCN4CCC3. InChI=1S/C23H21N3O/c1-16-10-20 (21 (14-24) 15-25) 13-22 (27-16) 7-6-17-11-18-4-2-8-26-9-3-5-19 (12-17) 23 (18) 26/h6-7, 10-13H, 2-5, 8-9H2, 1H3/b7-6+. ZNJRONVKWRHYBF-VOTSOKGWSA-N. >97.0%(HPLC)(N).
9,9-Dioctyl-9H-9-silafluorene-2,7-bis(boronic acid pinacol ester). Uses: This material is used in the synthesis of low-band gap photovoltaic polymer materials that give power conversion efficiences of approx 3%. Group: Synthetic tools and reagents. Alternative Names: 9,9-Dioctyl-2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-9-silafluorene, 5,5-Dioctyl-3,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5H-dibenzo[b,d]silole. CAS No. 958293-23-7. Pack Sizes: Packaging 500 mg in glass insert. Product ID: 2-[5,5-dioctyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b][1]benzosilol-7-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. Molecular formula: 658.64. Mole weight: C40H64B2O4Si. CCCCCCCC[Si]1 (CCCCCCCC)c2cc (ccc2-c3ccc (cc13)B4OC (C) (C)C (C) (C)O4)B5OC (C) (C)C (C) (C)O5. 1S / C40H64B2O4Si / c1-11-13-15-17-19-21-27-47 (28-22-20-18-16-14-12-2) 35-29-31 (41-43-37 (3, 4) 38 (5, 6) 44-41) 23-25-33 (35) 34-26-24-32 (30-36 (34) 47) 42-45-39 (7, 8) 40 (9, 10) 46-42 / h23-26, 29-30H, 11-22, 27-28H2, 1-10H3. QLOFNQWFMMGWBX-UHFFFAOYSA-N. ≥ 97%.
D131 dye
D131 dye is an indoline based organic dye that has a large band-gap and can be used as a sensitizer in organic electronics. It shows a power conversion efficiency of 5.6% and can enhance photo-excitation of the electrochemical devices. Uses: D131 can be used in dye sensitized solar cells (dsscs) as a photosensitizer with high charge mobility and absorption coefficient. Group: Organic solar cell (opv) materials. Alternative Names: 2-Cyano-3-[4-[4-(2,2-diphenylethenyl)phenyl]-1,2,3,3a,4,8b-hexahydrocyclopent[b]indol-7-yl]-2-propenoic acid. Pack Sizes: 200 mg in glass insert. Molecular formula: 508.61. OC (/C (C#N) =C/C (C=C1) =CC2=C1N (C3=CC=C (C=C (C4=CC=CC=C4) C5=CC=CC=C5) C=C3) C6C2CCC6) =O. 1S/C35H28N2O2/c36-23-28 (35 (38) 39) 20-25-16-19-34-32 (22-25) 30-12-7-13-33 (30) 37 (34) 29-17-14-24 (15-18-29) 21-31 (26-8-3-1-4-9-26) 27-10-5-2-6-11-27/h1-6, 8-11, 14-22, 30, 33H, 7, 12-13H2, (H, 38, 39) /b28-20+, GOTRYMLNXIJMCB-VFCFBJKWSA-N. GOTRYMLNXIJMCB-VFCFBJKWSA-N.
Canavanine, nitric oxide synthase inhibitor, is an analog of arginine. Both are imported into the cell via the same high-affinity permease, which is encoded by the can1 locus. High-level resistance to canavanine occurs exclusively because of mutation at this locus, but low-level resistance can arise at a number of other loci.Because canavinine is a competitive inhibitor, arginine must be excluded from media used for testing sensitivity to the drug. Canavanine resistance must also be scored under high-nitrogen conditions, such as those provided by SD or SC medium, since the CAN1 permease will then provide the only entry route to the cell for arginine and canavanine. In the presence of low-nitrogen conditions, effectively those provided by YPD medium, the general amino acid permease (GAP) system is induced and arginine and canavanine can also be taken up by this route. In addition, Can r Arg-auxotrophs are viable on YPD but are inviable on synthetic media because they are unable to take up arginine. Group: Biochemicals. Alternative Names: Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid. Grades: Molecular Biology Grade. CAS No. 2219-31-0. Pack Sizes: 1g. Molecular Formula: C5H12N4O3; H2SO4, Molecular Weight: 274.25. US Biological Life Sciences.
Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Synonyms: HKI-272; HKI 272; HKI272; PB-272; PB 272; PB 272. Grades: >98%. CAS No. 698387-09-6. Molecular formula: C30H29ClN6O3. Mole weight: 557.051.
Quaterrylene
Quaterrylene. Uses: A promising candidate for organic electronic applications because it absorbs a broad spectrum of uv and visible light, while possessing excellent thermal and oxidative stability and a low homo-lumo band gap. organic electronics photovoltaic components graphene nanoribbons electroactive polymers. Group: Carbon nano materials organic light-emitting diode (oled) materials. Alternative Names: Benzo[1,2,3-cd: 4,5,6-c'd']diperylene. CAS No. 188-73-8. Pack Sizes: 25 mg in poly bottle. Product ID: undecacyclo[20.12.2.22, 5.16, 10.123, 27.03, 18.04, 15.019, 35.032, 36.014, 38.031, 37]tetraconta-1(35), 2, 4, 6, 8, 10(38), 11, 13, 15, 17, 19, 21, 23, 25, 27(37), 28, 30, 32(36), 33, 39-icosaene. Molecular formula: 500.59. Mole weight: C40H20. C12=CC=CC (C3=C (C4=CC=C5C6=CC=C (C7=CC=C8) C9=C (C%10=C7C8=CC=C%10) C=CC%11C96) C5=C%11C=C3) =C1C4=CC=C2. 1S / C40H22 / c1-5-21-6-2-10-24-28-14-18-32-34-20-1 6-30-26-12-4-8-22-7-3-11-25 (36 (22) 26) 29-15-19-33 (40 (34) 38 (29) 30) 31-17-13-27 (37 (28) 39 (31) 32) 23 (9-1) 35 (21) 24 / h1-20, 31, 39H, BWASZFNXSFVOCT-UHFFFAOYSA-N. BWASZFNXSFVOCT-UHFFFAOYSA-N.
Small gap fullerenes
Insoluble small gap fullerenes can be extracted into organic solvents by simple chemical redox process. Uses: Small gap fullerenes can be used as doping agents on polyaniline (pani) for organic electronics applications. Group: Supercapacitorscarbon nano materials organic solar cell (opv) materials. Pack Sizes: 1 g in glass bottle. Molecular formula: 912.81. Mole weight: Linear Formula C60(C8H15NO2)x. C=1=C2c3c4C=1c5c6c7c8c9c% 10c% 11c% 12c% 13C% 14=[C]% 10=C% 15c% 16c% 17c% 14c% 18c% 13c% 19c% 20c% 12c% 21c% 11c (c% 22c% 23c% 24c (C2=[C]7% 15% 22) c% 25c3c% 26c% 27c4c% 28c5c (c6% 16) c% 29c% 17c% 30c% 18c% 31c% 19c% 32c% 20c (c% 21% 23) c% 33c% 24c% 34c% 25c% 26c% 35c% 36c% 27c% 28c% 29c% 37c% 30c% 31c% 38c% 32c% 33c% 34c% 35c% 38c% 36% 37) c89. 1S/C. OKTJSMMVPCPJKN-UHFFFAOYSA-N.
TAT-Gap19
TAT-Gap19 is a brain penetrating Cx43 hemichannel blocker (IC50 ~7 μM) with no significant affinity for gap junctions or Panx1 channels. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutaminyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-lysine. Grades: 97%. CAS No. 1507930-54-2. Molecular formula: C119H212N46O26. Mole weight: 2703.28.
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