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Gefitinib hydrochloride Gefitinib Hcl(ZD-1839 Hcl) is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Synonyms: Iressa hydrochloride; ZD 1839 hydrochloride; ZD-1839 hydrochloride; ZD1839 hydrochloride. Grades: >98%. CAS No. 184475-55-6. Molecular formula: C22H25Cl2FN4O3. Mole weight: 483.36. BOC Sciences 10
Gefitinib hydrochloride Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD-1839 hydrochloride. CAS No. 184475-55-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895A. MedChemExpress MCE

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